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Chagas cardiomyopathy

MedGen UID:
868
Concept ID:
C0007930
Disease or Syndrome
Synonyms: Cardiomyopathy, Chagas; Cardiomyopathy, Chagas'; Cardiovascular Trypanosomiasis; Chagas Cardiomyopathy; Chagas' Cardiomyopathy; Trypanosomiasis, Cardiovascular
SNOMED CT: Chagas' disease with heart involvement (998008)
 
Monarch Initiative: MONDO:0005491

Definition

A dilated cardiomyopathy caused by the protozoan Trypanosoma cruzi. Patients may present with heart block, congestive heart failure, or anginal symptoms. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Swett MC, Rayes DL, Campos SV, Kumar RN
Curr Cardiol Rep 2024 Oct;26(10):1105-1112. Epub 2024 Aug 8 doi: 10.1007/s11886-024-02113-7. PMID: 39115799
Santos É, Menezes Falcão L
Rev Port Cardiol (Engl Ed) 2020 May;39(5):279-289. Epub 2020 Jun 10 doi: 10.1016/j.repc.2019.12.006. PMID: 32532535
Nunes MCP, Beaton A, Acquatella H, Bern C, Bolger AF, Echeverría LE, Dutra WO, Gascon J, Morillo CA, Oliveira-Filho J, Ribeiro ALP, Marin-Neto JA; American Heart Association Rheumatic Fever, Endocarditis and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young; Council on Cardiovascular and Stroke Nursing; and Stroke Council
Circulation 2018 Sep 18;138(12):e169-e209. doi: 10.1161/CIR.0000000000000599. PMID: 30354432

Recent clinical studies

Etiology

Gadioli LP, Schmidt A, Maciel BC, Volpe GJ, Simões MV, Marin-Neto JA
Curr Cardiol Rep 2024 Jun;26(6):635-641. Epub 2024 Apr 24 doi: 10.1007/s11886-024-02057-y. PMID: 38656586
Nunes MCP, Beaton A, Acquatella H, Bern C, Bolger AF, Echeverría LE, Dutra WO, Gascon J, Morillo CA, Oliveira-Filho J, Ribeiro ALP, Marin-Neto JA; American Heart Association Rheumatic Fever, Endocarditis and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young; Council on Cardiovascular and Stroke Nursing; and Stroke Council
Circulation 2018 Sep 18;138(12):e169-e209. doi: 10.1161/CIR.0000000000000599. PMID: 30354432
Trachtenberg BH, Hare JM
Circ Res 2017 Sep 15;121(7):803-818. doi: 10.1161/CIRCRESAHA.117.310221. PMID: 28912184
Benatti RD, Oliveira GH, Bacal F
J Heart Lung Transplant 2017 Jun;36(6):597-603. Epub 2017 Feb 3 doi: 10.1016/j.healun.2017.02.006. PMID: 28284779
Rassi A Jr, Rassi A, Marin-Neto JA
Lancet 2010 Apr 17;375(9723):1388-402. doi: 10.1016/S0140-6736(10)60061-X. PMID: 20399979

Diagnosis

Echavarría NG, Echeverría LE, Stewart M, Gallego C, Saldarriaga C
Curr Probl Cardiol 2021 Mar;46(3):100507. Epub 2019 Dec 1 doi: 10.1016/j.cpcardiol.2019.100507. PMID: 31983471
Santos É, Menezes Falcão L
Rev Port Cardiol (Engl Ed) 2020 May;39(5):279-289. Epub 2020 Jun 10 doi: 10.1016/j.repc.2019.12.006. PMID: 32532535
Nunes MCP, Beaton A, Acquatella H, Bern C, Bolger AF, Echeverría LE, Dutra WO, Gascon J, Morillo CA, Oliveira-Filho J, Ribeiro ALP, Marin-Neto JA; American Heart Association Rheumatic Fever, Endocarditis and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young; Council on Cardiovascular and Stroke Nursing; and Stroke Council
Circulation 2018 Sep 18;138(12):e169-e209. doi: 10.1161/CIR.0000000000000599. PMID: 30354432
Mangini S, Alves BR, Silvestre OM, Pires PV, Pires LJ, Curiati MN, Bacal F
Einstein (Sao Paulo) 2015 Apr-Jun;13(2):310-8. doi: 10.1590/S1679-45082015RW3154. PMID: 26154552Free PMC Article
Rassi A Jr, Rassi A, Marin-Neto JA
Lancet 2010 Apr 17;375(9723):1388-402. doi: 10.1016/S0140-6736(10)60061-X. PMID: 20399979

Therapy

Santos É, Menezes Falcão L
Rev Port Cardiol (Engl Ed) 2020 May;39(5):279-289. Epub 2020 Jun 10 doi: 10.1016/j.repc.2019.12.006. PMID: 32532535
Nunes MCP, Beaton A, Acquatella H, Bern C, Bolger AF, Echeverría LE, Dutra WO, Gascon J, Morillo CA, Oliveira-Filho J, Ribeiro ALP, Marin-Neto JA; American Heart Association Rheumatic Fever, Endocarditis and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young; Council on Cardiovascular and Stroke Nursing; and Stroke Council
Circulation 2018 Sep 18;138(12):e169-e209. doi: 10.1161/CIR.0000000000000599. PMID: 30354432
Trachtenberg BH, Hare JM
Circ Res 2017 Sep 15;121(7):803-818. doi: 10.1161/CIRCRESAHA.117.310221. PMID: 28912184
Mangini S, Alves BR, Silvestre OM, Pires PV, Pires LJ, Curiati MN, Bacal F
Einstein (Sao Paulo) 2015 Apr-Jun;13(2):310-8. doi: 10.1590/S1679-45082015RW3154. PMID: 26154552Free PMC Article
Rassi A Jr, Rassi A, Marin-Neto JA
Lancet 2010 Apr 17;375(9723):1388-402. doi: 10.1016/S0140-6736(10)60061-X. PMID: 20399979

Prognosis

Jimenez A, Winokur EJ
Dimens Crit Care Nurs 2023 Jul-Aug 01;42(4):202-210. doi: 10.1097/DCC.0000000000000590. PMID: 37219474
Santos É, Menezes Falcão L
Rev Port Cardiol (Engl Ed) 2020 May;39(5):279-289. Epub 2020 Jun 10 doi: 10.1016/j.repc.2019.12.006. PMID: 32532535
Nunes MCP, Beaton A, Acquatella H, Bern C, Bolger AF, Echeverría LE, Dutra WO, Gascon J, Morillo CA, Oliveira-Filho J, Ribeiro ALP, Marin-Neto JA; American Heart Association Rheumatic Fever, Endocarditis and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young; Council on Cardiovascular and Stroke Nursing; and Stroke Council
Circulation 2018 Sep 18;138(12):e169-e209. doi: 10.1161/CIR.0000000000000599. PMID: 30354432
Brito BOF, Ribeiro ALP
Rev Soc Bras Med Trop 2018 Sep-Oct;51(5):570-577. doi: 10.1590/0037-8682-0184-2018. PMID: 30304260
Trachtenberg BH, Hare JM
Circ Res 2017 Sep 15;121(7):803-818. doi: 10.1161/CIRCRESAHA.117.310221. PMID: 28912184

Clinical prediction guides

Andrade MV, Noronha KVMS, de Souza A, Motta-Santos AS, Braga PEF, Bracarense H, de Miranda MCC, Nascimento BR, Molina I, Martins-Melo FR, Perel P, Geissbühler Y, Quijano M, Machado IE, Ribeiro ALP
PLoS Negl Trop Dis 2023 Nov;17(11):e0011757. Epub 2023 Nov 22 doi: 10.1371/journal.pntd.0011757. PMID: 37992061Free PMC Article
Velasco A, Morillo CA
J Nucl Cardiol 2020 Apr;27(2):445-451. Epub 2018 Jul 18 doi: 10.1007/s12350-018-1361-1. PMID: 30022404
Nunes MCP, Beaton A, Acquatella H, Bern C, Bolger AF, Echeverría LE, Dutra WO, Gascon J, Morillo CA, Oliveira-Filho J, Ribeiro ALP, Marin-Neto JA; American Heart Association Rheumatic Fever, Endocarditis and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young; Council on Cardiovascular and Stroke Nursing; and Stroke Council
Circulation 2018 Sep 18;138(12):e169-e209. doi: 10.1161/CIR.0000000000000599. PMID: 30354432
Brito BOF, Ribeiro ALP
Rev Soc Bras Med Trop 2018 Sep-Oct;51(5):570-577. doi: 10.1590/0037-8682-0184-2018. PMID: 30304260
Nunes MC, Guimarães Júnior MH, Diamantino AC, Gelape CL, Ferrari TC
Heart 2017 May;103(9):651-658. Epub 2017 Mar 11 doi: 10.1136/heartjnl-2016-309870. PMID: 28285268

Recent systematic reviews

Mazzoli-Rocha F, Diniz CP, Rezende DPR, Mendes FSNS, Hasslocher-Moreno AM, Sousa AS, Saraiva RM, Borghi-Silva A, Mediano MFF, Alexandre DJA
Rev Soc Bras Med Trop 2023;56:0389. Epub 2023 Dec 8 doi: 10.1590/0037-8682-0389-2023. PMID: 38088665Free PMC Article
Andrade MV, Noronha KVMS, de Souza A, Motta-Santos AS, Braga PEF, Bracarense H, de Miranda MCC, Nascimento BR, Molina I, Martins-Melo FR, Perel P, Geissbühler Y, Quijano M, Machado IE, Ribeiro ALP
PLoS Negl Trop Dis 2023 Nov;17(11):e0011757. Epub 2023 Nov 22 doi: 10.1371/journal.pntd.0011757. PMID: 37992061Free PMC Article
Cutshaw MK, Sciaudone M, Bowman NM
Am J Trop Med Hyg 2023 Apr 5;108(4):791-800. Epub 2023 Feb 27 doi: 10.4269/ajtmh.22-0630. PMID: 36848894Free PMC Article
Chadalawada S, Rassi A Jr, Samara O, Monzon A, Gudapati D, Vargas Barahona L, Hyson P, Sillau S, Mestroni L, Taylor M, da Consolação Vieira Moreira M, DeSanto K, Agudelo Higuita NI, Franco-Paredes C, Henao-Martínez AF
ESC Heart Fail 2021 Dec;8(6):5466-5481. Epub 2021 Oct 30 doi: 10.1002/ehf2.13648. PMID: 34716744Free PMC Article
Pereira Júnior Cde B, Markman Filho B
Arq Bras Cardiol 2014 Jun;102(6):602-10. Epub 2014 Jun 6 doi: 10.5935/abc.20140068. PMID: 25004422Free PMC Article

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