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Abnormality of bone marrow stromal cells

MedGen UID:
868634
•Concept ID:
C4023034
•
Anatomical Abnormality
HPO: HP:0012129

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormality of bone marrow stromal cells

Professional guidelines

PubMed

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Recent clinical studies

Therapy

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Ruxolitinib improves hematopoietic regeneration by restoring mesenchymal stromal cell function in acute graft-versus-host disease.
Lin Y, Gu Q, Lu S, Pan Z, Yang Z, Li Y, Yang S, Lv Y, Zheng Z, Sun G, Gou F, Xu C, Zhao X, Wang F, Wang C, Yuan S, Xie X, Cao Y, Liu Y, Gu W, Cheng T, Cheng H, Hu X
J Clin Invest 2023 Aug 1;133(15) doi: 10.1172/JCI162201. PMID: 37338986Free PMC Article
Non-operative management of shoulder osteoarthritis: Current concepts.
Yamamoto N, Szymski D, Voss A, Ishikawa H, Muraki T, Cunha RA, Ejnisman B, Noack J, McCarty E, Mulcahey MK, Itoi E
J ISAKOS 2023 Oct;8(5):289-295. Epub 2023 Jun 13 doi: 10.1016/j.jisako.2023.06.002. PMID: 37321293
Efficacy and Safety of Umbilical Cord Mesenchymal Stem Cell Therapy for Rheumatoid Arthritis Patients: A Prospective Phase I/II Study.
Wang L, Huang S, Li S, Li M, Shi J, Bai W, Wang Q, Zheng L, Liu Y
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Prognosis

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T cell abnormalities in systemic sclerosis.
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Abnormally elevated USP37 expression in breast cancer stem cells regulates stemness, epithelial-mesenchymal transition and cisplatin sensitivity.
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J Exp Clin Cancer Res 2018 Nov 27;37(1):287. doi: 10.1186/s13046-018-0934-9. PMID: 30482232Free PMC Article

Clinical prediction guides

Ruxolitinib improves hematopoietic regeneration by restoring mesenchymal stromal cell function in acute graft-versus-host disease.
Lin Y, Gu Q, Lu S, Pan Z, Yang Z, Li Y, Yang S, Lv Y, Zheng Z, Sun G, Gou F, Xu C, Zhao X, Wang F, Wang C, Yuan S, Xie X, Cao Y, Liu Y, Gu W, Cheng T, Cheng H, Hu X
J Clin Invest 2023 Aug 1;133(15) doi: 10.1172/JCI162201. PMID: 37338986Free PMC Article
Decorin promotes decidual M1-like macrophage polarization via mitochondrial dysfunction resulting in recurrent pregnancy loss.
Wang L, Wang H, Luo J, Xie T, Mor G, Liao A
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IL-7: Comprehensive review.
Winer H, Rodrigues GOL, Hixon JA, Aiello FB, Hsu TC, Wachter BT, Li W, Durum SK
Cytokine 2022 Dec;160:156049. Epub 2022 Oct 3 doi: 10.1016/j.cyto.2022.156049. PMID: 36201890
Disease modeling of pulmonary fibrosis using human pluripotent stem cell-derived alveolar organoids.
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Stemming retinal regeneration with pluripotent stem cells.
Jin ZB, Gao ML, Deng WL, Wu KC, Sugita S, Mandai M, Takahashi M
Prog Retin Eye Res 2019 Mar;69:38-56. Epub 2018 Nov 9 doi: 10.1016/j.preteyeres.2018.11.003. PMID: 30419340

Recent systematic reviews

Immunomodulatory effects of extracellular vesicles from mesenchymal stromal cells: Implication for therapeutic approach in autoimmune diseases.
Liao HJ, Hsu PN
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Research status and future prospects of extracellular vesicles in primary Sjögren's syndrome.
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Stem Cell Res Ther 2022 Jun 3;13(1):230. doi: 10.1186/s13287-022-02912-1. PMID: 35659085Free PMC Article
Mesenchymal stem cell therapy in hypertrophic and keloid scars.
Bojanic C, To K, Hatoum A, Shea J, Seah KTM, Khan W, Malata CM
Cell Tissue Res 2021 Mar;383(3):915-930. Epub 2021 Jan 2 doi: 10.1007/s00441-020-03361-z. PMID: 33386995Free PMC Article
Cartilage Regeneration in Human with Adipose Tissue-Derived Stem Cells: Current Status in Clinical Implications.
Pak J, Lee JH, Kartolo WA, Lee SH
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