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Myelin-dependent gliosis

MedGen UID:
Concept ID:
Pathologic Function
HPO: HP:0006990


A type of gliosis that occurs in the vicinity of injured neurons. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMyelin-dependent gliosis

Conditions with this feature

Adducted thumbs-arthrogryposis syndrome, Christian type
MedGen UID:
Concept ID:
Disease or Syndrome
A type of arthrogryposis with characteristics of congenital cleft palate, microcephaly, craniostenosis and arthrogryposis. Additional features include facial dysmorphism. Velopharyngeal insufficiency with difficulties in swallowing, increased secretion of the nose and throat, prominent occiput, generalised muscular hypotonia with mild cyanosis and no spontaneous movements, seizures, torticollis, areflexia, intellectual disability, hypertrichosis of the lower extremities, and scleroedema are also observed. The disease often leads to early death. Transmission is autosomal recessive. No new cases have been described since 1983.

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