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Abnormal urine phosphate concentration

MedGen UID:
868434
•Concept ID:
C4022828
•
Finding
HPO: HP:0012599

Definition

An abnormal phosphate concentration in the urine. [from HPO]

Professional guidelines

PubMed

The Impact of Hypoparathyroidism Treatment on the Kidney in Children: Long-Term Retrospective Follow-Up Study.
Levy I, Licht C, Daneman A, Sochett E, Harrington J
J Clin Endocrinol Metab 2015 Nov;100(11):4106-13. Epub 2015 Aug 31 doi: 10.1210/jc.2015-2257. PMID: 26323021
Pathophysiology-based treatment of idiopathic calcium kidney stones.
Coe FL, Evan A, Worcester E
Clin J Am Soc Nephrol 2011 Aug;6(8):2083-92. doi: 10.2215/CJN.11321210. PMID: 21825103Free PMC Article
Biochemical and genetic studies in cystinuria: observations on double heterozygotes of genotype I-II.
Morin CL, Thompson MW, Jackson SH, Sass-Kortsak A
J Clin Invest 1971 Sep;50(9):1961-76. doi: 10.1172/JCI106688. PMID: 5564399Free PMC Article

Recent clinical studies

Etiology

Evidence for disordered acid-base handling in calcium stone-forming patients.
Worcester EM, Bergsland KJ, Gillen DL, Coe FL
Am J Physiol Renal Physiol 2020 Feb 1;318(2):F363-F374. Epub 2019 Dec 2 doi: 10.1152/ajprenal.00400.2019. PMID: 31790303Free PMC Article
Pesticide interactions and risks of sperm chromosomal abnormalities.
Figueroa ZI, Young HA, Mumford SL, Meeker JD, Barr DB, Gray GM, Perry MJ
Int J Hyg Environ Health 2019 Aug;222(7):1021-1029. Epub 2019 Jul 13 doi: 10.1016/j.ijheh.2019.07.001. PMID: 31311690Free PMC Article
Incomplete Distal Renal Tubular Acidosis and Kidney Stones.
Fuster DG, Moe OW
Adv Chronic Kidney Dis 2018 Jul;25(4):366-374. doi: 10.1053/j.ackd.2018.05.007. PMID: 30139463Free PMC Article
Diet-induced metabolic acidosis.
Adeva MM, Souto G
Clin Nutr 2011 Aug;30(4):416-21. Epub 2011 Apr 9 doi: 10.1016/j.clnu.2011.03.008. PMID: 21481501
Pseudo-(tumor-induced) rickets.
Whyte MP, Podgornik MN, Wollberg VA, Eddy MC, McAlister WH
J Bone Miner Res 2001 Aug;16(8):1564-71. doi: 10.1359/jbmr.2001.16.8.1564. PMID: 11499880

Diagnosis

Incomplete Distal Renal Tubular Acidosis and Kidney Stones.
Fuster DG, Moe OW
Adv Chronic Kidney Dis 2018 Jul;25(4):366-374. doi: 10.1053/j.ackd.2018.05.007. PMID: 30139463Free PMC Article
The future of phosphate binders: a perspective on novel therapeutics.
Cernaro V, Santoro D, Lucisano S, Nicocia G, Lacquaniti A, Buemi M
Expert Opin Investig Drugs 2014 Nov;23(11):1459-63. Epub 2014 Sep 22 doi: 10.1517/13543784.2014.962652. PMID: 25243756
Fahr's syndrome: literature review of current evidence.
Saleem S, Aslam HM, Anwar M, Anwar S, Saleem M, Saleem A, Rehmani MA
Orphanet J Rare Dis 2013 Oct 8;8:156. doi: 10.1186/1750-1172-8-156. PMID: 24098952Free PMC Article
Disorders of phosphate homeostasis and tissue mineralisation.
Bergwitz C, Jüppner H
Endocr Dev 2009;16:133-56. Epub 2009 Jun 3 doi: 10.1159/000223693. PMID: 19494665Free PMC Article
Adult hypophosphatasia.
Sorensen E, Flodgaard H
Acta Med Scand 1975 May;197(5):357-60. doi: 10.1111/j.0954-6820.1975.tb04934.x. PMID: 167553

Therapy

Incomplete Distal Renal Tubular Acidosis and Kidney Stones.
Fuster DG, Moe OW
Adv Chronic Kidney Dis 2018 Jul;25(4):366-374. doi: 10.1053/j.ackd.2018.05.007. PMID: 30139463Free PMC Article
The future of phosphate binders: a perspective on novel therapeutics.
Cernaro V, Santoro D, Lucisano S, Nicocia G, Lacquaniti A, Buemi M
Expert Opin Investig Drugs 2014 Nov;23(11):1459-63. Epub 2014 Sep 22 doi: 10.1517/13543784.2014.962652. PMID: 25243756
Diet-induced metabolic acidosis.
Adeva MM, Souto G
Clin Nutr 2011 Aug;30(4):416-21. Epub 2011 Apr 9 doi: 10.1016/j.clnu.2011.03.008. PMID: 21481501
Pseudo-(tumor-induced) rickets.
Whyte MP, Podgornik MN, Wollberg VA, Eddy MC, McAlister WH
J Bone Miner Res 2001 Aug;16(8):1564-71. doi: 10.1359/jbmr.2001.16.8.1564. PMID: 11499880
Adult hypophosphatasia.
Sorensen E, Flodgaard H
Acta Med Scand 1975 May;197(5):357-60. doi: 10.1111/j.0954-6820.1975.tb04934.x. PMID: 167553

Prognosis

Pharmacogenetic determinants of kidney-associated urinary and serum abnormalities in antiretroviral-treated HIV-positive patients.
Cusato J, Calcagno A, Marinaro L, Avataneo V, DʹAvolio A, Di Perri G, Bonora S
Pharmacogenomics J 2020 Apr;20(2):202-212. Epub 2019 Oct 16 doi: 10.1038/s41397-019-0109-x. PMID: 31619748
Pathophysiology-based treatment of idiopathic calcium kidney stones.
Coe FL, Evan A, Worcester E
Clin J Am Soc Nephrol 2011 Aug;6(8):2083-92. doi: 10.2215/CJN.11321210. PMID: 21825103Free PMC Article
Diet-induced metabolic acidosis.
Adeva MM, Souto G
Clin Nutr 2011 Aug;30(4):416-21. Epub 2011 Apr 9 doi: 10.1016/j.clnu.2011.03.008. PMID: 21481501
Pseudo-(tumor-induced) rickets.
Whyte MP, Podgornik MN, Wollberg VA, Eddy MC, McAlister WH
J Bone Miner Res 2001 Aug;16(8):1564-71. doi: 10.1359/jbmr.2001.16.8.1564. PMID: 11499880
The electrolytes in hyponatremia.
Graber M, Corish D
Am J Kidney Dis 1991 Nov;18(5):527-45. doi: 10.1016/s0272-6386(12)80647-0. PMID: 1835285

Clinical prediction guides

Phthalate exposure and childhood overweight and obesity: Urinary metabolomic evidence.
Xia B, Zhu Q, Zhao Y, Ge W, Zhao Y, Song Q, Zhou Y, Shi H, Zhang Y
Environ Int 2018 Dec;121(Pt 1):159-168. Epub 2018 Sep 9 doi: 10.1016/j.envint.2018.09.001. PMID: 30208345
Pathophysiology-based treatment of idiopathic calcium kidney stones.
Coe FL, Evan A, Worcester E
Clin J Am Soc Nephrol 2011 Aug;6(8):2083-92. doi: 10.2215/CJN.11321210. PMID: 21825103Free PMC Article
Clinical and metabolic evaluation of Korean patients with urolithiasis.
Park KJ, Jeon SS, Han DH, Lee SY
Scand J Clin Lab Invest 2011 Oct;71(6):481-5. Epub 2011 Jun 30 doi: 10.3109/00365513.2011.587528. PMID: 21714706
Diet-induced metabolic acidosis.
Adeva MM, Souto G
Clin Nutr 2011 Aug;30(4):416-21. Epub 2011 Apr 9 doi: 10.1016/j.clnu.2011.03.008. PMID: 21481501
Clinical chemistry of vitamin B6.
Wilson RG, Davis RE
Adv Clin Chem 1983;23:1-68. doi: 10.1016/s0065-2423(08)60397-2. PMID: 6398613

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