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Abnormal connection of the cardiac segments

MedGen UID:
868895
•Concept ID:
C4023306
•
Anatomical Abnormality
Synonyms: Abnormal connexion of the cardiac segments; Discordant connection of the cardiac segments
 
HPO: HP:0011545

Definition

A deviance in the normal connections between two cardiac segements. [from HPO]

Professional guidelines

PubMed

Aortic treatment in connective tissue disease.
Tinelli G, Ferraresi M, Watkins AC, Hertault A, Soler R, Azzaoui R, Fabre D, Sobocinski J, Haulon S
J Cardiovasc Surg (Torino) 2019 Aug;60(4):518-525. Epub 2018 Jun 26 doi: 10.23736/S0021-9509.18.10443-5. PMID: 29943958
Problems in the diagnosis of discordant atrioventricular with concordant ventriculo-arterial connections: anatomical considerations, surgical management, and long-term outcome.
Laux D, Houyel L, Bajolle F, Raimondi F, Boudjemline Y, Bonnet D
Cardiol Young 2016 Jan;26(1):127-38. Epub 2015 Sep 14 doi: 10.1017/S1047951115000736. PMID: 26365181
Double outlet left ventricle. Morphology, cineangiocardiographic diagnosis and surgical treatment.
Brandt PW, Calder AL, Barratt-Boyes BG, Neutze JM
Am J Cardiol 1976 Dec;38(7):897-909. doi: 10.1016/0002-9149(76)90803-1. PMID: 998525

Recent clinical studies

Etiology

The spectrum of neurodevelopmental, neuromuscular and neurodegenerative disorders due to defective autophagy.
Deneubourg C, Ramm M, Smith LJ, Baron O, Singh K, Byrne SC, Duchen MR, Gautel M, Eskelinen EL, Fanto M, Jungbluth H
Autophagy 2022 Mar;18(3):496-517. Epub 2021 Aug 19 doi: 10.1080/15548627.2021.1943177. PMID: 34130600Free PMC Article
Spontaneous Coronary Artery Dissection: Clinical Outcomes and Risk of Recurrence.
Saw J, Humphries K, Aymong E, Sedlak T, Prakash R, Starovoytov A, Mancini GBJ
J Am Coll Cardiol 2017 Aug 29;70(9):1148-1158. doi: 10.1016/j.jacc.2017.06.053. PMID: 28838364
Brain-heart axis--Review Article.
Manea MM, Comsa M, Minca A, Dragos D, Popa C
J Med Life 2015 Jul-Sep;8(3):266-71. PMID: 26351525Free PMC Article
Updated clinical classification of pulmonary hypertension.
Simonneau G, Gatzoulis MA, Adatia I, Celermajer D, Denton C, Ghofrani A, Gomez Sanchez MA, Krishna Kumar R, Landzberg M, Machado RF, Olschewski H, Robbins IM, Souza R
J Am Coll Cardiol 2013 Dec 24;62(25 Suppl):D34-41. doi: 10.1016/j.jacc.2013.10.029. PMID: 24355639
The nomenclature, definition and classification of cardiac structures in the setting of heterotaxy.
Jacobs JP, Anderson RH, Weinberg PM, Walters HL 3rd, Tchervenkov CI, Del Duca D, Franklin RC, Aiello VD, Béland MJ, Colan SD, Gaynor JW, Krogmann ON, Kurosawa H, Maruszewski B, Stellin G, Elliott MJ
Cardiol Young 2007 Sep;17 Suppl 2:1-28. doi: 10.1017/S1047951107001138. PMID: 18039396

Diagnosis

The spectrum of neurodevelopmental, neuromuscular and neurodegenerative disorders due to defective autophagy.
Deneubourg C, Ramm M, Smith LJ, Baron O, Singh K, Byrne SC, Duchen MR, Gautel M, Eskelinen EL, Fanto M, Jungbluth H
Autophagy 2022 Mar;18(3):496-517. Epub 2021 Aug 19 doi: 10.1080/15548627.2021.1943177. PMID: 34130600Free PMC Article
Spontaneous Coronary Artery Dissection: Clinical Outcomes and Risk of Recurrence.
Saw J, Humphries K, Aymong E, Sedlak T, Prakash R, Starovoytov A, Mancini GBJ
J Am Coll Cardiol 2017 Aug 29;70(9):1148-1158. doi: 10.1016/j.jacc.2017.06.053. PMID: 28838364
Severe Arterial Tortuosity.
Cubero A, Ayala J, Hamzeh G, Cortes A, Udaondo J, Aramendi JI
World J Pediatr Congenit Heart Surg 2017 Mar;8(2):231-234. Epub 2016 Jun 23 doi: 10.1177/2150135116629396. PMID: 27095117
Brain-heart axis--Review Article.
Manea MM, Comsa M, Minca A, Dragos D, Popa C
J Med Life 2015 Jul-Sep;8(3):266-71. PMID: 26351525Free PMC Article
Updated clinical classification of pulmonary hypertension.
Simonneau G, Gatzoulis MA, Adatia I, Celermajer D, Denton C, Ghofrani A, Gomez Sanchez MA, Krishna Kumar R, Landzberg M, Machado RF, Olschewski H, Robbins IM, Souza R
J Am Coll Cardiol 2013 Dec 24;62(25 Suppl):D34-41. doi: 10.1016/j.jacc.2013.10.029. PMID: 24355639

Therapy

Technical Aspects of Branched Thoracic Arch Graft Implantation for Aortic Arch Pathologies.
Spanos K, Panuccio G, Rohlffs F, Heidemann F, Tsilimparis N, Kölbel T
J Endovasc Ther 2020 Oct;27(5):792-800. Epub 2020 May 20 doi: 10.1177/1526602820925443. PMID: 32431247
Spontaneous Coronary Artery Dissection: Clinical Outcomes and Risk of Recurrence.
Saw J, Humphries K, Aymong E, Sedlak T, Prakash R, Starovoytov A, Mancini GBJ
J Am Coll Cardiol 2017 Aug 29;70(9):1148-1158. doi: 10.1016/j.jacc.2017.06.053. PMID: 28838364
Identification of fetal cardiac anatomy and hemodynamics: a novel enhanced screening protocol.
Zhang Y, Cai AL, Ren WD, Guo YJ, Zhang DY, Sun W, Wang Y, Wang L, Qin Y, Huang LP
BMC Pregnancy Childbirth 2016 Jun 30;16:145. doi: 10.1186/s12884-016-0933-9. PMID: 27363399Free PMC Article
Effect of escitalopram on mental stress-induced myocardial ischemia: results of the REMIT trial.
Jiang W, Velazquez EJ, Kuchibhatla M, Samad Z, Boyle SH, Kuhn C, Becker RC, Ortel TL, Williams RB, Rogers JG, O'Connor C
JAMA 2013 May 22;309(20):2139-49. doi: 10.1001/jama.2013.5566. PMID: 23695483Free PMC Article
ECMO and congenital heart disease.
Hines MH
Semin Perinatol 2005 Feb;29(1):34-9. doi: 10.1053/j.semperi.2004.02.001. PMID: 15921150

Prognosis

The spectrum of neurodevelopmental, neuromuscular and neurodegenerative disorders due to defective autophagy.
Deneubourg C, Ramm M, Smith LJ, Baron O, Singh K, Byrne SC, Duchen MR, Gautel M, Eskelinen EL, Fanto M, Jungbluth H
Autophagy 2022 Mar;18(3):496-517. Epub 2021 Aug 19 doi: 10.1080/15548627.2021.1943177. PMID: 34130600Free PMC Article
Spontaneous Coronary Artery Dissection: Clinical Outcomes and Risk of Recurrence.
Saw J, Humphries K, Aymong E, Sedlak T, Prakash R, Starovoytov A, Mancini GBJ
J Am Coll Cardiol 2017 Aug 29;70(9):1148-1158. doi: 10.1016/j.jacc.2017.06.053. PMID: 28838364
Calcium Homeostasis in Health and in Kidney Disease.
Moe SM
Compr Physiol 2016 Sep 15;6(4):1781-1800. doi: 10.1002/cphy.c150052. PMID: 27783859
Nonalternans repolarization variability and arrhythmia - the calcium connection.
Němec J
J Electrocardiol 2016 Nov-Dec;49(6):877-882. Epub 2016 Aug 17 doi: 10.1016/j.jelectrocard.2016.08.003. PMID: 27600096
Brain-heart axis--Review Article.
Manea MM, Comsa M, Minca A, Dragos D, Popa C
J Med Life 2015 Jul-Sep;8(3):266-71. PMID: 26351525Free PMC Article

Clinical prediction guides

Isomerism of the atrial appendages: morphology and terminology.
Frescura C, Ho SY, Giordano M, Thiene G
Cardiovasc Pathol 2020 Jul-Aug;47:107205. Epub 2020 Jan 16 doi: 10.1016/j.carpath.2020.107205. PMID: 32179252
Spontaneous Coronary Artery Dissection: Clinical Outcomes and Risk of Recurrence.
Saw J, Humphries K, Aymong E, Sedlak T, Prakash R, Starovoytov A, Mancini GBJ
J Am Coll Cardiol 2017 Aug 29;70(9):1148-1158. doi: 10.1016/j.jacc.2017.06.053. PMID: 28838364
Modelling and numerical simulation of the in vivo mechanical response of the ascending aortic aneurysm in Marfan syndrome.
García-Herrera CM, Celentano DJ, Herrera EA
Med Biol Eng Comput 2017 Mar;55(3):419-428. Epub 2016 Jun 1 doi: 10.1007/s11517-016-1524-7. PMID: 27250690
Brain-heart axis--Review Article.
Manea MM, Comsa M, Minca A, Dragos D, Popa C
J Med Life 2015 Jul-Sep;8(3):266-71. PMID: 26351525Free PMC Article
Characterization of the connexin45 carboxyl-terminal domain structure and interactions with molecular partners.
Kopanic JL, Al-mugotir MH, Kieken F, Zach S, Trease AJ, Sorgen PL
Biophys J 2014 May 20;106(10):2184-95. doi: 10.1016/j.bpj.2014.03.045. PMID: 24853747Free PMC Article

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