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J wave

MedGen UID:
866319
Concept ID:
C4018858
Finding
Synonyms: EKG J waves; Osborne waves
 
HPO: HP:0012272

Definition

The J wave is a positive convex deflection that occurs at the junction of the QRS complex and ST segment, the J-point. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVJ wave

Conditions with this feature

Brugada syndrome 3
MedGen UID:
395633
Concept ID:
C2678478
Disease or Syndrome
Brugada syndrome is characterized by cardiac conduction abnormalities (ST segment abnormalities in leads V1-V3 on EKG and a high risk for ventricular arrhythmias) that can result in sudden death. Brugada syndrome presents primarily during adulthood, although age at diagnosis may range from infancy to late adulthood. The mean age of sudden death is approximately 40 years. Clinical presentations may also include sudden infant death syndrome (SIDS; death of a child during the first year of life without an identifiable cause) and sudden unexpected nocturnal death syndrome (SUNDS), a typical presentation in individuals from Southeast Asia. Other conduction defects can include first-degree AV block, intraventricular conduction delay, right bundle branch block, and sick sinus syndrome.

Professional guidelines

PubMed

Madaloso BA, Samesima N, Tobias NMMO, Tavares CAM, Pereira Filho HG, Facin ME, Pastore CA
J Electrocardiol 2022 May-Jun;72:131-137. Epub 2022 Mar 30 doi: 10.1016/j.jelectrocard.2022.03.008. PMID: 35512492
Argenziano M, Antzelevitch C
Expert Rev Cardiovasc Ther 2018 Jun;16(6):387-404. Epub 2018 May 18 doi: 10.1080/14779072.2018.1475230. PMID: 29757020Free PMC Article
Riera AR, Uchida AH, Schapachnik E, Dubner S, Zhang L, Celso Ferreira Filho, Ferreira C
Cardiol J 2008;15(1):4-16. PMID: 18651379

Recent clinical studies

Etiology

Di Diego JM, Antzelevitch C
Pacing Clin Electrophysiol 2018 Jul;41(7):684-699. Epub 2018 Jun 30 doi: 10.1111/pace.13408. PMID: 29870068Free PMC Article
Priori SG, Napolitano C
Card Electrophysiol Clin 2018 Jun;10(2):355-369. doi: 10.1016/j.ccep.2018.02.009. PMID: 29784488
Antzelevitch C, Yan GX
Heart Rhythm 2015 Aug;12(8):1852-66. Epub 2015 Apr 11 doi: 10.1016/j.hrthm.2015.04.014. PMID: 25869754Free PMC Article
Li GL, Yang L, Cui CC, Sun CF, Yan GX
Chin Med J (Engl) 2015 Apr 5;128(7):969-75. doi: 10.4103/0366-6999.154320. PMID: 25836620Free PMC Article
Antzelevitch C, Yan GX
Heart Rhythm 2010 Apr;7(4):549-58. Epub 2009 Dec 11 doi: 10.1016/j.hrthm.2009.12.006. PMID: 20153265Free PMC Article

Diagnosis

Miles C, Boukens BJ, Scrocco C, Wilde AAM, Nademanee K, Haissaguerre M, Coronel R, Behr ER
Circulation 2023 May 23;147(21):1622-1633. Epub 2023 May 22 doi: 10.1161/CIRCULATIONAHA.122.061924. PMID: 37216437
Antzelevitch C, Di Diego JM
Trends Cardiovasc Med 2022 Aug;32(6):350-363. Epub 2021 Jul 10 doi: 10.1016/j.tcm.2021.07.001. PMID: 34256120Free PMC Article
Priori SG, Napolitano C
Card Electrophysiol Clin 2018 Jun;10(2):355-369. doi: 10.1016/j.ccep.2018.02.009. PMID: 29784488
Froelicher V, Wagner G
J Electrocardiol 2013 Sep-Oct;46(5):381-2. doi: 10.1016/j.jelectrocard.2013.06.030. PMID: 23981303
Antzelevitch C, Yan GX
Heart Rhythm 2010 Apr;7(4):549-58. Epub 2009 Dec 11 doi: 10.1016/j.hrthm.2009.12.006. PMID: 20153265Free PMC Article

Therapy

Aizawa Y, Ohashi N, Kawamura A, Ogawa S, Aizawa Y
Pacing Clin Electrophysiol 2023 Aug;46(8):868-874. Epub 2023 Jul 18 doi: 10.1111/pace.14787. PMID: 37461879
Di Diego JM, Barajas-Martinez H, Cox R, Robinson VM, Jung J, Fouda M, Patocskai B, Abdelsayed M, Ruben PC, Antzelevitch C
PLoS One 2023;18(5):e0281977. Epub 2023 May 9 doi: 10.1371/journal.pone.0281977. PMID: 37159454Free PMC Article
Argenziano M, Antzelevitch C
Expert Rev Cardiovasc Ther 2018 Jun;16(6):387-404. Epub 2018 May 18 doi: 10.1080/14779072.2018.1475230. PMID: 29757020Free PMC Article
Huikuri HV, Juhani Junttila M
Trends Cardiovasc Med 2015 Jan;25(1):24-30. Epub 2014 Sep 6 doi: 10.1016/j.tcm.2014.08.008. PMID: 25442737
Shen MJ, Zipes DP
Circ Res 2014 Mar 14;114(6):1004-21. doi: 10.1161/CIRCRESAHA.113.302549. PMID: 24625726

Prognosis

Kamakura T, Shinohara T, Yodogawa K, Murakoshi N, Morita H, Takahashi N, Inden Y, Shimizu W, Nogami A, Horie M, Aiba T, Kusano K
Heart 2020 Feb;106(4):299-306. Epub 2019 Aug 7 doi: 10.1136/heartjnl-2019-315007. PMID: 31391205
Priori SG, Napolitano C
Card Electrophysiol Clin 2018 Jun;10(2):355-369. doi: 10.1016/j.ccep.2018.02.009. PMID: 29784488
Omar HR
Herz 2016 Feb;41(1):48-56. Epub 2015 Aug 14 doi: 10.1007/s00059-015-4338-8. PMID: 26272271
Pelliccia A, Quattrini FM
J Electrocardiol 2015 May-Jun;48(3):385-9. Epub 2015 Mar 12 doi: 10.1016/j.jelectrocard.2015.03.012. PMID: 25796101
Junttila MJ, Sager SJ, Tikkanen JT, Anttonen O, Huikuri HV, Myerburg RJ
Eur Heart J 2012 Nov;33(21):2639-43. Epub 2012 May 29 doi: 10.1093/eurheartj/ehs110. PMID: 22645193

Clinical prediction guides

Aizawa Y, Ohashi N, Kawamura A, Ogawa S, Aizawa Y
Pacing Clin Electrophysiol 2023 Aug;46(8):868-874. Epub 2023 Jul 18 doi: 10.1111/pace.14787. PMID: 37461879
Wu CI, Chang SL, Lin CY, Vicera JJB, Lin YJ, Lo LW, Chung FP, Hu YF, Chang TY, Chao TF, Liao JN, Tuan TC, Liu CM, Te ALD, Chen SA
J Cardiol 2019 May;73(5):351-357. Epub 2018 Dec 28 doi: 10.1016/j.jjcc.2018.11.005. PMID: 30595403
Omar HR
Herz 2016 Feb;41(1):48-56. Epub 2015 Aug 14 doi: 10.1007/s00059-015-4338-8. PMID: 26272271
Junttila MJ, Sager SJ, Tikkanen JT, Anttonen O, Huikuri HV, Myerburg RJ
Eur Heart J 2012 Nov;33(21):2639-43. Epub 2012 May 29 doi: 10.1093/eurheartj/ehs110. PMID: 22645193
Lévy S, Sbragia P
J Interv Card Electrophysiol 2011 Dec;32(3):181-6. Epub 2011 Jul 21 doi: 10.1007/s10840-011-9597-6. PMID: 21833514

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