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Abnormality of the internal capsule

MedGen UID:
868481
•Concept ID:
C4022875
•
Anatomical Abnormality
HPO: HP:0012502

Definition

An anomaly of the internal capsule, which is an area of white matter in the brain that separates the caudate nucleus and the thalamus from the putamen and the globus pallidus. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormality of the internal capsule

Professional guidelines

PubMed

Role of Gamma Knife Radiosurgery in the Management of Functional Disorders - A Literature Review.
Verma S, Agrawal D, Singh M
Neurol India 2023 Mar-Apr;71(Supplement):S49-S58. doi: 10.4103/0028-3886.373644. PMID: 37026334
Gastric vascular abnormalities: diagnosis and management.
Awadalla M, Mahmoud M, McNamara P, Wassef W
Curr Opin Gastroenterol 2020 Nov;36(6):538-546. doi: 10.1097/MOG.0000000000000675. PMID: 32925176
Embolization of the choroidal artery in the treatment of cerebral arteriovenous malformations.
Elkordy A, Endo H, Sato K, Matsumoto Y, Kondo R, Niizuma K, Endo T, Fujimura M, Tominaga T
J Neurosurg 2017 Apr;126(4):1114-1122. Epub 2016 May 6 doi: 10.3171/2016.2.JNS152370. PMID: 27153173

Recent clinical studies

Etiology

Role of Gamma Knife Radiosurgery in the Management of Functional Disorders - A Literature Review.
Verma S, Agrawal D, Singh M
Neurol India 2023 Mar-Apr;71(Supplement):S49-S58. doi: 10.4103/0028-3886.373644. PMID: 37026334
Infantile status epilepticus disrupts myelin development.
Bencurova P, Laakso H, Salo RA, Paasonen E, Manninen E, Paasonen J, Michaeli S, Mangia S, Bares M, Brazdil M, Kubova H, Gröhn O
Neurobiol Dis 2022 Jan;162:105566. Epub 2021 Nov 24 doi: 10.1016/j.nbd.2021.105566. PMID: 34838665Free PMC Article
Gastroparesis: New insights into an old disease.
Usai-Satta P, Bellini M, Morelli O, Geri F, Lai M, Bassotti G
World J Gastroenterol 2020 May 21;26(19):2333-2348. doi: 10.3748/wjg.v26.i19.2333. PMID: 32476797Free PMC Article
Methadone-induced encephalopathy: a case series and literature review.
Haghighi-Morad M, Naseri Z, Jamshidi N, Hassanian-Moghaddam H, Zamani N, Ahmad-Molaei L
BMC Med Imaging 2020 Jan 17;20(1):6. doi: 10.1186/s12880-020-0410-9. PMID: 31952488Free PMC Article
Caudate infarcts.
Caplan LR, Schmahmann JD, Kase CS, Feldmann E, Baquis G, Greenberg JP, Gorelick PB, Helgason C, Hier DB
Arch Neurol 1990 Feb;47(2):133-43. doi: 10.1001/archneur.1990.00530020029011. PMID: 2405818

Diagnosis

White matter microstructure in children and adolescents with ADHD.
Connaughton M, Whelan R, O'Hanlon E, McGrath J
Neuroimage Clin 2022;33:102957. Epub 2022 Feb 7 doi: 10.1016/j.nicl.2022.102957. PMID: 35149304Free PMC Article
Next-generation ingestible devices: sensing, locomotion and navigation.
Alsunaydih FN, Yuce MR
Physiol Meas 2021 May 11;42(4) doi: 10.1088/1361-6579/abedc0. PMID: 33706294
Gastric vascular abnormalities: diagnosis and management.
Awadalla M, Mahmoud M, McNamara P, Wassef W
Curr Opin Gastroenterol 2020 Nov;36(6):538-546. doi: 10.1097/MOG.0000000000000675. PMID: 32925176
Gastroparesis: New insights into an old disease.
Usai-Satta P, Bellini M, Morelli O, Geri F, Lai M, Bassotti G
World J Gastroenterol 2020 May 21;26(19):2333-2348. doi: 10.3748/wjg.v26.i19.2333. PMID: 32476797Free PMC Article
Arterial stiffness and brain integrity: A review of MRI findings.
Badji A, Sabra D, Bherer L, Cohen-Adad J, Girouard H, Gauthier CJ
Ageing Res Rev 2019 Aug;53:100907. Epub 2019 May 4 doi: 10.1016/j.arr.2019.05.001. PMID: 31063866

Therapy

Neuronal Cell Mechanisms of Pain.
Nwonu CNS
West Afr J Med 2022 Oct 20;39(10):1075-1983. PMID: 36260866
An Iatrogenic Model of Brain Small-Vessel Disease: Post-Radiation Encephalopathy.
Moretti R, Caruso P
Int J Mol Sci 2020 Sep 5;21(18) doi: 10.3390/ijms21186506. PMID: 32899565Free PMC Article
Treatment of gastrointestinal bleeding in left ventricular assist devices: A comprehensive review.
Vedachalam S, Balasubramanian G, Haas GJ, Krishna SG
World J Gastroenterol 2020 May 28;26(20):2550-2558. doi: 10.3748/wjg.v26.i20.2550. PMID: 32523310Free PMC Article
Gastroparesis: New insights into an old disease.
Usai-Satta P, Bellini M, Morelli O, Geri F, Lai M, Bassotti G
World J Gastroenterol 2020 May 21;26(19):2333-2348. doi: 10.3748/wjg.v26.i19.2333. PMID: 32476797Free PMC Article
The role of diffusion tensor imaging and fractional anisotropy in the evaluation of patients with idiopathic normal pressure hydrocephalus: a literature review.
Siasios I, Kapsalaki EZ, Fountas KN, Fotiadou A, Dorsch A, Vakharia K, Pollina J, Dimopoulos V
Neurosurg Focus 2016 Sep;41(3):E12. doi: 10.3171/2016.6.FOCUS16192. PMID: 27581308

Prognosis

Neurodegeneration and Early Infantile Epilepsy Associated with ITPA Variants: A Case Series and Review of Literature.
Sharma Y, Saini AG, Kaur R, Bhatia V, Didwal G, Kumar P, Uppala R
Neuropediatrics 2022 Jun;53(3):167-175. Epub 2022 Jan 28 doi: 10.1055/s-0042-1742322. PMID: 35098521
CK19 Predicts Recurrence and Prognosis of HBV Positive HCC.
Shuyao W, Mingyang B, Feifei M, Xiaoqin H
J Gastrointest Surg 2022 Feb;26(2):341-351. Epub 2021 Sep 10 doi: 10.1007/s11605-021-05107-w. PMID: 34506016
A validated clinical MRI injury scoring system in neonatal hypoxic-ischemic encephalopathy.
Trivedi SB, Vesoulis ZA, Rao R, Liao SM, Shimony JS, McKinstry RC, Mathur AM
Pediatr Radiol 2017 Oct;47(11):1491-1499. Epub 2017 Jun 16 doi: 10.1007/s00247-017-3893-y. PMID: 28623417Free PMC Article
The internal capsule in neonatal imaging.
Cowan FM, de Vries LS
Semin Fetal Neonatal Med 2005 Oct;10(5):461-74. doi: 10.1016/j.siny.2005.05.007. PMID: 16002354
Thalamic haemorrhage.
Chung CS, Caplan LR, Han W, Pessin MS, Lee KH, Kim JM
Brain 1996 Dec;119 ( Pt 6):1873-86. doi: 10.1093/brain/119.6.1873. PMID: 9009994

Clinical prediction guides

Next-generation ingestible devices: sensing, locomotion and navigation.
Alsunaydih FN, Yuce MR
Physiol Meas 2021 May 11;42(4) doi: 10.1088/1361-6579/abedc0. PMID: 33706294
Methadone-induced encephalopathy: a case series and literature review.
Haghighi-Morad M, Naseri Z, Jamshidi N, Hassanian-Moghaddam H, Zamani N, Ahmad-Molaei L
BMC Med Imaging 2020 Jan 17;20(1):6. doi: 10.1186/s12880-020-0410-9. PMID: 31952488Free PMC Article
Capsule endoscopy for small-intestinal disorders: Current status.
Hosoe N, Takabayashi K, Ogata H, Kanai T
Dig Endosc 2019 Sep;31(5):498-507. Epub 2019 Feb 10 doi: 10.1111/den.13346. PMID: 30656743
Tubulin genes and malformations of cortical development.
Romaniello R, Arrigoni F, Fry AE, Bassi MT, Rees MI, Borgatti R, Pilz DT, Cushion TD
Eur J Med Genet 2018 Dec;61(12):744-754. Epub 2018 Jul 17 doi: 10.1016/j.ejmg.2018.07.012. PMID: 30016746
A validated clinical MRI injury scoring system in neonatal hypoxic-ischemic encephalopathy.
Trivedi SB, Vesoulis ZA, Rao R, Liao SM, Shimony JS, McKinstry RC, Mathur AM
Pediatr Radiol 2017 Oct;47(11):1491-1499. Epub 2017 Jun 16 doi: 10.1007/s00247-017-3893-y. PMID: 28623417Free PMC Article

Recent systematic reviews

Diffusion-Weighted Imaging in Mild Traumatic Brain Injury: A Systematic Review of the Literature.
Lindsey HM, Hodges CB, Greer KM, Wilde EA, Merkley TL
Neuropsychol Rev 2023 Mar;33(1):42-121. Epub 2021 Mar 15 doi: 10.1007/s11065-021-09485-5. PMID: 33721207
Transdiagnostic role of glutamate and white matter damage in neuropsychiatric disorders: A Systematic Review.
Luttenbacher I, Phillips A, Kazemi R, Hadipour AL, Sanghvi I, Martinez J, Adamson MM
J Psychiatr Res 2022 Mar;147:324-348. Epub 2021 Dec 28 doi: 10.1016/j.jpsychires.2021.12.042. PMID: 35151030
White matter microstructure in children and adolescents with ADHD.
Connaughton M, Whelan R, O'Hanlon E, McGrath J
Neuroimage Clin 2022;33:102957. Epub 2022 Feb 7 doi: 10.1016/j.nicl.2022.102957. PMID: 35149304Free PMC Article
White-matter free-water diffusion MRI in schizophrenia: a systematic review and meta-analysis.
Carreira Figueiredo I, Borgan F, Pasternak O, Turkheimer FE, Howes OD
Neuropsychopharmacology 2022 Jun;47(7):1413-1420. Epub 2022 Jan 15 doi: 10.1038/s41386-022-01272-x. PMID: 35034098Free PMC Article
Widespread structural brain changes in OCD: a systematic review of voxel-based morphometry studies.
Piras F, Piras F, Chiapponi C, Girardi P, Caltagirone C, Spalletta G
Cortex 2015 Jan;62:89-108. Epub 2013 Feb 26 doi: 10.1016/j.cortex.2013.01.016. PMID: 23582297

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