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Abnormality of somatosensory evoked potentials

MedGen UID:
867219
Concept ID:
C4021577
Anatomical Abnormality
Synonym: Abnormality of SSEPs
 
HPO: HP:0007377

Definition

An abnormality of somatosensory evoked potentials (SSEP), i.e., of the electrical signals of sensation going from the body to the brain in response to a defined stimulus. Recording electrodes are placed over the scalp, spine, and peripheral nerves proximal to the stimulation site. Clinical studies generally use electrical stimulation of peripheral nerves to elicit potentials. SSEP testing determines whether peripheral sensory nerves are able to transmit sensory information like pain, temperature, and touch to the brain. Abnormal SSEPs can result from dysfunction at the level of the peripheral nerve, plexus, spinal root, spinal cord, brain stem, thalamocortical projections, or primary somatosensory cortex. [from HPO]

Professional guidelines

PubMed

Garcia-Larrea L, Hagiwara K
Rev Neurol (Paris) 2019 Jan-Feb;175(1-2):26-37. Epub 2018 Oct 26 doi: 10.1016/j.neurol.2018.09.015. PMID: 30482566
Sène D
Joint Bone Spine 2018 Oct;85(5):553-559. Epub 2017 Nov 16 doi: 10.1016/j.jbspin.2017.11.002. PMID: 29154979
Strupp M, Kim JS, Murofushi T, Straumann D, Jen JC, Rosengren SM, Della Santina CC, Kingma H
J Vestib Res 2017;27(4):177-189. doi: 10.3233/VES-170619. PMID: 29081426Free PMC Article

Recent clinical studies

Etiology

Zhang Z, Wang Y, Luo T, Qi H, Cai L, Yuan Y, Li J
BMC Neurol 2022 Feb 15;22(1):58. doi: 10.1186/s12883-022-02579-4. PMID: 35168549Free PMC Article
Eftimov F, Lucke IM, Querol LA, Rajabally YA, Verhamme C
Brain 2020 Dec 5;143(11):3214-3224. doi: 10.1093/brain/awaa265. PMID: 33155018Free PMC Article
Zhu B, Coppola G, Shoaran M
Cephalalgia 2019 Aug;39(9):1143-1155. Epub 2019 Mar 26 doi: 10.1177/0333102419839975. PMID: 30913908
Garcia-Larrea L, Hagiwara K
Rev Neurol (Paris) 2019 Jan-Feb;175(1-2):26-37. Epub 2018 Oct 26 doi: 10.1016/j.neurol.2018.09.015. PMID: 30482566
Kuwabara S, Sekiguchi Y, Misawa S
Clin Neurophysiol 2017 Jan;128(1):215-219. Epub 2016 Nov 20 doi: 10.1016/j.clinph.2016.11.009. PMID: 27923188

Diagnosis

Eftimov F, Lucke IM, Querol LA, Rajabally YA, Verhamme C
Brain 2020 Dec 5;143(11):3214-3224. doi: 10.1093/brain/awaa265. PMID: 33155018Free PMC Article
Garcia-Larrea L, Hagiwara K
Rev Neurol (Paris) 2019 Jan-Feb;175(1-2):26-37. Epub 2018 Oct 26 doi: 10.1016/j.neurol.2018.09.015. PMID: 30482566
Macerollo A, Brown MJN, Kilner JM, Chen R
Trends Neurosci 2018 May;41(5):294-310. Epub 2018 Mar 14 doi: 10.1016/j.tins.2018.02.007. PMID: 29549962
Horn J, Tjepkema-Cloostermans MC
Semin Neurol 2017 Feb;37(1):60-65. Epub 2017 Feb 1 doi: 10.1055/s-0036-1594252. PMID: 28147419
Kuwabara S, Sekiguchi Y, Misawa S
Clin Neurophysiol 2017 Jan;128(1):215-219. Epub 2016 Nov 20 doi: 10.1016/j.clinph.2016.11.009. PMID: 27923188

Therapy

Sultan I, Brown JA, Serna-Gallegos D, Thirumala PD, Balzer JR, Paras S, Fleseriu C, Crammond DJ, Anetakis KM, Kilic A, Navid F, Gleason TG
J Thorac Cardiovasc Surg 2023 Jun;165(6):1971-1981.e2. Epub 2021 Jul 22 doi: 10.1016/j.jtcvs.2021.07.025. PMID: 34384591
Yoon JT, Nesbitt J, Raynor BL, Roth M, Zertan CC, Jennings JW
J Vasc Interv Radiol 2020 Jun;31(6):903-911. Epub 2020 Apr 25 doi: 10.1016/j.jvir.2019.12.015. PMID: 32340861
Zhu B, Coppola G, Shoaran M
Cephalalgia 2019 Aug;39(9):1143-1155. Epub 2019 Mar 26 doi: 10.1177/0333102419839975. PMID: 30913908
Sène D
Joint Bone Spine 2018 Oct;85(5):553-559. Epub 2017 Nov 16 doi: 10.1016/j.jbspin.2017.11.002. PMID: 29154979
Hacke W
Cent Nerv Syst Trauma 1985 Summer;2(2):123-36. doi: 10.1089/cns.1985.2.123. PMID: 2937558

Prognosis

Wuschek A, Bussas M, El Husseini M, Harabacz L, Pineker V, Pongratz V, Berthele A, Riederer I, Zimmer C, Hemmer B, Kirschke JS, Mühlau M
J Neurol 2023 Feb;270(2):824-830. Epub 2022 Oct 7 doi: 10.1007/s00415-022-11407-1. PMID: 36205793Free PMC Article
Lori S, Bertini G, Bastianelli ME, Gabbanini S, Cossu C, Mortilla M, Dani C
Dev Med Child Neurol 2022 Sep;64(9):1123-1130. Epub 2022 Feb 28 doi: 10.1111/dmcn.15190. PMID: 35225350
Sène D
Joint Bone Spine 2018 Oct;85(5):553-559. Epub 2017 Nov 16 doi: 10.1016/j.jbspin.2017.11.002. PMID: 29154979
Horn J, Tjepkema-Cloostermans MC
Semin Neurol 2017 Feb;37(1):60-65. Epub 2017 Feb 1 doi: 10.1055/s-0036-1594252. PMID: 28147419
Kuwabara S, Sekiguchi Y, Misawa S
Clin Neurophysiol 2017 Jan;128(1):215-219. Epub 2016 Nov 20 doi: 10.1016/j.clinph.2016.11.009. PMID: 27923188

Clinical prediction guides

Latorre A, Belvisi D, Rothwell JC, Bhatia KP, Rocchi L
Clin Neurophysiol 2023 Dec;156:125-139. Epub 2023 Oct 31 doi: 10.1016/j.clinph.2023.10.007. PMID: 37948946
Lori S, Bertini G, Bastianelli ME, Gabbanini S, Cossu C, Mortilla M, Dani C
Dev Med Child Neurol 2022 Sep;64(9):1123-1130. Epub 2022 Feb 28 doi: 10.1111/dmcn.15190. PMID: 35225350
Zhang Z, Wang Y, Luo T, Qi H, Cai L, Yuan Y, Li J
BMC Neurol 2022 Feb 15;22(1):58. doi: 10.1186/s12883-022-02579-4. PMID: 35168549Free PMC Article
Macerollo A, Brown MJN, Kilner JM, Chen R
Trends Neurosci 2018 May;41(5):294-310. Epub 2018 Mar 14 doi: 10.1016/j.tins.2018.02.007. PMID: 29549962
Horn J, Tjepkema-Cloostermans MC
Semin Neurol 2017 Feb;37(1):60-65. Epub 2017 Feb 1 doi: 10.1055/s-0036-1594252. PMID: 28147419

Recent systematic reviews

Sysoeva OV, Smirnov K, Stroganova TA
Clin Neurophysiol 2020 Jan;131(1):213-224. Epub 2019 Nov 21 doi: 10.1016/j.clinph.2019.11.003. PMID: 31812082
Korupolu R, Stampas A, Singh M, Zhou P, Francisco G
Top Spinal Cord Inj Rehabil 2019 Fall;25(4):340-354. doi: 10.1310/sci2504-340. PMID: 31844386Free PMC Article
Tedesco Triccas L, Meyer S, Mantini D, Camilleri K, Falzon O, Camilleri T, Verheyden G
J Neurosci Methods 2019 Jan 1;311:318-330. Epub 2018 Aug 14 doi: 10.1016/j.jneumeth.2018.08.009. PMID: 30118725
Alcantara J, Alcantara JD, Alcantara J
Explore (NY) 2011 Nov-Dec;7(6):384-90. doi: 10.1016/j.explore.2011.08.001. PMID: 22051563
Robinson LR, Micklesen PJ, Tirschwell DL, Lew HL
Crit Care Med 2003 Mar;31(3):960-7. doi: 10.1097/01.CCM.0000053643.21751.3B. PMID: 12627012

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