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Temporal hypotrichosis

MedGen UID:
870856
Concept ID:
C4025316
Congenital Abnormality
Synonym: Reduced hair growth in temporal region
 
HPO: HP:0004524

Definition

Reduced or lacking hair growth in the temporal region (i.e., around the temples on the side of the skull). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTemporal hypotrichosis

Conditions with this feature

Pure hair and nail ectodermal dysplasia
MedGen UID:
400883
Concept ID:
C1865951
Disease or Syndrome
Pure hair and nail ectodermal dysplasia is characterised by the association of onychodystrophy and severe hypotrichosis, which is mainly limited to the scalp but may also affect the eyelashes and eyebrows. Less than 20 cases have been reported so far. The mode of transmission is autosomal dominant.

Professional guidelines

PubMed

Jin F, Wang Y, Wang Y, Qi H, Wang J
Pediatr Dermatol 2022 Mar;39(2):333-337. Epub 2022 Feb 17 doi: 10.1111/pde.14928. PMID: 35178778
Wolff H, Fischer TW, Blume-Peytavi U
Dtsch Arztebl Int 2016 May 27;113(21):377-86. doi: 10.3238/arztebl.2016.0377. PMID: 27504707Free PMC Article
Tanaka A, Akamatsu N, Shouzaki T, Toyota T, Yamano M, Nakagawa M, Tsuji S
Seizure 2013 Nov;22(9):772-5. Epub 2013 Jul 10 doi: 10.1016/j.seizure.2013.06.005. PMID: 23849689

Recent clinical studies

Etiology

Guan Z, Shi W, Ren M, Bi T, Su H
Skin Res Technol 2023 Mar;29(3):e13294. doi: 10.1111/srt.13294. PMID: 36973981Free PMC Article
Kasumagic-Halilovic E
Med Arch 2021 Apr;75(2):109-111. doi: 10.5455/medarh.2021.75.109-111. PMID: 34219869Free PMC Article
Pindado-Ortega C, Saceda-Corralo D, Moreno-Arrones ÓM, Rodrigues-Barata AR, Hermosa-Gelbard Á, Jaén-Olasolo P, Vañó-Galván S
J Am Acad Dermatol 2021 May;84(5):1285-1294. Epub 2020 Oct 7 doi: 10.1016/j.jaad.2020.09.093. PMID: 33038469
Acer E, Arslantaş D, Emiral GÖ, Ünsal A, Atalay BI, Göktaş S
An Bras Dermatol 2020 Jul-Aug;95(4):439-446. Epub 2020 Mar 20 doi: 10.1016/j.abd.2020.03.002. PMID: 32265054Free PMC Article
Heo JH, Yeom SD, Byun JW, Shin J, Choi GS
J Dermatol 2020 Apr;47(4):334-341. Epub 2020 Jan 9 doi: 10.1111/1346-8138.15220. PMID: 31919884

Diagnosis

Guan Z, Shi W, Ren M, Bi T, Su H
Skin Res Technol 2023 Mar;29(3):e13294. doi: 10.1111/srt.13294. PMID: 36973981Free PMC Article
Kasumagic-Halilovic E
Med Arch 2021 Apr;75(2):109-111. doi: 10.5455/medarh.2021.75.109-111. PMID: 34219869Free PMC Article
Egeberg A, Anderson S, Edson-Heredia E, Burge R
Clin Exp Dermatol 2021 Jun;46(4):651-656. Epub 2020 Dec 5 doi: 10.1111/ced.14507. PMID: 33175413
Wolff H, Fischer TW, Blume-Peytavi U
Dtsch Arztebl Int 2016 May 27;113(21):377-86. doi: 10.3238/arztebl.2016.0377. PMID: 27504707Free PMC Article
Springer K, Brown M, Stulberg DL
Am Fam Physician 2003 Jul 1;68(1):93-102. PMID: 12887115

Therapy

van den Elzen H, Schelke L, Velthuis P
J Cosmet Dermatol 2022 Feb;21(2):625-626. Epub 2021 Sep 15 doi: 10.1111/jocd.14453. PMID: 34525251Free PMC Article
Pindado-Ortega C, Saceda-Corralo D, Moreno-Arrones ÓM, Rodrigues-Barata AR, Hermosa-Gelbard Á, Jaén-Olasolo P, Vañó-Galván S
J Am Acad Dermatol 2021 May;84(5):1285-1294. Epub 2020 Oct 7 doi: 10.1016/j.jaad.2020.09.093. PMID: 33038469
Wolff H, Fischer TW, Blume-Peytavi U
Dtsch Arztebl Int 2016 May 27;113(21):377-86. doi: 10.3238/arztebl.2016.0377. PMID: 27504707Free PMC Article
Springer K, Brown M, Stulberg DL
Am Fam Physician 2003 Jul 1;68(1):93-102. PMID: 12887115
Koch-Weser J, Browne TR
N Engl J Med 1980 Mar 20;302(12):661-6. doi: 10.1056/NEJM198003203021204. PMID: 6766529

Prognosis

Redmond LC, Limbu S, Farjo B, Messenger AG, Higgins CA
Exp Dermatol 2023 Jul;32(7):1174-1181. Epub 2023 May 26 doi: 10.1111/exd.14839. PMID: 37237288Free PMC Article
Egeberg A, Anderson S, Edson-Heredia E, Burge R
Clin Exp Dermatol 2021 Jun;46(4):651-656. Epub 2020 Dec 5 doi: 10.1111/ced.14507. PMID: 33175413
Pindado-Ortega C, Saceda-Corralo D, Moreno-Arrones ÓM, Rodrigues-Barata AR, Hermosa-Gelbard Á, Jaén-Olasolo P, Vañó-Galván S
J Am Acad Dermatol 2021 May;84(5):1285-1294. Epub 2020 Oct 7 doi: 10.1016/j.jaad.2020.09.093. PMID: 33038469
Acer E, Arslantaş D, Emiral GÖ, Ünsal A, Atalay BI, Göktaş S
An Bras Dermatol 2020 Jul-Aug;95(4):439-446. Epub 2020 Mar 20 doi: 10.1016/j.abd.2020.03.002. PMID: 32265054Free PMC Article
Dawn G, Holmes SC, Moffat D, Munro CS
Clin Exp Dermatol 2003 Jan;28(1):43-5. doi: 10.1046/j.1365-2230.2003.01140.x. PMID: 12558629

Clinical prediction guides

Redmond LC, Limbu S, Farjo B, Messenger AG, Higgins CA
Exp Dermatol 2023 Jul;32(7):1174-1181. Epub 2023 May 26 doi: 10.1111/exd.14839. PMID: 37237288Free PMC Article
Jin F, Wang Y, Wang Y, Qi H, Wang J
Pediatr Dermatol 2022 Mar;39(2):333-337. Epub 2022 Feb 17 doi: 10.1111/pde.14928. PMID: 35178778
Pindado-Ortega C, Saceda-Corralo D, Moreno-Arrones ÓM, Rodrigues-Barata AR, Hermosa-Gelbard Á, Jaén-Olasolo P, Vañó-Galván S
J Am Acad Dermatol 2021 May;84(5):1285-1294. Epub 2020 Oct 7 doi: 10.1016/j.jaad.2020.09.093. PMID: 33038469
Natpracha W, Sukanjanapong S, Chanprapaph K, Suchonwanit P
J Cosmet Dermatol 2021 Mar;20(3):890-896. Epub 2020 Aug 11 doi: 10.1111/jocd.13642. PMID: 32783356
Lee S, Kim BJ, Lee CH, Lee WS
JAMA Dermatol 2019 May 1;155(5):564-571. doi: 10.1001/jamadermatol.2018.5894. PMID: 30916724Free PMC Article

Recent systematic reviews

Lee JA, Levy DA, Patel KG, Brennan E, Oyer SL
Laryngoscope 2021 Jan;131(1):59-66. Epub 2020 Feb 11 doi: 10.1002/lary.28551. PMID: 32045028
Carloni R, Pechevy L, Postel F, Zielinski M, Gandolfi S
J Plast Reconstr Aesthet Surg 2020 Dec;73(12):2210-2216. Epub 2020 May 22 doi: 10.1016/j.bjps.2020.05.035. PMID: 32536461

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