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Abnormality of superoxide metabolism

MedGen UID:
870879
•Concept ID:
C4025340
•
Finding
HPO: HP:0004358

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormality of superoxide metabolism

Professional guidelines

PubMed

Pregnancy-specific expression of protease-activated receptor 1: a therapeutic target for prevention and treatment of preeclampsia?
Walsh SW, Strauss JF 3rd
Am J Obstet Gynecol 2022 Feb;226(2S):S945-S953. doi: 10.1016/j.ajog.2021.11.1367. PMID: 35177224Free PMC Article
Development of novel small molecules for the treatment of ALS.
Mathew B, Ruiz P, Pathak V, Suto MJ
Bioorg Med Chem Lett 2020 Feb 15;30(4):126950. Epub 2020 Jan 7 doi: 10.1016/j.bmcl.2020.126950. PMID: 31928838
A risk-benefit assessment of drugs used for neonatal chronic lung disease.
Sweet DG, Halliday HL
Drug Saf 2000 May;22(5):389-404. doi: 10.2165/00002018-200022050-00006. PMID: 10830255

Recent clinical studies

Etiology

A review of nitric oxide and oxidative stress in typical ovulatory women and in the pathogenesis of ovulatory dysfunction in PCOS.
Awonuga AO, Camp OG, Abu-Soud HM
Reprod Biol Endocrinol 2023 Nov 23;21(1):111. doi: 10.1186/s12958-023-01159-6. PMID: 37996893Free PMC Article
Melatonin and alcohol-related disorders.
Kurhaluk N, Tkachenko H
Chronobiol Int 2020 Jun;37(6):781-803. Epub 2020 May 18 doi: 10.1080/07420528.2020.1761372. PMID: 32419511
Activity of enzymatic antioxidants in periodontitis: A systematic overview of the literature.
Toczewska J, Konopka T
Dent Med Probl 2019 Oct-Dec;56(4):419-426. doi: 10.17219/dmp/112151. PMID: 31895506
Role of copper in the process of spermatogenesis.
Ogórek M, Gąsior Ł, Pierzchała O, Daszkiewicz R, Lenartowicz M
Postepy Hig Med Dosw (Online) 2017 Aug 9;71(0):663-683. doi: 10.5604/01.3001.0010.3846. PMID: 28791960
Ion channels, long QT syndrome and arrhythmogenesis in ageing.
Jeevaratnam K, Chadda KR, Salvage SC, Valli H, Ahmad S, Grace AA, Huang CL
Clin Exp Pharmacol Physiol 2017 Dec;44 Suppl 1(Suppl Suppl 1):38-45. Epub 2017 Sep 20 doi: 10.1111/1440-1681.12721. PMID: 28024120Free PMC Article

Diagnosis

Lipid-Based Molecules on Signaling Pathways in Autism Spectrum Disorder.
Yui K, Imataka G, Yoshihara S
Int J Mol Sci 2022 Aug 29;23(17) doi: 10.3390/ijms23179803. PMID: 36077195Free PMC Article
Effect of Regulatory Network of Exosomes and microRNAs on Neurodegenerative Diseases.
Li D, Li YP, Li YX, Zhu XH, Du XG, Zhou M, Li WB, Deng HY
Chin Med J (Engl) 2018 Sep 20;131(18):2216-2225. doi: 10.4103/0366-6999.240817. PMID: 30203797Free PMC Article
NADPH Oxidases and Their Roles in Skin Homeostasis and Carcinogenesis.
Rudolf J, Raad H, Taieb A, Rezvani HR
Antioxid Redox Signal 2018 May 1;28(13):1238-1261. Epub 2017 Nov 17 doi: 10.1089/ars.2017.7282. PMID: 28990413
Neurologic damage in hypoglycemia.
Mohseni S
Handb Clin Neurol 2014;126:513-32. doi: 10.1016/B978-0-444-53480-4.00036-9. PMID: 25410242
Wilson disease.
Kitzberger R, Madl C, Ferenci P
Metab Brain Dis 2005 Dec;20(4):295-302. doi: 10.1007/s11011-005-7910-8. PMID: 16382340

Therapy

The double-edged roles of ROS in cancer prevention and therapy.
Wang Y, Qi H, Liu Y, Duan C, Liu X, Xia T, Chen D, Piao HL, Liu HX
Theranostics 2021;11(10):4839-4857. Epub 2021 Mar 4 doi: 10.7150/thno.56747. PMID: 33754031Free PMC Article
Neuroprotective Effect of Antioxidants in the Brain.
Lee KH, Cha M, Lee BH
Int J Mol Sci 2020 Sep 28;21(19) doi: 10.3390/ijms21197152. PMID: 32998277Free PMC Article
Steroid-induced osteonecrosis of the femoral head reveals enhanced reactive oxygen species and hyperactive osteoclasts.
Chen K, Liu Y, He J, Pavlos N, Wang C, Kenny J, Yuan J, Zhang Q, Xu J, He W
Int J Biol Sci 2020;16(11):1888-1900. Epub 2020 Apr 6 doi: 10.7150/ijbs.40917. PMID: 32398957Free PMC Article
Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent.
Fujimori K, Ishikawa M, Otomo A, Atsuta N, Nakamura R, Akiyama T, Hadano S, Aoki M, Saya H, Sobue G, Okano H
Nat Med 2018 Oct;24(10):1579-1589. Epub 2018 Aug 20 doi: 10.1038/s41591-018-0140-5. PMID: 30127392
The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity.
Cantó C, Houtkooper RH, Pirinen E, Youn DY, Oosterveer MH, Cen Y, Fernandez-Marcos PJ, Yamamoto H, Andreux PA, Cettour-Rose P, Gademann K, Rinsch C, Schoonjans K, Sauve AA, Auwerx J
Cell Metab 2012 Jun 6;15(6):838-47. doi: 10.1016/j.cmet.2012.04.022. PMID: 22682224Free PMC Article

Prognosis

Multiomics and machine-learning identify novel transcriptional and mutational signatures in amyotrophic lateral sclerosis.
Catanese A, Rajkumar S, Sommer D, Masrori P, Hersmus N, Van Damme P, Witzel S, Ludolph A, Ho R, Boeckers TM, Mulaw M
Brain 2023 Sep 1;146(9):3770-3782. doi: 10.1093/brain/awad075. PMID: 36883643Free PMC Article
Neuroprotective Effect of Antioxidants in the Brain.
Lee KH, Cha M, Lee BH
Int J Mol Sci 2020 Sep 28;21(19) doi: 10.3390/ijms21197152. PMID: 32998277Free PMC Article
Neurofilament Proteins as Prognostic Biomarkers in Neurological Disorders.
Lee Y, Lee BH, Yip W, Chou P, Yip BS
Curr Pharm Des 2020;25(43):4560-4569. doi: 10.2174/1381612825666191210154535. PMID: 31820696
Activity of enzymatic antioxidants in periodontitis: A systematic overview of the literature.
Toczewska J, Konopka T
Dent Med Probl 2019 Oct-Dec;56(4):419-426. doi: 10.17219/dmp/112151. PMID: 31895506
Effect of Regulatory Network of Exosomes and microRNAs on Neurodegenerative Diseases.
Li D, Li YP, Li YX, Zhu XH, Du XG, Zhou M, Li WB, Deng HY
Chin Med J (Engl) 2018 Sep 20;131(18):2216-2225. doi: 10.4103/0366-6999.240817. PMID: 30203797Free PMC Article

Clinical prediction guides

Clinical and functional spectrum of RAC2-related immunodeficiency.
Donkó Á, Sharapova SO, Kabat J, Ganesan S, Hauck FH, Bergerson JRE, Marois L, Abbott J, Moshous D, Williams KW, Campbell N, Martin PL, Lagresle-Peyrou C, Trojan T, Kuzmenko NB, Deordieva EA, Raykina EV, Abers MS, Abolhassani H, Barlogis V, Milla C, Hall G, Mousallem T, Church J, Kapoor N, Cros G, Chapdelaine H, Franco-Jarava C, Lopez-Lerma I, Miano M, Leiding JW, Klein C, Stasia MJ, Fischer A, Hsiao KC, Martelius T, Sepännen MRJ, Barmettler S, Walter J, Masmas TN, Mukhina AA, Falcone EL, Kracker S, Shcherbina A, Holland SM, Leto TL, Hsu AP
Blood 2024 Apr 11;143(15):1476-1487. doi: 10.1182/blood.2023022098. PMID: 38194689
Cryptotanshinone alleviates lipopolysaccharide and cigarette smoke-induced chronic obstructive pulmonary disease in mice via the Keap1/Nrf2 axis.
Song H, Jiang L, Yang W, Dai Y, Wang Y, Li Z, Liu P, Chen J
Biomed Pharmacother 2023 Sep;165:115105. Epub 2023 Jul 1 doi: 10.1016/j.biopha.2023.115105. PMID: 37399718
Multiomics and machine-learning identify novel transcriptional and mutational signatures in amyotrophic lateral sclerosis.
Catanese A, Rajkumar S, Sommer D, Masrori P, Hersmus N, Van Damme P, Witzel S, Ludolph A, Ho R, Boeckers TM, Mulaw M
Brain 2023 Sep 1;146(9):3770-3782. doi: 10.1093/brain/awad075. PMID: 36883643Free PMC Article
Lipid-Based Molecules on Signaling Pathways in Autism Spectrum Disorder.
Yui K, Imataka G, Yoshihara S
Int J Mol Sci 2022 Aug 29;23(17) doi: 10.3390/ijms23179803. PMID: 36077195Free PMC Article
Disease-modifying effects of metabolic perturbations in ALS/FTLD.
Jawaid A, Khan R, Polymenidou M, Schulz PE
Mol Neurodegener 2018 Dec 4;13(1):63. doi: 10.1186/s13024-018-0294-0. PMID: 30509290Free PMC Article

Recent systematic reviews

The role of nuclear factor erythroid 2-related factor 2 (NRF2) in normal and pathological pregnancy: A systematic review.
Tantengco OAG, de Castro Silva M, Shahin H, Bento GFC, Cursino GC, Cayenne S, da Silva MG, Menon R
Am J Reprod Immunol 2021 Dec;86(6):e13496. Epub 2021 Sep 19 doi: 10.1111/aji.13496. PMID: 34467607
Oxidative Stress in the Early Stage of Psychosis.
Ventriglio A, Bellomo A, Donato F, Iris B, Giovanna V, Dario DS, Edwige C, Di Gioia Ilaria, Pettorruso M, Perna G, Valchera A, De Berardis D
Curr Top Med Chem 2021 Oct 25;21(16):1457-1470. doi: 10.2174/1568026621666210701105839. PMID: 34218786
Withania somnifera (Ashwagandha) in neurobehavioural disorders induced by brain oxidative stress in rodents: a systematic review and meta-analysis.
Durg S, Dhadde SB, Vandal R, Shivakumar BS, Charan CS
J Pharm Pharmacol 2015 Jul;67(7):879-99. Epub 2015 Apr 1 doi: 10.1111/jphp.12398. PMID: 25828061
Circulating markers of oxidative stress and polycystic ovary syndrome (PCOS): a systematic review and meta-analysis.
Murri M, Luque-Ramírez M, Insenser M, Ojeda-Ojeda M, Escobar-Morreale HF
Hum Reprod Update 2013 May-Jun;19(3):268-88. Epub 2013 Jan 9 doi: 10.1093/humupd/dms059. PMID: 23303572

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