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Synostosis of thumb phalanx

MedGen UID:
869832
•Concept ID:
C4024263
•
Anatomical Abnormality
Synonym: Fusion of thumb bone
 
HPO: HP:0009635

Definition

Fusion of a phalanx of the thumb with another bone. [from HPO]

Professional guidelines

PubMed

Central Coalition Osteotomy of Phalangeal Synostoses in the Management of the Type III Apert Hand.
Theman TA, Upton J, Taghinia AH, Firriolo JM, Nuzzi LC, Labow BI
J Hand Surg Am 2018 Nov;43(11):1042.e1-1042.e8. Epub 2018 Jun 8 doi: 10.1016/j.jhsa.2018.03.050. PMID: 29891270

Recent clinical studies

Etiology

Open-wedge osteotomy for thumb radial angulation in Apert syndrome using a bone-graft substitute.
Shintani K, Kazuki K, Nakagawa K, Hosomi R, Kitano T
J Pediatr Orthop B 2022 Sep 1;31(5):500-504. Epub 2021 Dec 2 doi: 10.1097/BPB.0000000000000938. PMID: 35438886
Distraction Lengthening of the Apert Thumb.
Upton J, McNamara CT, Ali B, Nuzzi LC, Taghinia AH, Labow BI
Plast Reconstr Surg 2022 Apr 1;149(4):691e-699e. doi: 10.1097/PRS.0000000000008929. PMID: 35157629
Central Coalition Osteotomy of Phalangeal Synostoses in the Management of the Type III Apert Hand.
Theman TA, Upton J, Taghinia AH, Firriolo JM, Nuzzi LC, Labow BI
J Hand Surg Am 2018 Nov;43(11):1042.e1-1042.e8. Epub 2018 Jun 8 doi: 10.1016/j.jhsa.2018.03.050. PMID: 29891270
Application of C-Shaped Osteotomy and Distraction Osteogenesis for Correction of Radial Angulation Deformities of the Hand in Children With Apert Syndrome: Review of 10 Years of Experience.
Vargel I, Calis M, Cavusoglu T, Ekin O, Oznur A
Ann Plast Surg 2015 Nov;75(5):513-7. doi: 10.1097/SAP.0000000000000353. PMID: 25275478
The anatomy and management of the thumb in Apert syndrome.
Fereshetian S, Upton J
Clin Plast Surg 1991 Apr;18(2):365-80. PMID: 2065494

Diagnosis

Triphalangeal thump, thumb duplication, and syndactyly: The first case report in the literature.
Swed S, Nashwan AJ, Saleh HH, Chawa Y, Baria A, Etr A
Medicine (Baltimore) 2022 Oct 21;101(42):e31237. doi: 10.1097/MD.0000000000031237. PMID: 36281136Free PMC Article
Hypothesis: Symbrachydactyly.
Holmes LB, Nasri HZ
Am J Med Genet A 2022 Nov;188(11):3236-3241. Epub 2022 Sep 8 doi: 10.1002/ajmg.a.62941. PMID: 36073773
Craniosynostosis: Acrocephalosyndactyly (Apert Syndrome) Diagnosed in a Newborn.
Stomnaroska O, Danilovski D, Ivanovska S
Pril (Makedon Akad Nauk Umet Odd Med Nauki) 2017 Dec 1;38(3):153-155. doi: 10.2478/prilozi-2018-0016. PMID: 29668474
Apert syndrome - clinical case.
Siminel MA, NeamŢu CO, DiŢescu D, ForŢofoiu MC, Comănescu AC, Novac MB, NeamŢu SD, Gluhovschi A
Rom J Morphol Embryol 2017;58(1):277-280. PMID: 28523332
Are triphalangeal thumb-polysyndactyly syndrome (TPTPS) and tibial hemimelia-polysyndactyly-triphalangeal thumb syndrome (THPTTS) identical? A father with TPTPS and his daughter with THPTTS in a Thai family.
Kantaputra PN, Chalidapong P
Am J Med Genet 2000 Jul 17;93(2):126-31. doi: 10.1002/1096-8628(20000717)93:2<126::aid-ajmg9>3.0.co;2-s. PMID: 10869115

Prognosis

Craniosynostosis: Acrocephalosyndactyly (Apert Syndrome) Diagnosed in a Newborn.
Stomnaroska O, Danilovski D, Ivanovska S
Pril (Makedon Akad Nauk Umet Odd Med Nauki) 2017 Dec 1;38(3):153-155. doi: 10.2478/prilozi-2018-0016. PMID: 29668474
Application of C-Shaped Osteotomy and Distraction Osteogenesis for Correction of Radial Angulation Deformities of the Hand in Children With Apert Syndrome: Review of 10 Years of Experience.
Vargel I, Calis M, Cavusoglu T, Ekin O, Oznur A
Ann Plast Surg 2015 Nov;75(5):513-7. doi: 10.1097/SAP.0000000000000353. PMID: 25275478
On-top plasty using a free metacarpal head graft for lengthening of proximal phalanx in symbrachydactyly--a case report.
Iba K, Wada T, Yamashita T
Hand Surg 2013;18(2):273-5. doi: 10.1142/S0218810413720192. PMID: 24164137
Thumb radial angulation correction without phalangeal osteotomy in Apert's syndrome.
Dao KD, Shin AY, Kelley S, Wood VE
J Hand Surg Am 2002 Jan;27(1):125-32. doi: 10.1053/jhsu.2002.27772. PMID: 11810626
Type 3 Pfeiffer syndrome with normal thumbs.
Kerr NC, Wilroy RS Jr, Kaufman RA
Am J Med Genet 1996 Dec 11;66(2):138-43. doi: 10.1002/(SICI)1096-8628(19961211)66:2<138::AID-AJMG3>3.0.CO;2-N. PMID: 8958319

Clinical prediction guides

Thumb and first webspace reconstruction in nonsyndromic congenital mitten hand with symbrachydactyly.
Shen XF, Yin F, Gasteratos K, Wang J, Chim H, Rui YJ
J Plast Reconstr Aesthet Surg 2022 Jun;75(6):1902-1906. Epub 2021 Dec 6 doi: 10.1016/j.bjps.2021.11.113. PMID: 34972652
Central Coalition Osteotomy of Phalangeal Synostoses in the Management of the Type III Apert Hand.
Theman TA, Upton J, Taghinia AH, Firriolo JM, Nuzzi LC, Labow BI
J Hand Surg Am 2018 Nov;43(11):1042.e1-1042.e8. Epub 2018 Jun 8 doi: 10.1016/j.jhsa.2018.03.050. PMID: 29891270
Application of C-Shaped Osteotomy and Distraction Osteogenesis for Correction of Radial Angulation Deformities of the Hand in Children With Apert Syndrome: Review of 10 Years of Experience.
Vargel I, Calis M, Cavusoglu T, Ekin O, Oznur A
Ann Plast Surg 2015 Nov;75(5):513-7. doi: 10.1097/SAP.0000000000000353. PMID: 25275478
The anatomy and management of the thumb in Apert syndrome.
Fereshetian S, Upton J
Clin Plast Surg 1991 Apr;18(2):365-80. PMID: 2065494
Cleft hand.
Ogino T
Hand Clin 1990 Nov;6(4):661-71. PMID: 2176655

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