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Elevated urinary carboxylic acid

MedGen UID:
868022
Concept ID:
C4022413
Finding
HPO: HP:0040156

Definition

An increased amount of carboxylic acid in the urine. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVElevated urinary carboxylic acid

Professional guidelines

PubMed

Wang B, Bonkovsky HL, Lim JK, Balwani M
Gastroenterology 2023 Mar;164(3):484-491. Epub 2023 Jan 13 doi: 10.1053/j.gastro.2022.11.034. PMID: 36642627Free PMC Article
Hoppe B, Martin-Higueras C
Drugs 2022 Jul;82(10):1077-1094. Epub 2022 Jul 2 doi: 10.1007/s40265-022-01735-x. PMID: 35779234Free PMC Article
Seiler N
Curr Drug Targets 2000 Sep;1(2):119-53. doi: 10.2174/1389450003349254. PMID: 11465067

Recent clinical studies

Etiology

Krečak I, Babić G, Skelin M
Acta Dermatovenerol Croat 2022 Jul;30(1):59-60. PMID: 36153722
Samson ME, Yeung LF, Rose CE, Qi YP, Taylor CA, Crider KS
Am J Clin Nutr 2022 Jul 6;116(1):74-85. doi: 10.1093/ajcn/nqac065. PMID: 35584808Free PMC Article
Rimer JD, Sakhaee K, Maalouf NM
Curr Opin Nephrol Hypertens 2019 Mar;28(2):130-139. doi: 10.1097/MNH.0000000000000474. PMID: 30531474
Hubers SA, Brown NJ
Circulation 2016 Mar 15;133(11):1115-24. doi: 10.1161/CIRCULATIONAHA.115.018622. PMID: 26976916Free PMC Article
Ayach T, Nappo RW, Paugh-Miller JL, Ross EA
Eur J Intern Med 2015 Mar;26(2):106-11. Epub 2015 Feb 17 doi: 10.1016/j.ejim.2015.01.010. PMID: 25698564

Diagnosis

Morava E, Oglesbee D
Handb Clin Neurol 2023;194:167-172. doi: 10.1016/B978-0-12-821751-1.00012-9. PMID: 36813311
Wang B, Bonkovsky HL, Lim JK, Balwani M
Gastroenterology 2023 Mar;164(3):484-491. Epub 2023 Jan 13 doi: 10.1053/j.gastro.2022.11.034. PMID: 36642627Free PMC Article
Krečak I, Babić G, Skelin M
Acta Dermatovenerol Croat 2022 Jul;30(1):59-60. PMID: 36153722
Stölzel U, Doss MO, Schuppan D
Gastroenterology 2019 Aug;157(2):365-381.e4. Epub 2019 May 11 doi: 10.1053/j.gastro.2019.04.050. PMID: 31085196
Hubers SA, Brown NJ
Circulation 2016 Mar 15;133(11):1115-24. doi: 10.1161/CIRCULATIONAHA.115.018622. PMID: 26976916Free PMC Article

Therapy

Ermer T, Nazzal L, Tio MC, Waikar S, Aronson PS, Knauf F
Nat Rev Nephrol 2023 Feb;19(2):123-138. Epub 2022 Nov 3 doi: 10.1038/s41581-022-00643-3. PMID: 36329260Free PMC Article
Krečak I, Babić G, Skelin M
Acta Dermatovenerol Croat 2022 Jul;30(1):59-60. PMID: 36153722
Rimer JD, Sakhaee K, Maalouf NM
Curr Opin Nephrol Hypertens 2019 Mar;28(2):130-139. doi: 10.1097/MNH.0000000000000474. PMID: 30531474
Hubers SA, Brown NJ
Circulation 2016 Mar 15;133(11):1115-24. doi: 10.1161/CIRCULATIONAHA.115.018622. PMID: 26976916Free PMC Article
Levine M, Conry-Cantilena C, Wang Y, Welch RW, Washko PW, Dhariwal KR, Park JB, Lazarev A, Graumlich JF, King J, Cantilena LR
Proc Natl Acad Sci U S A 1996 Apr 16;93(8):3704-9. doi: 10.1073/pnas.93.8.3704. PMID: 8623000Free PMC Article

Prognosis

Gibson JC, Marro L, Brandow D, Remedios L, Fisher M, Borghese MM, Kieliszkiewicz K, Lukina AO, Irwin K
Int J Hyg Environ Health 2023 Mar;248:114093. Epub 2022 Dec 9 doi: 10.1016/j.ijheh.2022.114093. PMID: 36508962
Goetz M, Schröter J, Dattner T, Brennenstuhl H, Lenz D, Opladen T, Hörster F, Okun JG, Hoffmann GF, Kölker S, Staufner C
Mol Genet Metab 2022 Sep-Oct;137(1-2):18-25. Epub 2022 Jul 11 doi: 10.1016/j.ymgme.2022.07.007. PMID: 35868242
Yang K, Deng HB, Man AWC, Song E, Zhang J, Luo C, Cheung BMY, Yuen KY, Jensen PS, Irmukhamedov A, Elie AGIM, Vanhoutte PM, Xu A, De Mey JGR, Wang Y
ESC Heart Fail 2017 Nov;4(4):563-575. Epub 2017 Jun 27 doi: 10.1002/ehf2.12183. PMID: 29154418Free PMC Article
Hubers SA, Brown NJ
Circulation 2016 Mar 15;133(11):1115-24. doi: 10.1161/CIRCULATIONAHA.115.018622. PMID: 26976916Free PMC Article
Griffith DP
Urol Res 1979 Sep;7(3):215-21. doi: 10.1007/BF00257208. PMID: 388798

Clinical prediction guides

Morava E, Oglesbee D
Handb Clin Neurol 2023;194:167-172. doi: 10.1016/B978-0-12-821751-1.00012-9. PMID: 36813311
Gupta M, Gallante B, Bamberger JN, Khusid JA, Parkhomenko E, Chandhoke R, Capodice J, Atallah W
J Endourol 2021 Dec;35(12):1844-1851. doi: 10.1089/end.2021.0122. PMID: 34254834
Balwani M, Sardh E, Ventura P, Peiró PA, Rees DC, Stölzel U, Bissell DM, Bonkovsky HL, Windyga J, Anderson KE, Parker C, Silver SM, Keel SB, Wang JD, Stein PE, Harper P, Vassiliou D, Wang B, Phillips J, Ivanova A, Langendonk JG, Kauppinen R, Minder E, Horie Y, Penz C, Chen J, Liu S, Ko JJ, Sweetser MT, Garg P, Vaishnaw A, Kim JB, Simon AR, Gouya L; ENVISION Investigators
N Engl J Med 2020 Jun 11;382(24):2289-2301. doi: 10.1056/NEJMoa1913147. PMID: 32521132
Shim K, Gulhar R, Jialal I
J Diabetes Complications 2019 Mar;33(3):212-216. Epub 2018 Dec 10 doi: 10.1016/j.jdiacomp.2018.12.002. PMID: 30611573
Xia B, Zhu Q, Zhao Y, Ge W, Zhao Y, Song Q, Zhou Y, Shi H, Zhang Y
Environ Int 2018 Dec;121(Pt 1):159-168. Epub 2018 Sep 9 doi: 10.1016/j.envint.2018.09.001. PMID: 30208345

Recent systematic reviews

Mostafa N, Phan K, Smith S
J Dermatolog Treat 2022 Feb;33(1):369-372. Epub 2020 Apr 23 doi: 10.1080/09546634.2020.1755416. PMID: 32281437
Zhang H, Gao F, Ben Y, Su Y
Environ Pollut 2020 Dec;267:115446. Epub 2020 Aug 22 doi: 10.1016/j.envpol.2020.115446. PMID: 32866875
Song Y, Chou EL, Baecker A, You NC, Song Y, Sun Q, Liu S
J Diabetes 2016 Jul;8(4):516-32. Epub 2015 Sep 1 doi: 10.1111/1753-0407.12325. PMID: 26119400
He D, Xu Z, Dong S, Zhang H, Zhou H, Wang L, Zhang S
Cochrane Database Syst Rev 2012 Dec 12;12:CD009882. doi: 10.1002/14651858.CD009882.pub2. PMID: 23235682

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