U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormality of the internal capsule

MedGen UID:
868481
Concept ID:
C4022875
Anatomical Abnormality
HPO: HP:0012502

Definition

An anomaly of the internal capsule, which is an area of white matter in the brain that separates the caudate nucleus and the thalamus from the putamen and the globus pallidus. [from HPO]

Professional guidelines

PubMed

Verma S, Agrawal D, Singh M
Neurol India 2023 Mar-Apr;71(Supplement):S49-S58. doi: 10.4103/0028-3886.373644. PMID: 37026334
Nathal E, Serrano-Rubio A, Monroy-Sosa A, Gutiérrez-Ávila O, Vázquez-Gregorio R, Degollado-García J, Lee Á
Neurosurg Focus 2022 Jul;53(1):E10. doi: 10.3171/2022.4.FOCUS22109. PMID: 35901718
Awadalla M, Mahmoud M, McNamara P, Wassef W
Curr Opin Gastroenterol 2020 Nov;36(6):538-546. doi: 10.1097/MOG.0000000000000675. PMID: 32925176

Recent clinical studies

Etiology

Verma S, Agrawal D, Singh M
Neurol India 2023 Mar-Apr;71(Supplement):S49-S58. doi: 10.4103/0028-3886.373644. PMID: 37026334
Bencurova P, Laakso H, Salo RA, Paasonen E, Manninen E, Paasonen J, Michaeli S, Mangia S, Bares M, Brazdil M, Kubova H, Gröhn O
Neurobiol Dis 2022 Jan;162:105566. Epub 2021 Nov 24 doi: 10.1016/j.nbd.2021.105566. PMID: 34838665Free PMC Article
Usai-Satta P, Bellini M, Morelli O, Geri F, Lai M, Bassotti G
World J Gastroenterol 2020 May 21;26(19):2333-2348. doi: 10.3748/wjg.v26.i19.2333. PMID: 32476797Free PMC Article
Haghighi-Morad M, Naseri Z, Jamshidi N, Hassanian-Moghaddam H, Zamani N, Ahmad-Molaei L
BMC Med Imaging 2020 Jan 17;20(1):6. doi: 10.1186/s12880-020-0410-9. PMID: 31952488Free PMC Article
Caplan LR, Schmahmann JD, Kase CS, Feldmann E, Baquis G, Greenberg JP, Gorelick PB, Helgason C, Hier DB
Arch Neurol 1990 Feb;47(2):133-43. doi: 10.1001/archneur.1990.00530020029011. PMID: 2405818

Diagnosis

Coradine TLC, Guida LOC, Fraiman P, Santos AJ, Pedroso JL, Barsottini OGP
Pract Neurol 2023 Oct;23(5):408-410. Epub 2023 May 5 doi: 10.1136/pn-2023-003696. PMID: 37147122
Alsunaydih FN, Yuce MR
Physiol Meas 2021 May 11;42(4) doi: 10.1088/1361-6579/abedc0. PMID: 33706294
Awadalla M, Mahmoud M, McNamara P, Wassef W
Curr Opin Gastroenterol 2020 Nov;36(6):538-546. doi: 10.1097/MOG.0000000000000675. PMID: 32925176
Usai-Satta P, Bellini M, Morelli O, Geri F, Lai M, Bassotti G
World J Gastroenterol 2020 May 21;26(19):2333-2348. doi: 10.3748/wjg.v26.i19.2333. PMID: 32476797Free PMC Article
Badji A, Sabra D, Bherer L, Cohen-Adad J, Girouard H, Gauthier CJ
Ageing Res Rev 2019 Aug;53:100907. Epub 2019 May 4 doi: 10.1016/j.arr.2019.05.001. PMID: 31063866

Therapy

Nwonu CNS
West Afr J Med 2022 Oct 20;39(10):1075-1983. PMID: 36260866
Moretti R, Caruso P
Int J Mol Sci 2020 Sep 5;21(18) doi: 10.3390/ijms21186506. PMID: 32899565Free PMC Article
Vedachalam S, Balasubramanian G, Haas GJ, Krishna SG
World J Gastroenterol 2020 May 28;26(20):2550-2558. doi: 10.3748/wjg.v26.i20.2550. PMID: 32523310Free PMC Article
Usai-Satta P, Bellini M, Morelli O, Geri F, Lai M, Bassotti G
World J Gastroenterol 2020 May 21;26(19):2333-2348. doi: 10.3748/wjg.v26.i19.2333. PMID: 32476797Free PMC Article
Hernández Salazar M, Zarate Méndez A, Meneses Luna O, Ledesma Torres L, Paniagua Sierra R, Sánchez Moreno MC, Serrato Avila JL
Neurocirugia (Astur : Engl Ed) 2018 Nov-Dec;29(6):296-303. Epub 2018 Jun 18 doi: 10.1016/j.neucir.2018.05.003. PMID: 29914842

Prognosis

Sharma Y, Saini AG, Kaur R, Bhatia V, Didwal G, Kumar P, Uppala R
Neuropediatrics 2022 Jun;53(3):167-175. Epub 2022 Jan 28 doi: 10.1055/s-0042-1742322. PMID: 35098521
Shuyao W, Mingyang B, Feifei M, Xiaoqin H
J Gastrointest Surg 2022 Feb;26(2):341-351. Epub 2021 Sep 10 doi: 10.1007/s11605-021-05107-w. PMID: 34506016
Seo YM, Im SA, Sung IK, Youn YA
Medicine (Baltimore) 2020 Nov 25;99(48):e23176. doi: 10.1097/MD.0000000000023176. PMID: 33235078Free PMC Article
Cowan FM, de Vries LS
Semin Fetal Neonatal Med 2005 Oct;10(5):461-74. doi: 10.1016/j.siny.2005.05.007. PMID: 16002354
Chung CS, Caplan LR, Han W, Pessin MS, Lee KH, Kim JM
Brain 1996 Dec;119 ( Pt 6):1873-86. doi: 10.1093/brain/119.6.1873. PMID: 9009994

Clinical prediction guides

Bencurova P, Laakso H, Salo RA, Paasonen E, Manninen E, Paasonen J, Michaeli S, Mangia S, Bares M, Brazdil M, Kubova H, Gröhn O
Neurobiol Dis 2022 Jan;162:105566. Epub 2021 Nov 24 doi: 10.1016/j.nbd.2021.105566. PMID: 34838665Free PMC Article
Alsunaydih FN, Yuce MR
Physiol Meas 2021 May 11;42(4) doi: 10.1088/1361-6579/abedc0. PMID: 33706294
Haghighi-Morad M, Naseri Z, Jamshidi N, Hassanian-Moghaddam H, Zamani N, Ahmad-Molaei L
BMC Med Imaging 2020 Jan 17;20(1):6. doi: 10.1186/s12880-020-0410-9. PMID: 31952488Free PMC Article
Hosoe N, Takabayashi K, Ogata H, Kanai T
Dig Endosc 2019 Sep;31(5):498-507. Epub 2019 Feb 10 doi: 10.1111/den.13346. PMID: 30656743
Romaniello R, Arrigoni F, Fry AE, Bassi MT, Rees MI, Borgatti R, Pilz DT, Cushion TD
Eur J Med Genet 2018 Dec;61(12):744-754. Epub 2018 Jul 17 doi: 10.1016/j.ejmg.2018.07.012. PMID: 30016746

Recent systematic reviews

Crotti M, Genoe S, Ben Itzhak N, Mailleux L, Ortibus E
Brain Dev 2024 Feb;46(2):75-92. Epub 2023 Nov 27 doi: 10.1016/j.braindev.2023.11.002. PMID: 38016876
Lindsey HM, Hodges CB, Greer KM, Wilde EA, Merkley TL
Neuropsychol Rev 2023 Mar;33(1):42-121. Epub 2021 Mar 15 doi: 10.1007/s11065-021-09485-5. PMID: 33721207
Luttenbacher I, Phillips A, Kazemi R, Hadipour AL, Sanghvi I, Martinez J, Adamson MM
J Psychiatr Res 2022 Mar;147:324-348. Epub 2021 Dec 28 doi: 10.1016/j.jpsychires.2021.12.042. PMID: 35151030
Connaughton M, Whelan R, O'Hanlon E, McGrath J
Neuroimage Clin 2022;33:102957. Epub 2022 Feb 7 doi: 10.1016/j.nicl.2022.102957. PMID: 35149304Free PMC Article
Piras F, Piras F, Chiapponi C, Girardi P, Caltagirone C, Spalletta G
Cortex 2015 Jan;62:89-108. Epub 2013 Feb 26 doi: 10.1016/j.cortex.2013.01.016. PMID: 23582297

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...