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Abnormal circulating albumin concentration

MedGen UID:
868636
•Concept ID:
C4023036
•
Finding
Synonym: Abnormal albumin level
 
HPO: HP:0012116

Definition

Deviation from normal concentration of albumin in the blood. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal circulating albumin concentration

Professional guidelines

PubMed

Patients with the most advanced rheumatoid arthritis remain with Th1 systemic defects after TNF inhibitors treatment despite clinical improvement.
Kosmaczewska A, Swierkot J, Ciszak L, Szteblich A, Chrobak A, Karabon L, Partyka A, Szechinski J, Wiland P, Frydecka I
Rheumatol Int 2014 Feb;34(2):243-53. Epub 2013 Nov 13 doi: 10.1007/s00296-013-2895-9. PMID: 24221190Free PMC Article

Recent clinical studies

Etiology

Associations of cord blood meta-inflammation and vitamin D with neurodevelopmental delay: A prospective birth cohort study in China.
Wang P, Wu L, Yin WJ, Tao RX, Zhang Y, Li PP, Jiang XM, Shao ZY, Zhu P
Front Immunol 2022;13:1078340. Epub 2023 Jan 4 doi: 10.3389/fimmu.2022.1078340. PMID: 36685522Free PMC Article
C-Reactive Protein and Resistance Exercise in Community Dwelling Old Adults.
Ramel A, Geirsdottir OG, Jonsson PV, Thorsdottiri I
J Nutr Health Aging 2015 Aug;19(7):792-6. doi: 10.1007/s12603-015-0548-2. PMID: 26193865
Increased high sensitive CRP level and its significance in pathogenesis of slow coronary flow.
Barutcu I, Sezgin AT, Sezgin N, Gullu H, Esen AM, Topal E, Ozdemir R, Kosar F, Cehreli S
Angiology 2007 Aug-Sep;58(4):401-7. Epub 2007 Jul 24 doi: 10.1177/0003319707304943. PMID: 17652225
Membrane proteins implicated in long-chain fatty acid uptake by mammalian cells: CD36, FATP and FABPm.
Abumrad N, Coburn C, Ibrahimi A
Biochim Biophys Acta 1999 Oct 18;1441(1):4-13. doi: 10.1016/s1388-1981(99)00137-7. PMID: 10526223
Soluble thrombomodulin antigen in plasma is increased in patients with acute myocardial infarction treated with thrombolytic therapy.
Ohlin AK, Morser J, Ohlin H
Thromb Res 1996 May 15;82(4):313-22. doi: 10.1016/0049-3848(96)00081-3. PMID: 8743727

Diagnosis

Associations of cord blood meta-inflammation and vitamin D with neurodevelopmental delay: A prospective birth cohort study in China.
Wang P, Wu L, Yin WJ, Tao RX, Zhang Y, Li PP, Jiang XM, Shao ZY, Zhu P
Front Immunol 2022;13:1078340. Epub 2023 Jan 4 doi: 10.3389/fimmu.2022.1078340. PMID: 36685522Free PMC Article
Determination of Effective Albumin in Patients With Decompensated Cirrhosis: Clinical and Prognostic Implications.
Baldassarre M, Naldi M, Zaccherini G, Bartoletti M, Antognoli A, Laggetta M, Gagliardi M, Tufoni M, Domenicali M, Waterstradt K, Paterini P, Baldan A, Leoni S, Bartolini M, Viale P, Trevisani F, Bernardi M, Caraceni P
Hepatology 2021 Oct;74(4):2058-2073. Epub 2021 May 26 doi: 10.1002/hep.31798. PMID: 33710623Free PMC Article
Alpha-fetoprotein, a fascinating protein and biomarker in neurology.
Schieving JH, de Vries M, van Vugt JM, Weemaes C, van Deuren M, Nicolai J, Wevers RA, Willemsen MA
Eur J Paediatr Neurol 2014 May;18(3):243-8. Epub 2013 Sep 29 doi: 10.1016/j.ejpn.2013.09.003. PMID: 24120489
Increased high sensitive CRP level and its significance in pathogenesis of slow coronary flow.
Barutcu I, Sezgin AT, Sezgin N, Gullu H, Esen AM, Topal E, Ozdemir R, Kosar F, Cehreli S
Angiology 2007 Aug-Sep;58(4):401-7. Epub 2007 Jul 24 doi: 10.1177/0003319707304943. PMID: 17652225
Alterations in isoprenaline sensitivity in patients with cirrhosis: evidence of abnormality of the sympathetic nervous activity.
Ramond MJ, Comoy E, Lebrec D
Br J Clin Pharmacol 1986 Feb;21(2):191-6. doi: 10.1111/j.1365-2125.1986.tb05174.x. PMID: 3954935Free PMC Article

Therapy

Circulating ACE2 level and zinc/albumin ratio as potential biomarkers for a precision medicine approach to COVID-19.
Benedetti S, Sisti D, Vandini D, Barocci S, Sudano M, Carlotti E, Teng JLL, Zamai L
Adv Biol Regul 2023 Aug;89:100973. Epub 2023 May 23 doi: 10.1016/j.jbior.2023.100973. PMID: 37257289Free PMC Article
The immunological roles in acute-on-chronic liver failure: An update.
Chen P, Wang YY, Chen C, Guan J, Zhu HH, Chen Z
Hepatobiliary Pancreat Dis Int 2019 Oct;18(5):403-411. Epub 2019 Jul 5 doi: 10.1016/j.hbpd.2019.07.003. PMID: 31303562
C-Reactive Protein and Resistance Exercise in Community Dwelling Old Adults.
Ramel A, Geirsdottir OG, Jonsson PV, Thorsdottiri I
J Nutr Health Aging 2015 Aug;19(7):792-6. doi: 10.1007/s12603-015-0548-2. PMID: 26193865
Soluble thrombomodulin antigen in plasma is increased in patients with acute myocardial infarction treated with thrombolytic therapy.
Ohlin AK, Morser J, Ohlin H
Thromb Res 1996 May 15;82(4):313-22. doi: 10.1016/0049-3848(96)00081-3. PMID: 8743727
Intravenous infusion of lipid for the prevention of essential fatty acid deficiency in premature infants.
Gutcher GR, Farrell PM
Am J Clin Nutr 1991 Dec;54(6):1024-8. doi: 10.1093/ajcn/54.6.1024. PMID: 1957817

Prognosis

Circulating ACE2 level and zinc/albumin ratio as potential biomarkers for a precision medicine approach to COVID-19.
Benedetti S, Sisti D, Vandini D, Barocci S, Sudano M, Carlotti E, Teng JLL, Zamai L
Adv Biol Regul 2023 Aug;89:100973. Epub 2023 May 23 doi: 10.1016/j.jbior.2023.100973. PMID: 37257289Free PMC Article
Determination of Effective Albumin in Patients With Decompensated Cirrhosis: Clinical and Prognostic Implications.
Baldassarre M, Naldi M, Zaccherini G, Bartoletti M, Antognoli A, Laggetta M, Gagliardi M, Tufoni M, Domenicali M, Waterstradt K, Paterini P, Baldan A, Leoni S, Bartolini M, Viale P, Trevisani F, Bernardi M, Caraceni P
Hepatology 2021 Oct;74(4):2058-2073. Epub 2021 May 26 doi: 10.1002/hep.31798. PMID: 33710623Free PMC Article
The immunological roles in acute-on-chronic liver failure: An update.
Chen P, Wang YY, Chen C, Guan J, Zhu HH, Chen Z
Hepatobiliary Pancreat Dis Int 2019 Oct;18(5):403-411. Epub 2019 Jul 5 doi: 10.1016/j.hbpd.2019.07.003. PMID: 31303562
Neonatal nephrotic syndrome associated with placental transmission of proinflammatory cytokines.
Assadi F
Pediatr Nephrol 2011 Mar;26(3):469-71. Epub 2010 Nov 27 doi: 10.1007/s00467-010-1700-1. PMID: 21113627
Increased high sensitive CRP level and its significance in pathogenesis of slow coronary flow.
Barutcu I, Sezgin AT, Sezgin N, Gullu H, Esen AM, Topal E, Ozdemir R, Kosar F, Cehreli S
Angiology 2007 Aug-Sep;58(4):401-7. Epub 2007 Jul 24 doi: 10.1177/0003319707304943. PMID: 17652225

Clinical prediction guides

Circulating ACE2 level and zinc/albumin ratio as potential biomarkers for a precision medicine approach to COVID-19.
Benedetti S, Sisti D, Vandini D, Barocci S, Sudano M, Carlotti E, Teng JLL, Zamai L
Adv Biol Regul 2023 Aug;89:100973. Epub 2023 May 23 doi: 10.1016/j.jbior.2023.100973. PMID: 37257289Free PMC Article
Associations of cord blood meta-inflammation and vitamin D with neurodevelopmental delay: A prospective birth cohort study in China.
Wang P, Wu L, Yin WJ, Tao RX, Zhang Y, Li PP, Jiang XM, Shao ZY, Zhu P
Front Immunol 2022;13:1078340. Epub 2023 Jan 4 doi: 10.3389/fimmu.2022.1078340. PMID: 36685522Free PMC Article
Decreased circulating levels of free triiodothyronine in Sepsis children and correlation analysis.
Fu L, Long W, Liu T, Chen Y, Wu S, Li D, Liu K, Gao Y, Luo X
BMC Pediatr 2022 Nov 29;22(1):687. doi: 10.1186/s12887-022-03756-7. PMID: 36447149Free PMC Article
Determination of Effective Albumin in Patients With Decompensated Cirrhosis: Clinical and Prognostic Implications.
Baldassarre M, Naldi M, Zaccherini G, Bartoletti M, Antognoli A, Laggetta M, Gagliardi M, Tufoni M, Domenicali M, Waterstradt K, Paterini P, Baldan A, Leoni S, Bartolini M, Viale P, Trevisani F, Bernardi M, Caraceni P
Hepatology 2021 Oct;74(4):2058-2073. Epub 2021 May 26 doi: 10.1002/hep.31798. PMID: 33710623Free PMC Article
The immunological roles in acute-on-chronic liver failure: An update.
Chen P, Wang YY, Chen C, Guan J, Zhu HH, Chen Z
Hepatobiliary Pancreat Dis Int 2019 Oct;18(5):403-411. Epub 2019 Jul 5 doi: 10.1016/j.hbpd.2019.07.003. PMID: 31303562

Recent systematic reviews

Influence of Statins on Circulating Inflammatory Cytokines in Patients With Abnormal Glucose Homeostasis: A Meta-analysis of Data From Randomized Controlled Trials.
Milajerdi A, Sadeghi A, Mousavi SM, Larijani B, Esmaillzadeh A
Clin Ther 2020 Feb;42(2):e13-e31. Epub 2020 Jan 17 doi: 10.1016/j.clinthera.2019.12.009. PMID: 31955966

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