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Absent atrioventricular node

MedGen UID:
870558
Concept ID:
C4025006
Finding
HPO: HP:0006681

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbsent atrioventricular node

Conditions with this feature

Congenital heart block
MedGen UID:
57432
Concept ID:
C0149530
Disease or Syndrome
Congenital heart block (CHB) is a rare disorder of atrioventricular conduction, characterized by absence of conduction of atrial impulses to the ventricles with slower ventricular rhythm (atrioventricular dissociation). CHB can occur in association with immunological evidence of maternal connective disease (autoimmune CHD), fetal structural CHD or can be idiopathic.

Professional guidelines

PubMed

Hamdan MH, Badhwar N, Scheinman MM
Card Electrophysiol Rev 2002 Dec;6(4):431-5. doi: 10.1023/a:1021144610712. PMID: 12438824
Crijns HJ, Van den Berg MP, Van Gelder IC, Van Veldhuisen DJ
Eur Heart J 1997 May;18 Suppl C:C45-9. doi: 10.1093/eurheartj/18.suppl_c.45. PMID: 9152675

Recent clinical studies

Etiology

Manolis AA, Manolis TA, Melita H, Manolis AS
Trends Cardiovasc Med 2020 Jul;30(5):275-286. Epub 2019 Jun 20 doi: 10.1016/j.tcm.2019.06.006. PMID: 31262557
Arora R, Spatz E, Vijayaraman P, Rosengarten M, Gross J, Kim S, Fisher J, Ferrick KJ
Pacing Clin Electrophysiol 2010 Aug;33(8):939-44. Epub 2010 May 4 doi: 10.1111/j.1540-8159.2010.02756.x. PMID: 20487338
Paul T, Bertram H, Bökenkamp R, Hausdorf G
Paediatr Drugs 2000 May-Jun;2(3):171-81. doi: 10.2165/00128072-200002030-00002. PMID: 10937468
Man KC, Brinkman K, Bogun F, Knight B, Bahu M, Weiss R, Goyal R, Harvey M, Daoud EG, Strickberger SA, Morady F
J Am Coll Cardiol 1996 Dec;28(7):1770-4. doi: 10.1016/S0735-1097(96)00415-9. PMID: 8962565
Sheahan RG, Klein GJ, Yee R, Le Feuvre CA, Krahn AD
Circulation 1996 Mar 1;93(5):969-72. doi: 10.1161/01.cir.93.5.969. PMID: 8598088

Diagnosis

Elayi CS, Morales G, Butt M, Shah J, Ogunbayo G, Misumida N, Catanzaro J, Di Biase L, Natale A, Delisle B, Darrat Y
J Interv Card Electrophysiol 2020 Nov;59(2):393-400. Epub 2019 Dec 9 doi: 10.1007/s10840-019-00658-0. PMID: 31820272
Manolis AA, Manolis TA, Melita H, Manolis AS
Trends Cardiovasc Med 2020 Jul;30(5):275-286. Epub 2019 Jun 20 doi: 10.1016/j.tcm.2019.06.006. PMID: 31262557
Ju YK, Liu J, Lee BH, Lai D, Woodcock EA, Lei M, Cannell MB, Allen DG
Circ Res 2011 Sep 30;109(8):848-57. Epub 2011 Aug 18 doi: 10.1161/CIRCRESAHA.111.243824. PMID: 21852551
Jat KR, Lodha R, Kabra SK
Indian J Pediatr 2011 Feb;78(2):211-8. Epub 2010 Oct 27 doi: 10.1007/s12098-010-0276-x. PMID: 20978872
Paul T, Bertram H, Bökenkamp R, Hausdorf G
Paediatr Drugs 2000 May-Jun;2(3):171-81. doi: 10.2165/00128072-200002030-00002. PMID: 10937468

Therapy

Manolis AA, Manolis TA, Melita H, Manolis AS
Trends Cardiovasc Med 2020 Jul;30(5):275-286. Epub 2019 Jun 20 doi: 10.1016/j.tcm.2019.06.006. PMID: 31262557
Tuohy S, Trulock KM, Wiggins NB, Bassiouny M, Ono M, Kiehl EL, Cantillon D, Tarakji K, Tanaka C, Dresing T, Saliba W, Varma N, Tchou P
J Cardiovasc Electrophysiol 2019 Sep;30(9):1569-1577. Epub 2019 Jul 2 doi: 10.1111/jce.14012. PMID: 31187543
Paul T, Bertram H, Bökenkamp R, Hausdorf G
Paediatr Drugs 2000 May-Jun;2(3):171-81. doi: 10.2165/00128072-200002030-00002. PMID: 10937468
Michalewicz L, Messerli FH
Am J Cardiol 1997 May 22;79(10A):39-46; discussion 47-8. doi: 10.1016/s0002-9149(97)00271-3. PMID: 9186066
Crijns HJ, Van den Berg MP, Van Gelder IC, Van Veldhuisen DJ
Eur Heart J 1997 May;18 Suppl C:C45-9. doi: 10.1093/eurheartj/18.suppl_c.45. PMID: 9152675

Prognosis

Elayi CS, Morales G, Butt M, Shah J, Ogunbayo G, Misumida N, Catanzaro J, Di Biase L, Natale A, Delisle B, Darrat Y
J Interv Card Electrophysiol 2020 Nov;59(2):393-400. Epub 2019 Dec 9 doi: 10.1007/s10840-019-00658-0. PMID: 31820272
Patil G, Phadke M, Lokhandwala Y, Shaikh Z, Nathani P, Mahajan A
Indian Heart J 2017 May-Jun;69(3):316-318. Epub 2016 Dec 21 doi: 10.1016/j.ihj.2016.12.008. PMID: 28648420Free PMC Article
Arora R, Spatz E, Vijayaraman P, Rosengarten M, Gross J, Kim S, Fisher J, Ferrick KJ
Pacing Clin Electrophysiol 2010 Aug;33(8):939-44. Epub 2010 May 4 doi: 10.1111/j.1540-8159.2010.02756.x. PMID: 20487338
Hamdan MH, Badhwar N, Scheinman MM
Card Electrophysiol Rev 2002 Dec;6(4):431-5. doi: 10.1023/a:1021144610712. PMID: 12438824
Hutchins GM, Liebman L, Moore GW, Gharagozloo F
Am J Pathol 1979 Jun;95(3):579-95. PMID: 453326Free PMC Article

Clinical prediction guides

de Almeida MC, Macías Y, Tretter JT, Sánchez-Quintana D, Cabrera JA, Spicer DE, Anderson RH
Heart Rhythm 2021 Nov;18(11):1990-1998. Epub 2021 Jul 30 doi: 10.1016/j.hrthm.2021.07.065. PMID: 34339846
Manolis AA, Manolis TA, Melita H, Manolis AS
Trends Cardiovasc Med 2020 Jul;30(5):275-286. Epub 2019 Jun 20 doi: 10.1016/j.tcm.2019.06.006. PMID: 31262557
Patil G, Phadke M, Lokhandwala Y, Shaikh Z, Nathani P, Mahajan A
Indian Heart J 2017 May-Jun;69(3):316-318. Epub 2016 Dec 21 doi: 10.1016/j.ihj.2016.12.008. PMID: 28648420Free PMC Article
Orlandi A, Hao H, Ferlosio A, Clément S, Hirota S, Spagnoli LG, Gabbiani G, Chaponnier C
Differentiation 2009 Apr;77(4):360-8. Epub 2009 Feb 4 doi: 10.1016/j.diff.2008.12.002. PMID: 19281784
Man KC, Brinkman K, Bogun F, Knight B, Bahu M, Weiss R, Goyal R, Harvey M, Daoud EG, Strickberger SA, Morady F
J Am Coll Cardiol 1996 Dec;28(7):1770-4. doi: 10.1016/S0735-1097(96)00415-9. PMID: 8962565

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