U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal circulating enzyme concentration or activity

MedGen UID:
868523
Concept ID:
C4022922
Finding
Synonym: Abnormal enzyme/coenzyme activity
 
HPO: HP:0012379

Definition

An altered ability of any enzyme or their cofactors to act as catalysts. This term includes changes due to altered levels of an enzyme. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal circulating enzyme concentration or activity

Conditions with this feature

Deoxyribose-5-phosphate aldolase deficiency
MedGen UID:
377617
Concept ID:
C1852200
Disease or Syndrome

Professional guidelines

PubMed

Menopause 2021 Sep 1;28(9):973-997. doi: 10.1097/GME.0000000000001831. PMID: 34448749
Izquierdo M, Merchant RA, Morley JE, Anker SD, Aprahamian I, Arai H, Aubertin-Leheudre M, Bernabei R, Cadore EL, Cesari M, Chen LK, de Souto Barreto P, Duque G, Ferrucci L, Fielding RA, García-Hermoso A, Gutiérrez-Robledo LM, Harridge SDR, Kirk B, Kritchevsky S, Landi F, Lazarus N, Martin FC, Marzetti E, Pahor M, Ramírez-Vélez R, Rodriguez-Mañas L, Rolland Y, Ruiz JG, Theou O, Villareal DT, Waters DL, Won Won C, Woo J, Vellas B, Fiatarone Singh M
J Nutr Health Aging 2021;25(7):824-853. doi: 10.1007/s12603-021-1665-8. PMID: 34409961
Styne DM, Arslanian SA, Connor EL, Farooqi IS, Murad MH, Silverstein JH, Yanovski JA
J Clin Endocrinol Metab 2017 Mar 1;102(3):709-757. doi: 10.1210/jc.2016-2573. PMID: 28359099Free PMC Article

Recent clinical studies

Etiology

Billinger SA, Arena R, Bernhardt J, Eng JJ, Franklin BA, Johnson CM, MacKay-Lyons M, Macko RF, Mead GE, Roth EJ, Shaughnessy M, Tang A; American Heart Association Stroke Council; Council on Cardiovascular and Stroke Nursing; Council on Lifestyle and Cardiometabolic Health; Council on Epidemiology and Prevention; Council on Clinical Cardiology
Stroke 2014 Aug;45(8):2532-53. Epub 2014 May 20 doi: 10.1161/STR.0000000000000022. PMID: 24846875
González-Gross M, Meléndez A
Nutr Hosp 2013 Sep;28 Suppl 5:89-98. doi: 10.3305/nh.2013.28.sup5.6923. PMID: 24010748
Sun F, Norman IJ, While AE
BMC Public Health 2013 May 6;13:449. doi: 10.1186/1471-2458-13-449. PMID: 23648225Free PMC Article
Landry BW, Driscoll SW
PM R 2012 Nov;4(11):826-32. doi: 10.1016/j.pmrj.2012.09.585. PMID: 23174545
Tudor-Locke C, Bassett DR Jr
Sports Med 2004;34(1):1-8. doi: 10.2165/00007256-200434010-00001. PMID: 14715035

Diagnosis

Tache Y, Larauche M, Yuan PQ, Million M
Curr Mol Pharmacol 2018;11(1):51-71. doi: 10.2174/1874467210666170224095741. PMID: 28240194Free PMC Article
Scott J, Murray G, Henry C, Morken G, Scott E, Angst J, Merikangas KR, Hickie IB
JAMA Psychiatry 2017 Feb 1;74(2):189-196. doi: 10.1001/jamapsychiatry.2016.3459. PMID: 28002572
Helgadóttir B, Forsell Y, Ekblom Ö
PLoS One 2015;10(1):e0115894. Epub 2015 Jan 13 doi: 10.1371/journal.pone.0115894. PMID: 25585123Free PMC Article
Kwok CS, Anderson SG, Myint PK, Mamas MA, Loke YK
Int J Cardiol 2014 Dec 15;177(2):467-76. Epub 2014 Sep 28 doi: 10.1016/j.ijcard.2014.09.104. PMID: 25443248
Bennell K, Dobson F, Hinman R
Arthritis Care Res (Hoboken) 2011 Nov;63 Suppl 11:S350-70. doi: 10.1002/acr.20538. PMID: 22588756

Therapy

Poyatos-León R, García-Hermoso A, Sanabria-Martínez G, Álvarez-Bueno C, Cavero-Redondo I, Martínez-Vizcaíno V
Birth 2017 Sep;44(3):200-208. Epub 2017 Jun 6 doi: 10.1111/birt.12294. PMID: 28589648
French B, Thomas LH, Coupe J, McMahon NE, Connell L, Harrison J, Sutton CJ, Tishkovskaya S, Watkins CL
Cochrane Database Syst Rev 2016 Nov 14;11(11):CD006073. doi: 10.1002/14651858.CD006073.pub3. PMID: 27841442Free PMC Article
Castro I, Waclawovsky G, Marcadenti A
Curr Hypertens Rev 2015;11(2):91-9. doi: 10.2174/1573402111666150429170302. PMID: 25921545
Dobbins M, Husson H, DeCorby K, LaRocca RL
Cochrane Database Syst Rev 2013 Feb 28;2013(2):CD007651. doi: 10.1002/14651858.CD007651.pub2. PMID: 23450577Free PMC Article
Ada L, Dorsch S, Canning CG
Aust J Physiother 2006;52(4):241-8. doi: 10.1016/s0004-9514(06)70003-4. PMID: 17132118

Prognosis

Lee DH, Rezende LFM, Joh HK, Keum N, Ferrari G, Rey-Lopez JP, Rimm EB, Tabung FK, Giovannucci EL
Circulation 2022 Aug 16;146(7):523-534. Epub 2022 Jul 25 doi: 10.1161/CIRCULATIONAHA.121.058162. PMID: 35876019Free PMC Article
Chudasama YV, Khunti KK, Zaccardi F, Rowlands AV, Yates T, Gillies CL, Davies MJ, Dhalwani NN
BMC Med 2019 Jun 12;17(1):108. doi: 10.1186/s12916-019-1339-0. PMID: 31186007Free PMC Article
McTiernan A, Friedenreich CM, Katzmarzyk PT, Powell KE, Macko R, Buchner D, Pescatello LS, Bloodgood B, Tennant B, Vaux-Bjerke A, George SM, Troiano RP, Piercy KL; 2018 PHYSICAL ACTIVITY GUIDELINES ADVISORY COMMITTEE*
Med Sci Sports Exerc 2019 Jun;51(6):1252-1261. doi: 10.1249/MSS.0000000000001937. PMID: 31095082Free PMC Article
Tipping CJ, Harrold M, Holland A, Romero L, Nisbet T, Hodgson CL
Intensive Care Med 2017 Feb;43(2):171-183. Epub 2016 Nov 18 doi: 10.1007/s00134-016-4612-0. PMID: 27864615
Biswas A, Oh PI, Faulkner GE, Bajaj RR, Silver MA, Mitchell MS, Alter DA
Ann Intern Med 2015 Jan 20;162(2):123-32. doi: 10.7326/M14-1651. PMID: 25599350

Clinical prediction guides

Pires CDS, Marba STM, Caldas JPS, Stopiglia MCS
Rev Paul Pediatr 2020;38:e2018286. Epub 2020 May 8 doi: 10.1590/1984-0462/2020/38/2018286. PMID: 32401947Free PMC Article
Drew PJ, Winder AT, Zhang Q
Neuroscientist 2019 Aug;25(4):298-313. Epub 2018 Oct 12 doi: 10.1177/1073858418805427. PMID: 30311838Free PMC Article
Fulk GD, He Y, Boyne P, Dunning K
Stroke 2017 Feb;48(2):406-411. Epub 2017 Jan 5 doi: 10.1161/STROKEAHA.116.015309. PMID: 28057807
Stolte E, Hopman-Rock M, Aartsen MJ, van Tilburg TG, Chorus A
J Aging Phys Act 2017 Jul;25(3):438-445. Epub 2017 Jun 12 doi: 10.1123/japa.2016-0182. PMID: 27992247
Einspieler C, Peharz R, Marschik PB
J Pediatr (Rio J) 2016 May-Jun;92(3 Suppl 1):S64-70. Epub 2016 Mar 17 doi: 10.1016/j.jped.2015.12.003. PMID: 26997356

Recent systematic reviews

Sardi L, Idri A, Fernández-Alemán JL
J Biomed Inform 2017 Jul;71:31-48. Epub 2017 May 20 doi: 10.1016/j.jbi.2017.05.011. PMID: 28536062
Tipping CJ, Harrold M, Holland A, Romero L, Nisbet T, Hodgson CL
Intensive Care Med 2017 Feb;43(2):171-183. Epub 2016 Nov 18 doi: 10.1007/s00134-016-4612-0. PMID: 27864615
de Labra C, Guimaraes-Pinheiro C, Maseda A, Lorenzo T, Millán-Calenti JC
BMC Geriatr 2015 Dec 2;15:154. doi: 10.1186/s12877-015-0155-4. PMID: 26626157Free PMC Article
Aune D, Norat T, Leitzmann M, Tonstad S, Vatten LJ
Eur J Epidemiol 2015 Jul;30(7):529-42. Epub 2015 Jun 20 doi: 10.1007/s10654-015-0056-z. PMID: 26092138
Teixeira PJ, Carraça EV, Markland D, Silva MN, Ryan RM
Int J Behav Nutr Phys Act 2012 Jun 22;9:78. doi: 10.1186/1479-5868-9-78. PMID: 22726453Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...