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Increased susceptibility to B-cell lymphoma

MedGen UID:
862534
•Concept ID:
C4014097
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIncreased susceptibility to B-cell lymphoma

Professional guidelines

PubMed

IKAROS-Associated Diseases in 2020: Genotypes, Phenotypes, and Outcomes in Primary Immune Deficiency/Inborn Errors of Immunity.
Kuehn HS, Nunes-Santos CJ, Rosenzweig SD
J Clin Immunol 2021 Jan;41(1):1-10. Epub 2021 Jan 3 doi: 10.1007/s10875-020-00936-x. PMID: 33392855
Biology and Treatment Paradigms in T Cell Acute Lymphoblastic Leukemia in Older Adolescents and Adults.
Patel AA, Thomas J, Rojek AE, Stock W
Curr Treat Options Oncol 2020 May 28;21(7):57. doi: 10.1007/s11864-020-00757-5. PMID: 32468488
Multiple myeloma: diagnosis and treatment.
Nau KC, Lewis WD
Am Fam Physician 2008 Oct 1;78(7):853-9. PMID: 18841734

Recent clinical studies

Etiology

Infectious triggers and novel therapeutic opportunities in childhood B cell leukaemia.
Cobaleda C, Vicente-Dueñas C, Sanchez-Garcia I
Nat Rev Immunol 2021 Sep;21(9):570-581. Epub 2021 Feb 8 doi: 10.1038/s41577-021-00505-2. PMID: 33558682
B cells in the pathogenesis of primary Sjögren syndrome.
Nocturne G, Mariette X
Nat Rev Rheumatol 2018 Mar;14(3):133-145. Epub 2018 Feb 8 doi: 10.1038/nrrheum.2018.1. PMID: 29416129
Immunomodulation and lymphoma in humans.
Ponce RA, Gelzleichter T, Haggerty HG, Heidel S, Holdren MS, Lebrec H, Mellon RD, Pallardy M
J Immunotoxicol 2014 Jan-Mar;11(1):1-12. Epub 2013 Jun 7 doi: 10.3109/1547691X.2013.798388. PMID: 23746314
Genetic susceptibility to lymphoma.
Skibola CF, Curry JD, Nieters A
Haematologica 2007 Jul;92(7):960-9. doi: 10.3324/haematol.11011. PMID: 17606447Free PMC Article
AIDS and oncogenesis.
Ziegler JL
Front Radiat Ther Oncol 1985;19:99-104. doi: 10.1159/000429349. PMID: 3884453

Diagnosis

A Deep Insight Into CAR-T Cell Therapy in Non-Hodgkin Lymphoma: Application, Opportunities, and Future Directions.
Marofi F, Rahman HS, Achmad MH, Sergeevna KN, Suksatan W, Abdelbasset WK, Mikhailova MV, Shomali N, Yazdanifar M, Hassanzadeh A, Ahmadi M, Motavalli R, Pathak Y, Izadi S, Jarahian M
Front Immunol 2021;12:681984. Epub 2021 Jun 23 doi: 10.3389/fimmu.2021.681984. PMID: 34248965Free PMC Article
Hairy cell leukemia: present and future directions.
Kreitman RJ
Leuk Lymphoma 2019 Dec;60(12):2869-2879. Epub 2019 May 9 doi: 10.1080/10428194.2019.1608536. PMID: 31068044Free PMC Article
The Function of MicroRNAs in B-Cell Development, Lymphoma, and Their Potential in Clinical Practice.
Zheng B, Xi Z, Liu R, Yin W, Sui Z, Ren B, Miller H, Gong Q, Liu C
Front Immunol 2018;9:936. Epub 2018 Apr 30 doi: 10.3389/fimmu.2018.00936. PMID: 29760712Free PMC Article
Pediatric Extranodal Lymphoma.
Chung EM, Pavio M
Radiol Clin North Am 2016 Jul;54(4):727-46. doi: 10.1016/j.rcl.2016.03.004. PMID: 27265605
Common Variable Immunodeficiency.
Saikia B, Gupta S
Indian J Pediatr 2016 Apr;83(4):338-44. Epub 2016 Feb 12 doi: 10.1007/s12098-016-2038-x. PMID: 26868026

Therapy

Kinase-impaired BTK mutations are susceptible to clinical-stage BTK and IKZF1/3 degrader NX-2127.
Montoya S, Bourcier J, Noviski M, Lu H, Thompson MC, Chirino A, Jahn J, Sondhi AK, Gajewski S, Tan YSM, Yung S, Urban A, Wang E, Han C, Mi X, Kim WJ, Sievers Q, Auger P, Bousquet H, Brathaban N, Bravo B, Gessner M, Guiducci C, Iuliano JN, Kane T, Mukerji R, Reddy PJ, Powers J, Sanchez Garcia de Los Rios M, Ye J, Barrientos Risso C, Tsai D, Pardo G, Notti RQ, Pardo A, Affer M, Nawaratne V, Totiger TM, Pena-Velasquez C, Rhodes JM, Zelenetz AD, Alencar A, Roeker LE, Mehta S, Garippa R, Linley A, Soni RK, Skånland SS, Brown RJ, Mato AR, Hansen GM, Abdel-Wahab O, Taylor J
Science 2024 Feb 2;383(6682):eadi5798. doi: 10.1126/science.adi5798. PMID: 38301010
A Deep Insight Into CAR-T Cell Therapy in Non-Hodgkin Lymphoma: Application, Opportunities, and Future Directions.
Marofi F, Rahman HS, Achmad MH, Sergeevna KN, Suksatan W, Abdelbasset WK, Mikhailova MV, Shomali N, Yazdanifar M, Hassanzadeh A, Ahmadi M, Motavalli R, Pathak Y, Izadi S, Jarahian M
Front Immunol 2021;12:681984. Epub 2021 Jun 23 doi: 10.3389/fimmu.2021.681984. PMID: 34248965Free PMC Article
Advances in Molecular Biology and Targeted Therapy of Mantle Cell Lymphoma.
Klener P
Int J Mol Sci 2019 Sep 8;20(18) doi: 10.3390/ijms20184417. PMID: 31500350Free PMC Article
Hairy cell leukemia: present and future directions.
Kreitman RJ
Leuk Lymphoma 2019 Dec;60(12):2869-2879. Epub 2019 May 9 doi: 10.1080/10428194.2019.1608536. PMID: 31068044Free PMC Article
AIDS and oncogenesis.
Ziegler JL
Front Radiat Ther Oncol 1985;19:99-104. doi: 10.1159/000429349. PMID: 3884453

Prognosis

Increased activation of PI3 kinase-δ predisposes to B-cell lymphoma.
Durandy A, Kracker S
Blood 2020 Feb 27;135(9):638-643. doi: 10.1182/blood.2019002072. PMID: 31942637
Hairy cell leukemia: present and future directions.
Kreitman RJ
Leuk Lymphoma 2019 Dec;60(12):2869-2879. Epub 2019 May 9 doi: 10.1080/10428194.2019.1608536. PMID: 31068044Free PMC Article
The Function of MicroRNAs in B-Cell Development, Lymphoma, and Their Potential in Clinical Practice.
Zheng B, Xi Z, Liu R, Yin W, Sui Z, Ren B, Miller H, Gong Q, Liu C
Front Immunol 2018;9:936. Epub 2018 Apr 30 doi: 10.3389/fimmu.2018.00936. PMID: 29760712Free PMC Article
Genetic and epigenetic determinants of B-cell lymphoma evolution.
Izzo F, Landau DA
Curr Opin Hematol 2016 Jul;23(4):392-401. doi: 10.1097/MOH.0000000000000258. PMID: 27135978
Susceptibility of patients with rheumatic diseases to B-cell non-Hodgkin lymphoma.
Dias C, Isenberg DA
Nat Rev Rheumatol 2011 Jun;7(6):360-8. doi: 10.1038/nrrheum.2011.62. PMID: 21637317

Clinical prediction guides

BCL-2 expression promotes immunosuppression in chronic lymphocytic leukemia by enhancing regulatory T cell differentiation and cytotoxic T cell exhaustion.
Liu L, Cheng X, Yang H, Lian S, Jiang Y, Liang J, Chen X, Mo S, Shi Y, Zhao S, Li J, Jiang R, Yang DH, Wu Y
Mol Cancer 2022 Feb 22;21(1):59. doi: 10.1186/s12943-022-01516-w. PMID: 35193595Free PMC Article
Increased activation of PI3 kinase-δ predisposes to B-cell lymphoma.
Durandy A, Kracker S
Blood 2020 Feb 27;135(9):638-643. doi: 10.1182/blood.2019002072. PMID: 31942637
B cells in the pathogenesis of primary Sjögren syndrome.
Nocturne G, Mariette X
Nat Rev Rheumatol 2018 Mar;14(3):133-145. Epub 2018 Feb 8 doi: 10.1038/nrrheum.2018.1. PMID: 29416129
Genetic and epigenetic determinants of B-cell lymphoma evolution.
Izzo F, Landau DA
Curr Opin Hematol 2016 Jul;23(4):392-401. doi: 10.1097/MOH.0000000000000258. PMID: 27135978
Immunomodulation and lymphoma in humans.
Ponce RA, Gelzleichter T, Haggerty HG, Heidel S, Holdren MS, Lebrec H, Mellon RD, Pallardy M
J Immunotoxicol 2014 Jan-Mar;11(1):1-12. Epub 2013 Jun 7 doi: 10.3109/1547691X.2013.798388. PMID: 23746314

Recent systematic reviews

A Systematic Review on Predisposition to Lymphoid (B and T cell) Neoplasias in Patients With Primary Immunodeficiencies and Immune Dysregulatory Disorders (Inborn Errors of Immunity).
Riaz IB, Faridi W, Patnaik MM, Abraham RS
Front Immunol 2019;10:777. Epub 2019 Apr 16 doi: 10.3389/fimmu.2019.00777. PMID: 31057537Free PMC Article
Genetic polymorphisms in the DNA repair gene, XRCC1 associate with non-Hodgkin lymphoma susceptibility: A systematic review and meta-analysis.
Li Y, Bai O, Cui J, Li W
Eur J Med Genet 2016 Feb;59(2):91-103. Epub 2015 Dec 23 doi: 10.1016/j.ejmg.2015.12.011. PMID: 26723520
LEP and LEPR polymorphisms in non-Hodgkin lymphoma risk: a systematic review and pooled analysis.
Lin HY, Shi H, Li CY, Chen QC, Huang TB, Liu PC, Lou LM
J BUON 2015 Jan-Feb;20(1):261-8. PMID: 25778326

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