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Abnormal mediastinum morphology

MedGen UID:
868004
•Concept ID:
C4022395
•
Anatomical Abnormality
Synonym: Abnormality of the mediastinum
 
HPO: HP:0045026

Definition

Any structural anomaly of the central compartment of the thoracic cavity. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal mediastinum morphology

Professional guidelines

PubMed

Surgery for total anomalous pulmonary venous connection: primary sutureless repair vs. conventional repair.
Yoshimura N, Fukahara K, Yamashita A, Doi T, Takeuchi K, Yamashita S, Homma T, Yokoyama S, Aoki M, Ikeno Y
Gen Thorac Cardiovasc Surg 2017 May;65(5):245-251. Epub 2017 Mar 22 doi: 10.1007/s11748-017-0769-x. PMID: 28332089
Methods for staging non-small cell lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines.
Silvestri GA, Gonzalez AV, Jantz MA, Margolis ML, Gould MK, Tanoue LT, Harris LJ, Detterbeck FC
Chest 2013 May;143(5 Suppl):e211S-e250S. doi: 10.1378/chest.12-2355. PMID: 23649440
Role of imaging in the diagnosis, staging, and treatment of thymoma.
Benveniste MF, Rosado-de-Christenson ML, Sabloff BS, Moran CA, Swisher SG, Marom EM
Radiographics 2011 Nov-Dec;31(7):1847-61; discussion 1861-3. doi: 10.1148/rg.317115505. PMID: 22084174

Recent clinical studies

Etiology

Fetal upper mediastinum - normal and abnormal findings in obstetric ultrasound screening.
Wojtowicz A, Huras H
Ginekol Pol 2020;91(10):620-628. doi: 10.5603/GP.a2020.0092. PMID: 33184831
Imaging cardiac innervation in amyloidosis.
Slart RHJA, Glaudemans AWJM, Hazenberg BPC, Noordzij W
J Nucl Cardiol 2019 Feb;26(1):174-187. Epub 2017 Sep 8 doi: 10.1007/s12350-017-1059-9. PMID: 28887775Free PMC Article
ITMIG Classification of Mediastinal Compartments and Multidisciplinary Approach to Mediastinal Masses.
Carter BW, Benveniste MF, Madan R, Godoy MC, de Groot PM, Truong MT, Rosado-de-Christenson ML, Marom EM
Radiographics 2017 Mar-Apr;37(2):413-436. Epub 2017 Jan 27 doi: 10.1148/rg.2017160095. PMID: 28129068
Neonatal teratomas.
Lakhoo K
Early Hum Dev 2010 Oct;86(10):643-7. Epub 2010 Sep 29 doi: 10.1016/j.earlhumdev.2010.08.016. PMID: 20884137
Tuberculosis and mediastinoscopy.
Cameron EW
Thorax 1978 Feb;33(1):117-20. doi: 10.1136/thx.33.1.117. PMID: 417418Free PMC Article

Diagnosis

ITMIG Classification of Mediastinal Compartments and Multidisciplinary Approach to Mediastinal Masses.
Carter BW, Benveniste MF, Madan R, Godoy MC, de Groot PM, Truong MT, Rosado-de-Christenson ML, Marom EM
Radiographics 2017 Mar-Apr;37(2):413-436. Epub 2017 Jan 27 doi: 10.1148/rg.2017160095. PMID: 28129068
Neonatal teratomas.
Lakhoo K
Early Hum Dev 2010 Oct;86(10):643-7. Epub 2010 Sep 29 doi: 10.1016/j.earlhumdev.2010.08.016. PMID: 20884137
Congenital anomalies of the tracheobronchial tree, lung, and mediastinum: embryology, radiology, and pathology.
Berrocal T, Madrid C, Novo S, Gutiérrez J, Arjonilla A, Gómez-León N
Radiographics 2004 Jan-Feb;24(1):e17. Epub 2003 Nov 10 doi: 10.1148/rg.e17. PMID: 14610245
Fibrosing mediastinitis.
Rossi SE, McAdams HP, Rosado-de-Christenson ML, Franks TJ, Galvin JR
Radiographics 2001 May-Jun;21(3):737-57. doi: 10.1148/radiographics.21.3.g01ma17737. PMID: 11353121
Tuberculosis and mediastinoscopy.
Cameron EW
Thorax 1978 Feb;33(1):117-20. doi: 10.1136/thx.33.1.117. PMID: 417418Free PMC Article

Therapy

T-cell lymphoma secondary to checkpoint inhibitor therapy.
Anand K, Ensor J, Pingali SR, Hwu P, Duvic M, Chiang S, Miranda R, Zu Y, Iyer S
J Immunother Cancer 2020 Feb;8(1) doi: 10.1136/jitc-2019-000104. PMID: 32114498Free PMC Article
Methods for staging non-small cell lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines.
Silvestri GA, Gonzalez AV, Jantz MA, Margolis ML, Gould MK, Tanoue LT, Harris LJ, Detterbeck FC
Chest 2013 May;143(5 Suppl):e211S-e250S. doi: 10.1378/chest.12-2355. PMID: 23649440
Unilateral hyperlucent lung in children.
Wasilewska E, Lee EY, Eisenberg RL
AJR Am J Roentgenol 2012 May;198(5):W400-14. doi: 10.2214/AJR.11.7028. PMID: 22528920
Chest reconstruction: I. Anterior and anterolateral chest wall and wounds affecting respiratory function.
Netscher DT, Baumholtz MA
Plast Reconstr Surg 2009 Nov;124(5):240e-252e. doi: 10.1097/PRS.0b013e3181b98c9c. PMID: 20009799
Complications of mediastinal neural tumours.
Parish C
Thorax 1971 Jul;26(4):392-5. doi: 10.1136/thx.26.4.392. PMID: 4327710Free PMC Article

Prognosis

Imaging cardiac innervation in amyloidosis.
Slart RHJA, Glaudemans AWJM, Hazenberg BPC, Noordzij W
J Nucl Cardiol 2019 Feb;26(1):174-187. Epub 2017 Sep 8 doi: 10.1007/s12350-017-1059-9. PMID: 28887775Free PMC Article
Amyloidosis: Modern Cross-sectional Imaging.
Czeyda-Pommersheim F, Hwang M, Chen SS, Strollo D, Fuhrman C, Bhalla S
Radiographics 2015 Sep-Oct;35(5):1381-92. Epub 2015 Jul 31 doi: 10.1148/rg.2015140179. PMID: 26230754
Methods for staging non-small cell lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines.
Silvestri GA, Gonzalez AV, Jantz MA, Margolis ML, Gould MK, Tanoue LT, Harris LJ, Detterbeck FC
Chest 2013 May;143(5 Suppl):e211S-e250S. doi: 10.1378/chest.12-2355. PMID: 23649440
Fibrosing mediastinitis.
Rossi SE, McAdams HP, Rosado-de-Christenson ML, Franks TJ, Galvin JR
Radiographics 2001 May-Jun;21(3):737-57. doi: 10.1148/radiographics.21.3.g01ma17737. PMID: 11353121
Thymomas.
LeGolvan DP, Abell MR
Cancer 1977 May;39(5):2142-57. doi: 10.1002/1097-0142(197705)39:5<2142::aid-cncr2820390531>3.0.co;2-q. PMID: 558046

Clinical prediction guides

EBUS-TBNA in Extrathoracic Malignancies: Diagnostic and Prognostic Implications.
Martin-Deleon R, Solarat B, Moisés J, Lucena CM, Fontana A, Marrades RM, Agustí C
Lung 2022 Dec;200(6):747-753. Epub 2022 Oct 30 doi: 10.1007/s00408-022-00584-5. PMID: 36309894
Autonomic disorders and myocardial 123I-metaiodobenzylguanidine scintigraphy in Huntington's disease.
Assante R, Salvatore E, Nappi C, Peluso S, De Simini G, Di Maio L, Palmieri GR, Ferrara IP, Roca A, De Michele G, Cuocolo A, Pappatà S, De Rosa A
J Nucl Cardiol 2022 Apr;29(2):642-648. Epub 2020 Aug 16 doi: 10.1007/s12350-020-02299-7. PMID: 32803674Free PMC Article
Adult T-cell leukemia.
Aoki J, Sato N, Oya N, Inoue T, Endo K
Semin Musculoskelet Radiol 2001 Jun;5(2):95-8. doi: 10.1055/s-2001-15659. PMID: 11500147
Tuberculosis and mediastinoscopy.
Cameron EW
Thorax 1978 Feb;33(1):117-20. doi: 10.1136/thx.33.1.117. PMID: 417418Free PMC Article
Thymomas.
LeGolvan DP, Abell MR
Cancer 1977 May;39(5):2142-57. doi: 10.1002/1097-0142(197705)39:5<2142::aid-cncr2820390531>3.0.co;2-q. PMID: 558046

Recent systematic reviews

Right or left thoracotomy for esophageal atresia and right aortic arch? Systematic review and surgicoanatomic justification.
Mentessidou A, Avgerinos I, Avgerinos N, Skandalakis PN, Mirilas P
J Pediatr Surg 2018 Nov;53(11):2128-2135. Epub 2018 Jun 19 doi: 10.1016/j.jpedsurg.2018.06.015. PMID: 30318282
Endobronchial Ultrasound-guided Aspiration of an Endotracheal Bronchogenic Cyst: Case Report and Systematic Review of the Literature.
Maturu VN, Dhooria S, Agarwal R, Behera D
J Bronchology Interv Pulmonol 2016 Apr;23(2):163-7. doi: 10.1097/LBR.0000000000000195. PMID: 26905441
Efficacy and Safety of Transbronchial Needle Aspiration in Diagnosis and Treatment of Mediastinal Bronchogenic Cysts: Systematic Review of Case Reports.
Maturu VN, Dhooria S, Agarwal R
J Bronchology Interv Pulmonol 2015 Jul;22(3):195-203. doi: 10.1097/LBR.0000000000000174. PMID: 26165889

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