U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Enlarged sagittal diameter of the cervical canal

MedGen UID:
870664
Concept ID:
C4025118
Finding
HPO: HP:0005878

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEnlarged sagittal diameter of the cervical canal

Conditions with this feature

Syringomyelia, isolated
MedGen UID:
1622554
Concept ID:
C4538540
Disease or Syndrome
Syringomyelia (Greek: 'syrinx,' pipe, and 'myelos,' marrow) is a tubular cavity in the spinal cord. It can occur sporadically in association with spinal cord tumors, inflammatory arachnoiditis, or posttraumatically. It is rarely idiopathic (less than 1% of cases). The vast majority of cases of syringomyelia are cervical, noncommunicating, and associated with an abnormality at the foramen magnum, particularly the Chiari malformation type I (CM1; 118420), as well as basilar impression (109500) and Dandy-Walker malformation (220200) (Speer et al., 2003; Levine, 2004); these cases have shown familial segregation. The form of syringomyelia discussed here is 'noncommunicating' with the fourth ventricle, but may communicate with the subarachnoid space. In contrast, 'communicating' syringomyelia, or 'hydromelia,' opens rostrally into the fourth ventricle and almost always occurs in children with hydrocephalus, Chiari malformation type II (CM2; 207950), and spina bifida (see 182940) (Levine, 2004).

Recent clinical studies

Etiology

Zhang KR, Yang Y, Liu H, Wang BY, Ding C, Meng Y, Rong X, Hong Y
BMC Musculoskelet Disord 2021 Oct 15;22(1):881. doi: 10.1186/s12891-021-04773-w. PMID: 34654410Free PMC Article
Wang XN, Zhao YB, Lu XD, Zhao XF, Fan ZF, Qi DT, Zhou RT, Jin YZ, Zhao B
Orthop Surg 2021 Jul;13(5):1496-1504. Epub 2021 May 30 doi: 10.1111/os.13033. PMID: 34056862Free PMC Article
Struck AF, Carr CM, Shah V, Hesselink JR, Haughton VM
Neuroradiology 2016 Aug;58(8):771-5. Epub 2016 May 19 doi: 10.1007/s00234-016-1701-2. PMID: 27194170
Matveeva N, Janevski P, Nakeva N, Zhivadinovik J, Dodevski A
Pril (Makedon Akad Nauk Umet Odd Med Nauki) 2013;34(2):97-103. PMID: 24280784
Wang XY, Dai LY, Xu HZ, Chi YL
Spine (Phila Pa 1976) 2006 Nov 15;31(24):2863-70. doi: 10.1097/01.brs.0000245851.55012.f1. PMID: 17108843

Diagnosis

Zhang KR, Yang Y, Liu H, Wang BY, Ding C, Meng Y, Rong X, Hong Y
BMC Musculoskelet Disord 2021 Oct 15;22(1):881. doi: 10.1186/s12891-021-04773-w. PMID: 34654410Free PMC Article
Wang XN, Zhao YB, Lu XD, Zhao XF, Fan ZF, Qi DT, Zhou RT, Jin YZ, Zhao B
Orthop Surg 2021 Jul;13(5):1496-1504. Epub 2021 May 30 doi: 10.1111/os.13033. PMID: 34056862Free PMC Article
Struck AF, Carr CM, Shah V, Hesselink JR, Haughton VM
Neuroradiology 2016 Aug;58(8):771-5. Epub 2016 May 19 doi: 10.1007/s00234-016-1701-2. PMID: 27194170
Matveeva N, Janevski P, Nakeva N, Zhivadinovik J, Dodevski A
Pril (Makedon Akad Nauk Umet Odd Med Nauki) 2013;34(2):97-103. PMID: 24280784
Giménez-Roldán S, Benito C, Mateo D
J Neurol Sci 1978 Mar;36(1):135-46. doi: 10.1016/0022-510x(78)90167-3. PMID: 650252

Therapy

Lin C, Chen G, Li J, Shi L, Zhu Z, Wei F, Chen N, Liu S
Eur Radiol 2024 Feb;34(2):736-744. Epub 2023 Aug 15 doi: 10.1007/s00330-023-10032-4. PMID: 37581658
Zhang KR, Yang Y, Liu H, Wang BY, Ding C, Meng Y, Rong X, Hong Y
BMC Musculoskelet Disord 2021 Oct 15;22(1):881. doi: 10.1186/s12891-021-04773-w. PMID: 34654410Free PMC Article

Prognosis

Lin C, Chen G, Li J, Shi L, Zhu Z, Wei F, Chen N, Liu S
Eur Radiol 2024 Feb;34(2):736-744. Epub 2023 Aug 15 doi: 10.1007/s00330-023-10032-4. PMID: 37581658
Gu Z, Zhang A, Shen Y, Li F, Sun X, Ding W
Eur Spine J 2015 Aug;24(8):1613-20. Epub 2015 Jan 28 doi: 10.1007/s00586-015-3779-3. PMID: 25628021
Matveeva N, Janevski P, Nakeva N, Zhivadinovik J, Dodevski A
Pril (Makedon Akad Nauk Umet Odd Med Nauki) 2013;34(2):97-103. PMID: 24280784
Wang XY, Dai LY, Xu HZ, Chi YL
Spine (Phila Pa 1976) 2006 Nov 15;31(24):2863-70. doi: 10.1097/01.brs.0000245851.55012.f1. PMID: 17108843
Satomi K, Nishu Y, Kohno T, Hirabayashi K
Spine (Phila Pa 1976) 1994 Mar 1;19(5):507-10. doi: 10.1097/00007632-199403000-00003. PMID: 8184342

Clinical prediction guides

Wang XN, Zhao YB, Lu XD, Zhao XF, Fan ZF, Qi DT, Zhou RT, Jin YZ, Zhao B
Orthop Surg 2021 Jul;13(5):1496-1504. Epub 2021 May 30 doi: 10.1111/os.13033. PMID: 34056862Free PMC Article
Gu Z, Zhang A, Shen Y, Li F, Sun X, Ding W
Eur Spine J 2015 Aug;24(8):1613-20. Epub 2015 Jan 28 doi: 10.1007/s00586-015-3779-3. PMID: 25628021
Matveeva N, Janevski P, Nakeva N, Zhivadinovik J, Dodevski A
Pril (Makedon Akad Nauk Umet Odd Med Nauki) 2013;34(2):97-103. PMID: 24280784
Wang XY, Dai LY, Xu HZ, Chi YL
Spine (Phila Pa 1976) 2006 Nov 15;31(24):2863-70. doi: 10.1097/01.brs.0000245851.55012.f1. PMID: 17108843
Satomi K, Nishu Y, Kohno T, Hirabayashi K
Spine (Phila Pa 1976) 1994 Mar 1;19(5):507-10. doi: 10.1097/00007632-199403000-00003. PMID: 8184342

Supplemental Content

Table of contents

    Clinical resources

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...