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Testicular fibrosis

MedGen UID:
866714
Concept ID:
C4021061
Pathologic Function
Synonyms: Fibrotic testes; Fibrotic testicle
 
HPO: HP:0012860

Definition

Formation of excess connective tissue in the testicle. [from HPO]

Professional guidelines

PubMed

Gies I, Unuane D, Velkeniers B, De Schepper J
Eur J Endocrinol 2014 Aug;171(2):R67-77. Epub 2014 May 6 doi: 10.1530/EJE-14-0213. PMID: 24801585

Recent clinical studies

Etiology

Willems M, Olsen C, Caljon B, Vloeberghs V, De Schepper J, Tournaye H, Van Saen D, Goossens E
Sci Rep 2022 Dec 13;12(1):21518. doi: 10.1038/s41598-022-26011-6. PMID: 36513788Free PMC Article
Willems M, Seβenhausen P, Gies I, Vloeberghs V, Tournaye H, Van Saen D, Goossens E
Reprod Biomed Online 2022 May;44(5):896-906. Epub 2022 Jan 31 doi: 10.1016/j.rbmo.2022.01.009. PMID: 35282995
Willems M, Vloeberghs V, Gies I, De Schepper J, Tournaye H, Goossens E, Van Saen D
Hum Reprod 2020 Aug 1;35(8):1753-1764. doi: 10.1093/humrep/deaa132. PMID: 32649748
Roy C, de Marini P, Labani A, Leyendecker P, Ohana M
Clin Radiol 2020 Jul;75(7):560.e9-560.e17. Epub 2020 Apr 2 doi: 10.1016/j.crad.2020.02.016. PMID: 32248949
Kauerhof AC, Nicolas N, Bhushan S, Wahle E, Loveland KA, Fietz D, Bergmann M, Groome NP, Kliesch S, Schuppe HC, Pilatz A, Meinhardt A, Hedger MP, Fijak M
Hum Reprod 2019 Aug 1;34(8):1536-1550. doi: 10.1093/humrep/dez109. PMID: 31340036

Diagnosis

Willems M, Gies I, Van Saen D
Am J Med Genet C Semin Med Genet 2020 Jun;184(2):356-370. Epub 2020 May 15 doi: 10.1002/ajmg.c.31787. PMID: 32412180
Roy C, de Marini P, Labani A, Leyendecker P, Ohana M
Clin Radiol 2020 Jul;75(7):560.e9-560.e17. Epub 2020 Apr 2 doi: 10.1016/j.crad.2020.02.016. PMID: 32248949
Gies I, Unuane D, Velkeniers B, De Schepper J
Eur J Endocrinol 2014 Aug;171(2):R67-77. Epub 2014 May 6 doi: 10.1530/EJE-14-0213. PMID: 24801585
Velasco G, Savarese V, Sandorfi N, Jimenez SA, Jabbour S
Endocr Pract 2011 Jan-Feb;17(1):95-8. doi: 10.4158/EP10184.CR. PMID: 20841307
Tasian GE, Hittelman AB, Kim GE, DiSandro MJ, Baskin LS
J Urol 2009 Aug;182(2):704-9. Epub 2009 Jun 17 doi: 10.1016/j.juro.2009.04.032. PMID: 19539332

Therapy

Gies I, Unuane D, Velkeniers B, De Schepper J
Eur J Endocrinol 2014 Aug;171(2):R67-77. Epub 2014 May 6 doi: 10.1530/EJE-14-0213. PMID: 24801585
Darke S, Torok M, Duflou J
J Forensic Sci 2014 Jul;59(4):1025-8. Epub 2014 Feb 19 doi: 10.1111/1556-4029.12424. PMID: 24611438
Sahreen S, Khan MR, Khan RA, Shah NA
Lipids Health Dis 2013 Jun 20;12:90. doi: 10.1186/1476-511X-12-90. PMID: 23786717Free PMC Article
Velasco G, Savarese V, Sandorfi N, Jimenez SA, Jabbour S
Endocr Pract 2011 Jan-Feb;17(1):95-8. doi: 10.4158/EP10184.CR. PMID: 20841307
Hoffman WH, Kovacs KT, Gala RR, Keel BA, Jarrell TS, Ellegood JO, Burek CL
J Endocrinol Invest 1991 Jul-Aug;14(7):609-16. doi: 10.1007/BF03346881. PMID: 1940067

Prognosis

Deebel NA, Galdon G, Zarandi NP, Stogner-Underwood K, Howards S, Lovato J, Kogan S, Atala A, Lue Y, Sadri-Ardekani H
Hum Reprod Update 2020 Jan 1;26(1):58-72. doi: 10.1093/humupd/dmz038. PMID: 31822886
Mechlin CW, Levesque J, Feustel P, Kogan BA
J Pediatr Urol 2014 Jun;10(3):527-31. Epub 2013 Dec 25 doi: 10.1016/j.jpurol.2013.11.014. PMID: 24406204
Tasian GE, Hittelman AB, Kim GE, DiSandro MJ, Baskin LS
J Urol 2009 Aug;182(2):704-9. Epub 2009 Jun 17 doi: 10.1016/j.juro.2009.04.032. PMID: 19539332

Clinical prediction guides

Peng W, Kepsch A, Kracht TO, Hasan H, Wijayarathna R, Wahle E, Pleuger C, Bhushan S, Günther S, Kauerhof AC, Planinić A, Fietz D, Schuppe HC, Wygrecka M, Loveland KL, Ježek D, Meinhardt A, Hedger MP, Fijak M
Cell Mol Life Sci 2022 Nov 24;79(12):602. doi: 10.1007/s00018-022-04632-4. PMID: 36434305Free PMC Article
Willems M, Seβenhausen P, Gies I, Vloeberghs V, Tournaye H, Van Saen D, Goossens E
Reprod Biomed Online 2022 May;44(5):896-906. Epub 2022 Jan 31 doi: 10.1016/j.rbmo.2022.01.009. PMID: 35282995
Willems M, Vloeberghs V, Gies I, De Schepper J, Tournaye H, Goossens E, Van Saen D
Hum Reprod 2020 Aug 1;35(8):1753-1764. doi: 10.1093/humrep/deaa132. PMID: 32649748
Willems M, Gies I, Van Saen D
Am J Med Genet C Semin Med Genet 2020 Jun;184(2):356-370. Epub 2020 May 15 doi: 10.1002/ajmg.c.31787. PMID: 32412180
Tasian GE, Hittelman AB, Kim GE, DiSandro MJ, Baskin LS
J Urol 2009 Aug;182(2):704-9. Epub 2009 Jun 17 doi: 10.1016/j.juro.2009.04.032. PMID: 19539332

Recent systematic reviews

Bradshaw AW, Deebel NA, Xu MC, Kogan S, Atala A, Sadri-Ardekani H
Andrology 2023 Mar;11(3):435-443. Epub 2022 Oct 27 doi: 10.1111/andr.13327. PMID: 36252136
Deebel NA, Galdon G, Zarandi NP, Stogner-Underwood K, Howards S, Lovato J, Kogan S, Atala A, Lue Y, Sadri-Ardekani H
Hum Reprod Update 2020 Jan 1;26(1):58-72. doi: 10.1093/humupd/dmz038. PMID: 31822886

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