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Monocular horizontal nystagmus

MedGen UID:
870363
•Concept ID:
C4024807
•
Congenital Abnormality
HPO: HP:0007747

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMonocular horizontal nystagmus

Conditions with this feature

Chorea, remitting, with nystagmus and cataract
MedGen UID:
330463
•Concept ID:
C1832422
•
Disease or Syndrome
See: Condition Record
Chorea, remitting, with nystagmus and cataract

Professional guidelines

PubMed

Fixation instability in amblyopia: Oculomotor disease biomarkers predictive of treatment effectiveness.
Scaramuzzi M, Murray J, Otero-Millan J, Nucci P, Shaikh AG, Ghasia FF
Prog Brain Res 2019;249:235-248. Epub 2019 Jun 20 doi: 10.1016/bs.pbr.2019.04.024. PMID: 31325983Free PMC Article
Dissociated horizontal deviation: clinical spectrum, pathogenesis, evolutionary underpinnings, diagnosis, treatment, and potential role in the development of infantile esotropia (an American Ophthalmological Society thesis).
Brodsky MC
Trans Am Ophthalmol Soc 2007;105:272-93. PMID: 18427617Free PMC Article
The effect of prolonged monocular occlusion on latent nystagmus in the treatment of amblyopia.
Simonsz HJ, Kommerell G
Bull Soc Belge Ophtalmol 1989;232:7-12. PMID: 2490389

Recent clinical studies

Etiology

Nystagmus associated with macular dysplasia.
Wang FB
Strabismus 2020 Mar;28(1):17-19. Epub 2019 Sep 30 doi: 10.1080/09273972.2019.1668028. PMID: 31566469
Infantile Nystagmus and Abnormalities of Conjugate Eye Movements in Down Syndrome.
Weiss AH, Kelly JP, Phillips JO
Invest Ophthalmol Vis Sci 2016 Mar;57(3):1301-9. doi: 10.1167/iovs.15-18532. PMID: 26998716
Causes and characteristics of horizontal positional nystagmus.
Lechner C, Taylor RL, Todd C, Macdougall H, Yavor R, Halmagyi GM, Welgampola MS
J Neurol 2014 May;261(5):1009-17. Epub 2014 Mar 28 doi: 10.1007/s00415-013-7223-5. PMID: 24676938
Monocular and binocular development in children with albinism, infantile nystagmus syndrome, and normal vision.
Huurneman B, Boonstra FN
Strabismus 2013 Dec;21(4):216-24. Epub 2013 Nov 6 doi: 10.3109/09273972.2013.833954. PMID: 24195763
Vision in albinism.
Summers CG
Trans Am Ophthalmol Soc 1996;94:1095-155. PMID: 8981720Free PMC Article

Diagnosis

Monocular and Binocular Temporal Visual Perception of Infantile Nystagmus.
Moshkovitz A, Lev M, Polat U
Sci Rep 2020 Mar 18;10(1):4946. doi: 10.1038/s41598-020-61914-2. PMID: 32188906Free PMC Article
Nystagmus associated with macular dysplasia.
Wang FB
Strabismus 2020 Mar;28(1):17-19. Epub 2019 Sep 30 doi: 10.1080/09273972.2019.1668028. PMID: 31566469
Abnormal fixational eye movements in strabismus.
Ghasia FF, Otero-Millan J, Shaikh AG
Br J Ophthalmol 2018 Feb;102(2):253-259. Epub 2017 Jul 11 doi: 10.1136/bjophthalmol-2017-310346. PMID: 28698242
Causes and characteristics of horizontal positional nystagmus.
Lechner C, Taylor RL, Todd C, Macdougall H, Yavor R, Halmagyi GM, Welgampola MS
J Neurol 2014 May;261(5):1009-17. Epub 2014 Mar 28 doi: 10.1007/s00415-013-7223-5. PMID: 24676938
See-saw nystagmus and congenital nystagmus identified in the non-decussating retinal-fugal fiber syndrome.
Apkarian P, Bour LJ
Strabismus 2001 Sep;9(3):143-63. doi: 10.1076/stra.9.3.143.6761. PMID: 11704879

Therapy

Gabapentin and Memantine for Treatment of Acquired Pendular Nystagmus: Effects on Visual Outcomes.
Nerrant E, Abouaf L, Pollet-Villard F, Vie AL, Vukusic S, Berthiller J, Colombet B, Vighetto A, Tilikete C
J Neuroophthalmol 2020 Jun;40(2):198-206. doi: 10.1097/WNO.0000000000000807. PMID: 31169568
Evaluation of eye-related parameters and adverse events of rigid gas permeable contact lens and spectacles correction in infants with monocular aphakia after congenital cataract surgery: a retrospective clinical study.
Chen J, Sun P, Wei Y, Kang X
BMC Ophthalmol 2019 Mar 20;19(1):81. doi: 10.1186/s12886-019-1088-z. PMID: 30894149Free PMC Article
The effect of horizontal rectus muscle surgery on clinical and eye movement recording indices in infantile nystagmus syndrome.
Bagheri A, Aletaha M, Abrishami M
Strabismus 2010 Jun;18(2):58-64. doi: 10.3109/09273971003758404. PMID: 20521880
Monocular horizontal OKN in observers with early- and late-onset strabismus.
Steeves JK, Reed MJ, Steinbach MJ, Kraft SP
Behav Brain Res 1999 Sep;103(2):135-43. doi: 10.1016/s0166-4328(99)00032-7. PMID: 10513582
Visual pathway abnormalities in albinism and infantile nystagmus: VECPs and stereoacuity measurements.
Guo SQ, Reinecke RD, Fendick M, Calhoun JH
J Pediatr Ophthalmol Strabismus 1989 Mar-Apr;26(2):97-104. doi: 10.3928/0191-3913-19890301-15. PMID: 2709284

Prognosis

Nystagmus associated with macular dysplasia.
Wang FB
Strabismus 2020 Mar;28(1):17-19. Epub 2019 Sep 30 doi: 10.1080/09273972.2019.1668028. PMID: 31566469
Fixation instability in amblyopia: Oculomotor disease biomarkers predictive of treatment effectiveness.
Scaramuzzi M, Murray J, Otero-Millan J, Nucci P, Shaikh AG, Ghasia FF
Prog Brain Res 2019;249:235-248. Epub 2019 Jun 20 doi: 10.1016/bs.pbr.2019.04.024. PMID: 31325983Free PMC Article
Acquired nystagmus as the initial presenting sign of chiasmal glioma in young children.
Toledano H, Muhsinoglu O, Luckman J, Goldenberg-Cohen N, Michowiz S
Eur J Paediatr Neurol 2015 Nov;19(6):694-700. Epub 2015 Jul 9 doi: 10.1016/j.ejpn.2015.06.007. PMID: 26190013
Causes and characteristics of horizontal positional nystagmus.
Lechner C, Taylor RL, Todd C, Macdougall H, Yavor R, Halmagyi GM, Welgampola MS
J Neurol 2014 May;261(5):1009-17. Epub 2014 Mar 28 doi: 10.1007/s00415-013-7223-5. PMID: 24676938
Monocular and binocular development in children with albinism, infantile nystagmus syndrome, and normal vision.
Huurneman B, Boonstra FN
Strabismus 2013 Dec;21(4):216-24. Epub 2013 Nov 6 doi: 10.3109/09273972.2013.833954. PMID: 24195763

Clinical prediction guides

Effect of Viewing Conditions on Fixation Eye Movements and Eye Alignment in Amblyopia.
Murray J, Gupta P, Dulaney C, Garg K, Shaikh AG, Ghasia FF
Invest Ophthalmol Vis Sci 2022 Feb 1;63(2):33. doi: 10.1167/iovs.63.2.33. PMID: 35212720Free PMC Article
Fixation instability in amblyopia: Oculomotor disease biomarkers predictive of treatment effectiveness.
Scaramuzzi M, Murray J, Otero-Millan J, Nucci P, Shaikh AG, Ghasia FF
Prog Brain Res 2019;249:235-248. Epub 2019 Jun 20 doi: 10.1016/bs.pbr.2019.04.024. PMID: 31325983Free PMC Article
Causes and characteristics of horizontal positional nystagmus.
Lechner C, Taylor RL, Todd C, Macdougall H, Yavor R, Halmagyi GM, Welgampola MS
J Neurol 2014 May;261(5):1009-17. Epub 2014 Mar 28 doi: 10.1007/s00415-013-7223-5. PMID: 24676938
Monocular and binocular development in children with albinism, infantile nystagmus syndrome, and normal vision.
Huurneman B, Boonstra FN
Strabismus 2013 Dec;21(4):216-24. Epub 2013 Nov 6 doi: 10.3109/09273972.2013.833954. PMID: 24195763
Disturbances of small-field horizontal and vertical optokinetic nystagmus in amblyopia.
Schor CM, Levi DM
Invest Ophthalmol Vis Sci 1980 Jun;19(6):668-83. PMID: 7380625

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