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Abnormal circulating albumin concentration

MedGen UID:
868636
•Concept ID:
C4023036
•
Finding
Synonym: Abnormal albumin level
 
HPO: HP:0012116

Definition

Deviation from normal concentration of albumin in the blood. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal circulating albumin concentration

Professional guidelines

PubMed

Patients with the most advanced rheumatoid arthritis remain with Th1 systemic defects after TNF inhibitors treatment despite clinical improvement.
Kosmaczewska A, Swierkot J, Ciszak L, Szteblich A, Chrobak A, Karabon L, Partyka A, Szechinski J, Wiland P, Frydecka I
Rheumatol Int 2014 Feb;34(2):243-53. Epub 2013 Nov 13 doi: 10.1007/s00296-013-2895-9. PMID: 24221190Free PMC Article

Recent clinical studies

Etiology

Metabolic dysfunction-associated fatty liver disease and liver function markers are associated with Crohn's disease but not Ulcerative Colitis: a prospective cohort study.
Chen J, Dan L, Tu X, Sun Y, Deng M, Chen X, Hesketh T, Li R, Wang X, Li X
Hepatol Int 2023 Feb;17(1):202-214. Epub 2022 Oct 4 doi: 10.1007/s12072-022-10424-6. PMID: 36194337Free PMC Article
Association of famine exposure and the serum calcium level in healthy Chinese adults.
Yang YY, Zhang D, Ma LY, Hou YF, Bi YF, Xu Y, Xu M, Zhao HY, Sun LH, Tao B, Liu JM
Front Endocrinol (Lausanne) 2022;13:937380. Epub 2022 Aug 9 doi: 10.3389/fendo.2022.937380. PMID: 36017320Free PMC Article
Urinary renin-angiotensin markers in polycystic kidney disease.
Salih M, Bovée DM, Roksnoer LCW, Casteleijn NF, Bakker SJL, Gansevoort RT, Zietse R, Danser AHJ, Hoorn EJ
Am J Physiol Renal Physiol 2017 Oct 1;313(4):F874-F881. Epub 2017 Jul 26 doi: 10.1152/ajprenal.00209.2017. PMID: 28747358
Metabolic syndrome: a marker of patients at high cardiovascular risk.
Lau DC, Yan H, Dhillon B
Can J Cardiol 2006 Feb;22 Suppl B(Suppl B):85B-90B. doi: 10.1016/s0828-282x(06)70992-8. PMID: 16498518Free PMC Article
Serum concentrations and peritoneal loss of growth hormone and growth-hormone-binding protein activity in older adults undergoing continuous ambulatory peritoneal dialysis: comparison with haemodialysis patients and normal subjects.
Kagan A, Zadik Z, Gertler A, Ulman M, Bar-Khayim Y
Nephrol Dial Transplant 1993;8(4):352-6. PMID: 8390011

Diagnosis

Circulating ACE2 level and zinc/albumin ratio as potential biomarkers for a precision medicine approach to COVID-19.
Benedetti S, Sisti D, Vandini D, Barocci S, Sudano M, Carlotti E, Teng JLL, Zamai L
Adv Biol Regul 2023 Aug;89:100973. Epub 2023 May 23 doi: 10.1016/j.jbior.2023.100973. PMID: 37257289Free PMC Article
Adipose tissue macrophage populations and inflammation are associated with systemic inflammation and insulin resistance in obesity.
Kunz HE, Hart CR, Gries KJ, Parvizi M, Laurenti M, Dalla Man C, Moore N, Zhang X, Ryan Z, Polley EC, Jensen MD, Vella A, Lanza IR
Am J Physiol Endocrinol Metab 2021 Jul 1;321(1):E105-E121. Epub 2021 May 17 doi: 10.1152/ajpendo.00070.2021. PMID: 33998291Free PMC Article
Determination of Effective Albumin in Patients With Decompensated Cirrhosis: Clinical and Prognostic Implications.
Baldassarre M, Naldi M, Zaccherini G, Bartoletti M, Antognoli A, Laggetta M, Gagliardi M, Tufoni M, Domenicali M, Waterstradt K, Paterini P, Baldan A, Leoni S, Bartolini M, Viale P, Trevisani F, Bernardi M, Caraceni P
Hepatology 2021 Oct;74(4):2058-2073. Epub 2021 May 26 doi: 10.1002/hep.31798. PMID: 33710623Free PMC Article
Alpha-fetoprotein, a fascinating protein and biomarker in neurology.
Schieving JH, de Vries M, van Vugt JM, Weemaes C, van Deuren M, Nicolai J, Wevers RA, Willemsen MA
Eur J Paediatr Neurol 2014 May;18(3):243-8. Epub 2013 Sep 29 doi: 10.1016/j.ejpn.2013.09.003. PMID: 24120489
Abnormal serum thyroid hormones concentration with healthy functional gland: a review on the metabolic role of thyroid hormones transporter proteins.
Azad RM
Pak J Biol Sci 2011 Mar 1;14(5):313-26. doi: 10.3923/pjbs.2011.313.326. PMID: 21874823

Therapy

Circulating ACE2 level and zinc/albumin ratio as potential biomarkers for a precision medicine approach to COVID-19.
Benedetti S, Sisti D, Vandini D, Barocci S, Sudano M, Carlotti E, Teng JLL, Zamai L
Adv Biol Regul 2023 Aug;89:100973. Epub 2023 May 23 doi: 10.1016/j.jbior.2023.100973. PMID: 37257289Free PMC Article
The immunological roles in acute-on-chronic liver failure: An update.
Chen P, Wang YY, Chen C, Guan J, Zhu HH, Chen Z
Hepatobiliary Pancreat Dis Int 2019 Oct;18(5):403-411. Epub 2019 Jul 5 doi: 10.1016/j.hbpd.2019.07.003. PMID: 31303562
Early Impact of Fontan Operation on Enteric Protein Loss.
Patel JK, Loomes KM, Goldberg DJ, Mercer-Rosa L, Dodds K, Rychik J
Ann Thorac Surg 2016 Mar;101(3):1025-30. Epub 2015 Dec 1 doi: 10.1016/j.athoracsur.2015.09.036. PMID: 26652137Free PMC Article
Clinical evaluation of circulating interleukin-6 and interleukin-10 levels after surgery-induced inflammation.
Miyaoka K, Iwase M, Suzuki R, Kondo G, Watanabe H, Ito D, Nagumo M
J Surg Res 2005 May 15;125(2):144-50. doi: 10.1016/j.jss.2004.12.001. PMID: 15854666
Blood glucose and lipid control as risk factors in the progression of renal damage in type 2 diabetes.
Nosadini R, Tonolo G
J Nephrol 2003 Nov-Dec;16 Suppl 7:S42-7. PMID: 14733300

Prognosis

Circulating ACE2 level and zinc/albumin ratio as potential biomarkers for a precision medicine approach to COVID-19.
Benedetti S, Sisti D, Vandini D, Barocci S, Sudano M, Carlotti E, Teng JLL, Zamai L
Adv Biol Regul 2023 Aug;89:100973. Epub 2023 May 23 doi: 10.1016/j.jbior.2023.100973. PMID: 37257289Free PMC Article
Decreased circulating levels of free triiodothyronine in Sepsis children and correlation analysis.
Fu L, Long W, Liu T, Chen Y, Wu S, Li D, Liu K, Gao Y, Luo X
BMC Pediatr 2022 Nov 29;22(1):687. doi: 10.1186/s12887-022-03756-7. PMID: 36447149Free PMC Article
Determination of Effective Albumin in Patients With Decompensated Cirrhosis: Clinical and Prognostic Implications.
Baldassarre M, Naldi M, Zaccherini G, Bartoletti M, Antognoli A, Laggetta M, Gagliardi M, Tufoni M, Domenicali M, Waterstradt K, Paterini P, Baldan A, Leoni S, Bartolini M, Viale P, Trevisani F, Bernardi M, Caraceni P
Hepatology 2021 Oct;74(4):2058-2073. Epub 2021 May 26 doi: 10.1002/hep.31798. PMID: 33710623Free PMC Article
The immunological roles in acute-on-chronic liver failure: An update.
Chen P, Wang YY, Chen C, Guan J, Zhu HH, Chen Z
Hepatobiliary Pancreat Dis Int 2019 Oct;18(5):403-411. Epub 2019 Jul 5 doi: 10.1016/j.hbpd.2019.07.003. PMID: 31303562
Urinary renin-angiotensin markers in polycystic kidney disease.
Salih M, Bovée DM, Roksnoer LCW, Casteleijn NF, Bakker SJL, Gansevoort RT, Zietse R, Danser AHJ, Hoorn EJ
Am J Physiol Renal Physiol 2017 Oct 1;313(4):F874-F881. Epub 2017 Jul 26 doi: 10.1152/ajprenal.00209.2017. PMID: 28747358

Clinical prediction guides

Circulating ACE2 level and zinc/albumin ratio as potential biomarkers for a precision medicine approach to COVID-19.
Benedetti S, Sisti D, Vandini D, Barocci S, Sudano M, Carlotti E, Teng JLL, Zamai L
Adv Biol Regul 2023 Aug;89:100973. Epub 2023 May 23 doi: 10.1016/j.jbior.2023.100973. PMID: 37257289Free PMC Article
Metabolic dysfunction-associated fatty liver disease and liver function markers are associated with Crohn's disease but not Ulcerative Colitis: a prospective cohort study.
Chen J, Dan L, Tu X, Sun Y, Deng M, Chen X, Hesketh T, Li R, Wang X, Li X
Hepatol Int 2023 Feb;17(1):202-214. Epub 2022 Oct 4 doi: 10.1007/s12072-022-10424-6. PMID: 36194337Free PMC Article
Decreased circulating levels of free triiodothyronine in Sepsis children and correlation analysis.
Fu L, Long W, Liu T, Chen Y, Wu S, Li D, Liu K, Gao Y, Luo X
BMC Pediatr 2022 Nov 29;22(1):687. doi: 10.1186/s12887-022-03756-7. PMID: 36447149Free PMC Article
Determination of Effective Albumin in Patients With Decompensated Cirrhosis: Clinical and Prognostic Implications.
Baldassarre M, Naldi M, Zaccherini G, Bartoletti M, Antognoli A, Laggetta M, Gagliardi M, Tufoni M, Domenicali M, Waterstradt K, Paterini P, Baldan A, Leoni S, Bartolini M, Viale P, Trevisani F, Bernardi M, Caraceni P
Hepatology 2021 Oct;74(4):2058-2073. Epub 2021 May 26 doi: 10.1002/hep.31798. PMID: 33710623Free PMC Article
The immunological roles in acute-on-chronic liver failure: An update.
Chen P, Wang YY, Chen C, Guan J, Zhu HH, Chen Z
Hepatobiliary Pancreat Dis Int 2019 Oct;18(5):403-411. Epub 2019 Jul 5 doi: 10.1016/j.hbpd.2019.07.003. PMID: 31303562

Recent systematic reviews

Influence of Statins on Circulating Inflammatory Cytokines in Patients With Abnormal Glucose Homeostasis: A Meta-analysis of Data From Randomized Controlled Trials.
Milajerdi A, Sadeghi A, Mousavi SM, Larijani B, Esmaillzadeh A
Clin Ther 2020 Feb;42(2):e13-e31. Epub 2020 Jan 17 doi: 10.1016/j.clinthera.2019.12.009. PMID: 31955966

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