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Abnormality of the proximal humeral epiphysis

MedGen UID:: 869349
•Concept ID:: C4023775
•: Anatomical Abnormality

Synonym:	Abnormality of the end part of the innermost long bone in upper arm

HPO:	HP:0010598

Definition

Any abnormality of the proximal epiphysis of the humerus. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVAbnormality of the proximal humeral epiphysis

Abnormal appendicular skeleton morphology
- Abnormal long bone morphology
  - Abnormal epiphysis morphology
    - Abnormal limb epiphysis morphology
      - Abnormal upper limb epiphysis morphology
        Abnormality of the humeral epiphysis
        Abnormality of the proximal humeral epiphysis

Recent clinical studies

Etiology

Proximal humerus fractures in children and adolescents.

Lefèvre Y, Journeau P, Angelliaume A, Bouty A, Dobremez E
Orthop Traumatol Surg Res 2014 Feb;100(1 Suppl):S149-56. Epub 2014 Jan 4 doi: 10.1016/j.otsr.2013.06.010. PMID: 24394917

Physeal injuries of the proximal humerus: long-term results in seventy two patients.

Binder H, Schurz M, Aldrian S, Fialka C, Vécsei V
Int Orthop 2011 Oct;35(10):1497-502. Epub 2011 May 24 doi: 10.1007/s00264-011-1277-8. PMID: 21607606 Free PMC Article

Abnormalities of the axial and proximal appendicular skeleton in adults with Laron syndrome (growth hormone insensitivity).

Kornreich L, Konen O, Schwarz M, Siegel Y, Horev G, Hershkovitz I, Laron Z
Skeletal Radiol 2008 Feb;37(2):153-60. Epub 2007 Nov 9 doi: 10.1007/s00256-007-0402-7. PMID: 17992526

Long-term effects of neonatal bone and joint infection on adjacent growth plates.

Peters W, Irving J, Letts M
J Pediatr Orthop 1992 Nov-Dec;12(6):806-10. doi: 10.1097/01241398-199211000-00020. PMID: 1452755

Little league shoulder: osteochondrosis of the proximal humeral epiphysis in boy baseball pitchers.

Adams JE
Calif Med 1966 Jul;105(1):22-5. PMID: 5946993 Free PMC Article

See all (9)

Diagnosis

Slipped Capital Femoral Epiphysis Associated With Vitamin C Deficiency in a 7-year-old Boy.

Nazeer M, Ravindran R, Katragadda BC, Muhammed EN, Titus S, Muhammed MN
J Am Acad Orthop Surg Glob Res Rev 2021 May 6;5(5) doi: 10.5435/JAAOSGlobal-D-21-00012. PMID: 33961586 Free PMC Article

Proximal humerus fractures in children and adolescents.

Lefèvre Y, Journeau P, Angelliaume A, Bouty A, Dobremez E
Orthop Traumatol Surg Res 2014 Feb;100(1 Suppl):S149-56. Epub 2014 Jan 4 doi: 10.1016/j.otsr.2013.06.010. PMID: 24394917

Physeal injuries of the proximal humerus: long-term results in seventy two patients.

Binder H, Schurz M, Aldrian S, Fialka C, Vécsei V
Int Orthop 2011 Oct;35(10):1497-502. Epub 2011 May 24 doi: 10.1007/s00264-011-1277-8. PMID: 21607606 Free PMC Article

Epiphyseal dysplasia and other skeletal anomalies in a patient with the 6p25 microdeletion syndrome.

Kannu P, Oei P, Slater HR, Khammy O, Aftimos S
Am J Med Genet A 2006 Sep 15;140(18):1955-9. doi: 10.1002/ajmg.a.31411. PMID: 16906570

Congenital and developmental anomalies of the shoulder girdle.

Samilson RL
Orthop Clin North Am 1980 Apr;11(2):219-31. PMID: 7001305

See all (14)

Therapy

Physeal injuries of the proximal humerus: long-term results in seventy two patients.

Binder H, Schurz M, Aldrian S, Fialka C, Vécsei V
Int Orthop 2011 Oct;35(10):1497-502. Epub 2011 May 24 doi: 10.1007/s00264-011-1277-8. PMID: 21607606 Free PMC Article

See all (1)

Prognosis

The Immature Pediatric Appendicular Skeleton.

Nguyen JC, Caine D
Semin Musculoskelet Radiol 2024 Aug;28(4):361-374. Epub 2024 Jul 29 doi: 10.1055/s-0044-1786151. PMID: 39074720

Proximal humerus fractures in children and adolescents.

Lefèvre Y, Journeau P, Angelliaume A, Bouty A, Dobremez E
Orthop Traumatol Surg Res 2014 Feb;100(1 Suppl):S149-56. Epub 2014 Jan 4 doi: 10.1016/j.otsr.2013.06.010. PMID: 24394917

Physeal injuries of the proximal humerus: long-term results in seventy two patients.

Binder H, Schurz M, Aldrian S, Fialka C, Vécsei V
Int Orthop 2011 Oct;35(10):1497-502. Epub 2011 May 24 doi: 10.1007/s00264-011-1277-8. PMID: 21607606 Free PMC Article

Stress fracture of the proximal humeral epiphysis in an elite junior badminton player.

Boyd KT, Batt ME
Br J Sports Med 1997 Sep;31(3):252-3. doi: 10.1136/bjsm.31.3.252. PMID: 9298564 Free PMC Article

Long-term effects of neonatal bone and joint infection on adjacent growth plates.

Peters W, Irving J, Letts M
J Pediatr Orthop 1992 Nov-Dec;12(6):806-10. doi: 10.1097/01241398-199211000-00020. PMID: 1452755

See all (6)

Clinical prediction guides

The Immature Pediatric Appendicular Skeleton.

Nguyen JC, Caine D
Semin Musculoskelet Radiol 2024 Aug;28(4):361-374. Epub 2024 Jul 29 doi: 10.1055/s-0044-1786151. PMID: 39074720

Poly-epiphyseal overgrowth: description of a previously unreported skeletal dysplasia.

Pazzaglia UE, Beluffi G, Marchi A, Bozzola M, Savasta S, Bonaspetti G
Pediatr Radiol 2007 Oct;37(10):1025-30. Epub 2007 Jul 26 doi: 10.1007/s00247-007-0532-z. PMID: 17653707

Long-term effects of neonatal bone and joint infection on adjacent growth plates.

Peters W, Irving J, Letts M
J Pediatr Orthop 1992 Nov-Dec;12(6):806-10. doi: 10.1097/01241398-199211000-00020. PMID: 1452755

Epiphyseal chondroblastoma of bone. Long-term effects on skeletal growth and articular function in 15 cases treated surgically.

Caterini R, Manili M, Spinelli M, Santori FS, Ippolito E
Arch Orthop Trauma Surg 1992;111(6):327-32. doi: 10.1007/BF00420060. PMID: 1449941

Little league shoulder: osteochondrosis of the proximal humeral epiphysis in boy baseball pitchers.

Adams JE
Calif Med 1966 Jul;105(1):22-5. PMID: 5946993 Free PMC Article

See all (5)