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Abnormality of the anterior commissure

MedGen UID:
868134
•Concept ID:
C4022525
•
Anatomical Abnormality
HPO: HP:0030301

Definition

An anomaly of the anterior commissure, a bundle of nerve fibers that connect the two cerebral hemispheres across the midline. The anterior commissure plays a role in pain sensation and contains decussating fibers from the olfactory tracts. [from HPO]

Conditions with this feature

Gaze palsy, familial horizontal, with progressive scoliosis, 2
MedGen UID:
1393733
•Concept ID:
C4479640
•
Disease or Syndrome
See: Condition Record
Gaze palsy, familial horizontal, with progressive scoliosis, 2

Professional guidelines

PubMed

Surgical Treatment Modalities for Iatrogenic Anterior Glottic Stenosis.
Cao Y, Sun G
Ann Otol Rhinol Laryngol 2018 Dec;127(12):946-952. Epub 2018 Sep 29 doi: 10.1177/0003489418803651. PMID: 30269514
Masses and malformations of the third ventricle: normal anatomic relationships and differential diagnoses.
Glastonbury CM, Osborn AG, Salzman KL
Radiographics 2011 Nov-Dec;31(7):1889-905. doi: 10.1148/rg.317115083. PMID: 22084178
Frontal white matter microstructure and treatment response of late-life depression: a preliminary study.
Alexopoulos GS, Kiosses DN, Choi SJ, Murphy CF, Lim KO
Am J Psychiatry 2002 Nov;159(11):1929-32. doi: 10.1176/appi.ajp.159.11.1929. PMID: 12411231

Recent clinical studies

Etiology

The spectrum of neurodevelopmental, neuromuscular and neurodegenerative disorders due to defective autophagy.
Deneubourg C, Ramm M, Smith LJ, Baron O, Singh K, Byrne SC, Duchen MR, Gautel M, Eskelinen EL, Fanto M, Jungbluth H
Autophagy 2022 Mar;18(3):496-517. Epub 2021 Aug 19 doi: 10.1080/15548627.2021.1943177. PMID: 34130600Free PMC Article
A Method for Reconstruction of Anterior Commissure Glottal Webs With Endoscopic Fibro-Mucosal Flaps.
Zeitels SM, Hillman RE
Ann Otol Rhinol Laryngol 2019 Mar;128(3_suppl):82S-93S. doi: 10.1177/0003489418820031. PMID: 30843433
Structure and function of the tricuspid and bicuspid regurgitant aortic valve: an echocardiographic study.
Rönnerfalk M, Tamás É
Interact Cardiovasc Thorac Surg 2015 Jul;21(1):71-6. Epub 2015 Apr 2 doi: 10.1093/icvts/ivv072. PMID: 25840434
Complexity stratification of the arterial switch operation: a second learning curve.
Lacour-Gayet F
Cardiol Young 2012 Dec;22(6):739-44. doi: 10.1017/S1047951112001564. PMID: 23331596
Epilepsy.
Koepp MJ, Duncan JS
Curr Opin Neurol 2004 Aug;17(4):467-74. doi: 10.1097/01.wco.0000137539.91738.2b. PMID: 15247544

Diagnosis

The spectrum of neurodevelopmental, neuromuscular and neurodegenerative disorders due to defective autophagy.
Deneubourg C, Ramm M, Smith LJ, Baron O, Singh K, Byrne SC, Duchen MR, Gautel M, Eskelinen EL, Fanto M, Jungbluth H
Autophagy 2022 Mar;18(3):496-517. Epub 2021 Aug 19 doi: 10.1080/15548627.2021.1943177. PMID: 34130600Free PMC Article
White-matter commissures: a clinically focused anatomical review.
Lavrador JP, Ferreira V, Lourenço M, Alexandre I, Rocha M, Oliveira E, Kailaya-Vasan A, Neto L
Surg Radiol Anat 2019 Jun;41(6):613-624. Epub 2019 May 22 doi: 10.1007/s00276-019-02218-7. PMID: 31119409
A Method for Reconstruction of Anterior Commissure Glottal Webs With Endoscopic Fibro-Mucosal Flaps.
Zeitels SM, Hillman RE
Ann Otol Rhinol Laryngol 2019 Mar;128(3_suppl):82S-93S. doi: 10.1177/0003489418820031. PMID: 30843433
The anterior laryngeal webs.
Nicollas R, Triglia JM
Otolaryngol Clin North Am 2008 Oct;41(5):877-88, viii. doi: 10.1016/j.otc.2008.04.008. PMID: 18775339
Epilepsy.
Koepp MJ, Duncan JS
Curr Opin Neurol 2004 Aug;17(4):467-74. doi: 10.1097/01.wco.0000137539.91738.2b. PMID: 15247544

Therapy

Modeling of the Tricuspid Valve and Right Ventricle in Hypoplastic Left Heart Syndrome With a Fontan Circulation.
Nam HH, Flynn M, Lasso A, Herz C, Sabin P, Wang Y, Cianciulli A, Vigil C, Huang J, Vicory J, Paniagua B, Allemang D, Goldberg DJ, Nuri M, Cohen MS, Fichtinger G, Jolley MA
Circ Cardiovasc Imaging 2023 Mar;16(3):e014671. Epub 2023 Mar 3 doi: 10.1161/CIRCIMAGING.122.014671. PMID: 36866669Free PMC Article
Specific tractography differences in autism compared to developmental coordination disorder.
Kilroy E, Gerbella M, Cao L, Molfese P, Butera C, Harrison L, Jayashankar A, Rizzolatti G, Aziz-Zadeh L
Sci Rep 2022 Nov 14;12(1):19246. doi: 10.1038/s41598-022-21538-0. PMID: 36376319Free PMC Article
Neuronal Cell Mechanisms of Pain.
Nwonu CNS
West Afr J Med 2022 Oct 20;39(10):1075-1983. PMID: 36260866
Surgical Treatment Modalities for Iatrogenic Anterior Glottic Stenosis.
Cao Y, Sun G
Ann Otol Rhinol Laryngol 2018 Dec;127(12):946-952. Epub 2018 Sep 29 doi: 10.1177/0003489418803651. PMID: 30269514
Pontine encephalocele and abnormalities of the posterior fossa following transclival endoscopic endonasal surgery.
Koutourousiou M, Filho FV, Costacou T, Fernandez-Miranda JC, Wang EW, Snyderman CH, Rothfus WE, Gardner PA
J Neurosurg 2014 Aug;121(2):359-66. Epub 2014 Feb 7 doi: 10.3171/2013.12.JNS13756. PMID: 24506240

Prognosis

The spectrum of neurodevelopmental, neuromuscular and neurodegenerative disorders due to defective autophagy.
Deneubourg C, Ramm M, Smith LJ, Baron O, Singh K, Byrne SC, Duchen MR, Gautel M, Eskelinen EL, Fanto M, Jungbluth H
Autophagy 2022 Mar;18(3):496-517. Epub 2021 Aug 19 doi: 10.1080/15548627.2021.1943177. PMID: 34130600Free PMC Article
The middle interhemispheric variant of holoprosencephaly: magnetic resonance and diffusion tensor imaging findings.
Bulakbasi N, Cancuri O, Kocaoğlu M
Br J Radiol 2016 Jul;89(1063):20160115. Epub 2016 Apr 19 doi: 10.1259/bjr.20160115. PMID: 27089898Free PMC Article
Structure and function of the tricuspid and bicuspid regurgitant aortic valve: an echocardiographic study.
Rönnerfalk M, Tamás É
Interact Cardiovasc Thorac Surg 2015 Jul;21(1):71-6. Epub 2015 Apr 2 doi: 10.1093/icvts/ivv072. PMID: 25840434
Complexity stratification of the arterial switch operation: a second learning curve.
Lacour-Gayet F
Cardiol Young 2012 Dec;22(6):739-44. doi: 10.1017/S1047951112001564. PMID: 23331596
Aortic intramural course of the left coronary artery in dextro-transposition of the great arteries.
Sim EK, van Son JA, Julsrud PR, Puga FJ
Ann Thorac Surg 1994 Feb;57(2):458-60. doi: 10.1016/0003-4975(94)91017-0. PMID: 8311612

Clinical prediction guides

A Method for Reconstruction of Anterior Commissure Glottal Webs With Endoscopic Fibro-Mucosal Flaps.
Zeitels SM, Hillman RE
Ann Otol Rhinol Laryngol 2019 Mar;128(3_suppl):82S-93S. doi: 10.1177/0003489418820031. PMID: 30843433
Tubulin genes and malformations of cortical development.
Romaniello R, Arrigoni F, Fry AE, Bassi MT, Rees MI, Borgatti R, Pilz DT, Cushion TD
Eur J Med Genet 2018 Dec;61(12):744-754. Epub 2018 Jul 17 doi: 10.1016/j.ejmg.2018.07.012. PMID: 30016746
Mutations in α- and β-tubulin encoding genes: implications in brain malformations.
Romaniello R, Arrigoni F, Bassi MT, Borgatti R
Brain Dev 2015 Mar;37(3):273-80. Epub 2014 Jul 5 doi: 10.1016/j.braindev.2014.06.002. PMID: 25008804
Complexity stratification of the arterial switch operation: a second learning curve.
Lacour-Gayet F
Cardiol Young 2012 Dec;22(6):739-44. doi: 10.1017/S1047951112001564. PMID: 23331596
Origins of the coronary arteries and their significance.
Joshi SD, Joshi SS, Athavale SA
Clinics (Sao Paulo) 2010;65(1):79-84. doi: 10.1590/S1807-59322010000100012. PMID: 20126349Free PMC Article

Recent systematic reviews

Brain functional connectivity in individuals with callosotomy and agenesis of the corpus callosum: A systematic review.
Mancuso L, Uddin LQ, Nani A, Costa T, Cauda F
Neurosci Biobehav Rev 2019 Oct;105:231-248. Epub 2019 Aug 11 doi: 10.1016/j.neubiorev.2019.07.004. PMID: 31412269
Neurobiological underpinnings of bipolar disorder focusing on findings of diffusion tensor imaging: a systematic review.
Duarte JA, de Araújo E Silva JQ, Goldani AA, Massuda R, Gama CS
Braz J Psychiatry 2016 Mar 22;38(2):167-75. doi: 10.1590/1516-4446-2015-1793. PMID: 27007148Free PMC Article

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