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BCLC Stage B Hepatocellular Carcinoma

MedGen UID:
859573
Concept ID:
C3899979
Neoplastic Process
Synonym: Barcelona Clinic Liver Cancer Stage B Hepatocellular Carcinoma

Definition

Intermediate hepatocellular carcinoma. Patients may benefit from chemoembolization. (HPB (Oxford) 2005; 7(1):35-41) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBCLC Stage B Hepatocellular Carcinoma

Professional guidelines

PubMed

Roccarina D, Majumdar A, Thorburn D, Davidson BR, Tsochatzis E, Gurusamy KS
Cochrane Database Syst Rev 2017 Mar 10;3(3):CD011649. doi: 10.1002/14651858.CD011649.pub2. PMID: 28281295Free PMC Article
Arizumi T, Ueshima K, Iwanishi M, Minami T, Chishina H, Kono M, Takita M, Kitai S, Inoue T, Yada N, Hagiwara S, Minami Y, Ida H, Sakurai T, Kitano M, Nishida N, Kudo M
Dig Dis 2016;34(6):671-678. Epub 2016 Oct 17 doi: 10.1159/000448834. PMID: 27750236
Kudo M, Arizumi T, Ueshima K, Sakurai T, Kitano M, Nishida N
Dig Dis 2015 Oct;33(6):751-8. Epub 2015 Oct 21 doi: 10.1159/000439290. PMID: 26488473

Recent clinical studies

Etiology

Han JE, Cho HJ, Cheong JY, Lim SG, Yang MJ, Noh CK, Lee GH, Kim SS
World J Gastroenterol 2023 Dec 21;29(47):6122-6137. doi: 10.3748/wjg.v29.i47.6122. PMID: 38186683Free PMC Article
Saeki I, Yamasaki T, Yamauchi Y, Kawaoka T, Uchikawa S, Hiramatsu A, Aikata H, Kobayashi K, Kondo T, Ogasawara S, Chiba T, Kawano R, Chayama K, Kato N, Takami T
Cancer Med 2023 May;12(9):10625-10635. Epub 2023 Mar 23 doi: 10.1002/cam4.5810. PMID: 36951579Free PMC Article
Ranganathan S, Gabr A, Entezari P, Gordon AC, Riaz A, Desai K, Thornburg B, Kulik L, Kalyan A, Salem R, Lewandowski RJ
J Vasc Interv Radiol 2023 Jun;34(6):968-975. Epub 2023 Feb 13 doi: 10.1016/j.jvir.2022.11.036. PMID: 36791957
Zhang M, Lai W, Zhang J, Hu B, Huang L, Chu C
Dis Markers 2022;2022:6957580. Epub 2022 Jul 6 doi: 10.1155/2022/6957580. PMID: 35845129Free PMC Article
Jianyong L, Lunan Y, Wentao W, Yong Z, Bo L, Tianfu W, Minqing X, Jiaying Y
Medicine (Baltimore) 2014 Nov;93(26):e180. doi: 10.1097/MD.0000000000000180. PMID: 25474433Free PMC Article

Diagnosis

Tai D, Loke K, Gogna A, Kaya NA, Tan SH, Hennedige T, Ng D, Irani F, Lee J, Lim JQ, Too CW, Ng MCH, Tham CK, Lam J, Koo SL, Chong HS, Goh GB, Huang HL, Venkatanarasimha N, Lo R, Chow PKH, Goh BKP, Chung A, Toh HC, Thng CH, Lim TKH, Yeong J, Zhai W, Chan CY, Choo SP
Lancet Gastroenterol Hepatol 2021 Dec;6(12):1025-1035. Epub 2021 Oct 23 doi: 10.1016/S2468-1253(21)00305-8. PMID: 34695377
Lee IC, Hung YW, Liu CA, Lee RC, Su CW, Huo TI, Li CP, Chao Y, Lin HC, Hou MC, Huang YH
Liver Int 2019 Sep;39(9):1704-1712. Epub 2019 Jul 30 doi: 10.1111/liv.14194. PMID: 31319016
Liu W, Zhou JG, Sun Y, Zhang L, Xing BC
J Gastrointest Surg 2015 Jul;19(7):1271-80. Epub 2015 May 6 doi: 10.1007/s11605-015-2811-6. PMID: 25943910
Farinati F, Vanin V, Giacomin A, Pozzan C, Cillo U, Vitale A, Di Nolfo AM, Del Poggio P, Benvegnu' L, Rapaccini G, Zoli M, Borzio F, Giannini EG, Caturelli E, Trevisani F; Italian Liver Cancer (ITA.LI.CA) group
Liver Int 2015 Jan;35(1):223-31. Epub 2014 Aug 27 doi: 10.1111/liv.12649. PMID: 25074434
Qian H, Wei M, Qiu H, Wu J, Liu B, Lyu A, Liu Q, Li C, Leng J, Zhang J, Hao C
Chin Med J (Engl) 2014;127(24):4171-6. PMID: 25533817

Therapy

Saeki I, Yamasaki T, Yamauchi Y, Kawaoka T, Uchikawa S, Hiramatsu A, Aikata H, Kobayashi K, Kondo T, Ogasawara S, Chiba T, Kawano R, Chayama K, Kato N, Takami T
Cancer Med 2023 May;12(9):10625-10635. Epub 2023 Mar 23 doi: 10.1002/cam4.5810. PMID: 36951579Free PMC Article
Ranganathan S, Gabr A, Entezari P, Gordon AC, Riaz A, Desai K, Thornburg B, Kulik L, Kalyan A, Salem R, Lewandowski RJ
J Vasc Interv Radiol 2023 Jun;34(6):968-975. Epub 2023 Feb 13 doi: 10.1016/j.jvir.2022.11.036. PMID: 36791957
Tai D, Loke K, Gogna A, Kaya NA, Tan SH, Hennedige T, Ng D, Irani F, Lee J, Lim JQ, Too CW, Ng MCH, Tham CK, Lam J, Koo SL, Chong HS, Goh GB, Huang HL, Venkatanarasimha N, Lo R, Chow PKH, Goh BKP, Chung A, Toh HC, Thng CH, Lim TKH, Yeong J, Zhai W, Chan CY, Choo SP
Lancet Gastroenterol Hepatol 2021 Dec;6(12):1025-1035. Epub 2021 Oct 23 doi: 10.1016/S2468-1253(21)00305-8. PMID: 34695377
Liu W, Zhou JG, Sun Y, Zhang L, Xing BC
J Gastrointest Surg 2015 Jul;19(7):1271-80. Epub 2015 May 6 doi: 10.1007/s11605-015-2811-6. PMID: 25943910
Jianyong L, Lunan Y, Wentao W, Yong Z, Bo L, Tianfu W, Minqing X, Jiaying Y
Medicine (Baltimore) 2014 Nov;93(26):e180. doi: 10.1097/MD.0000000000000180. PMID: 25474433Free PMC Article

Prognosis

Han JE, Cho HJ, Cheong JY, Lim SG, Yang MJ, Noh CK, Lee GH, Kim SS
World J Gastroenterol 2023 Dec 21;29(47):6122-6137. doi: 10.3748/wjg.v29.i47.6122. PMID: 38186683Free PMC Article
Saeki I, Yamasaki T, Yamauchi Y, Kawaoka T, Uchikawa S, Hiramatsu A, Aikata H, Kobayashi K, Kondo T, Ogasawara S, Chiba T, Kawano R, Chayama K, Kato N, Takami T
Cancer Med 2023 May;12(9):10625-10635. Epub 2023 Mar 23 doi: 10.1002/cam4.5810. PMID: 36951579Free PMC Article
Ranganathan S, Gabr A, Entezari P, Gordon AC, Riaz A, Desai K, Thornburg B, Kulik L, Kalyan A, Salem R, Lewandowski RJ
J Vasc Interv Radiol 2023 Jun;34(6):968-975. Epub 2023 Feb 13 doi: 10.1016/j.jvir.2022.11.036. PMID: 36791957
Liu W, Zhou JG, Sun Y, Zhang L, Xing BC
J Gastrointest Surg 2015 Jul;19(7):1271-80. Epub 2015 May 6 doi: 10.1007/s11605-015-2811-6. PMID: 25943910
Jianyong L, Lunan Y, Wentao W, Yong Z, Bo L, Tianfu W, Minqing X, Jiaying Y
Medicine (Baltimore) 2014 Nov;93(26):e180. doi: 10.1097/MD.0000000000000180. PMID: 25474433Free PMC Article

Clinical prediction guides

Han JE, Cho HJ, Cheong JY, Lim SG, Yang MJ, Noh CK, Lee GH, Kim SS
World J Gastroenterol 2023 Dec 21;29(47):6122-6137. doi: 10.3748/wjg.v29.i47.6122. PMID: 38186683Free PMC Article
Zhang M, Lai W, Zhang J, Hu B, Huang L, Chu C
Dis Markers 2022;2022:6957580. Epub 2022 Jul 6 doi: 10.1155/2022/6957580. PMID: 35845129Free PMC Article
Tai D, Loke K, Gogna A, Kaya NA, Tan SH, Hennedige T, Ng D, Irani F, Lee J, Lim JQ, Too CW, Ng MCH, Tham CK, Lam J, Koo SL, Chong HS, Goh GB, Huang HL, Venkatanarasimha N, Lo R, Chow PKH, Goh BKP, Chung A, Toh HC, Thng CH, Lim TKH, Yeong J, Zhai W, Chan CY, Choo SP
Lancet Gastroenterol Hepatol 2021 Dec;6(12):1025-1035. Epub 2021 Oct 23 doi: 10.1016/S2468-1253(21)00305-8. PMID: 34695377
Farinati F, Vanin V, Giacomin A, Pozzan C, Cillo U, Vitale A, Di Nolfo AM, Del Poggio P, Benvegnu' L, Rapaccini G, Zoli M, Borzio F, Giannini EG, Caturelli E, Trevisani F; Italian Liver Cancer (ITA.LI.CA) group
Liver Int 2015 Jan;35(1):223-31. Epub 2014 Aug 27 doi: 10.1111/liv.12649. PMID: 25074434
Jianyong L, Lunan Y, Wentao W, Yong Z, Bo L, Tianfu W, Minqing X, Jiaying Y
Medicine (Baltimore) 2014 Nov;93(26):e180. doi: 10.1097/MD.0000000000000180. PMID: 25474433Free PMC Article

Recent systematic reviews

Liu W, Zhou JG, Sun Y, Zhang L, Xing BC
J Gastrointest Surg 2015 Jul;19(7):1271-80. Epub 2015 May 6 doi: 10.1007/s11605-015-2811-6. PMID: 25943910

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