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Increased susceptibility to hematologic malignancies

MedGen UID:
863975
•Concept ID:
C4015538
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIncreased susceptibility to hematologic malignancies

Professional guidelines

PubMed

Clinical implementation of genetic testing in adults for hereditary hematologic malignancy syndromes.
Ansar S, Malcolmson J, Farncombe KM, Yee K, Kim RH, Sibai H
Genet Med 2022 Nov;24(11):2367-2379. Epub 2022 Sep 16 doi: 10.1016/j.gim.2022.08.010. PMID: 36112138
Association Between Radioactive Iodine Treatment for Pediatric and Young Adulthood Differentiated Thyroid Cancer and Risk of Second Primary Malignancies.
Pasqual E, Schonfeld S, Morton LM, Villoing D, Lee C, Berrington de Gonzalez A, Kitahara CM
J Clin Oncol 2022 May 1;40(13):1439-1449. Epub 2022 Jan 19 doi: 10.1200/JCO.21.01841. PMID: 35044839Free PMC Article
Practical considerations for diagnosis and management of patients and carriers.
Niemeyer CM, Mecucci C
Semin Hematol 2017 Apr;54(2):69-74. Epub 2017 Apr 6 doi: 10.1053/j.seminhematol.2017.04.002. PMID: 28637619

Recent clinical studies

Etiology

Predisposition to myeloid malignancies in Shwachman-Diamond syndrome: biological insights and clinical advances.
Reilly CR, Shimamura A
Blood 2023 Mar 30;141(13):1513-1523. doi: 10.1182/blood.2022017739. PMID: 36542827Free PMC Article
Association Between Radioactive Iodine Treatment for Pediatric and Young Adulthood Differentiated Thyroid Cancer and Risk of Second Primary Malignancies.
Pasqual E, Schonfeld S, Morton LM, Villoing D, Lee C, Berrington de Gonzalez A, Kitahara CM
J Clin Oncol 2022 May 1;40(13):1439-1449. Epub 2022 Jan 19 doi: 10.1200/JCO.21.01841. PMID: 35044839Free PMC Article
Germline predisposition in myeloid neoplasms: Unique genetic and clinical features of GATA2 deficiency and SAMD9/SAMD9L syndromes.
Sahoo SS, Kozyra EJ, Wlodarski MW
Best Pract Res Clin Haematol 2020 Sep;33(3):101197. Epub 2020 Jul 29 doi: 10.1016/j.beha.2020.101197. PMID: 33038986Free PMC Article
Breakthrough invasive fungal infections: Who is at risk?
Jenks JD, Cornely OA, Chen SC, Thompson GR 3rd, Hoenigl M
Mycoses 2020 Oct;63(10):1021-1032. Epub 2020 Sep 4 doi: 10.1111/myc.13148. PMID: 32744334
Hematologic malignancies and Li-Fraumeni syndrome.
Swaminathan M, Bannon SA, Routbort M, Naqvi K, Kadia TM, Takahashi K, Alvarado Y, Ravandi-Kashani F, Patel KP, Champlin R, Kantarjian H, Strong L, DiNardo CD
Cold Spring Harb Mol Case Stud 2019 Feb;5(1) Epub 2019 Feb 1 doi: 10.1101/mcs.a003210. PMID: 30709875Free PMC Article

Diagnosis

Predisposition to myeloid malignancies in Shwachman-Diamond syndrome: biological insights and clinical advances.
Reilly CR, Shimamura A
Blood 2023 Mar 30;141(13):1513-1523. doi: 10.1182/blood.2022017739. PMID: 36542827Free PMC Article
Engineering the next generation of CAR-NK immunotherapies.
Biederstädt A, Rezvani K
Int J Hematol 2021 Nov;114(5):554-571. Epub 2021 Aug 28 doi: 10.1007/s12185-021-03209-4. PMID: 34453686Free PMC Article
Breakthrough invasive fungal infections: Who is at risk?
Jenks JD, Cornely OA, Chen SC, Thompson GR 3rd, Hoenigl M
Mycoses 2020 Oct;63(10):1021-1032. Epub 2020 Sep 4 doi: 10.1111/myc.13148. PMID: 32744334
MDM2 inhibition: an important step forward in cancer therapy.
Konopleva M, Martinelli G, Daver N, Papayannidis C, Wei A, Higgins B, Ott M, Mascarenhas J, Andreeff M
Leukemia 2020 Nov;34(11):2858-2874. Epub 2020 Jul 10 doi: 10.1038/s41375-020-0949-z. PMID: 32651541
Hematologic malignancies and Li-Fraumeni syndrome.
Swaminathan M, Bannon SA, Routbort M, Naqvi K, Kadia TM, Takahashi K, Alvarado Y, Ravandi-Kashani F, Patel KP, Champlin R, Kantarjian H, Strong L, DiNardo CD
Cold Spring Harb Mol Case Stud 2019 Feb;5(1) Epub 2019 Feb 1 doi: 10.1101/mcs.a003210. PMID: 30709875Free PMC Article

Therapy

Association Between Radioactive Iodine Treatment for Pediatric and Young Adulthood Differentiated Thyroid Cancer and Risk of Second Primary Malignancies.
Pasqual E, Schonfeld S, Morton LM, Villoing D, Lee C, Berrington de Gonzalez A, Kitahara CM
J Clin Oncol 2022 May 1;40(13):1439-1449. Epub 2022 Jan 19 doi: 10.1200/JCO.21.01841. PMID: 35044839Free PMC Article
Engineering the next generation of CAR-NK immunotherapies.
Biederstädt A, Rezvani K
Int J Hematol 2021 Nov;114(5):554-571. Epub 2021 Aug 28 doi: 10.1007/s12185-021-03209-4. PMID: 34453686Free PMC Article
Breakthrough invasive fungal infections: Who is at risk?
Jenks JD, Cornely OA, Chen SC, Thompson GR 3rd, Hoenigl M
Mycoses 2020 Oct;63(10):1021-1032. Epub 2020 Sep 4 doi: 10.1111/myc.13148. PMID: 32744334
MDM2 inhibition: an important step forward in cancer therapy.
Konopleva M, Martinelli G, Daver N, Papayannidis C, Wei A, Higgins B, Ott M, Mascarenhas J, Andreeff M
Leukemia 2020 Nov;34(11):2858-2874. Epub 2020 Jul 10 doi: 10.1038/s41375-020-0949-z. PMID: 32651541
Achromobacter respiratory infections.
Swenson CE, Sadikot RT
Ann Am Thorac Soc 2015 Feb;12(2):252-8. doi: 10.1513/AnnalsATS.201406-288FR. PMID: 25706494

Prognosis

Inherited Susceptibility to Hematopoietic Malignancies in the Era of Precision Oncology.
Roloff GW, Drazer MW, Godley LA
JCO Precis Oncol 2021 Nov;5:107-122. doi: 10.1200/PO.20.00387. PMID: 34994594
Germline predisposition in myeloid neoplasms: Unique genetic and clinical features of GATA2 deficiency and SAMD9/SAMD9L syndromes.
Sahoo SS, Kozyra EJ, Wlodarski MW
Best Pract Res Clin Haematol 2020 Sep;33(3):101197. Epub 2020 Jul 29 doi: 10.1016/j.beha.2020.101197. PMID: 33038986Free PMC Article
Clonal hematopoiesis and risk for hematologic malignancy.
Warren JT, Link DC
Blood 2020 Oct 1;136(14):1599-1605. doi: 10.1182/blood.2019000991. PMID: 32736382Free PMC Article
Heart Failure in Relation to Anthracyclines and Other Chemotherapies.
Agunbiade TA, Zaghlol RY, Barac A
Methodist Debakey Cardiovasc J 2019 Oct-Dec;15(4):243-249. doi: 10.14797/mdcj-15-4-243. PMID: 31988684Free PMC Article
Germline Genetic Predisposition to Hematologic Malignancy.
Furutani E, Shimamura A
J Clin Oncol 2017 Mar 20;35(9):1018-1028. Epub 2017 Feb 13 doi: 10.1200/JCO.2016.70.8644. PMID: 28297620Free PMC Article

Clinical prediction guides

Prospective analysis of febrile neutropenia patients with bacteraemia: the results of an international ID-IRI study.
Erdem H, Kocoglu E, Ankarali H, El-Sokkary R, Hakamifard A, Karaali R, Kulzhanova S, El-Kholy A, Tehrani HA, Khedr R, Kaya-Kalem A, Pandak N, Cagla-Sonmezer M, Nizamuddin S, Berk-Cam H, Guner R, Elkholy JA, Llopis F, Marino A, Stebel R, Szabo BG, Belitova M, Fadel E, Yetisyigit T, Cag Y, Alkan S, Kayaaslan B, Oncu S, Ozdemir M, Yilmaz M, Isik AC, Başkol D, Sincan G, Cascio A, Ozer-Balin S, Korkmaz N, Ripon RK, Abbas S, Dumitru IM, Eser-Karlidag G, Lanzafame M, Rafey A, Raza A, Sipahi OR, Darazam IA, Elbahr U, Erdem I, Ergen P, Bilir C, Caskurlu H, Erdem A, Makek MJ, Altindis M, Lakatos B, Luca CM, Yilmaz EM, Nsutebu E, Cakmak R, Sirmatel F
Int J Antimicrob Agents 2023 Sep;62(3):106919. Epub 2023 Jul 7 doi: 10.1016/j.ijantimicag.2023.106919. PMID: 37423582
Second primary malignancies in multiple myeloma: A review.
Poh C, Keegan T, Rosenberg AS
Blood Rev 2021 Mar;46:100757. Epub 2020 Sep 6 doi: 10.1016/j.blre.2020.100757. PMID: 32972803Free PMC Article
Germline predisposition in myeloid neoplasms: Unique genetic and clinical features of GATA2 deficiency and SAMD9/SAMD9L syndromes.
Sahoo SS, Kozyra EJ, Wlodarski MW
Best Pract Res Clin Haematol 2020 Sep;33(3):101197. Epub 2020 Jul 29 doi: 10.1016/j.beha.2020.101197. PMID: 33038986Free PMC Article
Clonal hematopoiesis and risk for hematologic malignancy.
Warren JT, Link DC
Blood 2020 Oct 1;136(14):1599-1605. doi: 10.1182/blood.2019000991. PMID: 32736382Free PMC Article
Therapy-related myeloid neoplasms.
Leone G, Fianchi L, Voso MT
Curr Opin Oncol 2011 Nov;23(6):672-80. doi: 10.1097/CCO.0b013e32834bcc2a. PMID: 21918440

Recent systematic reviews

Comorbidities and mortality rate in COVID-19 patients with hematological malignancies: A systematic review and meta-analysis.
Naimi A, Yashmi I, Jebeleh R, Imani Mofrad M, Azimian Abhar S, Jannesar Y, Heidary M, Pakzad R
J Clin Lab Anal 2022 May;36(5):e24387. Epub 2022 Apr 6 doi: 10.1002/jcla.24387. PMID: 35385130Free PMC Article
Risk of Atrial Fibrillation and Bleeding Diathesis Associated With Ibrutinib Treatment: A Systematic Review and Pooled Analysis of Four Randomized Controlled Trials.
Yun S, Vincelette ND, Acharya U, Abraham I
Clin Lymphoma Myeloma Leuk 2017 Jan;17(1):31-37.e13. Epub 2016 Sep 19 doi: 10.1016/j.clml.2016.09.010. PMID: 27780690
Parainfluenza virus infections in hematopoietic cell transplant recipients and hematologic malignancy patients: A systematic review.
Shah DP, Shah PK, Azzi JM, Chemaly RF
Cancer Lett 2016 Jan 28;370(2):358-64. Epub 2015 Nov 12 doi: 10.1016/j.canlet.2015.11.014. PMID: 26582658Free PMC Article

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