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Atlantoaxial abnormality

MedGen UID:
871145
Concept ID:
C4025617
Anatomical Abnormality
HPO: HP:0003413

Definition

An anomaly of the atlantoaxial joint, i.e., of the joint between the first (atlas) and second (axis) cervical vertebrae. [from HPO]

Professional guidelines

PubMed

Tsou AY, Bulova P, Capone G, Chicoine B, Gelaro B, Harville TO, Martin BA, McGuire DE, McKelvey KD, Peterson M, Tyler C, Wells M, Whitten MS; Global Down Syndrome Foundation Medical Care Guidelines for Adults with Down Syndrome Workgroup
JAMA 2020 Oct 20;324(15):1543-1556. doi: 10.1001/jama.2020.17024. PMID: 33079159
Helenius IJ, Bauer JM, Verhofste B, Sponseller PD, Krengel WF, Hedequist D, Cahill PJ, Larson AN, Pahys JM, Anderson JT, Martus JE, Yaszay B, Phillips JH
J Bone Joint Surg Am 2019 Oct 2;101(19):1750-1760. doi: 10.2106/JBJS.19.00314. PMID: 31577680
Cohen SP
Mayo Clin Proc 2015 Feb;90(2):284-99. doi: 10.1016/j.mayocp.2014.09.008. PMID: 25659245

Recent clinical studies

Etiology

Stadler JA 3rd
Neurosurg Clin N Am 2022 Jan;33(1):61-65. Epub 2021 Oct 27 doi: 10.1016/j.nec.2021.09.012. PMID: 34801142
Tsou AY, Bulova P, Capone G, Chicoine B, Gelaro B, Harville TO, Martin BA, McGuire DE, McKelvey KD, Peterson M, Tyler C, Wells M, Whitten MS; Global Down Syndrome Foundation Medical Care Guidelines for Adults with Down Syndrome Workgroup
JAMA 2020 Oct 20;324(15):1543-1556. doi: 10.1001/jama.2020.17024. PMID: 33079159
Henderson FC Sr, Austin C, Benzel E, Bolognese P, Ellenbogen R, Francomano CA, Ireton C, Klinge P, Koby M, Long D, Patel S, Singman EL, Voermans NC
Am J Med Genet C Semin Med Genet 2017 Mar;175(1):195-211. Epub 2017 Feb 21 doi: 10.1002/ajmg.c.31549. PMID: 28220607
Cormier-Daire V
Best Pract Res Clin Rheumatol 2008 Mar;22(1):33-44. doi: 10.1016/j.berh.2007.12.009. PMID: 18328979
Hayes A, Batshaw ML
Pediatr Clin North Am 1993 Jun;40(3):523-35. doi: 10.1016/s0031-3955(16)38548-0. PMID: 8493063

Diagnosis

Tsou AY, Bulova P, Capone G, Chicoine B, Gelaro B, Harville TO, Martin BA, McGuire DE, McKelvey KD, Peterson M, Tyler C, Wells M, Whitten MS; Global Down Syndrome Foundation Medical Care Guidelines for Adults with Down Syndrome Workgroup
JAMA 2020 Oct 20;324(15):1543-1556. doi: 10.1001/jama.2020.17024. PMID: 33079159
Chatterjee S, Shivhare P, Verma SG
Childs Nerv Syst 2019 Oct;35(10):1755-1761. Epub 2019 Jul 13 doi: 10.1007/s00381-019-04284-z. PMID: 31302728
Henderson FC Sr, Austin C, Benzel E, Bolognese P, Ellenbogen R, Francomano CA, Ireton C, Klinge P, Koby M, Long D, Patel S, Singman EL, Voermans NC
Am J Med Genet C Semin Med Genet 2017 Mar;175(1):195-211. Epub 2017 Feb 21 doi: 10.1002/ajmg.c.31549. PMID: 28220607
Cohen SP
Mayo Clin Proc 2015 Feb;90(2):284-99. doi: 10.1016/j.mayocp.2014.09.008. PMID: 25659245
Hayes A, Batshaw ML
Pediatr Clin North Am 1993 Jun;40(3):523-35. doi: 10.1016/s0031-3955(16)38548-0. PMID: 8493063

Therapy

Liu S, Liu B, Liang G, Chen Q, Wang H, Lin Y
J Orthop Surg Res 2022 Mar 28;17(1):183. doi: 10.1186/s13018-022-03077-6. PMID: 35346286Free PMC Article
Du YQ, Yin YH, Li T, Qiao GY, Yu XG
Eur Spine J 2021 Jun;30(6):1585-1595. Epub 2021 Mar 11 doi: 10.1007/s00586-021-06780-w. PMID: 33704580
Husnudinov RE, Ibrahim GM, Propst EJ, Wolter NE
Int J Pediatr Otorhinolaryngol 2018 Nov;114:36-43. Epub 2018 Aug 27 doi: 10.1016/j.ijporl.2018.08.029. PMID: 30262364
Elliott RE, Tanweer O, Boah A, Morsi A, Ma T, Frempong-Boadu A, Smith ML
J Spinal Disord Tech 2014 Feb;27(1):11-28. doi: 10.1097/BSD.0b013e318277da19. PMID: 23128387
Ahmed R, Traynelis VC, Menezes AH
Childs Nerv Syst 2008 Oct;24(10):1209-24. Epub 2008 Apr 4 doi: 10.1007/s00381-008-0607-7. PMID: 18389260

Prognosis

Yan J, Qiu C, Fu L, Liu X, Zheng Y
Spine (Phila Pa 1976) 2023 Jul 1;48(13):962-968. Epub 2023 Mar 15 doi: 10.1097/BRS.0000000000004626. PMID: 36940257
Rehman RU, Akhtar MS, Bibi A, Shah SM, Khan S, Kashif M
World Neurosurg 2022 Sep;165:27-44. Epub 2022 Jun 11 doi: 10.1016/j.wneu.2022.06.024. PMID: 35700863
Huang PJ, Lin JH, Chiang YH
World Neurosurg 2020 Jun;138:e634-e641. Epub 2020 Mar 13 doi: 10.1016/j.wneu.2020.03.023. PMID: 32173550
Cormier-Daire V
Best Pract Res Clin Rheumatol 2008 Mar;22(1):33-44. doi: 10.1016/j.berh.2007.12.009. PMID: 18328979
Hayes A, Batshaw ML
Pediatr Clin North Am 1993 Jun;40(3):523-35. doi: 10.1016/s0031-3955(16)38548-0. PMID: 8493063

Clinical prediction guides

Goel A, Vutha R, Shah A
Adv Tech Stand Neurosurg 2023;46:125-147. doi: 10.1007/978-3-031-28202-7_7. PMID: 37318573
Zhu H, Xu R, Wang S, Xia H, Yan Y, Xia Y
World Neurosurg 2023 Jul;175:e1017-e1024. Epub 2023 Apr 21 doi: 10.1016/j.wneu.2023.04.064. PMID: 37087038
Wang Y, Song C, Ji Y, Xia J, Chen C, Haque M, Zhuang J, Zhou C, Zu J, Li X, Yan J
World Neurosurg 2023 Mar;171:e1-e7. Epub 2022 Aug 29 doi: 10.1016/j.wneu.2022.08.108. PMID: 36049725
Hendriksz CJ, Harmatz P, Beck M, Jones S, Wood T, Lachman R, Gravance CG, Orii T, Tomatsu S
Mol Genet Metab 2013 Sep-Oct;110(1-2):54-64. Epub 2013 Apr 10 doi: 10.1016/j.ymgme.2013.04.002. PMID: 23665161Free PMC Article
Menezes AH
J Neurosurg Pediatr 2012 Jun;9(6):573-85. doi: 10.3171/2012.2.PEDS11371. PMID: 22656246

Recent systematic reviews

Sae-Huang M, Borg A, Hill CS
J Neurosurg Pediatr 2020 Oct 9;27(1):108-119. doi: 10.3171/2020.6.PEDS20396. PMID: 33036001
Hofler RC, Pecoraro N, Jones GA
World Neurosurg 2019 Jun;126:e125-e135. Epub 2019 Feb 18 doi: 10.1016/j.wneu.2019.01.267. PMID: 30790735
Onyewu O, Manchikanti L, Falco FJ, Singh V, Geffert S, Helm S 2nd, Cohen SP, Hirsch JA
Pain Physician 2012 Nov-Dec;15(6):E777-806. PMID: 23159976
Karkos PD, Benton J, Leong SC, Mushi E, Sivaji N, Assimakopoulos DA
Int J Pediatr Otorhinolaryngol 2007 Dec;71(12):1823-7. Epub 2007 Aug 13 doi: 10.1016/j.ijporl.2007.07.002. PMID: 17706297
Brockmeyer D
Pediatr Neurosurg 1999 Aug;31(2):71-7. doi: 10.1159/000028837. PMID: 10592475

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