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Sclerotic humeral metaphysis

MedGen UID:
871045
Concept ID:
C4025509
Disease or Syndrome
Synonyms: Hardening of wide portion of long bone of upper arm; Stiffening of wide portion of long bone of upper arm
 
HPO: HP:0003918

Conditions with this feature

Spondylometaphyseal dysplasia, A4 type
MedGen UID:
324620
Concept ID:
C1836862
Disease or Syndrome
The spondylometaphyseal dysplasias are a relatively common, heterogeneous group of disorders characterized by spinal and metaphyseal changes of variable pattern and severity. The classification of spondylometaphyseal dysplasias of Maroteaux and Spranger (1991) was based on changes of the femoral neck and the shape of vertebral anomalies. In this classification, type A4 referred to a form with severe metaphyseal changes of the femoral neck and ovoid, flattened vertebral bodies with anterior tongue-like deformities.

Recent clinical studies

Etiology

Nguyen JC, Lin B, Potter HG
Skeletal Radiol 2019 Jul;48(7):1087-1094. Epub 2019 Jan 3 doi: 10.1007/s00256-018-3130-2. PMID: 30607454
Maheshwari AV, Jelinek JS, Song AJ, Nelson KJ, Murphey MD, Henshaw RM
Skeletal Radiol 2011 Dec;40(12):1563-73. Epub 2011 Jul 20 doi: 10.1007/s00256-011-1227-y. PMID: 21773875
Silva EC, Terreri MT, de Castro TC, Barbosa CP, Fernandes AR, Hilário MO
Rev Bras Reumatol 2010 May-Jun;50(3):283-90. PMID: 21125164
Potter BK, Freedman BA, Lehman RA Jr, Shawen SB, Kuklo TR, Murphey MD
J Bone Joint Surg Am 2005 Jul;87(7):1551-60. doi: 10.2106/JBJS.D.02404. PMID: 15995123
Kumar VP, Pang M, Pho RW
Ann Acad Med Singap 1981 Jul;10(3):317-22. PMID: 7332302

Diagnosis

Agarwal A, Rastogi A
J Hand Surg Asian Pac Vol 2017 Dec;22(4):457-463. doi: 10.1142/S0218810417500502. PMID: 29117827
Maheshwari AV, Jelinek JS, Song AJ, Nelson KJ, Murphey MD, Henshaw RM
Skeletal Radiol 2011 Dec;40(12):1563-73. Epub 2011 Jul 20 doi: 10.1007/s00256-011-1227-y. PMID: 21773875
Potter BK, Freedman BA, Lehman RA Jr, Shawen SB, Kuklo TR, Murphey MD
J Bone Joint Surg Am 2005 Jul;87(7):1551-60. doi: 10.2106/JBJS.D.02404. PMID: 15995123
Aizawa T, Okada K, Abe E, Tsuchida S, Shimada Y, Itoi E
Skeletal Radiol 2004 Jan;33(1):41-5. Epub 2003 Nov 20 doi: 10.1007/s00256-003-0717-y. PMID: 14628102
Priolo F, Cerase A
Eur J Radiol 1998 May;27 Suppl 1:S77-85. doi: 10.1016/s0720-048x(98)00047-3. PMID: 9652506

Therapy

Agarwal A, Rastogi A
J Hand Surg Asian Pac Vol 2017 Dec;22(4):457-463. doi: 10.1142/S0218810417500502. PMID: 29117827
Silva EC, Terreri MT, de Castro TC, Barbosa CP, Fernandes AR, Hilário MO
Rev Bras Reumatol 2010 May-Jun;50(3):283-90. PMID: 21125164

Prognosis

Priolo F, Cerase A
Eur J Radiol 1998 May;27 Suppl 1:S77-85. doi: 10.1016/s0720-048x(98)00047-3. PMID: 9652506

Clinical prediction guides

Agarwal A, Rastogi A
J Hand Surg Asian Pac Vol 2017 Dec;22(4):457-463. doi: 10.1142/S0218810417500502. PMID: 29117827
Silva EC, Terreri MT, de Castro TC, Barbosa CP, Fernandes AR, Hilário MO
Rev Bras Reumatol 2010 May-Jun;50(3):283-90. PMID: 21125164

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