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Cerebral hyaline bodies

MedGen UID:
866674
Concept ID:
C4021021
Anatomical Abnormality
Synonym: Cerebral colloid bodies
 
HPO: HP:0100319

Definition

Cerebral eosinophilic, discrete, intracytoplasmatic inclusions of unknown significance. [from HPO]

Term Hierarchy

Recent clinical studies

Etiology

Paradela RS, Justo AFO, Paes VR, Leite REP, Pasqualucci CA, Grinberg LT, Naslavsky MS, Zatz M, Nitrini R, Jacob-Filho W, Suemoto CK
Acta Neuropathol Commun 2023 Dec 19;11(1):205. doi: 10.1186/s40478-023-01681-z. PMID: 38115150Free PMC Article
Yu WY, Xu Z, Lee HY, Tokumaru A, Tan JMM, Ng A, Murayama S, Lim CCT
Neuroradiology 2019 Nov;61(11):1281-1290. Epub 2019 Jul 11 doi: 10.1007/s00234-019-02257-2. PMID: 31292692
Sone J, Mori K, Inagaki T, Katsumata R, Takagi S, Yokoi S, Araki K, Kato T, Nakamura T, Koike H, Takashima H, Hashiguchi A, Kohno Y, Kurashige T, Kuriyama M, Takiyama Y, Tsuchiya M, Kitagawa N, Kawamoto M, Yoshimura H, Suto Y, Nakayasu H, Uehara N, Sugiyama H, Takahashi M, Kokubun N, Konno T, Katsuno M, Tanaka F, Iwasaki Y, Yoshida M, Sobue G
Brain 2016 Dec;139(Pt 12):3170-3186. Epub 2016 Oct 25 doi: 10.1093/brain/aww249. PMID: 27797808Free PMC Article
Ince PG, Lowe J, Shaw PJ
Neuropathol Appl Neurobiol 1998 Apr;24(2):104-17. doi: 10.1046/j.1365-2990.1998.00108.x. PMID: 9634206
Liberski PP, Kordek R
Ultrastruct Pathol 1997 Jan-Feb;21(1):1-31. doi: 10.3109/01913129709023244. PMID: 9029763

Diagnosis

Sone J, Mitsuhashi S, Fujita A, Mizuguchi T, Hamanaka K, Mori K, Koike H, Hashiguchi A, Takashima H, Sugiyama H, Kohno Y, Takiyama Y, Maeda K, Doi H, Koyano S, Takeuchi H, Kawamoto M, Kohara N, Ando T, Ieda T, Kita Y, Kokubun N, Tsuboi Y, Katoh K, Kino Y, Katsuno M, Iwasaki Y, Yoshida M, Tanaka F, Suzuki IK, Frith MC, Matsumoto N, Sobue G
Nat Genet 2019 Aug;51(8):1215-1221. Epub 2019 Jul 22 doi: 10.1038/s41588-019-0459-y. PMID: 31332381
Suemoto CK, Ferretti-Rebustini RE, Rodriguez RD, Leite RE, Soterio L, Brucki SM, Spera RR, Cippiciani TM, Farfel JM, Chiavegatto Filho A, Naslavsky MS, Zatz M, Pasqualucci CA, Jacob-Filho W, Nitrini R, Grinberg LT
PLoS Med 2017 Mar;14(3):e1002267. Epub 2017 Mar 28 doi: 10.1371/journal.pmed.1002267. PMID: 28350821Free PMC Article
Sone J, Mori K, Inagaki T, Katsumata R, Takagi S, Yokoi S, Araki K, Kato T, Nakamura T, Koike H, Takashima H, Hashiguchi A, Kohno Y, Kurashige T, Kuriyama M, Takiyama Y, Tsuchiya M, Kitagawa N, Kawamoto M, Yoshimura H, Suto Y, Nakayasu H, Uehara N, Sugiyama H, Takahashi M, Kokubun N, Konno T, Katsuno M, Tanaka F, Iwasaki Y, Yoshida M, Sobue G
Brain 2016 Dec;139(Pt 12):3170-3186. Epub 2016 Oct 25 doi: 10.1093/brain/aww249. PMID: 27797808Free PMC Article
Takahashi-Fujigasaki J, Nakano Y, Uchino A, Murayama S
Geriatr Gerontol Int 2016 Mar;16 Suppl 1:51-6. doi: 10.1111/ggi.12725. PMID: 27018283
Perez MT, Farkas J, Padron S, Changus JE, Webster EL
Ann Diagn Pathol 2004 Jun;8(3):142-50. doi: 10.1016/j.anndiagpath.2004.03.006. PMID: 15185261

Therapy

Schlaen A, Ingolotti M, Couto C, Jacob N, Pineda G, Saravia M
Eur J Ophthalmol 2015 May 25;25(4):e53-5. doi: 10.5301/ejo.5000550. PMID: 25612657
Wong JC, O'Neill B, Hawkins CE, Kleinschmidt-DeMasters BK, Hazrati LN
Neurology 2013 Jul 16;81(3):e14-6. doi: 10.1212/WNL.0b013e31829bfe54. PMID: 23858415Free PMC Article
Wakayama I, Nerurkar VR, Strong MJ, Garruto RM
Acta Neuropathol 1996 Dec;92(6):545-54. doi: 10.1007/s004010050560. PMID: 8960311
Rihs JD, Padhye AA, Good CB
J Clin Microbiol 1996 Jul;34(7):1628-32. doi: 10.1128/JCM.34.7.1628-1632.1996. PMID: 8784558Free PMC Article
Sasaki S, Maruyama S
Acta Neuropathol 1991;82(4):295-301. doi: 10.1007/BF00308815. PMID: 1722068

Prognosis

Takahashi-Fujigasaki J, Nakano Y, Uchino A, Murayama S
Geriatr Gerontol Int 2016 Mar;16 Suppl 1:51-6. doi: 10.1111/ggi.12725. PMID: 27018283
Williams SR, Joos BW, Parker JC, Parker JR
Ann Clin Lab Sci 2008 Summer;38(3):287-92. PMID: 18715860
Perry A, Scheithauer BW, Stafford SL, Abell-Aleff PC, Meyer FB
Am J Surg Pathol 1998 Dec;22(12):1482-90. doi: 10.1097/00000478-199812000-00005. PMID: 9850174
Liberski PP, Kordek R
Ultrastruct Pathol 1997 Jan-Feb;21(1):1-31. doi: 10.3109/01913129709023244. PMID: 9029763
Sloane AE, Becker LE, Ang LC, Wark J, Haslam RH
Pediatr Neurol 1994 Feb;10(1):61-6. doi: 10.1016/0887-8994(94)90070-1. PMID: 7515242

Clinical prediction guides

Wang R, Nie X, Xu S, Zhang M, Dong Z, Yu S
Headache 2020 Feb;60(2):382-395. Epub 2019 Nov 8 doi: 10.1111/head.13687. PMID: 31701545
Sone J, Mitsuhashi S, Fujita A, Mizuguchi T, Hamanaka K, Mori K, Koike H, Hashiguchi A, Takashima H, Sugiyama H, Kohno Y, Takiyama Y, Maeda K, Doi H, Koyano S, Takeuchi H, Kawamoto M, Kohara N, Ando T, Ieda T, Kita Y, Kokubun N, Tsuboi Y, Katoh K, Kino Y, Katsuno M, Iwasaki Y, Yoshida M, Tanaka F, Suzuki IK, Frith MC, Matsumoto N, Sobue G
Nat Genet 2019 Aug;51(8):1215-1221. Epub 2019 Jul 22 doi: 10.1038/s41588-019-0459-y. PMID: 31332381
Sone J, Mori K, Inagaki T, Katsumata R, Takagi S, Yokoi S, Araki K, Kato T, Nakamura T, Koike H, Takashima H, Hashiguchi A, Kohno Y, Kurashige T, Kuriyama M, Takiyama Y, Tsuchiya M, Kitagawa N, Kawamoto M, Yoshimura H, Suto Y, Nakayasu H, Uehara N, Sugiyama H, Takahashi M, Kokubun N, Konno T, Katsuno M, Tanaka F, Iwasaki Y, Yoshida M, Sobue G
Brain 2016 Dec;139(Pt 12):3170-3186. Epub 2016 Oct 25 doi: 10.1093/brain/aww249. PMID: 27797808Free PMC Article
Takahashi-Fujigasaki J, Nakano Y, Uchino A, Murayama S
Geriatr Gerontol Int 2016 Mar;16 Suppl 1:51-6. doi: 10.1111/ggi.12725. PMID: 27018283
Liberski PP, Kordek R
Ultrastruct Pathol 1997 Jan-Feb;21(1):1-31. doi: 10.3109/01913129709023244. PMID: 9029763

Recent systematic reviews

Wang R, Nie X, Xu S, Zhang M, Dong Z, Yu S
Headache 2020 Feb;60(2):382-395. Epub 2019 Nov 8 doi: 10.1111/head.13687. PMID: 31701545

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