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Acute motor and sensory axonal neuropathy

MedGen UID:
859705
Concept ID:
C3900111
Disease or Syndrome
Synonyms: Acute Motor and Sensory Axonal Neuropathy; acute motor and sensory axonal neuropathy; Acute motor sensory axonal Guillain-Barré syndrome; Acute motor sensory axonal neuropathy; Acute motor-sensory axonal GBS; acute motor-sensory axonal GBS; acute motor-sensory axonal Guillain-Barre syndrome; Acute motor-sensory axonal Guillain-Barré syndrome; acute motor-sensory axonal Guillain-Barré syndrome; Acute Motor-Sensory Axonal Neuropathy; acute motor-sensory axonal neuropathy; AMSAN
SNOMED CT: Acute motor sensory axonal neuropathy (716722005); Acute motor sensory axonal Guillain-Barré syndrome (716722005)
Modes of inheritance:
Non-Mendelian inheritance
MedGen UID:
109109
Concept ID:
C0600599
Genetic Function
Source: Orphanet
A mode of inheritance that depends on genetic determinants in more than one gene.
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0020348
Orphanet: ORPHA98917

Definition

A motor sensory axonal form of Guillain-Barré syndrome. Patients present with muscle weakness and sensory deficits, similar to that of the more frequent demyelinating form of Guillain-Barré syndrome. As in other types of Guillain-Barré syndrome, an infectious disease precedes the onset of limb weakness in the majority of cases. Although the exact pathological mechanism is poorly understood the disease is associated with the presence of antiganglioside antibodies and may be caused by antibody-mediated primary axonal degeneration or antibody-mediated inhibition of voltage-gated sodium channels. [from SNOMEDCT_US]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAcute motor and sensory axonal neuropathy

Professional guidelines

PubMed

Uncini A, Kuwabara S
Clin Neurophysiol 2012 Aug;123(8):1487-95. Epub 2012 Apr 4 doi: 10.1016/j.clinph.2012.01.025. PMID: 22480600
Sederholm BH
Semin Neurol 2010 Sep;30(4):365-72. Epub 2010 Oct 12 doi: 10.1055/s-0030-1267280. PMID: 20941669
Finsterer J
Acta Neurol Scand 2005 Aug;112(2):115-25. doi: 10.1111/j.1600-0404.2005.00448.x. PMID: 16008538

Recent clinical studies

Etiology

Siddiqui M, Majid S, Yusuf H, Mateen F
J Coll Physicians Surg Pak 2022 Mar;32(3):364-368. doi: 10.29271/jcpsp.2022.03.364. PMID: 35148591
I Espiritu A, Separa KJNJ, Milla FJC, Adiao KJB, Leochico CFD, Jamora RDG
Neurol Res 2021 Dec;43(12):995-1004. Epub 2021 Jul 6 doi: 10.1080/01616412.2021.1948750. PMID: 34229572
Kılıç B, Güngör S, Özgör B
Turk J Pediatr 2019;61(2):200-208. doi: 10.24953/turkjped.2019.02.008. PMID: 32077646
Gómez Á, Díaz A, Carrión-Penagos J, Reyes J, Reyes S
J Peripher Nerv Syst 2019 Sep;24(3):268-271. Epub 2019 Aug 18 doi: 10.1111/jns.12340. PMID: 31386254
Peric S, Berisavac I, Stojiljkovic Tamas O, Rajic S, Babic M, Cvijanovic M, Dominovic-Kovacevic A, Basta I, Beslac-Bumbasirevic L, Lavrnic D
J Peripher Nerv Syst 2016 Jun;21(2):105-10. doi: 10.1111/jns.12163. PMID: 26880714

Diagnosis

Shang P, Zhu M, Wang Y, Zheng X, Wu X, Zhu J, Feng J, Zhang HL
J Neurol 2021 Jul;268(7):2402-2419. Epub 2020 Mar 5 doi: 10.1007/s00415-020-09742-2. PMID: 32140865
Fujimura H
Handb Clin Neurol 2013;115:383-402. doi: 10.1016/B978-0-444-52902-2.00021-7. PMID: 23931791
Arcila-Londono X, Lewis RA
Semin Neurol 2012 Jul;32(3):179-86. Epub 2012 Nov 1 doi: 10.1055/s-0032-1329196. PMID: 23117942
Vucic S, Kiernan MC, Cornblath DR
J Clin Neurosci 2009 Jun;16(6):733-41. Epub 2009 Apr 7 doi: 10.1016/j.jocn.2008.08.033. PMID: 19356935
Hughes RA, Cornblath DR
Lancet 2005 Nov 5;366(9497):1653-66. doi: 10.1016/S0140-6736(05)67665-9. PMID: 16271648

Therapy

Shang P, Zhu M, Wang Y, Zheng X, Wu X, Zhu J, Feng J, Zhang HL
J Neurol 2021 Jul;268(7):2402-2419. Epub 2020 Mar 5 doi: 10.1007/s00415-020-09742-2. PMID: 32140865
Uncini A, Notturno F, Capasso M
Muscle Nerve 2013 Oct;48(4):484-7. doi: 10.1002/mus.23881. PMID: 23625341
Vucic S, Kiernan MC, Cornblath DR
J Clin Neurosci 2009 Jun;16(6):733-41. Epub 2009 Apr 7 doi: 10.1016/j.jocn.2008.08.033. PMID: 19356935
Hughes RA, Cornblath DR
Lancet 2005 Nov 5;366(9497):1653-66. doi: 10.1016/S0140-6736(05)67665-9. PMID: 16271648
Ensrud ER, Krivickas LS
Phys Med Rehabil Clin N Am 2001 May;12(2):321-34, ix. PMID: 11345010

Prognosis

Freiha J, Zoghaib R, Makhoul K, Maalouf N, Riachi N, Chalah MA, Ayache SS, Ahdab R
Clin Neurophysiol 2021 May;132(5):1157-1162. Epub 2021 Mar 13 doi: 10.1016/j.clinph.2021.02.013. PMID: 33780722
Kılıç B, Güngör S, Özgör B
Turk J Pediatr 2019;61(2):200-208. doi: 10.24953/turkjped.2019.02.008. PMID: 32077646
Uncini A, Kuwabara S
Clin Neurophysiol 2012 Aug;123(8):1487-95. Epub 2012 Apr 4 doi: 10.1016/j.clinph.2012.01.025. PMID: 22480600
Hughes RA, Cornblath DR
Lancet 2005 Nov 5;366(9497):1653-66. doi: 10.1016/S0140-6736(05)67665-9. PMID: 16271648
Ensrud ER, Krivickas LS
Phys Med Rehabil Clin N Am 2001 May;12(2):321-34, ix. PMID: 11345010

Clinical prediction guides

Siddiqui M, Majid S, Yusuf H, Mateen F
J Coll Physicians Surg Pak 2022 Mar;32(3):364-368. doi: 10.29271/jcpsp.2022.03.364. PMID: 35148591
I Espiritu A, Separa KJNJ, Milla FJC, Adiao KJB, Leochico CFD, Jamora RDG
Neurol Res 2021 Dec;43(12):995-1004. Epub 2021 Jul 6 doi: 10.1080/01616412.2021.1948750. PMID: 34229572
Freiha J, Zoghaib R, Makhoul K, Maalouf N, Riachi N, Chalah MA, Ayache SS, Ahdab R
Clin Neurophysiol 2021 May;132(5):1157-1162. Epub 2021 Mar 13 doi: 10.1016/j.clinph.2021.02.013. PMID: 33780722
Kılıç B, Güngör S, Özgör B
Turk J Pediatr 2019;61(2):200-208. doi: 10.24953/turkjped.2019.02.008. PMID: 32077646
Peric S, Berisavac I, Stojiljkovic Tamas O, Rajic S, Babic M, Cvijanovic M, Dominovic-Kovacevic A, Basta I, Beslac-Bumbasirevic L, Lavrnic D
J Peripher Nerv Syst 2016 Jun;21(2):105-10. doi: 10.1111/jns.12163. PMID: 26880714

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