U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Toenail onycholysis

MedGen UID:
868085
Concept ID:
C4022476
Disease or Syndrome; Finding
Synonyms: Detachment of toenails; Onycholysis of toenails
 
HPO: HP:0040040

Definition

Painless and spontaneous separation of a toenail from the nail bed. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVToenail onycholysis

Professional guidelines

PubMed

Lee DK, Lipner SR
Ann Med 2022 Dec;54(1):694-712. doi: 10.1080/07853890.2022.2044511. PMID: 35238267Free PMC Article
Filisio F, Busch S, Wickramage DJH, Hill R, Kabadi S, Van Pelt CL, Vlahovic TC
Clin Podiatr Med Surg 2021 Oct;38(4):521-527. doi: 10.1016/j.cpm.2021.06.001. PMID: 34538429
Geizhals S, Lipner SR
Am J Clin Dermatol 2020 Apr;21(2):297-302. doi: 10.1007/s40257-019-00476-0. PMID: 31595433

Recent clinical studies

Etiology

Wang S, Zhu J, Wang P, Dong J, Li Y, Shi D, Wang H, Huang X, Zhang X, Yu B, Yang Z, Chen R, Wang X, Li F, Bian K, Huo Y, Yu N, Li C, Xia X, Lu J, Li J, Lu Y, Xu Y, Ding Y, Li Y, Kang X, Li R
J Eur Acad Dermatol Venereol 2024 Mar;38(3):549-556. Epub 2023 Dec 15 doi: 10.1111/jdv.19684. PMID: 38100231
Canal-García E, Bosch-Amate X, Belinchón I, Puig L
Actas Dermosifiliogr 2022 May;113(5):481-490. Epub 2022 Feb 2 doi: 10.1016/j.ad.2022.01.006. PMID: 35697407
Dinani N, George S
Clin Exp Dermatol 2019 Aug;44(6):599-605. Epub 2019 Feb 21 doi: 10.1111/ced.13929. PMID: 30793352
Piraccini BM, Alessandrini A
Clin Dermatol 2013 Sep-Oct;31(5):618-26. doi: 10.1016/j.clindermatol.2013.06.013. PMID: 24079591
Shemer A, Daniel CR 3rd
Clin Dermatol 2013 Sep-Oct;31(5):578-86. doi: 10.1016/j.clindermatol.2013.06.015. PMID: 24079587

Diagnosis

Canal-García E, Bosch-Amate X, Belinchón I, Puig L
Actas Dermosifiliogr 2022 May;113(5):481-490. Epub 2022 Feb 2 doi: 10.1016/j.ad.2022.01.006. PMID: 35697407
Lee DK, Lipner SR
Ann Med 2022 Dec;54(1):694-712. doi: 10.1080/07853890.2022.2044511. PMID: 35238267Free PMC Article
Starace M, Alessandrini A, Piraccini BM
Dermatol Clin 2021 Apr;39(2):293-304. Epub 2021 Feb 10 doi: 10.1016/j.det.2020.12.008. PMID: 33745641
Leung AKC, Lam JM, Leong KF, Hon KL, Barankin B, Leung AAM, Wong AHC
Recent Pat Inflamm Allergy Drug Discov 2020;14(1):32-45. doi: 10.2174/1872213X13666191026090713. PMID: 31738146Free PMC Article
Lacouture M, Sibaud V
Am J Clin Dermatol 2018 Nov;19(Suppl 1):31-39. doi: 10.1007/s40257-018-0384-3. PMID: 30374901Free PMC Article

Therapy

Gupta AK, Talukder M
Am J Clin Dermatol 2022 Mar;23(2):207-218. Epub 2021 Dec 13 doi: 10.1007/s40257-021-00660-1. PMID: 34902110
Leung AKC, Lam JM, Leong KF, Hon KL, Barankin B, Leung AAM, Wong AHC
Recent Pat Inflamm Allergy Drug Discov 2020;14(1):32-45. doi: 10.2174/1872213X13666191026090713. PMID: 31738146Free PMC Article
Dinani N, George S
Clin Exp Dermatol 2019 Aug;44(6):599-605. Epub 2019 Feb 21 doi: 10.1111/ced.13929. PMID: 30793352
Lacouture M, Sibaud V
Am J Clin Dermatol 2018 Nov;19(Suppl 1):31-39. doi: 10.1007/s40257-018-0384-3. PMID: 30374901Free PMC Article
Piraccini BM, Alessandrini A
Clin Dermatol 2013 Sep-Oct;31(5):618-26. doi: 10.1016/j.clindermatol.2013.06.013. PMID: 24079591

Prognosis

Grover C, Jayasree P, Kaliyadan F
Int J Dermatol 2021 Jun;60(6):693-702. Epub 2020 Dec 17 doi: 10.1111/ijd.15358. PMID: 33332614
Chelidze K, Lipner SR
Int J Dermatol 2018 Jul;57(7):776-783. Epub 2018 Jan 10 doi: 10.1111/ijd.13866. PMID: 29318582
Baran R
Dermatology 2010;221 Suppl 1:1-5. Epub 2010 Aug 9 doi: 10.1159/000316169. PMID: 20733309
Scher RK, Tavakkol A, Sigurgeirsson B, Hay RJ, Joseph WS, Tosti A, Fleckman P, Ghannoum M, Armstrong DG, Markinson BC, Elewski BE
J Am Acad Dermatol 2007 Jun;56(6):939-44. Epub 2007 Feb 16 doi: 10.1016/j.jaad.2006.12.019. PMID: 17307276
Sharquie IK, Al-Faham M, Karhoot JM, Sharquie KE, Al-Waiz MM, Al-Douri WS
Saudi Med J 2005 Sep;26(9):1439-41. PMID: 16155665

Clinical prediction guides

Leung AKC, Lam JM, Leong KF, Hon KL, Barankin B, Leung AAM, Wong AHC
Recent Pat Inflamm Allergy Drug Discov 2020;14(1):32-45. doi: 10.2174/1872213X13666191026090713. PMID: 31738146Free PMC Article
Lacouture M, Sibaud V
Am J Clin Dermatol 2018 Nov;19(Suppl 1):31-39. doi: 10.1007/s40257-018-0384-3. PMID: 30374901Free PMC Article
Piraccini BM, Alessandrini A
Clin Dermatol 2013 Sep-Oct;31(5):618-26. doi: 10.1016/j.clindermatol.2013.06.013. PMID: 24079591
Piraccini BM, Iorizzo M, Tosti A
Am J Clin Dermatol 2003;4(1):31-7. doi: 10.2165/00128071-200304010-00004. PMID: 12477371
Baran R, Juhlin L
Photodermatol Photoimmunol Photomed 2002 Aug;18(4):202-7. doi: 10.1034/j.1600-0781.2002.00760.x. PMID: 12390677

Recent systematic reviews

Golińska J, Sar-Pomian M, Rudnicka L
J Eur Acad Dermatol Venereol 2019 Apr;33(4):648-660. doi: 10.1111/jdv.15344. PMID: 30422349
Rouzaud M, Sevrain M, Villani AP, Barnetche T, Paul C, Richard MA, Jullien D, Misery L, Le Maître M, Aractingi S, Aubin F, Joly P, Cantagrel A, Ortonne JP, Beylot-Barry M
J Eur Acad Dermatol Venereol 2014 Aug;28 Suppl 5:17-26. doi: 10.1111/jdv.12562. PMID: 24985559

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...