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Functional abnormality of the gastrointestinal tract

MedGen UID:
868361
Concept ID:
C4022755
Pathologic Function
Synonyms: Functional abnormality of the GI tract; GI dysfunction
 
HPO: HP:0012719

Definition

Abnormal functionality of the gastrointestinal tract. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFunctional abnormality of the gastrointestinal tract

Professional guidelines

PubMed

Jach ME, Serefko A, Szopa A, Sajnaga E, Golczyk H, Santos LS, Borowicz-Reutt K, Sieniawska E
Molecules 2023 Apr 4;28(7) doi: 10.3390/molecules28073213. PMID: 37049975Free PMC Article
Miehlke S, Verhaegh B, Tontini GE, Madisch A, Langner C, Münch A
Lancet Gastroenterol Hepatol 2019 Apr;4(4):305-314. doi: 10.1016/S2468-1253(19)30048-2. PMID: 30860066
Camilleri M
Mayo Clin Proc 2018 Dec;93(12):1858-1872. doi: 10.1016/j.mayocp.2018.04.032. PMID: 30522596Free PMC Article

Recent clinical studies

Etiology

Mueller JL, Goldstein AM
Semin Pediatr Surg 2022 Apr;31(2):151157. Epub 2022 Apr 18 doi: 10.1016/j.sempedsurg.2022.151157. PMID: 35690468
Slater BJ, Pimpalwar A
Neoreviews 2020 Jun;21(6):e383-e391. doi: 10.1542/neo.21-6-e383. PMID: 32482700
Israelyan N, Del Colle A, Li Z, Park Y, Xing A, Jacobsen JPR, Luna RA, Jensen DD, Madra M, Saurman V, Rahim R, Latorre R, Law K, Carson W, Bunnett NW, Caron MG, Margolis KG
Gastroenterology 2019 Aug;157(2):507-521.e4. Epub 2019 May 7 doi: 10.1053/j.gastro.2019.04.022. PMID: 31071306Free PMC Article
Liddle RA
Brain Res 2018 Aug 15;1693(Pt B):201-206. Epub 2018 Jan 31 doi: 10.1016/j.brainres.2018.01.010. PMID: 29360467Free PMC Article
Holecek M
JPEN J Parenter Enteral Nutr 2013 Sep;37(5):607-16. Epub 2012 Sep 18 doi: 10.1177/0148607112460682. PMID: 22990615

Diagnosis

Rich BS, Bornstein E, Dolgin SE
Pediatr Rev 2022 May 1;43(5):266-274. doi: 10.1542/pir.2021-005177. PMID: 35490204
Ambartsumyan L, Smith C, Kapur RP
Pediatr Dev Pathol 2020 Jan-Feb;23(1):8-22. Epub 2019 Dec 2 doi: 10.1177/1093526619892351. PMID: 31791203
Butler Tjaden NE, Trainor PA
Transl Res 2013 Jul;162(1):1-15. Epub 2013 Mar 22 doi: 10.1016/j.trsl.2013.03.001. PMID: 23528997Free PMC Article
Solomon BD
Orphanet J Rare Dis 2011 Aug 16;6:56. doi: 10.1186/1750-1172-6-56. PMID: 21846383Free PMC Article
Cheng LK, O'Grady G, Du P, Egbuji JU, Windsor JA, Pullan AJ
Wiley Interdiscip Rev Syst Biol Med 2010 Jan-Feb;2(1):65-79. doi: 10.1002/wsbm.19. PMID: 20836011Free PMC Article

Therapy

Kang DW, Adams JB, Coleman DM, Pollard EL, Maldonado J, McDonough-Means S, Caporaso JG, Krajmalnik-Brown R
Sci Rep 2019 Apr 9;9(1):5821. doi: 10.1038/s41598-019-42183-0. PMID: 30967657Free PMC Article
Kang DW, Adams JB, Gregory AC, Borody T, Chittick L, Fasano A, Khoruts A, Geis E, Maldonado J, McDonough-Means S, Pollard EL, Roux S, Sadowsky MJ, Lipson KS, Sullivan MB, Caporaso JG, Krajmalnik-Brown R
Microbiome 2017 Jan 23;5(1):10. doi: 10.1186/s40168-016-0225-7. PMID: 28122648Free PMC Article
Suez J, Korem T, Zeevi D, Zilberman-Schapira G, Thaiss CA, Maza O, Israeli D, Zmora N, Gilad S, Weinberger A, Kuperman Y, Harmelin A, Kolodkin-Gal I, Shapiro H, Halpern Z, Segal E, Elinav E
Nature 2014 Oct 9;514(7521):181-6. Epub 2014 Sep 17 doi: 10.1038/nature13793. PMID: 25231862
Hsiao EY, McBride SW, Hsien S, Sharon G, Hyde ER, McCue T, Codelli JA, Chow J, Reisman SE, Petrosino JF, Patterson PH, Mazmanian SK
Cell 2013 Dec 19;155(7):1451-63. Epub 2013 Dec 5 doi: 10.1016/j.cell.2013.11.024. PMID: 24315484Free PMC Article
Holecek M
JPEN J Parenter Enteral Nutr 2013 Sep;37(5):607-16. Epub 2012 Sep 18 doi: 10.1177/0148607112460682. PMID: 22990615

Prognosis

Ludwig K, De Bartolo D, Salerno A, Ingravallo G, Cazzato G, Giacometti C, Dall'Igna P
Pathologica 2022 Feb;114(1):40-54. doi: 10.32074/1591-951X-553. PMID: 35212315Free PMC Article
Slater BJ, Pimpalwar A
Neoreviews 2020 Jun;21(6):e383-e391. doi: 10.1542/neo.21-6-e383. PMID: 32482700
Ambartsumyan L, Smith C, Kapur RP
Pediatr Dev Pathol 2020 Jan-Feb;23(1):8-22. Epub 2019 Dec 2 doi: 10.1177/1093526619892351. PMID: 31791203
Kang DW, Adams JB, Coleman DM, Pollard EL, Maldonado J, McDonough-Means S, Caporaso JG, Krajmalnik-Brown R
Sci Rep 2019 Apr 9;9(1):5821. doi: 10.1038/s41598-019-42183-0. PMID: 30967657Free PMC Article
Solomon BD
Orphanet J Rare Dis 2011 Aug 16;6:56. doi: 10.1186/1750-1172-6-56. PMID: 21846383Free PMC Article

Clinical prediction guides

Camilleri M, Sanders KM
Gastroenterology 2022 Jan;162(1):68-87.e1. Epub 2021 Oct 27 doi: 10.1053/j.gastro.2021.10.028. PMID: 34717924Free PMC Article
Sun J, Zhang J, Wang X, Ji F, Ronco C, Tian J, Yin Y
Crit Care 2020 Oct 19;24(1):614. doi: 10.1186/s13054-020-03327-1. PMID: 33076940Free PMC Article
Ambartsumyan L, Smith C, Kapur RP
Pediatr Dev Pathol 2020 Jan-Feb;23(1):8-22. Epub 2019 Dec 2 doi: 10.1177/1093526619892351. PMID: 31791203
Gosain A, Brinkman AS
Curr Opin Pediatr 2015 Jun;27(3):364-9. doi: 10.1097/MOP.0000000000000210. PMID: 25944307Free PMC Article
Levitt MA, Peña A
Orphanet J Rare Dis 2007 Jul 26;2:33. doi: 10.1186/1750-1172-2-33. PMID: 17651510Free PMC Article

Recent systematic reviews

Zdrhova L, Bitnar P, Balihar K, Kolar P, Madle K, Martinek M, Pandolfino JE, Martinek J
Dysphagia 2023 Apr;38(2):609-621. Epub 2022 Jul 16 doi: 10.1007/s00455-022-10494-6. PMID: 35842548Free PMC Article
Thwaites PA, Gibson PR, Burgell RE
J Gastroenterol Hepatol 2022 Sep;37(9):1693-1709. Epub 2022 Jul 20 doi: 10.1111/jgh.15927. PMID: 35750466Free PMC Article
Rajati F, Ahmadi N, Naghibzadeh ZA, Kazeminia M
J Transl Med 2022 Apr 11;20(1):175. doi: 10.1186/s12967-022-03380-0. PMID: 35410274Free PMC Article
Caputo C, Wood E, Jabbour L
Birth Defects Res C Embryo Today 2016 Jun;108(2):174-80. Epub 2016 Jun 13 doi: 10.1002/bdrc.21129. PMID: 27297122
Pandolfino JE, Gawron AJ
JAMA 2015 May 12;313(18):1841-52. doi: 10.1001/jama.2015.2996. PMID: 25965233

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