Hyperplastic labia majora

MedGen UID:: 866713
•Concept ID:: C4021060
•: Anatomical Abnormality

Synonyms:	Enlarged labia majora; Hyperplasia of labia majora

HPO:	HP:0012882

Definition

Overgrowth of the outer labia. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVHyperplastic labia majora

Abnormality of the genital system
- Abnormal reproductive system morphology
  - Abnormality of the female genitalia
    - Abnormal female external genitalia morphology
      - Abnormal labia morphology
        Abnormal labia majora morphology
        Hyperplastic labia majora

Recent clinical studies

Therapy

Congenital adrenal hyperplasia: Results of medical therapy on appearance of external genitalia.

Kulshreshtha B, Khadgawat R, Eunice M, Ammini AC
J Pediatr Urol 2010 Dec;6(6):555-9. Epub 2010 Feb 8 doi: 10.1016/j.jpurol.2010.01.001. PMID: 20117057

Systemic contact dermatitis to copper-containing IUD.

Purello D'Ambrosio F, Ricciardi L, Isola S, Gangemi S, Cilia M, Levanti C, Marcazzò A
Allergy 1996 Sep;51(9):658-9. doi: 10.1111/j.1398-9995.1996.tb04688.x. PMID: 8899120

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Prognosis

Passerini-glazel feminizing genitoplasty: modifications in 17 years of experience with 82 cases.

Lesma A, Bocciardi A, Montorsi F, Rigatti P
Eur Urol 2007 Dec;52(6):1638-44. Epub 2007 Mar 20 doi: 10.1016/j.eururo.2007.02.068. PMID: 17408848

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Clinical prediction guides

Adenoid cystic carcinoma of the Bartholin's gland is easily misdiagnosed: A case report and literature review.

Wang W, Chen H, Guo H, Chen L, Zhu M, Zhu Y
Medicine (Baltimore) 2022 Nov 11;101(45):e31744. doi: 10.1097/MD.0000000000031744. PMID: 36397326 Free PMC Article

45 years' experience with early childhood anatomical technique of feminising genitoplasty for 46 XX Congenital Adrenal Hyperplasia -observations of vaginal introital anatomy and its relationship to the perineal body.

Hennayake S, Barnes A, Mariotto A, Goyal A, Ajao A, Cserni T, Busby G, Patel L, Skae M, Nicholson J, Bianchi A
J Pediatr Urol 2022 Oct;18(5):611.e1-611.e8. Epub 2022 Jul 19 doi: 10.1016/j.jpurol.2022.07.007. PMID: 35970739

Acquired lymphangiectasia: a rare mimic of genital warts.

Simeonovski V, Kostovski M, Gjoric I, Damevska S, Igor P
Dermatol Online J 2020 Dec 15;26(12) PMID: 33423429

1-Stage feminizing genitoplasty: 8 years of experience with 49 cases.

Farkas A, Chertin B, Hadas-Halpren I
J Urol 2001 Jun;165(6 Pt 2):2341-6. doi: 10.1016/S0022-5347(05)66199-X. PMID: 11371974

Acantholytic dermatosis localized to the vulvocrural area.

Cooper PH
J Cutan Pathol 1989 Apr;16(2):81-4. doi: 10.1111/j.1600-0560.1989.tb00015.x. PMID: 2760291

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