U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Generalized opacification of the cornea

MedGen UID:
866795
Concept ID:
C4021147
Anatomical Abnormality
Synonym: Generalised opacification of the cornea
 
HPO: HP:0011494

Definition

Generalized reduced transparency of the stroma of the cornea. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Generalized opacification of the cornea

Professional guidelines

PubMed

Jawaheer L, Anijeet D, Ramaesh K
Surv Ophthalmol 2017 Jul-Aug;62(4):522-532. Epub 2016 Nov 14 doi: 10.1016/j.survophthal.2016.11.003. PMID: 27856177
Ramona BI, Catalina C, Andrei M, Daciana S, Calin T
Rom J Ophthalmol 2016 Jan-Mar;60(1):28-30. PMID: 27220229Free PMC Article
Amon M
Nepal J Ophthalmol 2011 Jan-Jun;3(1):3-8. doi: 10.3126/nepjoph.v3i1.4270. PMID: 21505539

Recent clinical studies

Etiology

Riedl JC, Misirkhanova A, Wasielica-Poslednik J, Schuster AK, Schmidtmann I, Beutel ME, Pfeiffer N, Gericke A
Acta Ophthalmol 2024 Sep;102(6):e956-e960. Epub 2024 Mar 27 doi: 10.1111/aos.16680. PMID: 38536709
Chameettachal S, Venuganti A, Parekh Y, Prasad D, Joshi VP, Vashishtha A, Basu S, Singh V, Bokara KK, Pati F
Acta Biomater 2023 Nov;171:289-307. Epub 2023 Sep 7 doi: 10.1016/j.actbio.2023.09.002. PMID: 37683964
Salik I, Gupta A, Tara A, Zaidman G, Barst S
Paediatr Anaesth 2020 May;30(5):577-583. Epub 2020 Mar 16 doi: 10.1111/pan.13843. PMID: 32107814
Lin HY, Chan WC, Chen LJ, Lee YC, Yeh SI, Niu DM, Chiu PC, Tsai WH, Hwu WL, Chuang CK, Lin SP
Mol Genet Genomic Med 2019 May;7(5):e00617. Epub 2019 Mar 8 doi: 10.1002/mgg3.617. PMID: 30848093Free PMC Article
Krumeich JH, Daniel J, Knülle A
J Cataract Refract Surg 1998 Apr;24(4):456-63. doi: 10.1016/s0886-3350(98)80284-8. PMID: 9584238

Diagnosis

Riedl JC, Misirkhanova A, Wasielica-Poslednik J, Schuster AK, Schmidtmann I, Beutel ME, Pfeiffer N, Gericke A
Acta Ophthalmol 2024 Sep;102(6):e956-e960. Epub 2024 Mar 27 doi: 10.1111/aos.16680. PMID: 38536709
Williams D, Chung DD, Hovakimyan A, Davtyan A, Glasgow BJ, Aldave AJ
Cornea 2023 Apr 1;42(4):464-469. Epub 2022 Dec 19 doi: 10.1097/ICO.0000000000003167. PMID: 36534610
Lin HY, Chan WC, Chen LJ, Lee YC, Yeh SI, Niu DM, Chiu PC, Tsai WH, Hwu WL, Chuang CK, Lin SP
Mol Genet Genomic Med 2019 May;7(5):e00617. Epub 2019 Mar 8 doi: 10.1002/mgg3.617. PMID: 30848093Free PMC Article
Hossain P, Tourkmani AK, Kazakos D, Jones M, Anderson D; NHS Blood and Transplant Ocular Tissue Advisory Group and Contributing Ophthalmologists
Br J Ophthalmol 2018 Jan;102(1):26-30. Epub 2017 May 11 doi: 10.1136/bjophthalmol-2016-309870. PMID: 28495906
Jawaheer L, Anijeet D, Ramaesh K
Surv Ophthalmol 2017 Jul-Aug;62(4):522-532. Epub 2016 Nov 14 doi: 10.1016/j.survophthal.2016.11.003. PMID: 27856177

Therapy

Riedl JC, Misirkhanova A, Wasielica-Poslednik J, Schuster AK, Schmidtmann I, Beutel ME, Pfeiffer N, Gericke A
Acta Ophthalmol 2024 Sep;102(6):e956-e960. Epub 2024 Mar 27 doi: 10.1111/aos.16680. PMID: 38536709
Kumar R, Sinha NR, Mohan RR
Ocul Surf 2023 Jul;29:279-297. Epub 2023 May 25 doi: 10.1016/j.jtos.2023.05.007. PMID: 37244594
Vrijman V, van der Linden JW, van der Meulen IJE, Mourits MP, Lapid-Gortzak R
J Cataract Refract Surg 2018 Apr;44(4):466-470. Epub 2018 Apr 22 doi: 10.1016/j.jcrs.2018.01.030. PMID: 29685778
Ramona BI, Catalina C, Andrei M, Daciana S, Calin T
Rom J Ophthalmol 2016 Jan-Mar;60(1):28-30. PMID: 27220229Free PMC Article
García García GP, Martínez JB
Cornea 2008 Oct;27(9):980-7. doi: 10.1097/ICO.0b013e31817618d7. PMID: 18812758

Prognosis

Williams D, Chung DD, Hovakimyan A, Davtyan A, Glasgow BJ, Aldave AJ
Cornea 2023 Apr 1;42(4):464-469. Epub 2022 Dec 19 doi: 10.1097/ICO.0000000000003167. PMID: 36534610
Zhang BN, Chan TCY, Tam POS, Liu Y, Pang CP, Jhanji V, Chen LJ, Chu WK
Dis Markers 2019;2019:8781524. Epub 2019 Nov 12 doi: 10.1155/2019/8781524. PMID: 31781308Free PMC Article
Vrijman V, van der Linden JW, van der Meulen IJE, Mourits MP, Lapid-Gortzak R
J Cataract Refract Surg 2018 Apr;44(4):466-470. Epub 2018 Apr 22 doi: 10.1016/j.jcrs.2018.01.030. PMID: 29685778
Hossain P, Tourkmani AK, Kazakos D, Jones M, Anderson D; NHS Blood and Transplant Ocular Tissue Advisory Group and Contributing Ophthalmologists
Br J Ophthalmol 2018 Jan;102(1):26-30. Epub 2017 May 11 doi: 10.1136/bjophthalmol-2016-309870. PMID: 28495906
Krumeich JH, Daniel J, Knülle A
J Cataract Refract Surg 1998 Apr;24(4):456-63. doi: 10.1016/s0886-3350(98)80284-8. PMID: 9584238

Clinical prediction guides

Williams D, Chung DD, Hovakimyan A, Davtyan A, Glasgow BJ, Aldave AJ
Cornea 2023 Apr 1;42(4):464-469. Epub 2022 Dec 19 doi: 10.1097/ICO.0000000000003167. PMID: 36534610
Zhang BN, Chan TCY, Tam POS, Liu Y, Pang CP, Jhanji V, Chen LJ, Chu WK
Dis Markers 2019;2019:8781524. Epub 2019 Nov 12 doi: 10.1155/2019/8781524. PMID: 31781308Free PMC Article
Santos-Bueso E
Arch Soc Esp Oftalmol (Engl Ed) 2019 Oct;94(10):471-477. Epub 2019 Aug 1 doi: 10.1016/j.oftal.2019.06.006. PMID: 31378388
Kivelä T, Uusitalo M
Prog Retin Eye Res 1998 Jul;17(3):385-428. doi: 10.1016/s1350-9462(98)00001-9. PMID: 9695798
Krumeich JH, Daniel J, Knülle A
J Cataract Refract Surg 1998 Apr;24(4):456-63. doi: 10.1016/s0886-3350(98)80284-8. PMID: 9584238

Recent systematic reviews

Jawaheer L, Anijeet D, Ramaesh K
Surv Ophthalmol 2017 Jul-Aug;62(4):522-532. Epub 2016 Nov 14 doi: 10.1016/j.survophthal.2016.11.003. PMID: 27856177

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...