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Abnormality of Krebs cycle metabolism

MedGen UID:
867422
Concept ID:
C4021795
Finding
Synonyms: Abnormality of citric acid cycle; Abnormality of the tricarboxylic cycle
 
HPO: HP:0000816

Definition

An abnormality of the tricarboxylic acid cycle. [from HPO]

Professional guidelines

PubMed

Liu J, Bai X, Zhang M, Wu S, Xiao J, Zeng X, Li Y, Zhang Z
Clin Transl Oncol 2024 Feb;26(2):338-351. Epub 2023 Jul 21 doi: 10.1007/s12094-023-03278-3. PMID: 37477784
Ebertowska A, Ludkiewicz B, Klejbor I, Melka N, Moryś J
Folia Morphol (Warsz) 2020;79(2):191-197. Epub 2020 Feb 19 doi: 10.5603/FM.a2020.0020. PMID: 32073132
Bonda DJ, Wang X, Perry G, Smith MA, Zhu X
Drugs Aging 2010 Mar 1;27(3):181-92. doi: 10.2165/11532140-000000000-00000. PMID: 20210366Free PMC Article

Recent clinical studies

Etiology

Zhou YF, Hou YY, Ban Q, Zhang ML, Huang T, Ma B, Shi L, Zhang Q
Andrology 2023 Oct;11(7):1303-1319. Epub 2023 Mar 20 doi: 10.1111/andr.13412. PMID: 36841993
Kantorovich V, Pacak K
F1000Res 2018;7 Epub 2018 Sep 20 doi: 10.12688/f1000research.14568.1. PMID: 30345003Free PMC Article
Bloomgarden Z
J Diabetes 2018 May;10(5):350-352. Epub 2018 Feb 13 doi: 10.1111/1753-0407.12645. PMID: 29369529
Björklund P, Pacak K, Crona J
J Intern Med 2016 Dec;280(6):559-573. Epub 2016 May 10 doi: 10.1111/joim.12507. PMID: 27165774Free PMC Article
Zeviani M, Bonilla E, DeVivo DC, DiMauro S
Neurol Clin 1989 Feb;7(1):123-56. PMID: 2646519

Diagnosis

Kantorovich V, Pacak K
F1000Res 2018;7 Epub 2018 Sep 20 doi: 10.12688/f1000research.14568.1. PMID: 30345003Free PMC Article
Mascalchi M, Montomoli M, Guerrini R
Essays Biochem 2018 Jul 20;62(3):409-421. doi: 10.1042/EBC20170109. PMID: 30030366
Bloomgarden Z
J Diabetes 2018 May;10(5):350-352. Epub 2018 Feb 13 doi: 10.1111/1753-0407.12645. PMID: 29369529
Naviaux RK
Mitochondrion 2014 May;16:7-17. Epub 2013 Aug 24 doi: 10.1016/j.mito.2013.08.006. PMID: 23981537
De Meirleir L
J Child Neurol 2002 Dec;17 Suppl 3:3S26-33; discussion 3S33-4. PMID: 12597053

Therapy

Khan MA, Zubair H, Anand S, Srivastava SK, Singh S, Singh AP
Cancer Lett 2020 Mar 31;473:176-185. Epub 2020 Jan 7 doi: 10.1016/j.canlet.2020.01.003. PMID: 31923436Free PMC Article
Bloomgarden Z
J Diabetes 2018 May;10(5):350-352. Epub 2018 Feb 13 doi: 10.1111/1753-0407.12645. PMID: 29369529
Tella SH, Taïeb D, Pacak K
Eur J Cancer 2017 Nov;86:1-4. Epub 2017 Sep 22 doi: 10.1016/j.ejca.2017.08.023. PMID: 28946040Free PMC Article
Caudarella R, Vescini F
Arch Ital Urol Androl 2009 Sep;81(3):182-7. PMID: 19911682
Sherlock S, Parbhoo SP
Postgrad Med J 1971 Jul;47(549):493-8. doi: 10.1136/pgmj.47.549.493. PMID: 4934637Free PMC Article

Prognosis

Liu J, Bai X, Zhang M, Wu S, Xiao J, Zeng X, Li Y, Zhang Z
Clin Transl Oncol 2024 Feb;26(2):338-351. Epub 2023 Jul 21 doi: 10.1007/s12094-023-03278-3. PMID: 37477784
Yamazaki Y, Gao X, Pecori A, Nakamura Y, Tezuka Y, Omata K, Ono Y, Morimoto R, Satoh F, Sasano H
Front Endocrinol (Lausanne) 2020;11:587769. Epub 2020 Oct 27 doi: 10.3389/fendo.2020.587769. PMID: 33193100Free PMC Article
Björklund P, Pacak K, Crona J
J Intern Med 2016 Dec;280(6):559-573. Epub 2016 May 10 doi: 10.1111/joim.12507. PMID: 27165774Free PMC Article
Yang OC, Maxwell PH, Pollard PJ
Kidney Int 2013 Oct;84(4):667-81. Epub 2013 Jul 3 doi: 10.1038/ki.2013.245. PMID: 23823604
Linehan WM, Srinivasan R, Schmidt LS
Nat Rev Urol 2010 May;7(5):277-85. doi: 10.1038/nrurol.2010.47. PMID: 20448661Free PMC Article

Clinical prediction guides

Córdoba-Jover B, Ribera J, Portolés I, Lecue E, Rodriguez-Vita J, Pérez-Sisqués L, Mannara F, Solsona-Vilarrasa E, García-Ruiz C, Fernández-Checa JC, Casals G, Rodríguez-Revenga L, Álvarez-Mora MI, Arteche-López A, Díaz de Bustamante A, Calvo R, Pujol A, Azkargorta M, Elortza F, Malagelada C, Pinyol R, Huguet-Pradell J, Melgar-Lesmes P, Jiménez W, Morales-Ruiz M
Liver Int 2023 Aug;43(8):1822-1836. Epub 2023 Jun 14 doi: 10.1111/liv.15640. PMID: 37312667
Bloomgarden Z
J Diabetes 2018 May;10(5):350-352. Epub 2018 Feb 13 doi: 10.1111/1753-0407.12645. PMID: 29369529
Bar-Or D, Carrick M, Tanner A 2nd, Lieser MJ, Rael LT, Brody E
J Crit Care 2018 Feb;43:197-201. Epub 2017 Sep 8 doi: 10.1016/j.jcrc.2017.09.012. PMID: 28915394
Krzysztoń-Russjan J
Postepy Hig Med Dosw (Online) 2016 Dec 30;70(0):1331-1342. doi: 10.5604/17322693.1227557. PMID: 28100843
Yang OC, Maxwell PH, Pollard PJ
Kidney Int 2013 Oct;84(4):667-81. Epub 2013 Jul 3 doi: 10.1038/ki.2013.245. PMID: 23823604

Recent systematic reviews

De Spiegeleer M, De Paepe E, Van Meulebroek L, Gies I, De Schepper J, Vanhaecke L
Mol Med 2021 Nov 6;27(1):145. doi: 10.1186/s10020-021-00394-0. PMID: 34742239Free PMC Article

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