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Periventricular white matter hypodensities

MedGen UID:: 868326
•Concept ID:: C4022720
•: Finding

Synonym:	Periventricular cerebral white matter hypodensities

HPO:	HP:0012794

Definition

Multiple areas of darker than expected signal on magnetic resonance imaging emanating from the cerebral white matter that surrounds the cerebral ventricles. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVPeriventricular white matter hypodensities

Abnormal brain morphology
- Abnormal forebrain morphology
  - Abnormal cerebral morphology
    - Abnormal cerebral subcortex morphology
      - Abnormal cerebral white matter morphology
        Hypointensity of cerebral white matter on MRI
        Periventricular white matter hypodensities

Professional guidelines

PubMed

Evaluation of treatment of normal-pressure hydrocephalus.

Meyer JS, Kitagawa Y, Tanahashi N, Tachibana H, Kandula P, Cech DA, Clifton GL, Rose JE
J Neurosurg 1985 Apr;62(4):513-21. doi: 10.3171/jns.1985.62.4.0513. PMID: 3973721

Recent clinical studies

Diagnosis

Pure methotrexate encephalopathy presenting with seizures: CT and MRI features.

Lövblad K, Kelkar P, Ozdoba C, Ramelli G, Remonda L, Schroth G
Pediatr Radiol 1998 Feb;28(2):86-91. doi: 10.1007/s002470050299. PMID: 9472050

MRI appearance of AIDS subacute encephalopathy.

Shabas D, Gerard G, Cunha B, Rossi D
Comput Radiol 1987 Mar-Apr;11(2):69-73. doi: 10.1016/0730-4862(87)90013-8. PMID: 3608449

Therapy

Pure methotrexate encephalopathy presenting with seizures: CT and MRI features.

Lövblad K, Kelkar P, Ozdoba C, Ramelli G, Remonda L, Schroth G
Pediatr Radiol 1998 Feb;28(2):86-91. doi: 10.1007/s002470050299. PMID: 9472050

Clinical prediction guides

Pure methotrexate encephalopathy presenting with seizures: CT and MRI features.

Lövblad K, Kelkar P, Ozdoba C, Ramelli G, Remonda L, Schroth G
Pediatr Radiol 1998 Feb;28(2):86-91. doi: 10.1007/s002470050299. PMID: 9472050

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