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Tarsometatarsal synostosis

MedGen UID:
Concept ID:
Congenital Abnormality
Synonym: Fused bones of the midfoot
HPO: HP:0100329

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTarsometatarsal synostosis

Conditions with this feature

Mesomelia-synostoses syndrome
MedGen UID:
Concept ID:
Disease or Syndrome
The Verloes-David-Pfeiffer mesomelia-synostoses syndrome is an autosomal dominant form of mesomelic dysplasia comprising typical acral synostoses combined with ptosis, hypertelorism, palatal abnormality, congenital heart disease, and ureteral anomalies (summary by Isidor et al., 2009). Mesomelia and synostoses are also cardinal features of the Kantaputra type of mesomelic dysplasia (156232).

Recent clinical studies


Domingues GM, da Silva TT, Aihara AY, Cardoso FN, Barreto VO
Acta Radiol 2020 Nov;61(11):1541-1544. Epub 2020 Feb 19 doi: 10.1177/0284185120905034. PMID: 32075412


Yeganeh A, Hajializade M, Mahdavi SM, Eraghi AS, Moghtadaei M
J Foot Ankle Surg 2020 Mar-Apr;59(2):385-387. doi: 10.1053/j.jfas.2019.08.001. PMID: 32131007
Gutman E
South Med J 1981 Jan;74(1):78-9. PMID: 7455750

Clinical prediction guides

Leroy JG, Claus L, Lee B, Mortier GR
Pediatr Pathol Mol Med 2003 Jan-Feb;22(1):23-35. doi: 10.1080/pdp. PMID: 12687887

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