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Visnas

MedGen UID:
87015
•Concept ID:
C0080323
•
Disease or Syndrome
Synonyms: Encephalomyelitides, Ovine; Encephalomyelitis, Ovine; Ovine Encephalomyelitides; Ovine Encephalomyelitis; Visna

Definition

Demyelinating leukoencephalomyelitis of sheep caused by the VISNA-MAEDI VIRUS. It is similar to but not the same as SCRAPIE. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVisnas

Recent clinical studies

Etiology

Domain Organization of Lentiviral and Betaretroviral Surface Envelope Glycoproteins Modeled with AlphaFold.
Hötzel I
J Virol 2022 Jan 26;96(2):e0134821. Epub 2021 Oct 27 doi: 10.1128/JVI.01348-21. PMID: 34705555Free PMC Article
Influence of proinflammatory cytokines and chemokines on the neuropathogenesis of oncornavirus and immunosuppressive lentivirus infections.
Peterson KE, Chesebro B
Curr Top Microbiol Immunol 2006;303:67-95. doi: 10.1007/978-3-540-33397-5_4. PMID: 16570857
HIV-1-associated central nervous system dysfunction.
Krebs FC, Ross H, McAllister J, Wigdahl B
Adv Pharmacol 2000;49:315-85. doi: 10.1016/s1054-3589(00)49031-9. PMID: 11013768
Diffuse infiltrative lymphocytosis syndrome in children and adults infected with HIV-1: a model of rheumatic illness caused by acquired viral infection.
Itescu S
Am J Reprod Immunol 1992 Oct-Dec;28(3-4):247-50. doi: 10.1111/j.1600-0897.1992.tb00806.x. PMID: 1285893
Human and experimental spongiform encephalopathies: recent progress in pathogenesis.
Dal Canto MC
Ital J Neurol Sci 1991 Apr;12(2):147-53. doi: 10.1007/BF02337026. PMID: 1676992

Diagnosis

Efficacy of adenoviral TNF alpha antisense is enhanced by a macrophage specific promoter.
Sidiropoulos P, Liu H, Mungre S, Anderson L, Thimmapaya B, Pope RM
Gene Ther 2001 Feb;8(3):223-31. doi: 10.1038/sj.gt.3301368. PMID: 11313794
Retroviruses and systemic lupus erythematosus.
Herrmann M, Hagenhofer M, Kalden JR
Immunol Rev 1996 Aug;152:145-56. doi: 10.1111/j.1600-065x.1996.tb00914.x. PMID: 8930671
Diffuse infiltrative lymphocytosis syndrome in children and adults infected with HIV-1: a model of rheumatic illness caused by acquired viral infection.
Itescu S
Am J Reprod Immunol 1992 Oct-Dec;28(3-4):247-50. doi: 10.1111/j.1600-0897.1992.tb00806.x. PMID: 1285893
Retrovirus-associated myelopathies.
Román GC
Arch Neurol 1987 Jun;44(6):659-63. doi: 10.1001/archneur.1987.00520180073022. PMID: 2883964
Lymphadenopathy-associated virus: from molecular biology to pathogenicity.
Montagnier L
Ann Intern Med 1985 Nov;103(5):689-93. doi: 10.7326/0003-4819-103-5-689. PMID: 2996400

Therapy

Mapping and characterization of visna/maedi virus cytotoxic T-lymphocyte epitopes.
Wu C, Barbezange C, McConnell I, Blacklaws BA
J Gen Virol 2008 Oct;89(Pt 10):2586-2596. doi: 10.1099/vir.0.2008/002634-0. PMID: 18796728
Current development of lentiviral-mediated gene transfer.
Romano G
Drug News Perspect 2005 Mar;18(2):128-34. doi: 10.1358/dnp.2005.18.2.886481. PMID: 15883621
Treatment of deep cartilage defects of the knee using autologous chondrograft transplantation and by abrasive techniques--a randomized controlled study.
Visna P, Pasa L, Cizmár I, Hart R, Hoch J
Acta Chir Belg 2004 Nov-Dec;104(6):709-14. doi: 10.1080/00015458.2004.11679648. PMID: 15663280
The origin of HIV-1, the AIDS virus.
Siefkes D
Med Hypotheses 1993 Oct;41(4):289-99. doi: 10.1016/0306-9877(93)90069-3. PMID: 8289690Free PMC Article
A review of the sheep-multiple sclerosis connection.
Murrell TG, O'Donoghue PJ, Ellis T
Med Hypotheses 1986 Jan;19(1):27-39. doi: 10.1016/0306-9877(86)90134-9. PMID: 2871478

Prognosis

Domain Organization of Lentiviral and Betaretroviral Surface Envelope Glycoproteins Modeled with AlphaFold.
Hötzel I
J Virol 2022 Jan 26;96(2):e0134821. Epub 2021 Oct 27 doi: 10.1128/JVI.01348-21. PMID: 34705555Free PMC Article
Maedi-visna virus and its relationship to human immunodeficiency virus.
Thormar H
AIDS Rev 2005 Oct-Dec;7(4):233-45. PMID: 16425963
HIV-1-associated central nervous system dysfunction.
Krebs FC, Ross H, McAllister J, Wigdahl B
Adv Pharmacol 2000;49:315-85. doi: 10.1016/s1054-3589(00)49031-9. PMID: 11013768
Human and experimental spongiform encephalopathies: recent progress in pathogenesis.
Dal Canto MC
Ital J Neurol Sci 1991 Apr;12(2):147-53. doi: 10.1007/BF02337026. PMID: 1676992
The neurobiology of human immunodeficiency virus infections.
Johnson RT, McArthur JC, Narayan O
FASEB J 1988 Nov;2(14):2970-81. doi: 10.1096/fasebj.2.14.2846395. PMID: 2846395

Clinical prediction guides

Maedi-visna virus and its relationship to human immunodeficiency virus.
Thormar H
AIDS Rev 2005 Oct-Dec;7(4):233-45. PMID: 16425963
HIV-1-associated central nervous system dysfunction.
Krebs FC, Ross H, McAllister J, Wigdahl B
Adv Pharmacol 2000;49:315-85. doi: 10.1016/s1054-3589(00)49031-9. PMID: 11013768
Neuropathologic aspects of lentiviral infections.
Georgsson G
Ann N Y Acad Sci 1994 Jun 6;724:50-67. doi: 10.1111/j.1749-6632.1994.tb38895.x. PMID: 8030977
Human and ovine lentiviral infections compared.
Pétursson G, Andrésdóttir V, Andrésson O, Torsteinsdóttir S, Georgsson G, Pálsson PA
Comp Immunol Microbiol Infect Dis 1991;14(4):277-87. doi: 10.1016/0147-9571(91)90133-x. PMID: 1684142
Notes on the pathogenesis of subacute sclerosing panencephalitis.
Poser CM
J Neurol Sci 1990 Feb;95(2):219-24. doi: 10.1016/0022-510x(90)90244-h. PMID: 2182785

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