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Generalized seborrheic dermatitis

MedGen UID:
870399
Concept ID:
C4024844
Disease or Syndrome
Synonyms: Generalised seborrheic dermatitis; Generalised seborrheic eczema; Generalized seborrheic eczema
SNOMED CT: Generalized seborrheic dermatitis (1251359008)
 
HPO: HP:0007569

Definition

Seborrheic dermatitis that is not localized to any one particular region. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGeneralized seborrheic dermatitis

Conditions with this feature

Complement component 5 deficiency
MedGen UID:
91003
Concept ID:
C0343047
Disease or Syndrome
A rare genetic disorder with an autosomal recessive pattern of inheritance. It is caused by the ineffective or decreased biosynthesis of the fifth complement component, C5. C5 deficiency may also be acquired acutely post-infection. If C5 is adequately synthesized, its rapid depletion may result in a functional deficiency. Clinical signs of the inherited deficiency present within the second decade of life and are consistent with the signs of recurrent systemic infection. Deficiency of serum C5 and its major cleavage product, C5b, a component of the membrane attack complex, increases susceptibility to Neisserial infections.

Professional guidelines

PubMed

Tan N, Vary JC Jr, O'Connor KM
Med Clin North Am 2024 Sep;108(5):795-827. Epub 2024 Jun 12 doi: 10.1016/j.mcna.2024.02.002. PMID: 39084835
Vano-Galvan S, Reygagne P, Melo DF, Barbosa V, Wu WY, Moneib H, Piraccini BM
Eur J Dermatol 2024 Jun 1;34(S1):4-16. doi: 10.1684/ejd.2024.4703. PMID: 38919137
Villalon-Gomez JM
Am Fam Physician 2018 Jan 1;97(1):38-44. PMID: 29365241

Recent clinical studies

Diagnosis

Kim HJ, Lim YS, Choi HY, Myung KB
Cutis 2001 Jan;67(1):52-4. PMID: 11204605

Prognosis

Kim HJ, Lim YS, Choi HY, Myung KB
Cutis 2001 Jan;67(1):52-4. PMID: 11204605

Supplemental Content

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