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Increased susceptibility to hematologic malignancies

MedGen UID:
863975
•Concept ID:
C4015538
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIncreased susceptibility to hematologic malignancies

Professional guidelines

PubMed

Clinical implementation of genetic testing in adults for hereditary hematologic malignancy syndromes.
Ansar S, Malcolmson J, Farncombe KM, Yee K, Kim RH, Sibai H
Genet Med 2022 Nov;24(11):2367-2379. Epub 2022 Sep 16 doi: 10.1016/j.gim.2022.08.010. PMID: 36112138
Antibiotic Management of Patients with Hematologic Malignancies: From Prophylaxis to Unusual Infections.
Moreno-Sanchez F, Gomez-Gomez B
Curr Oncol Rep 2022 Jul;24(7):835-842. Epub 2022 Mar 22 doi: 10.1007/s11912-022-01226-y. PMID: 35316843Free PMC Article
Association Between Radioactive Iodine Treatment for Pediatric and Young Adulthood Differentiated Thyroid Cancer and Risk of Second Primary Malignancies.
Pasqual E, Schonfeld S, Morton LM, Villoing D, Lee C, Berrington de Gonzalez A, Kitahara CM
J Clin Oncol 2022 May 1;40(13):1439-1449. Epub 2022 Jan 19 doi: 10.1200/JCO.21.01841. PMID: 35044839Free PMC Article

Recent clinical studies

Etiology

Association Between Radioactive Iodine Treatment for Pediatric and Young Adulthood Differentiated Thyroid Cancer and Risk of Second Primary Malignancies.
Pasqual E, Schonfeld S, Morton LM, Villoing D, Lee C, Berrington de Gonzalez A, Kitahara CM
J Clin Oncol 2022 May 1;40(13):1439-1449. Epub 2022 Jan 19 doi: 10.1200/JCO.21.01841. PMID: 35044839Free PMC Article
Germline predisposition in myeloid neoplasms: Unique genetic and clinical features of GATA2 deficiency and SAMD9/SAMD9L syndromes.
Sahoo SS, Kozyra EJ, Wlodarski MW
Best Pract Res Clin Haematol 2020 Sep;33(3):101197. Epub 2020 Jul 29 doi: 10.1016/j.beha.2020.101197. PMID: 33038986Free PMC Article
Breakthrough invasive fungal infections: Who is at risk?
Jenks JD, Cornely OA, Chen SC, Thompson GR 3rd, Hoenigl M
Mycoses 2020 Oct;63(10):1021-1032. Epub 2020 Sep 4 doi: 10.1111/myc.13148. PMID: 32744334
Hereditary Predisposition to Hematopoietic Neoplasms: When Bloodline Matters for Blood Cancers.
Mangaonkar AA, Patnaik MM
Mayo Clin Proc 2020 Jul;95(7):1482-1498. Epub 2020 Jun 19 doi: 10.1016/j.mayocp.2019.12.013. PMID: 32571604
Hematologic malignancies and Li-Fraumeni syndrome.
Swaminathan M, Bannon SA, Routbort M, Naqvi K, Kadia TM, Takahashi K, Alvarado Y, Ravandi-Kashani F, Patel KP, Champlin R, Kantarjian H, Strong L, DiNardo CD
Cold Spring Harb Mol Case Stud 2019 Feb;5(1) Epub 2019 Feb 1 doi: 10.1101/mcs.a003210. PMID: 30709875Free PMC Article

Diagnosis

Association Between Radioactive Iodine Treatment for Pediatric and Young Adulthood Differentiated Thyroid Cancer and Risk of Second Primary Malignancies.
Pasqual E, Schonfeld S, Morton LM, Villoing D, Lee C, Berrington de Gonzalez A, Kitahara CM
J Clin Oncol 2022 May 1;40(13):1439-1449. Epub 2022 Jan 19 doi: 10.1200/JCO.21.01841. PMID: 35044839Free PMC Article
Engineering the next generation of CAR-NK immunotherapies.
Biederstädt A, Rezvani K
Int J Hematol 2021 Nov;114(5):554-571. Epub 2021 Aug 28 doi: 10.1007/s12185-021-03209-4. PMID: 34453686Free PMC Article
Breakthrough invasive fungal infections: Who is at risk?
Jenks JD, Cornely OA, Chen SC, Thompson GR 3rd, Hoenigl M
Mycoses 2020 Oct;63(10):1021-1032. Epub 2020 Sep 4 doi: 10.1111/myc.13148. PMID: 32744334
MDM2 inhibition: an important step forward in cancer therapy.
Konopleva M, Martinelli G, Daver N, Papayannidis C, Wei A, Higgins B, Ott M, Mascarenhas J, Andreeff M
Leukemia 2020 Nov;34(11):2858-2874. Epub 2020 Jul 10 doi: 10.1038/s41375-020-0949-z. PMID: 32651541
Hematologic malignancies and Li-Fraumeni syndrome.
Swaminathan M, Bannon SA, Routbort M, Naqvi K, Kadia TM, Takahashi K, Alvarado Y, Ravandi-Kashani F, Patel KP, Champlin R, Kantarjian H, Strong L, DiNardo CD
Cold Spring Harb Mol Case Stud 2019 Feb;5(1) Epub 2019 Feb 1 doi: 10.1101/mcs.a003210. PMID: 30709875Free PMC Article

Therapy

Association Between Radioactive Iodine Treatment for Pediatric and Young Adulthood Differentiated Thyroid Cancer and Risk of Second Primary Malignancies.
Pasqual E, Schonfeld S, Morton LM, Villoing D, Lee C, Berrington de Gonzalez A, Kitahara CM
J Clin Oncol 2022 May 1;40(13):1439-1449. Epub 2022 Jan 19 doi: 10.1200/JCO.21.01841. PMID: 35044839Free PMC Article
Engineering the next generation of CAR-NK immunotherapies.
Biederstädt A, Rezvani K
Int J Hematol 2021 Nov;114(5):554-571. Epub 2021 Aug 28 doi: 10.1007/s12185-021-03209-4. PMID: 34453686Free PMC Article
The footprint of kynurenine pathway in every cancer: a new target for chemotherapy.
Ala M
Eur J Pharmacol 2021 Apr 5;896:173921. Epub 2021 Jan 30 doi: 10.1016/j.ejphar.2021.173921. PMID: 33529725
Breakthrough invasive fungal infections: Who is at risk?
Jenks JD, Cornely OA, Chen SC, Thompson GR 3rd, Hoenigl M
Mycoses 2020 Oct;63(10):1021-1032. Epub 2020 Sep 4 doi: 10.1111/myc.13148. PMID: 32744334
MDM2 inhibition: an important step forward in cancer therapy.
Konopleva M, Martinelli G, Daver N, Papayannidis C, Wei A, Higgins B, Ott M, Mascarenhas J, Andreeff M
Leukemia 2020 Nov;34(11):2858-2874. Epub 2020 Jul 10 doi: 10.1038/s41375-020-0949-z. PMID: 32651541

Prognosis

Inherited Susceptibility to Hematopoietic Malignancies in the Era of Precision Oncology.
Roloff GW, Drazer MW, Godley LA
JCO Precis Oncol 2021 Nov;5:107-122. doi: 10.1200/PO.20.00387. PMID: 34994594
The footprint of kynurenine pathway in every cancer: a new target for chemotherapy.
Ala M
Eur J Pharmacol 2021 Apr 5;896:173921. Epub 2021 Jan 30 doi: 10.1016/j.ejphar.2021.173921. PMID: 33529725
Germline predisposition in myeloid neoplasms: Unique genetic and clinical features of GATA2 deficiency and SAMD9/SAMD9L syndromes.
Sahoo SS, Kozyra EJ, Wlodarski MW
Best Pract Res Clin Haematol 2020 Sep;33(3):101197. Epub 2020 Jul 29 doi: 10.1016/j.beha.2020.101197. PMID: 33038986Free PMC Article
Heart Failure in Relation to Anthracyclines and Other Chemotherapies.
Agunbiade TA, Zaghlol RY, Barac A
Methodist Debakey Cardiovasc J 2019 Oct-Dec;15(4):243-249. doi: 10.14797/mdcj-15-4-243. PMID: 31988684Free PMC Article
Lupus and cancer.
Gayed M, Bernatsky S, Ramsey-Goldman R, Clarke A, Gordon C
Lupus 2009 May;18(6):479-85. doi: 10.1177/0961203309102556. PMID: 19395448

Clinical prediction guides

The footprint of kynurenine pathway in every cancer: a new target for chemotherapy.
Ala M
Eur J Pharmacol 2021 Apr 5;896:173921. Epub 2021 Jan 30 doi: 10.1016/j.ejphar.2021.173921. PMID: 33529725
Germline predisposition in myeloid neoplasms: Unique genetic and clinical features of GATA2 deficiency and SAMD9/SAMD9L syndromes.
Sahoo SS, Kozyra EJ, Wlodarski MW
Best Pract Res Clin Haematol 2020 Sep;33(3):101197. Epub 2020 Jul 29 doi: 10.1016/j.beha.2020.101197. PMID: 33038986Free PMC Article
Clonal hematopoiesis and risk for hematologic malignancy.
Warren JT, Link DC
Blood 2020 Oct 1;136(14):1599-1605. doi: 10.1182/blood.2019000991. PMID: 32736382Free PMC Article
Hereditary Predisposition to Hematopoietic Neoplasms: When Bloodline Matters for Blood Cancers.
Mangaonkar AA, Patnaik MM
Mayo Clin Proc 2020 Jul;95(7):1482-1498. Epub 2020 Jun 19 doi: 10.1016/j.mayocp.2019.12.013. PMID: 32571604
Therapy-related myeloid neoplasms.
Leone G, Fianchi L, Voso MT
Curr Opin Oncol 2011 Nov;23(6):672-80. doi: 10.1097/CCO.0b013e32834bcc2a. PMID: 21918440

Recent systematic reviews

Comorbidities and mortality rate in COVID-19 patients with hematological malignancies: A systematic review and meta-analysis.
Naimi A, Yashmi I, Jebeleh R, Imani Mofrad M, Azimian Abhar S, Jannesar Y, Heidary M, Pakzad R
J Clin Lab Anal 2022 May;36(5):e24387. Epub 2022 Apr 6 doi: 10.1002/jcla.24387. PMID: 35385130Free PMC Article
Risk of Atrial Fibrillation and Bleeding Diathesis Associated With Ibrutinib Treatment: A Systematic Review and Pooled Analysis of Four Randomized Controlled Trials.
Yun S, Vincelette ND, Acharya U, Abraham I
Clin Lymphoma Myeloma Leuk 2017 Jan;17(1):31-37.e13. Epub 2016 Sep 19 doi: 10.1016/j.clml.2016.09.010. PMID: 27780690
Parainfluenza virus infections in hematopoietic cell transplant recipients and hematologic malignancy patients: A systematic review.
Shah DP, Shah PK, Azzi JM, Chemaly RF
Cancer Lett 2016 Jan 28;370(2):358-64. Epub 2015 Nov 12 doi: 10.1016/j.canlet.2015.11.014. PMID: 26582658Free PMC Article

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