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Cerebellar medulloblastoma

MedGen UID:
870487
•Concept ID:
C4024934
•
Neoplastic Process
HPO: HP:0007129

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Cerebellar medulloblastoma

Conditions with this feature

Blue rubber bleb nevus
MedGen UID:
83401
•Concept ID:
C0346072
•
Congenital Abnormality
A rare vascular malformation disorder with cutaneous and visceral lesions frequently associated with serious, potentially fatal bleeding and anemia.
See: Condition Record
Blue rubber bleb nevus

Professional guidelines

PubMed

Medulloblastoma/primitive neuroectodermal tumor in adults: prognostic factors and treatment results: a single-center experience from Turkey.
Ertas G, Ucer AR, Altundag MB, Durmus S, Calikoglu T, Ozbagi K, Abanuz H, Altundag K, Demirkasimoglu A
Med Oncol 2008;25(1):69-72. Epub 2007 Jul 20 doi: 10.1007/s12032-007-0044-6. PMID: 18188718
Treatment results for 149 medulloblastoma patients from one institution.
Khafaga Y, Kandil AE, Jamshed A, Hassounah M, DeVol E, Gray AJ
Int J Radiat Oncol Biol Phys 1996 Jun 1;35(3):501-6. doi: 10.1016/s0360-3016(96)80012-5. PMID: 8655373
Chemotherapy as an adjunct in the initial management of cerebellar medulloblastomas. A preliminary report.
Venes JL, McIntosh S, O'Brien RT, Schwartz AD
J Neurosurg 1979 Jun;50(6):721-4. doi: 10.3171/jns.1979.50.6.0721. PMID: 438873

Recent clinical studies

Etiology

The effectiveness of diffusion kurtosis imaging metrics for distinguishing between brainstem glioma and cerebellar medulloblastoma.
Minh Duc N
Clin Ter 2024 Jan-Feb;175(1):20-25. doi: 10.7417/CT.2024.5029. PMID: 38358473
The role of diffusion tensor imaging metrics in the discrimination between cerebellar medulloblastoma and brainstem glioma.
Duc NM
Pediatr Blood Cancer 2020 Sep;67(9):e28468. Epub 2020 Jun 26 doi: 10.1002/pbc.28468. PMID: 32588986
Anatomo-functional study of the cerebellum in working memory in children treated for medulloblastoma.
Hoang DH, Pagnier A, Cousin E, Guichardet K, Schiff I, Icher C, Dilharreguy B, Grill J, Frappaz D, Berger C, Schneider F, Dubois-Teklali F, Krainik A
J Neuroradiol 2019 May;46(3):207-213. Epub 2019 Feb 5 doi: 10.1016/j.neurad.2019.01.093. PMID: 30731145
Cancer stem cells in the mammalian central nervous system.
Pilkington GJ
Cell Prolif 2005 Dec;38(6):423-33. doi: 10.1111/j.1365-2184.2005.00358.x. PMID: 16300654Free PMC Article
Prognostic factors in medulloblastoma.
Chin HW, Maruyama Y
Am J Clin Oncol 1982 Aug;5(4):359-69. doi: 10.1097/00000421-198208000-00004. PMID: 6810689

Diagnosis

The effectiveness of diffusion kurtosis imaging metrics for distinguishing between brainstem glioma and cerebellar medulloblastoma.
Minh Duc N
Clin Ter 2024 Jan-Feb;175(1):20-25. doi: 10.7417/CT.2024.5029. PMID: 38358473
The role of diffusion tensor imaging metrics in the discrimination between cerebellar medulloblastoma and brainstem glioma.
Duc NM
Pediatr Blood Cancer 2020 Sep;67(9):e28468. Epub 2020 Jun 26 doi: 10.1002/pbc.28468. PMID: 32588986
Neurocognitive dysfunction in adult cerebellar medulloblastoma.
Harrison RA, Kesler SR, Johnson JM, Penas-Prado M, Sullaway CM, Wefel JS
Psychooncology 2019 Jan;28(1):131-138. Epub 2018 Nov 5 doi: 10.1002/pon.4920. PMID: 30315720
Medulloblastoma in Older Adults: A Case Report and Literature Review.
Murase M, Saito K, Abiko T, Yoshida K, Tomita H
World Neurosurg 2018 Sep;117:25-31. Epub 2018 Jun 5 doi: 10.1016/j.wneu.2018.05.216. PMID: 29883827
CT and MR imaging findings in adults with cerebellar medulloblastoma: comparison with findings in children.
Bourgouin PM, Tampieri D, Grahovac SZ, Léger C, Del Carpio R, Melançon D
AJR Am J Roentgenol 1992 Sep;159(3):609-12. doi: 10.2214/ajr.159.3.1503035. PMID: 1503035

Therapy

The role of diffusion tensor imaging metrics in the discrimination between cerebellar medulloblastoma and brainstem glioma.
Duc NM
Pediatr Blood Cancer 2020 Sep;67(9):e28468. Epub 2020 Jun 26 doi: 10.1002/pbc.28468. PMID: 32588986
Neurocognitive dysfunction in adult cerebellar medulloblastoma.
Harrison RA, Kesler SR, Johnson JM, Penas-Prado M, Sullaway CM, Wefel JS
Psychooncology 2019 Jan;28(1):131-138. Epub 2018 Nov 5 doi: 10.1002/pon.4920. PMID: 30315720
M4 protocol for cerebellar medulloblastoma: supratentorial radiotherapy may not be avoided.
Bouffet E, Bernard JL, Frappaz D, Gentet JC, Roche H, Tron P, Carrie C, Raybaud C, Joannard A, Lapras C
Int J Radiat Oncol Biol Phys 1992;24(1):79-85. doi: 10.1016/0360-3016(92)91025-i. PMID: 1512166
The change in patterns of relapse in medulloblastoma.
Tarbell NJ, Loeffler JS, Silver B, Lynch E, Lavally BL, Kupsky WJ, Scott RM, Sallan SE
Cancer 1991 Oct 1;68(7):1600-4. doi: 10.1002/1097-0142(19911001)68:7<1600::aid-cncr2820680722>3.0.co;2-v. PMID: 1893359
Adjuvant chemotherapy for medulloblastoma.
McIntosh S, Chen M, Sartain PA, Duncan C, Fishburn R, Klatskin EH, Schwartz AD, Venes JL
Cancer 1985 Sep 15;56(6):1316-9. doi: 10.1002/1097-0142(19850915)56:6<1316::aid-cncr2820560616>3.0.co;2-d. PMID: 4027871

Prognosis

Subfrontal recurrence after cerebellar medulloblastoma resection without local relapse: case-based update.
Yue H, Ling W, Yibo O, Sheng W, Sicheng T, Jincao C, Dongsheng G
Childs Nerv Syst 2018 Sep;34(9):1619-1626. Epub 2018 Jun 23 doi: 10.1007/s00381-018-3869-8. PMID: 29934705
Genetic and expression profiles of cerebellar liponeurocytomas.
Horstmann S, Perry A, Reifenberger G, Giangaspero F, Huang H, Hara A, Masuoka J, Rainov NG, Bergmann M, Heppner FL, Brandner S, Chimelli L, Montagna N, Jackson T, Davis DG, Markesbery WR, Ellison DW, Weller RO, Taddei GL, Conti R, Del Bigio MR, González-Cámpora R, Radhakrishnan VV, Söylemezoglu F, Uro-Coste E, Qian J, Kleihues P, Ohgaki H
Brain Pathol 2004 Jul;14(3):281-9. doi: 10.1111/j.1750-3639.2004.tb00065.x. PMID: 15446583Free PMC Article
Incidence and trends in pediatric malignancies medulloblastoma/primitive neuroectodermal tumor: a SEER update. Surveillance Epidemiology and End Results.
McNeil DE, Coté TR, Clegg L, Rorke LB
Med Pediatr Oncol 2002 Sep;39(3):190-4. doi: 10.1002/mpo.10121. PMID: 12210449
Embryonal central neuroepithelial tumors and their differentiating potential. A cytogenetic view of a complex neuro-oncological problem.
Rubinstein LJ
J Neurosurg 1985 Jun;62(6):795-805. doi: 10.3171/jns.1985.62.6.0795. PMID: 2987439
Prognostic factors in medulloblastoma.
Chin HW, Maruyama Y
Am J Clin Oncol 1982 Aug;5(4):359-69. doi: 10.1097/00000421-198208000-00004. PMID: 6810689

Clinical prediction guides

Anatomo-functional study of the cerebellum in working memory in children treated for medulloblastoma.
Hoang DH, Pagnier A, Cousin E, Guichardet K, Schiff I, Icher C, Dilharreguy B, Grill J, Frappaz D, Berger C, Schneider F, Dubois-Teklali F, Krainik A
J Neuroradiol 2019 May;46(3):207-213. Epub 2019 Feb 5 doi: 10.1016/j.neurad.2019.01.093. PMID: 30731145
Neurocognitive dysfunction in adult cerebellar medulloblastoma.
Harrison RA, Kesler SR, Johnson JM, Penas-Prado M, Sullaway CM, Wefel JS
Psychooncology 2019 Jan;28(1):131-138. Epub 2018 Nov 5 doi: 10.1002/pon.4920. PMID: 30315720
Time perception in children treated for a cerebellar medulloblastoma.
Droit-Volet S, Zélanti PS, Dellatolas G, Kieffer V, El Massioui N, Brown BL, Doyère V, Provasi J, Grill J
Res Dev Disabil 2013 Jan;34(1):480-94. Epub 2012 Oct 9 doi: 10.1016/j.ridd.2012.09.006. PMID: 23063729
Genetic and expression profiles of cerebellar liponeurocytomas.
Horstmann S, Perry A, Reifenberger G, Giangaspero F, Huang H, Hara A, Masuoka J, Rainov NG, Bergmann M, Heppner FL, Brandner S, Chimelli L, Montagna N, Jackson T, Davis DG, Markesbery WR, Ellison DW, Weller RO, Taddei GL, Conti R, Del Bigio MR, González-Cámpora R, Radhakrishnan VV, Söylemezoglu F, Uro-Coste E, Qian J, Kleihues P, Ohgaki H
Brain Pathol 2004 Jul;14(3):281-9. doi: 10.1111/j.1750-3639.2004.tb00065.x. PMID: 15446583Free PMC Article
Adult cerebellar medulloblastoma: CT and MRI findings in eight cases.
de Carvalho Neto A, Gasparetto EL, Ono SE, Bertoldi GA, Gomes AF
Arq Neuropsiquiatr 2003 Jun;61(2A):199-203. Epub 2003 Jun 9 doi: 10.1590/s0004-282x2003000200008. PMID: 12806497

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