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Agenesis of maxillary premolar

MedGen UID:
869145
•Concept ID:
C4023565
•
Anatomical Abnormality
Synonyms: Absence of maxillary bicuspid; Absence of maxillary premolar; Absence of upper premolar; Agenesis of maxillary bicuspid; Failure of development of maxillary bicuspid; Failure of development of maxillary premolar; Missing maxillary premolar; Missing upper bicuspid; Missing upper premolar
 
HPO: HP:0011052

Definition

Agenesis of maxillary premolar. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAgenesis of maxillary premolar

Professional guidelines

PubMed

Genotype-phenotype analysis of selective failure of tooth eruption-A systematic review.
Guo X, Duan X
Clin Genet 2023 Sep;104(3):287-297. Epub 2023 Jul 13 doi: 10.1111/cge.14400. PMID: 37448157
Hypodontia: An Update on Its Etiology, Classification, and Clinical Management.
Al-Ani AH, Antoun JS, Thomson WM, Merriman TR, Farella M
Biomed Res Int 2017;2017:9378325. Epub 2017 Mar 19 doi: 10.1155/2017/9378325. PMID: 28401166Free PMC Article
Management of missing maxillary anterior teeth with emphasis on autotransplantation.
Zachrisson BU, Stenvik A, Haanaes HR
Am J Orthod Dentofacial Orthop 2004 Sep;126(3):284-8. doi: 10.1016/S0889540604005244. PMID: 15356486

Recent clinical studies

Etiology

Patterns of nonsyndromic tooth agenesis and sexual dimorphism.
Kanchanasevee C, Chantarangsu S, Pittayapat P, Porntaveetus T
BMC Oral Health 2023 Jan 23;23(1):37. doi: 10.1186/s12903-023-02753-1. PMID: 36691053Free PMC Article
Symmetry of crown widths in subjects with unilateral maxillary lateral incisor agenesis.
Gorucu-Coskuner H, Atik E, Akarsu-Guven B
J Orofac Orthop 2022 Sep;83(5):325-331. Epub 2021 Apr 14 doi: 10.1007/s00056-021-00293-3. PMID: 33852040
Prevalence of Premature Eruption and Agenesis of Premolars in Turkish Children: A Retrospective Study.
Koc N, Ballikaya E, Cehreli ZC
J Clin Pediatr Dent 2021 Jan 1;45(1):58-62. doi: 10.17796/1053-4625-45.1.11. PMID: 33690831
Prevalence of hypodontia and associated factors: a systematic review and meta-analysis.
Khalaf K, Miskelly J, Voge E, Macfarlane TV
J Orthod 2014 Dec;41(4):299-316. doi: 10.1179/1465313314Y.0000000116. PMID: 25404667
TEMPORARY REMOVAL: Orthodontic treatment for a patient with a unilateral cleft lip and palate and congenitally missing maxillary lateral incisors and left second premolar.
Tai K, Park JH, Okadakage S, Mori S, Sato Y
Am J Orthod Dentofacial Orthop 2012 Mar;141(3):363-373. doi: 10.1016/j.ajodo.2010.04.037. PMID: 22381497

Diagnosis

Genotype-phenotype analysis of selective failure of tooth eruption-A systematic review.
Guo X, Duan X
Clin Genet 2023 Sep;104(3):287-297. Epub 2023 Jul 13 doi: 10.1111/cge.14400. PMID: 37448157
Prevalence and patterns of permanent tooth agenesis in individuals with Down syndrome: a meta-analysis.
Palaska PK, Antonarakis GS
Eur J Oral Sci 2016 Aug;124(4):317-28. Epub 2016 Jun 17 doi: 10.1111/eos.12282. PMID: 27311636
Improperly formed maxillary teeth.
Kuklani RM, Supancic JS, Cohen DM, Bhattacharyya I
J Am Dent Assoc 2010 Nov;141(11):1346-50. doi: 10.14219/jada.archive.2010.0079. PMID: 21037192
Canine transposition.
Tseng YC, Chang HP, Chou TM
Kaohsiung J Med Sci 2005 Oct;21(10):441-7. doi: 10.1016/S1607-551X(09)70148-2. PMID: 16302446
Taurodontism in premolars.
Llamas R, Jimenez-Planas A
Oral Surg Oral Med Oral Pathol 1993 Apr;75(4):501-5. doi: 10.1016/0030-4220(93)90179-8. PMID: 8464617

Therapy

Association between maxillary canine impaction and other dental anomalies: radiological study of a mixed dentition children's cohort from an orthodontic clinic.
Kolokitha OE, Balli D, Zarkadi AE, Gizani S
Eur Arch Paediatr Dent 2023 Jun;24(3):401-407. Epub 2023 Apr 13 doi: 10.1007/s40368-023-00798-y. PMID: 37046044Free PMC Article
Tooth-borne versus bone-borne rapid maxillary expansion for transverse maxillary deficiency: A systematic review.
Khosravi M, Ugolini A, Miresmaeili A, Mirzaei H, Shahidi-Zandi V, Soheilifar S, Karami M, Mahmoudzadeh M
Int Orthod 2019 Sep;17(3):425-436. Epub 2019 Jul 4 doi: 10.1016/j.ortho.2019.06.003. PMID: 31280998
The "radiculous" maxillary premolar: recognition, diagnosis, and case report of surgical intervention.
Goon WW
Northwest Dent 1993 Mar-Apr;72(2):31-3. PMID: 8332442
Prevalence of hypodontia and developmental malformation of permanent teeth in Saudi Arabian schoolchildren.
al-Emran S
Br J Orthod 1990 May;17(2):115-8. doi: 10.1179/bjo.17.2.115. PMID: 2192761
Endodontic therapy for dens invaginatus in a maxillary second premolar.
Rotstein I, Stabholz A, Friedman S
Oral Surg Oral Med Oral Pathol 1987 Feb;63(2):237-40. doi: 10.1016/0030-4220(87)90320-3. PMID: 3469607

Prognosis

Hypodontia: An Update on Its Etiology, Classification, and Clinical Management.
Al-Ani AH, Antoun JS, Thomson WM, Merriman TR, Farella M
Biomed Res Int 2017;2017:9378325. Epub 2017 Mar 19 doi: 10.1155/2017/9378325. PMID: 28401166Free PMC Article
Prevalence and patterns of permanent tooth agenesis in individuals with Down syndrome: a meta-analysis.
Palaska PK, Antonarakis GS
Eur J Oral Sci 2016 Aug;124(4):317-28. Epub 2016 Jun 17 doi: 10.1111/eos.12282. PMID: 27311636
Retrospective Study of Association between Displacement of Maxillary Canine and Tooth Agenesis.
Jang E, Lee K, An S, Song J, Ra J
J Clin Pediatr Dent 2015 Fall;39(5):488-92. doi: 10.17796/1053-4628-39.5.488. PMID: 26551375
TEMPORARY REMOVAL: Orthodontic treatment for a patient with a unilateral cleft lip and palate and congenitally missing maxillary lateral incisors and left second premolar.
Tai K, Park JH, Okadakage S, Mori S, Sato Y
Am J Orthod Dentofacial Orthop 2012 Mar;141(3):363-373. doi: 10.1016/j.ajodo.2010.04.037. PMID: 22381497
Endodontic implications of the variability of the root canal systems of posterior teeth.
Biggs JT, Benenati FW
J Okla Dent Assoc 1995 Winter;85(3):25-9. PMID: 9526234

Clinical prediction guides

Closure of maxillary lateral incisor agenesis space in unilateral cleft lip and palate: a digital model assessment.
Manfio ASC, Garib D, Flores-Mir C, Lauris JRP, Teixeira R, Almeida ALPF
Dental Press J Orthod 2023;28(1):e2321331. Epub 2023 Apr 14 doi: 10.1590/2177-6709.28.1.e2321331.oar. PMID: 37075417Free PMC Article
Patterns of nonsyndromic tooth agenesis and sexual dimorphism.
Kanchanasevee C, Chantarangsu S, Pittayapat P, Porntaveetus T
BMC Oral Health 2023 Jan 23;23(1):37. doi: 10.1186/s12903-023-02753-1. PMID: 36691053Free PMC Article
Hypodontia: An Update on Its Etiology, Classification, and Clinical Management.
Al-Ani AH, Antoun JS, Thomson WM, Merriman TR, Farella M
Biomed Res Int 2017;2017:9378325. Epub 2017 Mar 19 doi: 10.1155/2017/9378325. PMID: 28401166Free PMC Article
Endodontic implications of the variability of the root canal systems of posterior teeth.
Biggs JT, Benenati FW
J Okla Dent Assoc 1995 Winter;85(3):25-9. PMID: 9526234
Taurodontism in premolars.
Llamas R, Jimenez-Planas A
Oral Surg Oral Med Oral Pathol 1993 Apr;75(4):501-5. doi: 10.1016/0030-4220(93)90179-8. PMID: 8464617

Recent systematic reviews

Genotype-phenotype analysis of selective failure of tooth eruption-A systematic review.
Guo X, Duan X
Clin Genet 2023 Sep;104(3):287-297. Epub 2023 Jul 13 doi: 10.1111/cge.14400. PMID: 37448157
Atypical Radicular Anatomy in Permanent Human Teeth: A Systematic Review.
Nino-Barrera J, Alzate-Mendoza D, Olaya-Abril C, Gamboa-Martinez LF, Guamán-Laverde M, Lagos-Rosero N, Romero-Diaz AC, Duran N, Vanegas-Hoyose L
Crit Rev Biomed Eng 2022;50(1):19-34. doi: 10.1615/CritRevBiomedEng.2022043742. PMID: 35997108
Tooth-borne versus bone-borne rapid maxillary expansion for transverse maxillary deficiency: A systematic review.
Khosravi M, Ugolini A, Miresmaeili A, Mirzaei H, Shahidi-Zandi V, Soheilifar S, Karami M, Mahmoudzadeh M
Int Orthod 2019 Sep;17(3):425-436. Epub 2019 Jul 4 doi: 10.1016/j.ortho.2019.06.003. PMID: 31280998
Permanent tooth agenesis in individuals with non-syndromic Robin sequence: a systematic review and meta-analysis.
Antonarakis GS, Palaska PK, Suri S
Orthod Craniofac Res 2017 Nov;20(4):216-226. Epub 2017 Oct 13 doi: 10.1111/ocr.12204. PMID: 29027749
Prevalence of hypodontia and associated factors: a systematic review and meta-analysis.
Khalaf K, Miskelly J, Voge E, Macfarlane TV
J Orthod 2014 Dec;41(4):299-316. doi: 10.1179/1465313314Y.0000000116. PMID: 25404667

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