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Bone-in-a-bone appearance of carpal bones

MedGen UID:
870941
•Concept ID:
C4025403
•
Finding
Synonym: Bone-in-a-bone appearance of wrist bones
 
HPO: HP:0004234

Definition

The bone-in-bone sign is a radiographic finding produced by increased sclerosis (abnormally dense bone) occurring intermittently with zones of relatively normal bone density. This term should be used to describe such a finding in the carpal bones. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBone-in-a-bone appearance of carpal bones

Professional guidelines

PubMed

Trapeziometacarpal Osteoarthritis. Conservative and Surgical Treatment. A Diagnostic-Therapeutic Algorithm.
Kanak M, Rokicki R, Wojna J
Ortop Traumatol Rehabil 2023 Feb 28;25(1):23-32. doi: 10.5604/01.3001.0053.4027. PMID: 38078349
A systematic review of postoperative hand therapy management of basal joint arthritis.
Wolfe T, Chu JY, Woods T, Lubahn JD
Clin Orthop Relat Res 2014 Apr;472(4):1190-7. doi: 10.1007/s11999-013-3285-z. PMID: 24249530Free PMC Article
Lunotriquetral instability: diagnosis and treatment.
Shin AY, Battaglia MJ, Bishop AT
J Am Acad Orthop Surg 2000 May-Jun;8(3):170-9. doi: 10.5435/00124635-200005000-00004. PMID: 10874224

Recent clinical studies

Etiology

Outcomes of acute perilunate injuries-a systematic review.
Liechti R, Merky DN, Grobbelaar AO, van de Wall BJM, Vögelin E, Hirsiger S
Eur J Trauma Emerg Surg 2023 Oct;49(5):2071-2084. Epub 2023 Feb 7 doi: 10.1007/s00068-023-02222-y. PMID: 36750472
The outcome of bone graft surgery for nonunion of fractures of the scaphoid.
Ammori MB, Elvey M, Mahmoud SS, Nicholls AJ, Robinson S, Rowan C, Spence S, Wade RG, Karantana A; British Society for Surgery of the Hand Scaphoid Nonunion Group, Davis TRC
J Hand Surg Eur Vol 2019 Sep;44(7):676-684. Epub 2019 May 20 doi: 10.1177/1753193419841278. PMID: 31109228Free PMC Article
Pros and cons for the medical age assessments in unaccompanied minors: a mini-review.
De Sanctis V, Soliman AT, Soliman NA, Elalaily R, Di Maio S, Bedair EM, Kassem I, Millimaggi G
Acta Biomed 2016 Sep 13;87(2):121-31. PMID: 27648992
Chondrosarcomas of the hands and feet: A case series and systematic review of the literature.
Fayad LM, Ahlawat S, Khan MS, McCarthy E
Eur J Radiol 2015 Oct;84(10):2004-12. Epub 2015 Jul 2 doi: 10.1016/j.ejrad.2015.06.026. PMID: 26189572
A systematic review of postoperative hand therapy management of basal joint arthritis.
Wolfe T, Chu JY, Woods T, Lubahn JD
Clin Orthop Relat Res 2014 Apr;472(4):1190-7. doi: 10.1007/s11999-013-3285-z. PMID: 24249530Free PMC Article

Diagnosis

Screw Fixation Alone for Scaphoid Fracture Nonunion.
Ernst SMC, Green DP, Saucedo JM
J Hand Surg Am 2018 Sep;43(9):837-843. Epub 2018 Jun 20 doi: 10.1016/j.jhsa.2018.03.048. PMID: 29934086
The Role of Wrist Arthroscopy in Kienbock Disease.
MacLean SBM, Kantar K, Bain GI, Lichtman DM
Hand Clin 2017 Nov;33(4):727-734. doi: 10.1016/j.hcl.2017.07.003. PMID: 28991584
Hook of the Hamate: The Spectrum of Often Missed Pathologic Findings.
Davis DL
AJR Am J Roentgenol 2017 Nov;209(5):1110-1118. Epub 2017 Aug 23 doi: 10.2214/AJR.17.18043. PMID: 28834449Free PMC Article
Dynamic high-resolution ultrasound of intrinsic and extrinsic ligaments of the wrist: How to make it simple.
Gitto S, Messina C, Mauri G, Aliprandi A, Sardanelli F, Sconfienza LM
Eur J Radiol 2017 Feb;87:20-35. Epub 2016 Dec 5 doi: 10.1016/j.ejrad.2016.12.002. PMID: 28065372
Kienböck's disease.
Beredjiklian PK
J Hand Surg Am 2009 Jan;34(1):167-75. doi: 10.1016/j.jhsa.2008.10.012. PMID: 19121745

Therapy

Systematic Review of the Use of Power Doppler Ultrasound in the Imaging of Peripheral Nerve Compression Neuropathy.
Landau AJ, Parameswaran P, Fresco R, Simon L, Dy CJ, Brogan DM
Plast Reconstr Surg 2022 Jan 1;149(1):48e-56e. doi: 10.1097/PRS.0000000000008627. PMID: 34936616
Preoperative Antibiotics in Wrist Arthroscopy.
Hoel RJ, Mittelsteadt MJ, Samborski SA, Bohn DC
J Hand Surg Am 2018 Nov;43(11):987-991.e1. Epub 2018 May 16 doi: 10.1016/j.jhsa.2018.03.040. PMID: 29778348
Reproducibility of X-rays and CT arthrography in SLAC, SNAC, SCAC wrists.
Belhaouane R, Lebeau N, Maes-Clavier C, Hustin C, Krief E, Bonnaire B, Warin M, Rotari V, David E
Hand Surg Rehabil 2016 Dec;35(6):393-400. Epub 2016 Sep 20 doi: 10.1016/j.hansur.2016.08.006. PMID: 27890247
A systematic review of postoperative hand therapy management of basal joint arthritis.
Wolfe T, Chu JY, Woods T, Lubahn JD
Clin Orthop Relat Res 2014 Apr;472(4):1190-7. doi: 10.1007/s11999-013-3285-z. PMID: 24249530Free PMC Article
Silicone implants.
Kleinert JM, Lister GD
Hand Clin 1986 May;2(2):271-90. PMID: 2939096

Prognosis

Substantial Increase in the Incidence of Surgery for Osteoarthritis of the Base of the Thumb Between 1997 and 2019 in Finland.
Myohanen M, Waris E, Nordback PH, Mattila S, Aspinen S
In Vivo 2022 Mar-Apr;36(2):833-838. doi: 10.21873/invivo.12770. PMID: 35241539Free PMC Article
Carpals and epiphyses of radius and ulna as age indicators using longitudinal data: a Bayesian approach.
Cameriere R, Bestetti F, Velandia Palacio LA, Riccomi G, Skrami E, Parente V, Ferrante L
Int J Legal Med 2019 Jan;133(1):197-204. Epub 2018 Mar 7 doi: 10.1007/s00414-018-1807-7. PMID: 29516251
Validity of computed tomography in predicting scaphoid screw prominence: a cadaveric study.
Griffis CE, Olsen C, Nesti L, Gould CF, Frew M, McKay P
Arch Orthop Trauma Surg 2017 Apr;137(4):573-577. Epub 2017 Mar 4 doi: 10.1007/s00402-017-2658-2. PMID: 28260129
Turner syndrome and osteoporosis: mechanisms and prognosis.
Rubin K
Pediatrics 1998 Aug;102(2 Pt 3):481-5. PMID: 9685448
Lunotriquetral sprains.
Reagan DS, Linscheid RL, Dobyns JH
J Hand Surg Am 1984 Jul;9(4):502-14. doi: 10.1016/s0363-5023(84)80101-x. PMID: 6747234

Clinical prediction guides

Preiser disease in a child before complete ossification of the scaphoid: a case report.
Fujibuchi T, Imai H, Jono A, Kiyomatsu H, Miura H
BMC Musculoskelet Disord 2022 Mar 18;23(1):265. doi: 10.1186/s12891-022-05226-8. PMID: 35303840Free PMC Article
Lunate biomechanics: application to Kienböck's disease and its treatment.
Camus EJ, Van Overstraeten L, Schuind F
Hand Surg Rehabil 2021 Apr;40(2):117-125. Epub 2020 Dec 10 doi: 10.1016/j.hansur.2020.10.017. PMID: 33309792
Radial longitudinal deficiency. Analysis of clinical and radiological results.
Vergara-Amador E, López Rincón L, Herrera Rodríguez S
Rev Esp Cir Ortop Traumatol (Engl Ed) 2019 May-Jun;63(3):217-226. Epub 2018 Dec 9 doi: 10.1016/j.recot.2018.10.004. PMID: 30541698
Pros and cons for the medical age assessments in unaccompanied minors: a mini-review.
De Sanctis V, Soliman AT, Soliman NA, Elalaily R, Di Maio S, Bedair EM, Kassem I, Millimaggi G
Acta Biomed 2016 Sep 13;87(2):121-31. PMID: 27648992
Radial shortening.
Weiss AP
Hand Clin 1993 Aug;9(3):475-82. PMID: 8408257

Recent systematic reviews

Outcomes of acute perilunate injuries-a systematic review.
Liechti R, Merky DN, Grobbelaar AO, van de Wall BJM, Vögelin E, Hirsiger S
Eur J Trauma Emerg Surg 2023 Oct;49(5):2071-2084. Epub 2023 Feb 7 doi: 10.1007/s00068-023-02222-y. PMID: 36750472
Systematic Review of the Use of Power Doppler Ultrasound in the Imaging of Peripheral Nerve Compression Neuropathy.
Landau AJ, Parameswaran P, Fresco R, Simon L, Dy CJ, Brogan DM
Plast Reconstr Surg 2022 Jan 1;149(1):48e-56e. doi: 10.1097/PRS.0000000000008627. PMID: 34936616
Chondrosarcomas of the hands and feet: A case series and systematic review of the literature.
Fayad LM, Ahlawat S, Khan MS, McCarthy E
Eur J Radiol 2015 Oct;84(10):2004-12. Epub 2015 Jul 2 doi: 10.1016/j.ejrad.2015.06.026. PMID: 26189572
A systematic review of postoperative hand therapy management of basal joint arthritis.
Wolfe T, Chu JY, Woods T, Lubahn JD
Clin Orthop Relat Res 2014 Apr;472(4):1190-7. doi: 10.1007/s11999-013-3285-z. PMID: 24249530Free PMC Article
Osseous and ligamentous scaphoid anatomy: Part I. A systematic literature review highlighting controversies.
Buijze GA, Lozano-Calderon SA, Strackee SD, Blankevoort L, Jupiter JB
J Hand Surg Am 2011 Dec;36(12):1926-35. Epub 2011 Nov 3 doi: 10.1016/j.jhsa.2011.09.012. PMID: 22051230

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