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Asymmetry of the mouth

MedGen UID:
869725
Concept ID:
C4024153
Finding
Synonyms: Asymmetry of oral cavity; Canted mouth; Crooked mouth; Tilted mouth; Uneven mouth
 
HPO: HP:0009941

Definition

The presence of an asymmetric mouth. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAsymmetry of the mouth

Conditions with this feature

Symphalangism-brachydactyly syndrome
MedGen UID:
90977
Concept ID:
C0342282
Disease or Syndrome
Multiple synostoses syndrome is characterized by multiple joint fusions, usually commencing in the hands, conductive deafness, and characteristic facial features, including a broad, tubular-shaped nose and a thin upper vermilion. Other features include brachydactyly, hypoplastic or absent middle phalanges, radial head dislocation, and pectus carinatum (summary by Takahashi et al., 2001). Genetic Heterogeneity of Multiple Synostoses Syndrome Other forms of multiple synostoses syndrome include SYNS2 (610017), caused by mutation in the GDF5 gene (601146) on chromosome 20q11; SYNS3 (612961), caused by mutation in the FGF9 gene (600921) on chromosome 13q12; and SYNS4 (617898), caused by mutation in the GDF6 gene (601147) on chromosome 8q22.

Professional guidelines

PubMed

Zhou H, Liao C, Hu J, Fei W
Br J Oral Maxillofac Surg 2018 Jan;56(1):19-23. Epub 2017 Feb 27 doi: 10.1016/j.bjoms.2016.09.023. PMID: 28249702
Smith KS, Henry BT, Scott MA
Oral Maxillofac Surg Clin North Am 2016 May;28(2):169-76. doi: 10.1016/j.coms.2016.01.003. PMID: 27150304
Shroff B, Siegel SM
Semin Orthod 1998 Sep;4(3):165-79. doi: 10.1016/s1073-8746(98)80018-2. PMID: 9807153

Recent clinical studies

Etiology

Shetty SR, Al-Bayatti S, AlKawas S, Talaat W, Narasimhan S, Gaballah K, Al-Rawi N, Alsaegh M, Madiyal A, Balan P, Kamath V
Int Dent J 2022 Dec;72(6):797-804. Epub 2022 Aug 2 doi: 10.1016/j.identj.2022.06.019. PMID: 35931561Free PMC Article
Abba M, Abramson A, Tunis TS, Roitblat Y, Shilco P, Vaiman M
J Oral Maxillofac Surg 2022 May;80(5):913-919. Epub 2022 Jan 13 doi: 10.1016/j.joms.2022.01.007. PMID: 35143776
Oxilia G, Menghi Sartorio JC, Bortolini E, Zampirolo G, Papini A, Boggioni M, Martini S, Marciani F, Arrighi S, Figus C, Marciani G, Romandini M, Silvestrini S, Pedrosi ME, Mori T, Riga A, Kullmer O, Sarig R, Fiorenza L, Giganti M, Sorrentino R, Belcastro MG, Cecchi JM, Benazzi S
Am J Phys Anthropol 2021 Aug;175(4):847-864. Epub 2021 May 11 doi: 10.1002/ajpa.24293. PMID: 33973654Free PMC Article
Jodeh DS, Soni S, Cray JJ, Rottgers SA
Cleft Palate Craniofac J 2021 May;58(5):539-545. Epub 2020 Sep 30 doi: 10.1177/1055665620962365. PMID: 32996328
Kotlarek KJ, Pelland CM, Blemker SS, Jaskolka MS, Fang X, Perry JL
J Speech Lang Hear Res 2020 May 22;63(5):1317-1325. Epub 2020 May 13 doi: 10.1044/2020_JSLHR-19-00240. PMID: 32402223Free PMC Article

Diagnosis

Shetty SR, Al-Bayatti S, AlKawas S, Talaat W, Narasimhan S, Gaballah K, Al-Rawi N, Alsaegh M, Madiyal A, Balan P, Kamath V
Int Dent J 2022 Dec;72(6):797-804. Epub 2022 Aug 2 doi: 10.1016/j.identj.2022.06.019. PMID: 35931561Free PMC Article
Schooling CN, Jamie Healey T, McDonough HE, French SJ, McDermott CJ, Shaw PJ, Kadirkamanathan V, Alix JJP
Physiol Meas 2021 Jan 9;41(12):125008. doi: 10.1088/1361-6579/abcb9b. PMID: 33207324
Araújo TM, Caldas LD
Dental Press J Orthod 2019 Aug 1;24(3):88-98. doi: 10.1590/2177-6709.24.3.088-098.bbo. PMID: 31390455Free PMC Article
Schimmel M, Ono T, Lam OL, Müller F
J Oral Rehabil 2017 Apr;44(4):313-326. Epub 2017 Mar 1 doi: 10.1111/joor.12486. PMID: 28128465
Brancati F, Sarkozy A, Dallapiccola B
Orphanet J Rare Dis 2006 Dec 12;1:50. doi: 10.1186/1750-1172-1-50. PMID: 17163996Free PMC Article

Therapy

Jokar M, Namavari N, Moshiri SA, Jahromi HK, Rahmanian V
Cancer Rep (Hoboken) 2023 Jun;6(6):e1836. Epub 2023 May 16 doi: 10.1002/cnr2.1836. PMID: 37191384Free PMC Article
Moradi A, Shirazi A
Plast Reconstr Surg 2022 Apr 1;149(4):850-857. doi: 10.1097/PRS.0000000000008967. PMID: 35139057
Wollina U, Goldman A
Dermatol Ther 2020 Nov;33(6):e14231. Epub 2020 Sep 7 doi: 10.1111/dth.14231. PMID: 32852076
Wang W, Yang Y, Zhang W, Wu W
Oral Oncol 2014 Apr;50(4):276-81. Epub 2014 Jan 2 doi: 10.1016/j.oraloncology.2013.12.014. PMID: 24389399
Schmidt CJ, Tatum SA
Curr Opin Otolaryngol Head Neck Surg 2006 Aug;14(4):254-9. doi: 10.1097/01.moo.0000233596.68928.39. PMID: 16832182

Prognosis

Jokar M, Namavari N, Moshiri SA, Jahromi HK, Rahmanian V
Cancer Rep (Hoboken) 2023 Jun;6(6):e1836. Epub 2023 May 16 doi: 10.1002/cnr2.1836. PMID: 37191384Free PMC Article
Abba M, Abramson A, Roitblat Y, Vaiman M
J Oral Maxillofac Surg 2022 Dec;80(12):1996-2002. Epub 2022 Sep 9 doi: 10.1016/j.joms.2022.09.001. PMID: 36207007
Durmuş Kocaaslan N, Karadede Ünal B, Çavuş Özkan M, Karadede B, Çelebiler Ö
Ulus Travma Acil Cerrahi Derg 2022 Jan;28(1):99-106. doi: 10.14744/tjtes.2020.94992. PMID: 34967439Free PMC Article
Kwon TG, Miloro M, Xi T, Han MD
J Oral Maxillofac Surg 2020 Aug;78(8):1356-1365. Epub 2020 Apr 18 doi: 10.1016/j.joms.2020.04.011. PMID: 32428460
Schmitz J, Fraenz C, Schlüter C, Friedrich P, Kumsta R, Moser D, Güntürkün O, Genç E, Ocklenburg S
Psychiatry Res Neuroimaging 2019 Dec 30;294:110991. Epub 2019 Oct 25 doi: 10.1016/j.pscychresns.2019.110991. PMID: 31683112

Clinical prediction guides

Gatti JE
Plast Reconstr Surg 2023 Oct 1;152(4):765-772. Epub 2023 Mar 7 doi: 10.1097/PRS.0000000000010361. PMID: 36877617
Schooling CN, Jamie Healey T, McDonough HE, French SJ, McDermott CJ, Shaw PJ, Kadirkamanathan V, Alix JJP
Physiol Meas 2021 Jan 9;41(12):125008. doi: 10.1088/1361-6579/abcb9b. PMID: 33207324
Oliveira PLE, Motta A, Pithon M, Mucha J
Int J Esthet Dent 2018;13(4):494-514. PMID: 30302439
Jones NS, Raghavan U
J Laryngol Otol Suppl 2009;(32):1-38. doi: 10.1017/s0022215109005234. PMID: 19845187
Brancati F, Sarkozy A, Dallapiccola B
Orphanet J Rare Dis 2006 Dec 12;1:50. doi: 10.1186/1750-1172-1-50. PMID: 17163996Free PMC Article

Recent systematic reviews

Jokar M, Namavari N, Moshiri SA, Jahromi HK, Rahmanian V
Cancer Rep (Hoboken) 2023 Jun;6(6):e1836. Epub 2023 May 16 doi: 10.1002/cnr2.1836. PMID: 37191384Free PMC Article
Poorna T A, Alagarsamy R, Ek J, Singh AK, Lal B, Roychoudhury A
Oral Surg Oral Med Oral Pathol Oral Radiol 2023 Jun;135(6):732-745. Epub 2022 Oct 1 doi: 10.1016/j.oooo.2022.09.039. PMID: 36529674
Zapata-Soria M, Cabrera-Martos I, López-López L, Ortiz-Rubio A, Granados-Santiago M, Ríos-Asín I, Valenza MC
Int J Environ Res Public Health 2022 Dec 30;20(1) doi: 10.3390/ijerph20010657. PMID: 36613028Free PMC Article
Palla B, Burian E, Fliefel R, Otto S
Clin Oral Investig 2018 Jan;22(1):1-27. Epub 2017 Jun 14 doi: 10.1007/s00784-017-2124-0. PMID: 28616750
Schimmel M, Ono T, Lam OL, Müller F
J Oral Rehabil 2017 Apr;44(4):313-326. Epub 2017 Mar 1 doi: 10.1111/joor.12486. PMID: 28128465

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