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Renal hypophosphatemia

MedGen UID:
870197
Concept ID:
C4024631
Disease or Syndrome
HPO: HP:0008732

Definition

Renal hypophosphatemia is defined as reduced serum phosphate (e.g., below 0.70 mmol/l) and an inappropriately high renal phosphate excretion. [from HPO]

Term Hierarchy

Professional guidelines

PubMed

Haffner D, Leifheit-Nestler M, Grund A, Schnabel D
Pediatr Nephrol 2022 Oct;37(10):2289-2302. Epub 2022 Mar 29 doi: 10.1007/s00467-022-05505-5. PMID: 35352187Free PMC Article
Laurent MR, De Schepper J, Trouet D, Godefroid N, Boros E, Heinrichs C, Bravenboer B, Velkeniers B, Lammens J, Harvengt P, Cavalier E, Kaux JF, Lombet J, De Waele K, Verroken C, van Hoeck K, Mortier GR, Levtchenko E, Vande Walle J
Front Endocrinol (Lausanne) 2021;12:641543. Epub 2021 Mar 19 doi: 10.3389/fendo.2021.641543. PMID: 33815294Free PMC Article
Haffner D, Emma F, Eastwood DM, Duplan MB, Bacchetta J, Schnabel D, Wicart P, Bockenhauer D, Santos F, Levtchenko E, Harvengt P, Kirchhoff M, Di Rocco F, Chaussain C, Brandi ML, Savendahl L, Briot K, Kamenicky P, Rejnmark L, Linglart A
Nat Rev Nephrol 2019 Jul;15(7):435-455. doi: 10.1038/s41581-019-0152-5. PMID: 31068690Free PMC Article

Recent clinical studies

Etiology

García-Castaño A, Madariaga L, Gómez-Conde S, González P, Grau G, Rica I, de Nanclares GP, De la Hoz AB, Aguayo A, Martínez R, Urrutia I, Gaztambide S; Calcium Phosphorus Metabolism Molecular Biology Group, Castaño L
Front Endocrinol (Lausanne) 2024;15:1297614. Epub 2024 Mar 22 doi: 10.3389/fendo.2024.1297614. PMID: 38586466Free PMC Article
Kim KJ, Song JE, Kim JH, Hong N, Kim SG, Lee J, Rhee Y
Front Endocrinol (Lausanne) 2023;14:1229750. Epub 2023 Aug 10 doi: 10.3389/fendo.2023.1229750. PMID: 37635983Free PMC Article
García-Nieto VM, González-Rodríguez JD, Cabrera-Sevilla JE, Martín-Fernández de Basoa MC, Luis-Yanes MI
Pediatr Nephrol 2023 Nov;38(11):3845-3848. Epub 2023 Apr 13 doi: 10.1007/s00467-023-05941-x. PMID: 37052691
Bech AP, Hoorn EJ, Zietse R, Wetzels JFM, Nijenhuis T
BMC Nephrol 2018 Sep 4;19(1):220. doi: 10.1186/s12882-018-1017-z. PMID: 30180816Free PMC Article
Harrrison HE, Harrison HC
J Pediatr 1975 Dec;87(6 Pt 2):1144-51. doi: 10.1016/s0022-3476(75)80129-6. PMID: 1102648

Diagnosis

García-Castaño A, Madariaga L, Gómez-Conde S, González P, Grau G, Rica I, de Nanclares GP, De la Hoz AB, Aguayo A, Martínez R, Urrutia I, Gaztambide S; Calcium Phosphorus Metabolism Molecular Biology Group, Castaño L
Front Endocrinol (Lausanne) 2024;15:1297614. Epub 2024 Mar 22 doi: 10.3389/fendo.2024.1297614. PMID: 38586466Free PMC Article
García-Nieto VM, González-Rodríguez JD, Cabrera-Sevilla JE, Martín-Fernández de Basoa MC, Luis-Yanes MI
Pediatr Nephrol 2023 Nov;38(11):3845-3848. Epub 2023 Apr 13 doi: 10.1007/s00467-023-05941-x. PMID: 37052691
Bech AP, Hoorn EJ, Zietse R, Wetzels JFM, Nijenhuis T
BMC Nephrol 2018 Sep 4;19(1):220. doi: 10.1186/s12882-018-1017-z. PMID: 30180816Free PMC Article
Tasic V, Gucev Z
Pediatr Endocrinol Rev 2015 Sep;13(1):468-76. PMID: 26540764
Imel EA, Econs MJ
J Clin Endocrinol Metab 2012 Mar;97(3):696-706. doi: 10.1210/jc.2011-1319. PMID: 22392950Free PMC Article

Therapy

Bech AP, Hoorn EJ, Zietse R, Wetzels JFM, Nijenhuis T
BMC Nephrol 2018 Sep 4;19(1):220. doi: 10.1186/s12882-018-1017-z. PMID: 30180816Free PMC Article
Bonjoch A, Puig J, Pérez-Alvarez N, Juega J, Echeverría P, Clotet B, Romero R, Bonet J, Negredo E
Medicine (Baltimore) 2016 Aug;95(32):e4507. doi: 10.1097/MD.0000000000004507. PMID: 27512868Free PMC Article
Imel EA, Econs MJ
J Clin Endocrinol Metab 2012 Mar;97(3):696-706. doi: 10.1210/jc.2011-1319. PMID: 22392950Free PMC Article
Decaux G
Nephron 1988;48(1):40-2. doi: 10.1159/000184866. PMID: 3277077
Harrrison HE, Harrison HC
J Pediatr 1975 Dec;87(6 Pt 2):1144-51. doi: 10.1016/s0022-3476(75)80129-6. PMID: 1102648

Prognosis

Betton M, Blanchard A, Houillier P, Vargas-Poussou R, Hureaux M
J Nephrol 2024 Sep;37(7):1973-1983. Epub 2024 Sep 11 doi: 10.1007/s40620-024-02054-y. PMID: 39261397
Kim KJ, Song JE, Kim JH, Hong N, Kim SG, Lee J, Rhee Y
Front Endocrinol (Lausanne) 2023;14:1229750. Epub 2023 Aug 10 doi: 10.3389/fendo.2023.1229750. PMID: 37635983Free PMC Article

Clinical prediction guides

Michon-Colin A, Bouderlique E, Prié D, Maruani G, Nevoux J, Briot K, Courbebaisse M
Calcif Tissue Int 2024 Mar;114(3):310-314. Epub 2024 Jan 9 doi: 10.1007/s00223-023-01169-x. PMID: 38195892
Kim KJ, Song JE, Kim JH, Hong N, Kim SG, Lee J, Rhee Y
Front Endocrinol (Lausanne) 2023;14:1229750. Epub 2023 Aug 10 doi: 10.3389/fendo.2023.1229750. PMID: 37635983Free PMC Article
García-Nieto VM, González-Rodríguez JD, Cabrera-Sevilla JE, Martín-Fernández de Basoa MC, Luis-Yanes MI
Pediatr Nephrol 2023 Nov;38(11):3845-3848. Epub 2023 Apr 13 doi: 10.1007/s00467-023-05941-x. PMID: 37052691
Giralt M, Chocron S, Ferrer R, Ariceta G
Pediatr Nephrol 2021 Apr;36(4):1025-1028. Epub 2021 Jan 25 doi: 10.1007/s00467-020-04906-8. PMID: 33492457
Bech AP, Hoorn EJ, Zietse R, Wetzels JFM, Nijenhuis T
BMC Nephrol 2018 Sep 4;19(1):220. doi: 10.1186/s12882-018-1017-z. PMID: 30180816Free PMC Article

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