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Rhomboid or triangular shaped 5th finger proximal phalanx

MedGen UID:
870078
•Concept ID:
C4024509
•
Anatomical Abnormality
Synonyms: Rhomboid or triangular shaped innermost bone of little finger; Rhomboid or triangular shaped innermost bone of pinkie finger; Rhomboid or triangular shaped innermost bone of pinky finger
 
HPO: HP:0009236

Definition

Rhomboid or triangular shaped 5th (little) finger proximal phalanx. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRhomboid or triangular shaped 5th finger proximal phalanx

Professional guidelines

PubMed

Scapula alata: Diagnosis and treatment by nerve surgery and tendon transfers.
Lafosse T, D'Utruy A, El Hassan B, Grandjean A, Bouyer M, Masmejean E
Hand Surg Rehabil 2022 Feb;41S:S44-S53. Epub 2021 Jul 8 doi: 10.1016/j.hansur.2020.09.016. PMID: 34246815
Genetic and developmental disorders of the oral mucosa: Epidemiology; molecular mechanisms; diagnostic criteria; management.
Pinna R, Cocco F, Campus G, Conti G, Milia E, Sardella A, Cagetti MG
Periodontol 2000 2019 Jun;80(1):12-27. doi: 10.1111/prd.12261. PMID: 31090139
Anatomy, Etiology, and Management of Scapular Winging.
Didesch JT, Tang P
J Hand Surg Am 2019 Apr;44(4):321-330. Epub 2018 Oct 3 doi: 10.1016/j.jhsa.2018.08.008. PMID: 30292717

Recent clinical studies

Etiology

Denture stomatitis-An interdisciplinary clinical review.
McReynolds DE, Moorthy A, Moneley JO, Jabra-Rizk MA, Sultan AS
J Prosthodont 2023 Aug;32(7):560-570. Epub 2023 Apr 18 doi: 10.1111/jopr.13687. PMID: 36988151
Autophagy in age-related macular degeneration.
Kaarniranta K, Blasiak J, Liton P, Boulton M, Klionsky DJ, Sinha D
Autophagy 2023 Feb;19(2):388-400. Epub 2022 May 1 doi: 10.1080/15548627.2022.2069437. PMID: 35468037Free PMC Article
Intramembrane proteases as drug targets.
Verhelst SHL
FEBS J 2017 May;284(10):1489-1502. Epub 2017 Jan 6 doi: 10.1111/febs.13979. PMID: 27889944
Biology of rhomboid proteases in infectious diseases.
Dogga SK, Soldati-Favre D
Semin Cell Dev Biol 2016 Dec;60:38-45. Epub 2016 Aug 24 doi: 10.1016/j.semcdb.2016.08.020. PMID: 27567708
Rhomboids, signalling and cell biology.
Freeman M
Biochem Soc Trans 2016 Jun 15;44(3):945-50. doi: 10.1042/BST20160035. PMID: 27284064Free PMC Article

Diagnosis

Monoclonal Immunoglobulin Crystalline Membranous Nephropathy.
Mignano SE, Pascal V, Odioemene NE, Forehand W, Javaugue V, Said SM, Sethi S, Sirac C, Nasr SH
Am J Kidney Dis 2024 Jul;84(1):120-125. Epub 2024 Jan 23 doi: 10.1053/j.ajkd.2023.11.011. PMID: 38266972
Pilonidal Disease: To Flap or Not to Flap.
Obokhare I, Amajoyi RC
Adv Surg 2023 Sep;57(1):155-169. Epub 2023 May 25 doi: 10.1016/j.yasu.2023.04.011. PMID: 37536851
Autophagy in age-related macular degeneration.
Kaarniranta K, Blasiak J, Liton P, Boulton M, Klionsky DJ, Sinha D
Autophagy 2023 Feb;19(2):388-400. Epub 2022 May 1 doi: 10.1080/15548627.2022.2069437. PMID: 35468037Free PMC Article
Dry Needling-Induced Pneumothorax.
Patel N, Patel M, Poustinchian B
J Am Osteopath Assoc 2019 Jan 1;119(1):59-62. doi: 10.7556/jaoa.2019.009. PMID: 30615043
Pilonidal sinus disease.
de Parades V, Bouchard D, Janier M, Berger A
J Visc Surg 2013 Sep;150(4):237-47. Epub 2013 Aug 1 doi: 10.1016/j.jviscsurg.2013.05.006. PMID: 23911903

Therapy

Congenital iRHOM2 deficiency causes ADAM17 dysfunction and environmentally directed immunodysregulatory disease.
Kubo S, Fritz JM, Raquer-McKay HM, Kataria R, Vujkovic-Cvijin I, Al-Shaibi A, Yao Y, Zheng L, Zou J, Waldman AD, Jing X, Farley TK, Park AY, Oler AJ, Charles AK, Makhlouf M, AbouMoussa EH, Hasnah R, Saraiva LR, Ganesan S, Al-Subaiey AA, Matthews H, Flano E, Lee HH, Freeman AF, Sefer AP, Sayar E, Çakır E, Karakoc-Aydiner E, Baris S, Belkaid Y, Ozen A, Lo B, Lenardo MJ
Nat Immunol 2022 Jan;23(1):75-85. Epub 2021 Dec 22 doi: 10.1038/s41590-021-01093-y. PMID: 34937930Free PMC Article
Dry Needling-Induced Pneumothorax.
Patel N, Patel M, Poustinchian B
J Am Osteopath Assoc 2019 Jan 1;119(1):59-62. doi: 10.7556/jaoa.2019.009. PMID: 30615043
Rhomboid proteases in human disease: Mechanisms and future prospects.
Düsterhöft S, Künzel U, Freeman M
Biochim Biophys Acta Mol Cell Res 2017 Nov;1864(11 Pt B):2200-2209. Epub 2017 Apr 28 doi: 10.1016/j.bbamcr.2017.04.016. PMID: 28460881
Perspectives of drug-based neuroprotection targeting mitochondria.
Procaccio V, Bris C, Chao de la Barca JM, Oca F, Chevrollier A, Amati-Bonneau P, Bonneau D, Reynier P
Rev Neurol (Paris) 2014 May;170(5):390-400. Epub 2014 May 1 doi: 10.1016/j.neurol.2014.03.005. PMID: 24792485
Acrokeratoelastoidosis.
Hu W, Cook TF, Vicki GJ, Glaser DA
Pediatr Dermatol 2002 Jul-Aug;19(4):320-2. doi: 10.1046/j.1525-1470.2002.00091.x. PMID: 12220276

Prognosis

Denture stomatitis-An interdisciplinary clinical review.
McReynolds DE, Moorthy A, Moneley JO, Jabra-Rizk MA, Sultan AS
J Prosthodont 2023 Aug;32(7):560-570. Epub 2023 Apr 18 doi: 10.1111/jopr.13687. PMID: 36988151
RHBDF2 is correlated with immune infiltrates in hepatocellular carcinoma and may have potential as a biomarker.
Gong H, Xie H, Huangfu Z, Zhang S, Tang Y, Xiao M, Li M, Wang Y
FEBS Open Bio 2023 May;13(5):881-897. Epub 2023 Apr 5 doi: 10.1002/2211-5463.13598. PMID: 36943228Free PMC Article
Inactive rhomboid proteins: New mechanisms with implications in health and disease.
Lemberg MK, Adrain C
Semin Cell Dev Biol 2016 Dec;60:29-37. Epub 2016 Jul 1 doi: 10.1016/j.semcdb.2016.06.022. PMID: 27378062
Pilonidal sinus disease.
de Parades V, Bouchard D, Janier M, Berger A
J Visc Surg 2013 Sep;150(4):237-47. Epub 2013 Aug 1 doi: 10.1016/j.jviscsurg.2013.05.006. PMID: 23911903
Acrokeratoelastoidosis.
Hu W, Cook TF, Vicki GJ, Glaser DA
Pediatr Dermatol 2002 Jul-Aug;19(4):320-2. doi: 10.1046/j.1525-1470.2002.00091.x. PMID: 12220276

Clinical prediction guides

Japanese encephalitis virus hijacks ER-associated degradation regulators for its replication.
Sarkar R, Chhabra S, Tanwar M, Agarwal N, Kalia M
J Gen Virol 2024 May;105(5) doi: 10.1099/jgv.0.001995. PMID: 38787366
Mechanistic insight on the role of iRhom2-TNF-α-BAFF signaling pathway in various autoimmune disorders.
Dwivedi SD, Shukla R, Yadav K, Rathor LS, Singh D, Singh MR
Adv Biol Regul 2024 May;92:101011. Epub 2023 Dec 14 doi: 10.1016/j.jbior.2023.101011. PMID: 38151421
Congenital iRHOM2 deficiency causes ADAM17 dysfunction and environmentally directed immunodysregulatory disease.
Kubo S, Fritz JM, Raquer-McKay HM, Kataria R, Vujkovic-Cvijin I, Al-Shaibi A, Yao Y, Zheng L, Zou J, Waldman AD, Jing X, Farley TK, Park AY, Oler AJ, Charles AK, Makhlouf M, AbouMoussa EH, Hasnah R, Saraiva LR, Ganesan S, Al-Subaiey AA, Matthews H, Flano E, Lee HH, Freeman AF, Sefer AP, Sayar E, Çakır E, Karakoc-Aydiner E, Baris S, Belkaid Y, Ozen A, Lo B, Lenardo MJ
Nat Immunol 2022 Jan;23(1):75-85. Epub 2021 Dec 22 doi: 10.1038/s41590-021-01093-y. PMID: 34937930Free PMC Article
iRhom2 inhibits bile duct obstruction-induced liver fibrosis.
Sundaram B, Behnke K, Belancic A, Al-Salihi MA, Thabet Y, Polz R, Pellegrino R, Zhuang Y, Shinde PV, Xu HC, Vasilevska J, Longerich T, Herebian D, Mayatepek E, Bock HH, May P, Kordes C, Aghaeepour N, Mak TW, Keitel V, Häussinger D, Scheller J, Pandyra AA, Lang KS, Lang PA
Sci Signal 2019 Oct 29;12(605) doi: 10.1126/scisignal.aax1194. PMID: 31662486
Inactive rhomboid proteins: New mechanisms with implications in health and disease.
Lemberg MK, Adrain C
Semin Cell Dev Biol 2016 Dec;60:29-37. Epub 2016 Jul 1 doi: 10.1016/j.semcdb.2016.06.022. PMID: 27378062

Recent systematic reviews

The Efficacy and Safety of the Rhomboid Intercostal Block for Postoperative Analgesia in Chest Surgery and Breast Surgery: A Systemic Review and Meta-Analysis.
Shen QH, Lv YZ, Shi YF, Lai L, Chen YJ, Zhou QH
Pain Physician 2024 Sep;27(7):375-385. PMID: 39353106
Ischemic pressure vs. post-isometric relaxation for treatment of rhomboid latent myofascial trigger point: a systemic review.
Albaker AB
Eur Rev Med Pharmacol Sci 2023 Jun;27(11):5031-5038. doi: 10.26355/eurrev_202306_32620. PMID: 37318477
Anoplasty for anatomical anal stenosis: systematic review of complications and recurrences.
Gallo G, Picciariello A, Di Tanna GL, Pelizzo P, Altomare DF, Trompetto M, Santoro GA, Roviello F, Felice C, Grossi U
Colorectal Dis 2022 Dec;24(12):1462-1471. Epub 2022 Jul 31 doi: 10.1111/codi.16248. PMID: 35792887Free PMC Article
Use of Local Flaps for Soft-Tissue Closure in Diabetic Foot Wounds: A Systematic Review.
Ramanujam CL, Zgonis T
Foot Ankle Spec 2019 Jun;12(3):286-293. Epub 2018 Oct 17 doi: 10.1177/1938640018803745. PMID: 30328715
Urban legends series: oral candidosis.
Manfredi M, Polonelli L, Aguirre-Urizar JM, Carrozzo M, McCullough MJ
Oral Dis 2013 Apr;19(3):245-61. Epub 2012 Sep 24 doi: 10.1111/odi.12013. PMID: 22998462

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