U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal sperm tail morphology

MedGen UID:
868305
Concept ID:
C4022699
Finding
Synonym: Sperm tail anomaly
 
HPO: HP:0012868

Definition

A structural abnormality of the sperm tail. [from HPO]

Conditions with this feature

Deafness-infertility syndrome
MedGen UID:
370197
Concept ID:
C1970187
Disease or Syndrome
CATSPER-related male infertility results from abnormalities in sperm and can be either CATSPER-related nonsyndromic male infertility (NSMI) or the deafness-infertility syndrome (DIS) when associated with non-progressive prelingual sensorineural hearing loss. Males with NSMI have infertility while females have no symptoms. Males with DIS have both infertility and hearing loss, while females have only hearing loss. Routine semen analysis typically identifies abnormalities in sperm number, morphology, and motility. Otologic examination and audiologic assessment can identify hearing loss.

Professional guidelines

PubMed

Lasiene K, Gedrimas V, Vitkus A, Glinskyte S, Lasys V, Valanciute A, Sienkiewicz W
Pol J Vet Sci 2013;16(4):773-85. doi: 10.2478/pjvs-2013-0112. PMID: 24597318
Klysik M
Pathol Res Pract 2008;204(2):77-88. doi: 10.1016/j.prp.2007.10.013. PMID: 18312782
Sedor JF, Hirsch IH
Fertil Steril 1995 May;63(5):1125-7. doi: 10.1016/s0015-0282(16)57561-x. PMID: 7720930

Recent clinical studies

Etiology

Kleshchev M, Osadchuk L, Osadchuk A
Front Biosci (Schol Ed) 2023 Sep 27;15(3):12. doi: 10.31083/j.fbs1503012. PMID: 37806952
Oud MS, Houston BJ, Volozonoka L, Mastrorosa FK, Holt GS, Alobaidi BKS, deVries PF, Astuti G, Ramos L, Mclachlan RI, O'Bryan MK, Veltman JA, Chemes HE, Sheth H
Hum Reprod 2021 Aug 18;36(9):2597-2611. doi: 10.1093/humrep/deab099. PMID: 34089056Free PMC Article
Morini D, Spaggiari G, Daolio J, Melli B, Nicoli A, De Feo G, Valli B, Viola D, Garganigo S, Magnani E, Pilia A, Polese A, Colla R, Simoni M, Aguzzoli L, Villani MT, Santi D
Andrology 2021 Jul;9(4):1176-1184. Epub 2021 May 6 doi: 10.1111/andr.13012. PMID: 33825345Free PMC Article
Liu C, Tu C, Wang L, Wu H, Houston BJ, Mastrorosa FK, Zhang W, Shen Y, Wang J, Tian S, Meng L, Cong J, Yang S, Jiang Y, Tang S, Zeng Y, Lv M, Lin G, Li J, Saiyin H, He X, Jin L, Touré A, Ray PF, Veltman JA, Shi Q, O'Bryan MK, Cao Y, Tan YQ, Zhang F
Am J Hum Genet 2021 Feb 4;108(2):309-323. Epub 2021 Jan 19 doi: 10.1016/j.ajhg.2021.01.002. PMID: 33472045Free PMC Article
Coutton C, Escoffier J, Martinez G, Arnoult C, Ray PF
Hum Reprod Update 2015 Jul-Aug;21(4):455-85. Epub 2015 Apr 17 doi: 10.1093/humupd/dmv020. PMID: 25888788

Diagnosis

Tan C, Meng L, Lv M, He X, Sha Y, Tang D, Tan Y, Hu T, He W, Tu C, Nie H, Zhang H, Du J, Lu G, Fan LQ, Cao Y, Lin G, Tan YQ
Am J Hum Genet 2022 Jan 6;109(1):157-171. Epub 2021 Dec 20 doi: 10.1016/j.ajhg.2021.11.022. PMID: 34932939Free PMC Article
Kumar N, Singh AK
Biol Reprod 2021 Mar 11;104(3):508-520. doi: 10.1093/biolre/ioaa213. PMID: 33238303
Pleuger C, Lehti MS, Dunleavy JE, Fietz D, O'Bryan MK
Hum Reprod Update 2020 Jun 18;26(4):474-500. doi: 10.1093/humupd/dmaa004. PMID: 32318721
Pereira R, Sá R, Barros A, Sousa M
Asian J Androl 2017 Jan-Feb;19(1):5-14. doi: 10.4103/1008-682X.167716. PMID: 26680031Free PMC Article
Coutton C, Escoffier J, Martinez G, Arnoult C, Ray PF
Hum Reprod Update 2015 Jul-Aug;21(4):455-85. Epub 2015 Apr 17 doi: 10.1093/humupd/dmv020. PMID: 25888788

Therapy

Kleshchev M, Osadchuk L, Osadchuk A
Front Biosci (Schol Ed) 2023 Sep 27;15(3):12. doi: 10.31083/j.fbs1503012. PMID: 37806952
Adamczak R, Ukleja-Sokołowska N, Pasińska M, Zielińska J, Leśny M, Dubiel M
Int J Immunopathol Pharmacol 2022 Jan-Dec;36:20587384211066718. doi: 10.1177/20587384211066718. PMID: 34984934Free PMC Article
Pereira R, Sá R, Barros A, Sousa M
Asian J Androl 2017 Jan-Feb;19(1):5-14. doi: 10.4103/1008-682X.167716. PMID: 26680031Free PMC Article
Auger J, Jouannet P, Eustache F
Hum Reprod 2016 Jan;31(1):10-23. Epub 2015 Oct 14 doi: 10.1093/humrep/dev251. PMID: 26472152
Afzelius BA
CRC Crit Rev Biochem 1985;19(1):63-87. doi: 10.3109/10409238509086788. PMID: 3907978

Prognosis

Nassir M, Levi M, Dardikman-Yoffe G, Mirsky SK, Shaked NT
Cells 2022 Apr 13;11(8) doi: 10.3390/cells11081319. PMID: 35455999Free PMC Article
Tan C, Meng L, Lv M, He X, Sha Y, Tang D, Tan Y, Hu T, He W, Tu C, Nie H, Zhang H, Du J, Lu G, Fan LQ, Cao Y, Lin G, Tan YQ
Am J Hum Genet 2022 Jan 6;109(1):157-171. Epub 2021 Dec 20 doi: 10.1016/j.ajhg.2021.11.022. PMID: 34932939Free PMC Article
Morini D, Spaggiari G, Daolio J, Melli B, Nicoli A, De Feo G, Valli B, Viola D, Garganigo S, Magnani E, Pilia A, Polese A, Colla R, Simoni M, Aguzzoli L, Villani MT, Santi D
Andrology 2021 Jul;9(4):1176-1184. Epub 2021 May 6 doi: 10.1111/andr.13012. PMID: 33825345Free PMC Article
Liu C, Tu C, Wang L, Wu H, Houston BJ, Mastrorosa FK, Zhang W, Shen Y, Wang J, Tian S, Meng L, Cong J, Yang S, Jiang Y, Tang S, Zeng Y, Lv M, Lin G, Li J, Saiyin H, He X, Jin L, Touré A, Ray PF, Veltman JA, Shi Q, O'Bryan MK, Cao Y, Tan YQ, Zhang F
Am J Hum Genet 2021 Feb 4;108(2):309-323. Epub 2021 Jan 19 doi: 10.1016/j.ajhg.2021.01.002. PMID: 33472045Free PMC Article
Coutton C, Escoffier J, Martinez G, Arnoult C, Ray PF
Hum Reprod Update 2015 Jul-Aug;21(4):455-85. Epub 2015 Apr 17 doi: 10.1093/humupd/dmv020. PMID: 25888788

Clinical prediction guides

Kleshchev M, Osadchuk L, Osadchuk A
Front Biosci (Schol Ed) 2023 Sep 27;15(3):12. doi: 10.31083/j.fbs1503012. PMID: 37806952
Nassir M, Levi M, Dardikman-Yoffe G, Mirsky SK, Shaked NT
Cells 2022 Apr 13;11(8) doi: 10.3390/cells11081319. PMID: 35455999Free PMC Article
Tan C, Meng L, Lv M, He X, Sha Y, Tang D, Tan Y, Hu T, He W, Tu C, Nie H, Zhang H, Du J, Lu G, Fan LQ, Cao Y, Lin G, Tan YQ
Am J Hum Genet 2022 Jan 6;109(1):157-171. Epub 2021 Dec 20 doi: 10.1016/j.ajhg.2021.11.022. PMID: 34932939Free PMC Article
Morini D, Spaggiari G, Daolio J, Melli B, Nicoli A, De Feo G, Valli B, Viola D, Garganigo S, Magnani E, Pilia A, Polese A, Colla R, Simoni M, Aguzzoli L, Villani MT, Santi D
Andrology 2021 Jul;9(4):1176-1184. Epub 2021 May 6 doi: 10.1111/andr.13012. PMID: 33825345Free PMC Article
Liu C, Tu C, Wang L, Wu H, Houston BJ, Mastrorosa FK, Zhang W, Shen Y, Wang J, Tian S, Meng L, Cong J, Yang S, Jiang Y, Tang S, Zeng Y, Lv M, Lin G, Li J, Saiyin H, He X, Jin L, Touré A, Ray PF, Veltman JA, Shi Q, O'Bryan MK, Cao Y, Tan YQ, Zhang F
Am J Hum Genet 2021 Feb 4;108(2):309-323. Epub 2021 Jan 19 doi: 10.1016/j.ajhg.2021.01.002. PMID: 33472045Free PMC Article

Recent systematic reviews

Mazaheri Moghaddam M, Mazaheri Moghaddam M, Hamzeiy H, Baghbanzadeh A, Pashazadeh F, Sakhinia E
J Assist Reprod Genet 2021 Mar;38(3):573-586. Epub 2021 Jan 15 doi: 10.1007/s10815-020-02008-w. PMID: 33452591Free PMC Article
Girardet L, Augière C, Asselin MP, Belleannée C
Andrology 2019 Sep;7(5):588-602. Epub 2019 May 26 doi: 10.1111/andr.12650. PMID: 31131532
Lotti F, Maggi M
Hum Reprod Update 2015 Jan-Feb;21(1):56-83. Epub 2014 Jul 19 doi: 10.1093/humupd/dmu042. PMID: 25038770

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...