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Wide humeral diaphysis

MedGen UID:
867340
•Concept ID:
C4021704
•
Anatomical Abnormality
Synonyms: Broad humeral diaphysis; Broad shaft of long bone in upper arm; Wide shaft of long bone in upper arm
 
HPO: HP:0003935

Definition

Increased width of the humeral diaphysis. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVWide humeral diaphysis

Professional guidelines

PubMed

Development and validation of the AO pediatric comprehensive classification of long bone fractures by the Pediatric Expert Group of the AO Foundation in collaboration with AO Clinical Investigation and Documentation and the International Association for Pediatric Traumatology.
Slongo T, Audigé L, Schlickewei W, Clavert JM, Hunter J; International Association for Pediatric Traumatology
J Pediatr Orthop 2006 Jan-Feb;26(1):43-9. doi: 10.1097/01.bpo.0000187989.64021.ml. PMID: 16439900
The management of diaphyseal fractures of the long bones in Finland: a nation-wide survey.
Böstman O, Rokkanen P
Ann Chir Gynaecol 1986;75(6):333-6. PMID: 3579194

Recent clinical studies

Etiology

Titanium vs. carbon fiber-reinforced intramedullary nailing for humeral bone tumors.
Bhashyam AR, Yeung C, Sodhi A, Xu RF, Groot OQ, Kelly S, Lozano-Calderon S
J Shoulder Elbow Surg 2023 Nov;32(11):2286-2295. Epub 2023 May 30 doi: 10.1016/j.jse.2023.04.023. PMID: 37263478
Intercalary frozen autografts for reconstruction of bone defects following meta-/diaphyseal tumor resection at the extremities.
Yang J, Li W, Feng R, Li D
BMC Musculoskelet Disord 2022 Sep 30;23(1):890. doi: 10.1186/s12891-022-05840-6. PMID: 36180843Free PMC Article
Preliminary results after reconstruction of bony defects of the proximal humerus with an allograft-resurfacing composite.
Ruggieri P, Mavrogenis AF, Guerra G, Mercuri M
J Bone Joint Surg Br 2011 Aug;93(8):1098-103. doi: 10.1302/0301-620X.93B8.26011. PMID: 21768636
Limb bone bilateral asymmetry: variability and commonality among modern humans.
Auerbach BM, Ruff CB
J Hum Evol 2006 Feb;50(2):203-18. Epub 2005 Nov 28 doi: 10.1016/j.jhevol.2005.09.004. PMID: 16310833
Metastatic bone disease of the humerus.
Frassica FJ, Frassica DA
J Am Acad Orthop Surg 2003 Jul-Aug;11(4):282-8. doi: 10.5435/00124635-200307000-00008. PMID: 12889867

Diagnosis

Proband and the Brother.
B S, Kotha JP
J Assoc Physicians India 2023 Jan;71(1):1. PMID: 37116016
Anterior minimally invasive bridge-plate technique for treatment of humeral shaft nonunion.
Vilaça PR Jr, Uezumi MK
J Orthop Traumatol 2012 Dec;13(4):211-6. Epub 2012 Jun 21 doi: 10.1007/s10195-012-0203-1. PMID: 22717617Free PMC Article
The AO comprehensive classification of pediatric long-bone fractures: a web-based multicenter agreement study.
Slongo T, Audigé L, Clavert JM, Lutz N, Frick S, Hunter J
J Pediatr Orthop 2007 Mar;27(2):171-80. doi: 10.1097/01.bpb.0000248569.43251.f9. PMID: 17314642
Development and validation of the AO pediatric comprehensive classification of long bone fractures by the Pediatric Expert Group of the AO Foundation in collaboration with AO Clinical Investigation and Documentation and the International Association for Pediatric Traumatology.
Slongo T, Audigé L, Schlickewei W, Clavert JM, Hunter J; International Association for Pediatric Traumatology
J Pediatr Orthop 2006 Jan-Feb;26(1):43-9. doi: 10.1097/01.bpo.0000187989.64021.ml. PMID: 16439900
Low-grade fibrosarcoma of the proximal humerus.
Saito T, Oda Y, Tanaka K, Matsuda S, Sakamoto A, Yamamoto H, Iwamoto Y, Tsuneyoshi M
Pathol Int 2003 Feb;53(2):115-20. doi: 10.1046/j.1440-1827.2003.01440.x. PMID: 12588441

Therapy

Intercalary frozen autografts for reconstruction of bone defects following meta-/diaphyseal tumor resection at the extremities.
Yang J, Li W, Feng R, Li D
BMC Musculoskelet Disord 2022 Sep 30;23(1):890. doi: 10.1186/s12891-022-05840-6. PMID: 36180843Free PMC Article
Outcome of segmental prosthesis reconstruction for diaphyseal bone tumors: a multi-center retrospective study.
Zheng K, Yu XC, Hu YC, Shao ZW, Xu M, Wang BC, Wang F
BMC Cancer 2019 Jun 28;19(1):638. doi: 10.1186/s12885-019-5865-0. PMID: 31253134Free PMC Article
Attenuation of Antiresorptive Action in Withdrawal of Minodronic Acid for Three Months After Treatment for Twelve Months in Ovariectomized Rats.
Tanaka M, Mori H, Kawabata K
Calcif Tissue Int 2015 Oct;97(4):402-11. Epub 2015 Jun 6 doi: 10.1007/s00223-015-0017-2. PMID: 26048283
Sandwich allografts for long-bone nonunions in patients with osteogenesis imperfecta: a retrospective study.
Puvanesarajah V, Shapiro JR, Sponseller PD
J Bone Joint Surg Am 2015 Feb 18;97(4):318-25. doi: 10.2106/JBJS.N.00584. PMID: 25695984
Preliminary results after reconstruction of bony defects of the proximal humerus with an allograft-resurfacing composite.
Ruggieri P, Mavrogenis AF, Guerra G, Mercuri M
J Bone Joint Surg Br 2011 Aug;93(8):1098-103. doi: 10.1302/0301-620X.93B8.26011. PMID: 21768636

Prognosis

Radiation-free interlocking intramedullary nailing of three-hundred and seventy long bone fractures in Ogbomoso, Nigeria.
Adesina SA, Eyesan SU, Ikem IC, Anipole OA, Amole IO, Akinwumi AI, Bamigboye PO, Durodola AO
Sci Rep 2021 May 12;11(1):10070. doi: 10.1038/s41598-021-89544-2. PMID: 33980924Free PMC Article
A Modified Rotator Cuff Sparing Approach to the Proximal Humerus in Antegrade Nail Osteosynthesis with Transosseous Supraspinatus Tendon Refixation.
Ateschrang A, Gratzer C, Stöckle U, Schreiner AJ
Z Orthop Unfall 2019 Dec;157(6):706-714. Epub 2019 Sep 2 doi: 10.1055/a-0853-7882. PMID: 31476789
Sandwich allografts for long-bone nonunions in patients with osteogenesis imperfecta: a retrospective study.
Puvanesarajah V, Shapiro JR, Sponseller PD
J Bone Joint Surg Am 2015 Feb 18;97(4):318-25. doi: 10.2106/JBJS.N.00584. PMID: 25695984
Outcome of the intramedullary diaphyseal segmental defect fixation system for bone tumors.
Ruggieri P, Mavrogenis AF, Bianchi G, Sakellariou VI, Mercuri M, Papagelopoulos PJ
J Surg Oncol 2011 Jul 1;104(1):83-90. Epub 2011 Mar 4 doi: 10.1002/jso.21893. PMID: 21381038
Metastatic bone disease of the humerus.
Frassica FJ, Frassica DA
J Am Acad Orthop Surg 2003 Jul-Aug;11(4):282-8. doi: 10.5435/00124635-200307000-00008. PMID: 12889867

Clinical prediction guides

Titanium vs. carbon fiber-reinforced intramedullary nailing for humeral bone tumors.
Bhashyam AR, Yeung C, Sodhi A, Xu RF, Groot OQ, Kelly S, Lozano-Calderon S
J Shoulder Elbow Surg 2023 Nov;32(11):2286-2295. Epub 2023 May 30 doi: 10.1016/j.jse.2023.04.023. PMID: 37263478
Intercalary frozen autografts for reconstruction of bone defects following meta-/diaphyseal tumor resection at the extremities.
Yang J, Li W, Feng R, Li D
BMC Musculoskelet Disord 2022 Sep 30;23(1):890. doi: 10.1186/s12891-022-05840-6. PMID: 36180843Free PMC Article
Biological reconstruction in the treatment of extremity sarcoma in femur, tibia, and humerus.
Yao W, Cai Q, Wang J, Zhang P, Wang X, Du X, Niu X
Medicine (Baltimore) 2020 Jul 2;99(27):e20715. doi: 10.1097/MD.0000000000020715. PMID: 32629645Free PMC Article
Outcome of segmental prosthesis reconstruction for diaphyseal bone tumors: a multi-center retrospective study.
Zheng K, Yu XC, Hu YC, Shao ZW, Xu M, Wang BC, Wang F
BMC Cancer 2019 Jun 28;19(1):638. doi: 10.1186/s12885-019-5865-0. PMID: 31253134Free PMC Article
Preliminary results after reconstruction of bony defects of the proximal humerus with an allograft-resurfacing composite.
Ruggieri P, Mavrogenis AF, Guerra G, Mercuri M
J Bone Joint Surg Br 2011 Aug;93(8):1098-103. doi: 10.1302/0301-620X.93B8.26011. PMID: 21768636

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