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Abnormality of circulating cortisol level

MedGen UID:
868804
Concept ID:
C4023214
Finding
HPO: HP:0011731

Definition

An abnormality of the concentration of cortisol in the blood. [from HPO]

Conditions with this feature

46,XY sex reversal 5
MedGen UID:
414349
Concept ID:
C2751317
Disease or Syndrome

Professional guidelines

PubMed

Scaroni C, Zilio M, Foti M, Boscaro M
Endocr Rev 2017 Jun 1;38(3):189-219. doi: 10.1210/er.2016-1105. PMID: 28368467
Moeller H
Eur J Pediatr 1985 Nov;144(4):370-3. doi: 10.1007/BF00441780. PMID: 4076253
Heaton A, Johnston DG, Haigh JW, Ward MK, Alberti KG, Kerr DN
Clin Sci (Lond) 1985 Oct;69(4):449-57. doi: 10.1042/cs0690449. PMID: 4042546

Recent clinical studies

Etiology

Cheng H, Gao L, Hou B, Feng F, Guo X, Wang Z, Feng M, Xing B, Fan Y
Metabolism 2020 Mar;104:154050. Epub 2019 Dec 18 doi: 10.1016/j.metabol.2019.154050. PMID: 31863780Free PMC Article
Mezzullo M, Fanelli F, Di Dalmazi G, Fazzini A, Ibarra-Gasparini D, Mastroroberto M, Guidi J, Morselli-Labate AM, Pasquali R, Pagotto U, Gambineri A
Psychoneuroendocrinology 2018 May;91:31-40. Epub 2018 Feb 24 doi: 10.1016/j.psyneuen.2018.02.022. PMID: 29522931
Henley DE, Lightman SL
Clin Endocrinol (Oxf) 2014 May;80(5):621-8. Epub 2014 Feb 25 doi: 10.1111/cen.12422. PMID: 24611992
De Backer D, Ortiz JA, Salgado D
Curr Opin Crit Care 2010 Jun;16(3):250-4. doi: 10.1097/MCC.0b013e3283383621. PMID: 20179590
Mantero F, Palermo M, Petrelli MD, Tedde R, Stewart PM, Shackleton CH
Steroids 1996 Apr;61(4):193-6. doi: 10.1016/0039-128x(96)00012-8. PMID: 8732999

Diagnosis

Tharp WG, Breidenstein MW, Friend AF, Bender SP, Raftery D
Physiol Rep 2023 Feb;11(4):e15603. doi: 10.14814/phy2.15603. PMID: 36808704Free PMC Article
Dowsett M, Haynes BP
J Steroid Biochem Mol Biol 2003 Sep;86(3-5):255-63. doi: 10.1016/s0960-0760(03)00365-0. PMID: 14623519
Ellenbogen KA, Morillo CA, Wood MA, Gilligan DM, Eckberg DL, Smith ML
Pacing Clin Electrophysiol 1997 Mar;20(3 Pt 2):788-94. doi: 10.1111/j.1540-8159.1997.tb03905.x. PMID: 9080511
Mantero F, Palermo M, Petrelli MD, Tedde R, Stewart PM, Shackleton CH
Steroids 1996 Apr;61(4):193-6. doi: 10.1016/0039-128x(96)00012-8. PMID: 8732999
Lalezari P, Khorshidi M, Petrosova M
J Pediatr 1986 Nov;109(5):764-9. doi: 10.1016/s0022-3476(86)80690-4. PMID: 3534197

Therapy

Nguyen LS, Rouas-Freiss N, Funck-Brentano C, Leban M, Carosella ED, Touraine P, Varnous S, Bachelot A, Salem JE
Eur J Endocrinol 2019 Nov;181(5):481-488. doi: 10.1530/EJE-19-0379. PMID: 31505456
De Backer D, Ortiz JA, Salgado D
Curr Opin Crit Care 2010 Jun;16(3):250-4. doi: 10.1097/MCC.0b013e3283383621. PMID: 20179590
Dowsett M, Haynes BP
J Steroid Biochem Mol Biol 2003 Sep;86(3-5):255-63. doi: 10.1016/s0960-0760(03)00365-0. PMID: 14623519
Lyons A, Ng C, Fielding K, Hosking D, Selby C, Lawson N
Clin Endocrinol (Oxf) 1997 Oct;47(4):431-8. doi: 10.1046/j.1365-2265.1997.2761083.x. PMID: 9404441
Mantero F, Palermo M, Petrelli MD, Tedde R, Stewart PM, Shackleton CH
Steroids 1996 Apr;61(4):193-6. doi: 10.1016/0039-128x(96)00012-8. PMID: 8732999

Prognosis

Ji E, Weickert CS, Purves-Tyson T, White C, Handelsman DJ, Desai R, O'Donnell M, Liu D, Galletly C, Lenroot R, Weickert TW
Psychoneuroendocrinology 2021 Jan;123:104916. Epub 2020 Oct 14 doi: 10.1016/j.psyneuen.2020.104916. PMID: 33169678
Sienkiewicz E, Magkos F, Aronis KN, Brinkoetter M, Chamberland JP, Chou S, Arampatzi KM, Gao C, Koniaris A, Mantzoros CS
Metabolism 2011 Sep;60(9):1211-21. Epub 2011 Jul 7 doi: 10.1016/j.metabol.2011.05.016. PMID: 21741057
Assadi F
Pediatr Nephrol 2011 Mar;26(3):469-71. Epub 2010 Nov 27 doi: 10.1007/s00467-010-1700-1. PMID: 21113627
Björntorp P, Rosmond R
Drugs 1999;58 Suppl 1:13-8; discussion 75-82. doi: 10.2165/00003495-199958001-00005. PMID: 10576519
Wieck A
Baillieres Clin Obstet Gynaecol 1989 Dec;3(4):857-77. doi: 10.1016/s0950-3552(89)80069-0. PMID: 2700147

Clinical prediction guides

Cheng H, Gao L, Hou B, Feng F, Guo X, Wang Z, Feng M, Xing B, Fan Y
Metabolism 2020 Mar;104:154050. Epub 2019 Dec 18 doi: 10.1016/j.metabol.2019.154050. PMID: 31863780Free PMC Article
Mezzullo M, Fanelli F, Di Dalmazi G, Fazzini A, Ibarra-Gasparini D, Mastroroberto M, Guidi J, Morselli-Labate AM, Pasquali R, Pagotto U, Gambineri A
Psychoneuroendocrinology 2018 May;91:31-40. Epub 2018 Feb 24 doi: 10.1016/j.psyneuen.2018.02.022. PMID: 29522931
Blass BE, Iyer P, Abou-Gharbia M, Childers WE, Gordon JC, Ramanjulu M, Morton G, Arumugam P, Boruwa J, Ellingboe J, Mitra S, Nimmareddy RR, Paliwal S, Rajasekhar J, Shivakumar S, Srivastava P, Tangirala RS, Venkataramanaiah K, Yanamandra M
Bioorg Med Chem Lett 2016 Dec 1;26(23):5825-5829. Epub 2016 Oct 10 doi: 10.1016/j.bmcl.2016.10.016. PMID: 27789139
De Backer D, Ortiz JA, Salgado D
Curr Opin Crit Care 2010 Jun;16(3):250-4. doi: 10.1097/MCC.0b013e3283383621. PMID: 20179590
Ellenbogen KA, Morillo CA, Wood MA, Gilligan DM, Eckberg DL, Smith ML
Pacing Clin Electrophysiol 1997 Mar;20(3 Pt 2):788-94. doi: 10.1111/j.1540-8159.1997.tb03905.x. PMID: 9080511

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