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Paraspinal neurofibroma

MedGen UID:
870537
•Concept ID:
C4024985
•
Neoplastic Process
Synonym: Paraspinal neurofibromas
 
HPO: HP:0006751

Definition

A neurofibroma (benign peripheral nerve sheath tumor) localized adjacent to the spine. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVParaspinal neurofibroma

Conditions with this feature

Neurofibromatosis, type III, mixed central and peripheral
MedGen UID:
419422
•Concept ID:
C2931480
•
Disease or Syndrome
See: Condition Record
Neurofibromatosis, type III, mixed central and peripheral

Professional guidelines

PubMed

MIBG in neuroblastoma diagnosis and treatment.
Olecki E, Grant CN
Semin Pediatr Surg 2019 Dec;28(6):150859. Epub 2019 Nov 20 doi: 10.1016/j.sempedsurg.2019.150859. PMID: 31931960
Management of Neuroblastoma: ICMR Consensus Document.
Bansal D, Totadri S, Chinnaswamy G, Agarwala S, Vora T, Arora B, Prasad M, Kapoor G, Radhakrishnan V, Laskar S, Kaur T, Rath GK, Bakhshi S
Indian J Pediatr 2017 Jun;84(6):446-455. Epub 2017 Apr 3 doi: 10.1007/s12098-017-2298-0. PMID: 28367616
Consensus guidelines for postoperative stereotactic body radiation therapy for spinal metastases: results of an international survey.
Redmond KJ, Lo SS, Soltys SG, Yamada Y, Barani IJ, Brown PD, Chang EL, Gerszten PC, Chao ST, Amdur RJ, De Salles AA, Guckenberger M, Teh BS, Sheehan J, Kersh CR, Fehlings MG, Sohn MJ, Chang UK, Ryu S, Gibbs IC, Sahgal A
J Neurosurg Spine 2017 Mar;26(3):299-306. Epub 2016 Nov 11 doi: 10.3171/2016.8.SPINE16121. PMID: 27834628Free PMC Article

Recent clinical studies

Etiology

Recent advances in the developmental origin of neuroblastoma: an overview.
Ponzoni M, Bachetti T, Corrias MV, Brignole C, Pastorino F, Calarco E, Bensa V, Giusto E, Ceccherini I, Perri P
J Exp Clin Cancer Res 2022 Mar 11;41(1):92. doi: 10.1186/s13046-022-02281-w. PMID: 35277192Free PMC Article
Diagnostic Pathology of Tumors of Peripheral Nerve.
Belakhoua SM, Rodriguez FJ
Neurosurgery 2021 Feb 16;88(3):443-456. doi: 10.1093/neuros/nyab021. PMID: 33588442Free PMC Article
Breast surgery and regional anaesthesia.
FitzGerald S, Odor PM, Barron A, Pawa A
Best Pract Res Clin Anaesthesiol 2019 Mar;33(1):95-110. Epub 2019 Apr 6 doi: 10.1016/j.bpa.2019.03.003. PMID: 31272657
Pediatric Non-vestibular Schwannoma.
Broehm C, Al-Ibraheemi A, Fritchie KJ
Pediatr Dev Pathol 2017 Jun;20(3):232-239. Epub 2017 Apr 18 doi: 10.1177/1093526617703540. PMID: 28420320
Consensus guidelines for postoperative stereotactic body radiation therapy for spinal metastases: results of an international survey.
Redmond KJ, Lo SS, Soltys SG, Yamada Y, Barani IJ, Brown PD, Chang EL, Gerszten PC, Chao ST, Amdur RJ, De Salles AA, Guckenberger M, Teh BS, Sheehan J, Kersh CR, Fehlings MG, Sohn MJ, Chang UK, Ryu S, Gibbs IC, Sahgal A
J Neurosurg Spine 2017 Mar;26(3):299-306. Epub 2016 Nov 11 doi: 10.3171/2016.8.SPINE16121. PMID: 27834628Free PMC Article

Diagnosis

Pineal/germ cell tumors and pineal parenchymal tumors.
Ogiwara H, Liao YM, Wong TT
Childs Nerv Syst 2023 Oct;39(10):2649-2665. Epub 2023 Oct 13 doi: 10.1007/s00381-023-06081-1. PMID: 37831207
Spinal Ganglioneuroma.
Goldberg JL, Tong J, McGrath LB Jr
World Neurosurg 2022 Jun;162:15-16. Epub 2022 Mar 17 doi: 10.1016/j.wneu.2022.03.046. PMID: 35306201
Diagnostic Pathology of Tumors of Peripheral Nerve.
Belakhoua SM, Rodriguez FJ
Neurosurgery 2021 Feb 16;88(3):443-456. doi: 10.1093/neuros/nyab021. PMID: 33588442Free PMC Article
Biological and Genetic Features of Neuroblastoma and Their Clinical Importance.
Aygun N
Curr Pediatr Rev 2018;14(2):73-90. doi: 10.2174/1573396314666180129101627. PMID: 29380702
Consensus guidelines for postoperative stereotactic body radiation therapy for spinal metastases: results of an international survey.
Redmond KJ, Lo SS, Soltys SG, Yamada Y, Barani IJ, Brown PD, Chang EL, Gerszten PC, Chao ST, Amdur RJ, De Salles AA, Guckenberger M, Teh BS, Sheehan J, Kersh CR, Fehlings MG, Sohn MJ, Chang UK, Ryu S, Gibbs IC, Sahgal A
J Neurosurg Spine 2017 Mar;26(3):299-306. Epub 2016 Nov 11 doi: 10.3171/2016.8.SPINE16121. PMID: 27834628Free PMC Article

Therapy

Modern Therapy for Spinal and Paraspinal Ewing Sarcoma: An Update of the University of Florida Experience.
Indelicato DJ, Vega RBM, Viviers E, Morris CG, Bradfield SM, Ranalli NJ, Bradley JA
Int J Radiat Oncol Biol Phys 2022 May 1;113(1):161-165. Epub 2022 Jan 13 doi: 10.1016/j.ijrobp.2022.01.007. PMID: 35033584
The quest to develop an effective therapy for neuroblastoma.
Bhoopathi P, Mannangatti P, Emdad L, Das SK, Fisher PB
J Cell Physiol 2021 Nov;236(11):7775-7791. Epub 2021 Apr 9 doi: 10.1002/jcp.30384. PMID: 33834508
Breast surgery and regional anaesthesia.
FitzGerald S, Odor PM, Barron A, Pawa A
Best Pract Res Clin Anaesthesiol 2019 Mar;33(1):95-110. Epub 2019 Apr 6 doi: 10.1016/j.bpa.2019.03.003. PMID: 31272657
Chordomas and chondrosarcomas-The role of radiation therapy.
De Amorim Bernstein K, DeLaney T
J Surg Oncol 2016 Oct;114(5):564-569. Epub 2016 Oct 19 doi: 10.1002/jso.24368. PMID: 27760458
Interventional procedures of the spine.
Santiago FR, Kelekis A, Alvarez LG, Filippiadis DK
Semin Musculoskelet Radiol 2014 Jul;18(3):309-17. Epub 2014 Jun 4 doi: 10.1055/s-0034-1375572. PMID: 24896746

Prognosis

The quest to develop an effective therapy for neuroblastoma.
Bhoopathi P, Mannangatti P, Emdad L, Das SK, Fisher PB
J Cell Physiol 2021 Nov;236(11):7775-7791. Epub 2021 Apr 9 doi: 10.1002/jcp.30384. PMID: 33834508
MIBG in neuroblastoma diagnosis and treatment.
Olecki E, Grant CN
Semin Pediatr Surg 2019 Dec;28(6):150859. Epub 2019 Nov 20 doi: 10.1016/j.sempedsurg.2019.150859. PMID: 31931960
Biological and Genetic Features of Neuroblastoma and Their Clinical Importance.
Aygun N
Curr Pediatr Rev 2018;14(2):73-90. doi: 10.2174/1573396314666180129101627. PMID: 29380702
Pediatric Non-vestibular Schwannoma.
Broehm C, Al-Ibraheemi A, Fritchie KJ
Pediatr Dev Pathol 2017 Jun;20(3):232-239. Epub 2017 Apr 18 doi: 10.1177/1093526617703540. PMID: 28420320
Primary ovarian neuroblastoma.
Muhlstein J, Rodriguez-Dahlhoff S, Marie B, Fouyssac F
J Pediatr Adolesc Gynecol 2010 Oct;23(5):263-6. Epub 2010 Apr 3 doi: 10.1016/j.jpag.2010.01.005. PMID: 20371194

Clinical prediction guides

Effect of Muscularity and Fatty Infiltration of Paraspinal Muscles on Outcome of Lumbar Interbody Fusion.
You KH, Cho M, Lee JH
J Korean Med Sci 2023 May 22;38(20):e151. doi: 10.3346/jkms.2023.38.e151. PMID: 37218352Free PMC Article
Spinal Ganglioneuroma.
Goldberg JL, Tong J, McGrath LB Jr
World Neurosurg 2022 Jun;162:15-16. Epub 2022 Mar 17 doi: 10.1016/j.wneu.2022.03.046. PMID: 35306201
Biological and Genetic Features of Neuroblastoma and Their Clinical Importance.
Aygun N
Curr Pediatr Rev 2018;14(2):73-90. doi: 10.2174/1573396314666180129101627. PMID: 29380702
Management of Neuroblastoma: ICMR Consensus Document.
Bansal D, Totadri S, Chinnaswamy G, Agarwala S, Vora T, Arora B, Prasad M, Kapoor G, Radhakrishnan V, Laskar S, Kaur T, Rath GK, Bakhshi S
Indian J Pediatr 2017 Jun;84(6):446-455. Epub 2017 Apr 3 doi: 10.1007/s12098-017-2298-0. PMID: 28367616
Dumbbell-Mimicked Mediastinal Angiomatosis.
Tang EK, Chu PT, Goan YG, Hsieh PP, Lin JC
Ann Thorac Surg 2016 Dec;102(6):e555-e556. doi: 10.1016/j.athoracsur.2016.05.051. PMID: 27847080

Recent systematic reviews

Stereotactic Radiosurgery for Postoperative Spine Malignancy: A Systematic Review and International Stereotactic Radiosurgery Society Practice Guidelines.
Faruqi S, Chen H, Fariselli L, Levivier M, Ma L, Paddick I, Pollock BE, Regis J, Sheehan J, Suh J, Yomo S, Sahgal A
Pract Radiat Oncol 2022 Mar-Apr;12(2):e65-e78. Epub 2021 Oct 19 doi: 10.1016/j.prro.2021.10.004. PMID: 34673275
A Systematic Review and Meta-Analysis of Erector Spinae Plane Block in Breast Surgery.
Allen G
AORN J 2021 Aug;114(2):193-196. doi: 10.1002/aorn.13475. PMID: 34314008
Analgesic efficacy and safety of erector spinae plane block in breast cancer surgery: a systematic review and meta-analysis.
Zhang Y, Liu T, Zhou Y, Yu Y, Chen G
BMC Anesthesiol 2021 Feb 20;21(1):59. doi: 10.1186/s12871-021-01277-x. PMID: 33610172Free PMC Article
Statistically significant but clinically unimportant: a systematic review and meta-analysis of the analgesic benefits of erector spinae plane block following breast cancer surgery.
Hussain N, Brull R, Noble J, Weaver T, Essandoh M, McCartney CJ, Abdallah FW
Reg Anesth Pain Med 2021 Jan;46(1):3-12. Epub 2020 Nov 9 doi: 10.1136/rapm-2020-101917. PMID: 33168651
Research synthesis: what is the diagnostic performance of magnetic resonance imaging to discriminate benign from malignant vertebral compression fractures? Systematic review and meta-analysis.
Thawait SK, Marcus MA, Morrison WB, Klufas RA, Eng J, Carrino JA
Spine (Phila Pa 1976) 2012 May 20;37(12):E736-44. doi: 10.1097/BRS.0b013e3182458cac. PMID: 22210011

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