U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormality of the common coagulation pathway

MedGen UID:
869187
•Concept ID:
C4023609
•
Anatomical Abnormality
HPO: HP:0010990

Definition

An abnormality of blood coagulation, common pathway. [from HPO]

Professional guidelines

PubMed

VEGF-targeting drugs for the treatment of retinal neovascularization in diabetic retinopathy.
Arrigo A, Aragona E, Bandello F
Ann Med 2022 Dec;54(1):1089-1111. doi: 10.1080/07853890.2022.2064541. PMID: 35451900Free PMC Article
Sickle cell disease: current treatment and emerging therapies.
Neumayr LD, Hoppe CC, Brown C
Am J Manag Care 2019 Nov;25(18 Suppl):S335-S343. PMID: 31809007
Clinical Evaluation of Bleeding and Bruising in Primary Care.
Neutze D, Roque J
Am Fam Physician 2016 Feb 15;93(4):279-86. PMID: 26926815

Recent clinical studies

Therapy

Isolated Prolongation of Activated Partial Thromboplastin Time: Not Just Bleeding Risk!
Santoro RC, Molinari AC, Leotta M, Martini T
Medicina (Kaunas) 2023 Jun 17;59(6) doi: 10.3390/medicina59061169. PMID: 37374373Free PMC Article
VEGF-targeting drugs for the treatment of retinal neovascularization in diabetic retinopathy.
Arrigo A, Aragona E, Bandello F
Ann Med 2022 Dec;54(1):1089-1111. doi: 10.1080/07853890.2022.2064541. PMID: 35451900Free PMC Article
Sickle cell disease: current treatment and emerging therapies.
Neumayr LD, Hoppe CC, Brown C
Am J Manag Care 2019 Nov;25(18 Suppl):S335-S343. PMID: 31809007
Pathogenesis and diagnosis of disseminated intravascular coagulation.
Levi M
Int J Lab Hematol 2018 May;40 Suppl 1:15-20. doi: 10.1111/ijlh.12830. PMID: 29741245
Coagulation in sepsis.
Amaral A, Opal SM, Vincent JL
Intensive Care Med 2004 Jun;30(6):1032-40. Epub 2004 May 18 doi: 10.1007/s00134-004-2291-8. PMID: 15148567

Prognosis

Metabolome subtyping reveals multi-omics characteristics and biological heterogeneity in major psychiatric disorders.
Hao M, Qin Y, Li Y, Tang Y, Ma Z, Tan J, Jin L, Wang F, Gong X
Psychiatry Res 2023 Dec;330:115605. Epub 2023 Nov 13 doi: 10.1016/j.psychres.2023.115605. PMID: 38006718
A Review of Coagulation Abnormalities of Autoimmune Acquired Factor V Deficiency with a Focus on Japan.
Ichinose A, Osaki T, Souri M
Semin Thromb Hemost 2022 Mar;48(2):206-218. Epub 2021 Dec 23 doi: 10.1055/s-0041-1740149. PMID: 34942668
Platelet gene expression and function in patients with COVID-19.
Manne BK, Denorme F, Middleton EA, Portier I, Rowley JW, Stubben C, Petrey AC, Tolley ND, Guo L, Cody M, Weyrich AS, Yost CC, Rondina MT, Campbell RA
Blood 2020 Sep 10;136(11):1317-1329. doi: 10.1182/blood.2020007214. PMID: 32573711Free PMC Article
The Role of Abnormal Hemostasis and Fibrinolysis in Morbidity and Mortality of Acute Promyelocytic Leukemia.
Kwaan HC, Weiss I, Tallman MS
Semin Thromb Hemost 2019 Sep;45(6):612-621. Epub 2019 Aug 1 doi: 10.1055/s-0039-1693478. PMID: 31370070
Novel therapeutic approaches for pulmonary fibrosis.
Datta A, Scotton CJ, Chambers RC
Br J Pharmacol 2011 May;163(1):141-72. doi: 10.1111/j.1476-5381.2011.01247.x. PMID: 21265830Free PMC Article

Clinical prediction guides

Metabolome subtyping reveals multi-omics characteristics and biological heterogeneity in major psychiatric disorders.
Hao M, Qin Y, Li Y, Tang Y, Ma Z, Tan J, Jin L, Wang F, Gong X
Psychiatry Res 2023 Dec;330:115605. Epub 2023 Nov 13 doi: 10.1016/j.psychres.2023.115605. PMID: 38006718
Coagulation Abnormalities and Thrombosis in Patients Infected With SARS-CoV-2 and Other Pandemic Viruses.
Mackman N, Antoniak S, Wolberg AS, Kasthuri R, Key NS
Arterioscler Thromb Vasc Biol 2020 Sep;40(9):2033-2044. Epub 2020 Jul 13 doi: 10.1161/ATVBAHA.120.314514. PMID: 32657623Free PMC Article
Pathogenesis and diagnosis of disseminated intravascular coagulation.
Levi M
Int J Lab Hematol 2018 May;40 Suppl 1:15-20. doi: 10.1111/ijlh.12830. PMID: 29741245
Common and specific effects of TIE2 mutations causing venous malformations.
Nätynki M, Kangas J, Miinalainen I, Sormunen R, Pietilä R, Soblet J, Boon LM, Vikkula M, Limaye N, Eklund L
Hum Mol Genet 2015 Nov 15;24(22):6374-89. Epub 2015 Aug 28 doi: 10.1093/hmg/ddv349. PMID: 26319232Free PMC Article
Hematologic effects and complications of snake envenoming.
Berling I, Isbister GK
Transfus Med Rev 2015 Apr;29(2):82-9. Epub 2014 Dec 18 doi: 10.1016/j.tmrv.2014.09.005. PMID: 25556574

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...