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Abnormality of globe location

MedGen UID:
867563
•Concept ID:
C4021946
•
Anatomical Abnormality
Synonyms: Abnormality of eyeball location; Abnormality of eyeball position; Abnormality of globe position
 
HPO: HP:0100886

Definition

An abnormality in the placement of the ocular globe (eyeball). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormality of globe location

Professional guidelines

PubMed

Reconstruction after ablative treatment of arteriovenous malformations of the head and neck.
Chung HY, O TM, Tombris S, Meyer L, Waner M
J Oral Pathol Med 2022 Nov;51(10):872-877. Epub 2022 Nov 22 doi: 10.1111/jop.13368. PMID: 36181711
The Spectrum of PAX6 Mutations and Genotype-Phenotype Correlations in the Eye.
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Genes (Basel) 2019 Dec 17;10(12) doi: 10.3390/genes10121050. PMID: 31861090Free PMC Article
PHACE syndrome: clinical manifestations, diagnostic criteria, and management.
Rotter A, Samorano LP, Rivitti-Machado MC, Oliveira ZNP, Gontijo B
An Bras Dermatol 2018 Jun;93(3):405-411. doi: 10.1590/abd1806-4841.20187693. PMID: 29924216Free PMC Article

Recent clinical studies

Etiology

The role of the microbiota in glaucoma.
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Cell culture models to study retinal pigment epithelium-related pathogenesis in age-related macular degeneration.
Bharti K, den Hollander AI, Lakkaraju A, Sinha D, Williams DS, Finnemann SC, Bowes-Rickman C, Malek G, D'Amore PA
Exp Eye Res 2022 Sep;222:109170. Epub 2022 Jul 11 doi: 10.1016/j.exer.2022.109170. PMID: 35835183Free PMC Article
Dominant Stickler Syndrome.
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Genes (Basel) 2022 Jun 18;13(6) doi: 10.3390/genes13061089. PMID: 35741851Free PMC Article
Venous overload choroidopathy: A hypothetical framework for central serous chorioretinopathy and allied disorders.
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Prog Retin Eye Res 2022 Jan;86:100973. Epub 2021 May 21 doi: 10.1016/j.preteyeres.2021.100973. PMID: 34029721
Descemetocele.
Agarwal R, Nagpal R, Todi V, Sharma N
Surv Ophthalmol 2021 Jan-Feb;66(1):2-19. Epub 2020 Oct 13 doi: 10.1016/j.survophthal.2020.10.004. PMID: 33058926

Diagnosis

Future perspectives for treating patients with geographic atrophy.
Loewenstein A, Trivizki O
Graefes Arch Clin Exp Ophthalmol 2023 Jun;261(6):1525-1531. Epub 2022 Dec 15 doi: 10.1007/s00417-022-05931-z. PMID: 36520185Free PMC Article
Normal and abnormal foveal development.
Thomas MG, Papageorgiou E, Kuht HJ, Gottlob I
Br J Ophthalmol 2022 May;106(5):593-599. Epub 2020 Nov 4 doi: 10.1136/bjophthalmol-2020-316348. PMID: 33148537
International Classification of Retinopathy of Prematurity, Third Edition.
Chiang MF, Quinn GE, Fielder AR, Ostmo SR, Paul Chan RV, Berrocal A, Binenbaum G, Blair M, Peter Campbell J, Capone A Jr, Chen Y, Dai S, Ells A, Fleck BW, Good WV, Elizabeth Hartnett M, Holmstrom G, Kusaka S, Kychenthal A, Lepore D, Lorenz B, Martinez-Castellanos MA, Özdek Ş, Ademola-Popoola D, Reynolds JD, Shah PK, Shapiro M, Stahl A, Toth C, Vinekar A, Visser L, Wallace DK, Wu WC, Zhao P, Zin A
Ophthalmology 2021 Oct;128(10):e51-e68. Epub 2021 Jul 8 doi: 10.1016/j.ophtha.2021.05.031. PMID: 34247850Free PMC Article
Descemetocele.
Agarwal R, Nagpal R, Todi V, Sharma N
Surv Ophthalmol 2021 Jan-Feb;66(1):2-19. Epub 2020 Oct 13 doi: 10.1016/j.survophthal.2020.10.004. PMID: 33058926
Ocular colobomata.
Onwochei BC, Simon JW, Bateman JB, Couture KC, Mir E
Surv Ophthalmol 2000 Nov-Dec;45(3):175-94. doi: 10.1016/s0039-6257(00)00151-x. PMID: 11094243

Therapy

Ocular Ciliopathies: Genetic and Mechanistic Insights into Developing Therapies.
Shivanna M, Anand M, Chakrabarti S, Khanna H
Curr Med Chem 2019;26(17):3120-3131. doi: 10.2174/0929867325666180917102557. PMID: 30221600Free PMC Article
Current and Future Treatments for Graves' Disease and Graves' Ophthalmopathy.
Kotwal A, Stan M
Horm Metab Res 2018 Dec;50(12):871-886. Epub 2018 Oct 4 doi: 10.1055/a-0739-8134. PMID: 30286486
PHACE syndrome: clinical manifestations, diagnostic criteria, and management.
Rotter A, Samorano LP, Rivitti-Machado MC, Oliveira ZNP, Gontijo B
An Bras Dermatol 2018 Jun;93(3):405-411. doi: 10.1590/abd1806-4841.20187693. PMID: 29924216Free PMC Article
Meibomian Gland Dysfunction and Contact Lens Discomfort.
Arita R, Fukuoka S, Morishige N
Eye Contact Lens 2017 Jan;43(1):17-22. doi: 10.1097/ICL.0000000000000351. PMID: 28002224
Idiopathic hypertrophic pachymeningitis.
Kupersmith MJ, Martin V, Heller G, Shah A, Mitnick HJ
Neurology 2004 Mar 9;62(5):686-94. doi: 10.1212/01.wnl.0000113748.53023.b7. PMID: 15007115

Prognosis

Future perspectives for treating patients with geographic atrophy.
Loewenstein A, Trivizki O
Graefes Arch Clin Exp Ophthalmol 2023 Jun;261(6):1525-1531. Epub 2022 Dec 15 doi: 10.1007/s00417-022-05931-z. PMID: 36520185Free PMC Article
Normal and abnormal foveal development.
Thomas MG, Papageorgiou E, Kuht HJ, Gottlob I
Br J Ophthalmol 2022 May;106(5):593-599. Epub 2020 Nov 4 doi: 10.1136/bjophthalmol-2020-316348. PMID: 33148537
Uveal melanoma.
Kashyap S, Meel R, Singh L, Singh M
Semin Diagn Pathol 2016 May;33(3):141-7. Epub 2016 Mar 10 doi: 10.1053/j.semdp.2015.10.005. PMID: 26972224
Idiopathic hypertrophic pachymeningitis.
Kupersmith MJ, Martin V, Heller G, Shah A, Mitnick HJ
Neurology 2004 Mar 9;62(5):686-94. doi: 10.1212/01.wnl.0000113748.53023.b7. PMID: 15007115
Ocular colobomata.
Onwochei BC, Simon JW, Bateman JB, Couture KC, Mir E
Surv Ophthalmol 2000 Nov-Dec;45(3):175-94. doi: 10.1016/s0039-6257(00)00151-x. PMID: 11094243

Clinical prediction guides

Future perspectives for treating patients with geographic atrophy.
Loewenstein A, Trivizki O
Graefes Arch Clin Exp Ophthalmol 2023 Jun;261(6):1525-1531. Epub 2022 Dec 15 doi: 10.1007/s00417-022-05931-z. PMID: 36520185Free PMC Article
Clinical electroretinography in diabetic retinopathy: a review.
McAnany JJ, Persidina OS, Park JC
Surv Ophthalmol 2022 May-Jun;67(3):712-722. Epub 2021 Sep 4 doi: 10.1016/j.survophthal.2021.08.011. PMID: 34487740Free PMC Article
Review of Genotype-Phenotype Correlations in Usher Syndrome.
Nisenbaum E, Thielhelm TP, Nourbakhsh A, Yan D, Blanton SH, Shu Y, Koehler KR, El-Amraoui A, Chen Z, Lam BL, Liu X
Ear Hear 2022 Jan/Feb;43(1):1-8. doi: 10.1097/AUD.0000000000001066. PMID: 34039936Free PMC Article
Normal and abnormal foveal development.
Thomas MG, Papageorgiou E, Kuht HJ, Gottlob I
Br J Ophthalmol 2022 May;106(5):593-599. Epub 2020 Nov 4 doi: 10.1136/bjophthalmol-2020-316348. PMID: 33148537
Paramacular coloboma.
Pian D, Ferrucci S, Anderson SF, Wu C
Optom Vis Sci 2003 Aug;80(8):556-63. doi: 10.1097/00006324-200308000-00008. PMID: 12917574

Recent systematic reviews

Correlation between Phenotype and Genotype in CTNNB1 Syndrome: A Systematic Review of the Literature.
Miroševič Š, Khandelwal S, Sušjan P, Žakelj N, Gosar D, Forstnerič V, Lainšček D, Jerala R, Osredkar D
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Clinical application of ultra-widefield fundus autofluorescence.
Xu A, Chen C
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Prevalence and causes of childhood blindness in India: A systematic review.
Wadhwani M, Vashist P, Singh SS, Gupta V, Gupta N, Saxena R
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Subepidermal Calcinosis in the Ocular Adnexa: A Systematic Review.
Khine KT, Shi DS, Bernhisel A, Gertsch KR, Mamalis N, Patel BCK, Dutton JJ
Ophthalmic Plast Reconstr Surg 2018 Mar/Apr;34(2):101-105. doi: 10.1097/IOP.0000000000000936. PMID: 28430707
Interventions for chronic blepharitis.
Lindsley K, Matsumura S, Hatef E, Akpek EK
Cochrane Database Syst Rev 2012 May 16;2012(5):CD005556. doi: 10.1002/14651858.CD005556.pub2. PMID: 22592706Free PMC Article

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