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Advanced ossification of the hand bones

MedGen UID:
866538
•Concept ID:
C4020834
•
Finding
Synonyms: Accelerated maturation of hand bones; Advanced maturation of the hand bones
 
HPO: HP:0004051

Definition

Ossification of hand bones at an earlier age than normal. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdvanced ossification of the hand bones

Recent clinical studies

Etiology

Applicability of the Calcaneal Apophysis Ossification Staging System to the Modern Pediatric Population.
Li SQ, Nicholson AD, Cooperman DR, Liu RW
J Pediatr Orthop 2019 Jan;39(1):46-50. doi: 10.1097/BPO.0000000000001058. PMID: 29166293
A cross-sectional study on the skeletal development of the hand and wrist from preadolescence to early adulthood among Chinese in Taiwan.
Chang HF, Wu KM, Chen KC
Zhonghua Ya Yi Xue Hui Za Zhi 1990 Mar;9(1):1-11. PMID: 2131157

Therapy

IV. skeletal development from birth to 7 years.
Taranger J, Bruning B, Claesson I, Karlberg P, Landström T, Lindström B
Acta Paediatr Scand Suppl 1976;(258):98-108. doi: 10.1111/j.1651-2227.1976.tb14764.x. PMID: 183457

Clinical prediction guides

A variant of Desbuquois dysplasia characterized by advanced carpal bone age, short metacarpals, and elongated phalanges: report of seven cases.
Kim OH, Nishimura G, Song HR, Matsui Y, Sakazume S, Yamada M, Narumi Y, Alanay Y, Unger S, Cho TJ, Park SS, Ikegawa S, Meinecke P, Superti-Furga A
Am J Med Genet A 2010 Apr;152A(4):875-85. doi: 10.1002/ajmg.a.33347. PMID: 20358597

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